penicillamine has been researched along with Cholera Infantum in 29 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "After a controlled, double blind multicenter trial of D-penicillamine in the treatment of rheumatoid arthritis, 148 patients were followed for an additional year in an open label trial." | 9.06 | Toxicity of longterm low dose D-penicillamine therapy in rheumatoid arthritis. Cooperative Systematic Studies of Rheumatic Disease Group. ( , 1987) |
| "Adverse effects to D-penicillamine were studied prospectively over 3 years in 259 patients with rheumatoid arthritis." | 7.66 | Adverse effects of D-penicillamine in rheumatoid arthritis. ( Atkins, CJ; Offer, RC; Patterson, AC; Robinson, HS; Stein, HB; Teufel, A, 1980) |
| "A retrospective study of penicillamine toxicity in 156 patients yielded a high incidence of toxic reaction (62%), necessitating discontinuation of the drug therapy in 36% of the patients." | 5.26 | Toxicity of penicillamine. A serious limitation to therapy in rheumatoid arthritis. ( Bernhard, GC; Goldman, AL; Halverson, PB; Kozin, F, 1978) |
| "After a controlled, double blind multicenter trial of D-penicillamine in the treatment of rheumatoid arthritis, 148 patients were followed for an additional year in an open label trial." | 5.06 | Toxicity of longterm low dose D-penicillamine therapy in rheumatoid arthritis. Cooperative Systematic Studies of Rheumatic Disease Group. ( , 1987) |
| "Adverse effects to D-penicillamine were studied prospectively over 3 years in 259 patients with rheumatoid arthritis." | 3.66 | Adverse effects of D-penicillamine in rheumatoid arthritis. ( Atkins, CJ; Offer, RC; Patterson, AC; Robinson, HS; Stein, HB; Teufel, A, 1980) |
| " Data about the dosage scheme of zinc sulphate, side effects and efficacy and toxicity of the treatment were collected and recorded in the patient's medical chart at each visit to the hospital." | 1.39 | Gastrointestinal side effects in children with Wilson's disease treated with zinc sulphate. ( Avsar, Y; Dądalski, M; Jańczyk, W; Schmidt, H; Socha, P; Wiernicka, A, 2013) |
| "The connective tissue disease systemic sclerosis (SSc) is still a challenge to every rheumatologist." | 1.33 | [Systemic sclerosis--a challenge in rheumatology]. ( Müller-Ladner, U; Saar, P, 2006) |
| "To evaluate rates on the adverse side effect and discontinuation of second-line drugs frequently used in the treatment of rheumatoid arthritis (RA)." | 1.31 | [Retrospective study of adverse events in patients with rheumatoid arthritis treated with second-line drugs]. ( Jiang, L; Ni, L; Zhao, N, 2002) |
| " A preliminary bioavailability study of two of the lead structures is presented." | 1.27 | Antiinflammatory activity of substituted 6-hydroxypyrimido[2,1-f]purine-2,4,8(1H,3H,9H)-triones. Atypical nonsteroidal antiinflammatory agents. ( Blythin, DJ; Bober, LA; Chiu, PJ; Conn, DJ; Domalski, MS; Kaminski, JJ; Solomon, DM; Spitler, J; Verbiar, LL; Wong, SC, 1986) |
| "The majority of patients were being treated for rheumatoid arthritis." | 1.27 | European League against Rheumatism study of adverse reactions to D-penicillamine. ( Kay, A, 1986) |
| "The bioavailability of D-penicillamine was measured in 24 patients with generalized scleroderma (Progressive Systemic Sclerosis, PSS)." | 1.27 | Bioavailability of D-penicillamine in relation to gastrointestinal involvement of generalized scleroderma. ( Ammitzbøll, T; Asboe-Hansen, G; Hendel, L; Kreuzig, F, 1987) |
| " D-penicillamine bioavailability was examined after oral, duodenal, intravenous and rectal administration." | 1.27 | Bioavailability of D-penicillamine in a patient with gastrointestinal progressive systemic sclerosis. ( Ammitzbøll, T; Asboe-Hansen, G; Hendel, L; Kreuzig, F; Worning, H, 1986) |
| "A retrospective study of penicillamine toxicity in 156 patients yielded a high incidence of toxic reaction (62%), necessitating discontinuation of the drug therapy in 36% of the patients." | 1.26 | Toxicity of penicillamine. A serious limitation to therapy in rheumatoid arthritis. ( Bernhard, GC; Goldman, AL; Halverson, PB; Kozin, F, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (79.31) | 18.7374 |
| 1990's | 2 (6.90) | 18.2507 |
| 2000's | 3 (10.34) | 29.6817 |
| 2010's | 1 (3.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blythin, DJ | 1 |
| Kaminski, JJ | 1 |
| Domalski, MS | 1 |
| Spitler, J | 1 |
| Solomon, DM | 1 |
| Conn, DJ | 1 |
| Wong, SC | 1 |
| Verbiar, LL | 1 |
| Bober, LA | 1 |
| Chiu, PJ | 1 |
| Wiernicka, A | 1 |
| Jańczyk, W | 1 |
| Dądalski, M | 1 |
| Avsar, Y | 1 |
| Schmidt, H | 1 |
| Socha, P | 1 |
| Jiang, L | 1 |
| Zhao, N | 1 |
| Ni, L | 1 |
| Saar, P | 1 |
| Müller-Ladner, U | 1 |
| Kean, WF | 2 |
| Anastassiades, TP | 1 |
| Dwosh, IL | 1 |
| Ford, PM | 1 |
| Kelly, WG | 1 |
| Dok, CM | 1 |
| Cohen, S | 1 |
| Runge, LA | 1 |
| Lynggaard, F | 1 |
| Mohammed, SH | 1 |
| Schulze, S | 1 |
| Ammitzbøll, T | 3 |
| Stein, HB | 1 |
| Patterson, AC | 1 |
| Offer, RC | 1 |
| Atkins, CJ | 1 |
| Teufel, A | 1 |
| Robinson, HS | 1 |
| Pope, JE | 1 |
| Balint, GA | 1 |
| Stummvoll, GH | 1 |
| Colombo, B | 1 |
| Gerloni, V | 1 |
| Hill, HF | 1 |
| Halverson, PB | 1 |
| Kozin, F | 1 |
| Bernhard, GC | 1 |
| Goldman, AL | 1 |
| Rangachari, PK | 1 |
| Muirden, KD | 1 |
| Kay, A | 1 |
| Magnus, JH | 1 |
| Gran, JT | 1 |
| Mikkelsen, K | 1 |
| Nygaard, H | 1 |
| Brath, HK | 1 |
| Manthorpe, R | 1 |
| Tvede, N | 1 |
| Bendixen, G | 1 |
| Hendel, L | 2 |
| Kreuzig, F | 2 |
| Asboe-Hansen, G | 2 |
| Worning, H | 1 |
| Cuthbert, MF | 1 |
| Wallnöfer, H | 1 |
| Hanusch, M | 1 |
| Gordon, MH | 1 |
| Ehrlich, GE | 1 |
| Haley, TJ | 1 |
| Golding, JR | 1 |
| Wilson, JV | 1 |
| Day, AT | 1 |
7 reviews available for penicillamine and Cholera Infantum
| Article | Year |
|---|---|
Treatment of systemic sclerosis.
Topics: Antirheumatic Agents; Calcinosis; Clinical Trials as Topic; Gastrointestinal Diseases; Heart Disease | 1996 |
Current treatment options in systemic Sclerosis (Scleroderma).
Topics: Antirheumatic Agents; Gastrointestinal Diseases; Hematopoietic Stem Cell Transplantation; Humans; Hy | 2002 |
[Penicillamine: its use in rheumatoid arthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Drug Eruptions; Drug Evaluation; Female; Fever; Gastrointestinal | 1979 |
Gold and D-penicillamine and the gastrointestinal tract.
Topics: Chemical Phenomena; Chemistry; Gastrointestinal Diseases; Gold; Humans; Penicillamine | 1989 |
The use of chloroquine and D-penicillamine in the treatment of rheumatoid arthritis.
Topics: Anti-Glomerular Basement Membrane Disease; Arthritis, Rheumatoid; Captopril; Chloroquine; Clinical T | 1986 |
Continuing the copper saga.
Topics: Adult; Animals; Brain Diseases; Copper; Diet; Female; Gastrointestinal Diseases; Hepatolenticular De | 1970 |
Saturnism, pediatric and adult lead poisoning.
Topics: Adult; Central Nervous System Diseases; Chicago; Child; Child, Preschool; Edetic Acid; Environmental | 1971 |
5 trials available for penicillamine and Cholera Infantum
| Article | Year |
|---|---|
Treatment of rheumatoid arthritis with penicillamine.
Topics: Arthritis, Rheumatoid; Azathioprine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Dru | 1977 |
The use of chloroquine and D-penicillamine in the treatment of rheumatoid arthritis.
Topics: Anti-Glomerular Basement Membrane Disease; Arthritis, Rheumatoid; Captopril; Chloroquine; Clinical T | 1986 |
Toxicity of longterm low dose D-penicillamine therapy in rheumatoid arthritis. Cooperative Systematic Studies of Rheumatic Disease Group.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Drug | 1987 |
[Treatment of chronic hepatitis with immunosuppressive agents and D-penicillamine].
Topics: Agranulocytosis; Azathioprine; Chronic Disease; Clinical Trials as Topic; Drug Hypersensitivity; Fem | 1973 |
Penicillamine for treatment of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Blood Sedimentation; Clinical Trials as Topic; Copper; Drug Evaluation; Gastr | 1974 |
18 other studies available for penicillamine and Cholera Infantum
| Article | Year |
|---|---|
Antiinflammatory activity of substituted 6-hydroxypyrimido[2,1-f]purine-2,4,8(1H,3H,9H)-triones. Atypical nonsteroidal antiinflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Biological Availability; Cyclooxygenase Inhibitors; Ga | 1986 |
Gastrointestinal side effects in children with Wilson's disease treated with zinc sulphate.
Topics: Adenosine Triphosphatases; Adolescent; Cation Transport Proteins; Child; Child, Preschool; Copper-Tr | 2013 |
[Retrospective study of adverse events in patients with rheumatoid arthritis treated with second-line drugs].
Topics: Adult; Anorexia; Antirheumatic Agents; Arthritis, Rheumatoid; Exanthema; Female; Gastrointestinal Di | 2002 |
[Systemic sclerosis--a challenge in rheumatology].
Topics: Antibodies, Antinuclear; Gastrointestinal Diseases; Humans; Hypertension, Pulmonary; Immunosuppressi | 2006 |
Efficacy and toxicity of D-penicillamine for rheumatoid disease in the elderly.
Topics: Adult; Age Factors; Aged; Arthritis, Rheumatoid; Drug Eruptions; Female; Gastrointestinal Diseases; | 1982 |
The gastrointestinal manifestations of scleroderma: pathogenesis and management.
Topics: Action Potentials; Diagnosis, Differential; Digestive System; Gastrointestinal Diseases; Gastrointes | 1980 |
Risk/benefit analysis of hydroxychloroquine sulfate treatment in rheumatoid arthritis.
Topics: Actuarial Analysis; Arthritis, Rheumatoid; Gastrointestinal Diseases; Gold; Humans; Hydroxychloroqui | 1983 |
[Progressive systemic sclerosis with gastrointestinal manifestations].
Topics: Adult; Gastrointestinal Diseases; Glutamine; Humans; Male; Penicillamine; Scleroderma, Systemic | 1982 |
Adverse effects of D-penicillamine in rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Drug Administration Schedule; Gastrointestinal Disea | 1980 |
A novel approach to reduce the unwanted gastric side-effects of orally administered non-steroidal anti-inflammatory drugs in rats.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cysteine; Drug Therapy, Comb | 1997 |
Toxicity of penicillamine. A serious limitation to therapy in rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Female; Gastrointestinal Diseases; H | 1978 |
European League against Rheumatism study of adverse reactions to D-penicillamine.
Topics: Aged; Arthritis, Rheumatoid; Drug Eruptions; Europe; Female; Gastrointestinal Diseases; Hematologic | 1986 |
Toxicity to D-penicillamine in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Drug Eruptions; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; | 1987 |
Auranofin in rheumatoid arthritis: use in patients with side-effects or lack of effect to gold sodium thiomalate or gold thioglucose and/or D-penicillamine. A prospective one year investigation.
Topics: Arthritis, Rheumatoid; Auranofin; Aurothioglucose; Drug Resistance; Female; Gastrointestinal Disease | 1988 |
Bioavailability of D-penicillamine in relation to gastrointestinal involvement of generalized scleroderma.
Topics: Administration, Oral; Adult; Aged; Biological Availability; Capsules; Esophageal Diseases; Female; G | 1987 |
Bioavailability of D-penicillamine in a patient with gastrointestinal progressive systemic sclerosis.
Topics: Administration, Oral; Adult; Biological Availability; Enema; Fats; Feces; Gastrointestinal Diseases; | 1986 |
Adverse reactions to non-steroidal antirheumatic drugs.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Benzophenones; Chemical and Drug Induced Liv | 1974 |
Observations on the treatment of rheumatoid disease with penicillamine.
Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Sedimentation; Female; Gastrointestinal Diseases; Humans; | 1970 |