penicillamine has been researched along with Clinically Isolated CNS Demyelinating Syndrome in 3 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "While the demyelination alone is sufficient to block conduction and thereby cause symptoms, there is increasing evidence that the inflammation may also contribute significantly to the conduction block, although the mechanisms are not understood." | 1.30 | Nitric oxide donors reversibly block axonal conduction: demyelinated axons are especially susceptible. ( Kapoor, R; Redford, EJ; Smith, KJ, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mitrovic, B | 1 |
| Ignarro, LJ | 1 |
| Montestruque, S | 1 |
| Smoll, A | 1 |
| Merrill, JE | 1 |
| Redford, EJ | 1 |
| Kapoor, R | 1 |
| Smith, KJ | 1 |
| Pedersen, PB | 1 |
| Hogenhaven, H | 1 |
3 other studies available for penicillamine and Clinically Isolated CNS Demyelinating Syndrome
| Article | Year |
|---|---|
Nitric oxide as a potential pathological mechanism in demyelination: its differential effects on primary glial cells in vitro.
Topics: Animals; Astrocytes; Demyelinating Diseases; DNA Damage; Hemoglobins; Isocitrate Dehydrogenase; Micr | 1994 |
Nitric oxide donors reversibly block axonal conduction: demyelinated axons are especially susceptible.
Topics: Animals; Axons; Cattle; Demyelinating Diseases; Ethidium; Lysophosphatidylcholines; Microinjections; | 1997 |
Penicillamin-induced neuropathy in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Demyelinating Diseases; Dose-Response Relationship, Drug; Evoked Potentials, | 1990 |