penicillamine has been researched along with Cholangitis, Sclerosing in 7 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
Cholangitis, Sclerosing: Chronic inflammatory disease of the BILIARY TRACT. It is characterized by fibrosis and hardening of the intrahepatic and extrahepatic biliary ductal systems leading to bile duct strictures, CHOLESTASIS, and eventual BILIARY CIRRHOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cholangiocarcinoma complicating primary sclerosing cholangitis often was detected at an advanced tumor stage, which precluded effective therapy, and overall median survival was 5 months." | 2.67 | Cholangiocarcinoma complicating primary sclerosing cholangitis. ( Coffey, RJ; LaRusso, NF; Nagorney, DM; Rosen, CB; Wiesner, RH, 1991) |
| "Primary sclerosing cholangitis is a cholestatic disease." | 2.43 | D-penicillamine for primary sclerosing cholangitis. ( Chen, W; Klingenberg, SL, 2006) |
| "Primary sclerosing cholangitis is a chronic cholestatic liver disease characterized by a progressive, obliterating fibrosis of the intrahepatic and extrahepatic bile ducts." | 2.40 | The management of primary sclerosing cholangitis. ( Chapman, RW; Mitchell, SA, 1998) |
| "Primary sclerosing cholangitis is a generally progressive, sometimes fatal, chronic hepatobiliary disorder for which no effective medical or surgical therapy now exists." | 2.40 | The Fifth Carlos E. Rubio Memorial Lecture. Sclerosing cholangitis: pathogenesis, pathology, and practice. ( Larusso, NF, 1999) |
| "The diagnosis of primary sclerosing cholangitis (PSC) is based on the characteristic cholangiographic manifestations of the condition." | 2.38 | Surgical pathology of the syndrome of primary sclerosing cholangitis. ( Ludwig, J, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 5 (71.43) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mitchell, SA | 1 |
| Chapman, RW | 1 |
| Klingenberg, SL | 1 |
| Chen, W | 1 |
| Larusso, NF | 3 |
| Angulo, P | 1 |
| Larson, DR | 1 |
| Therneau, TM | 1 |
| Batts, KP | 1 |
| Lindor, KD | 1 |
| Rosen, CB | 1 |
| Nagorney, DM | 1 |
| Wiesner, RH | 1 |
| Coffey, RJ | 1 |
| Kaplan, MM | 1 |
| Ludwig, J | 1 |
5 reviews available for penicillamine and Cholangitis, Sclerosing
| Article | Year |
|---|---|
The management of primary sclerosing cholangitis.
Topics: Adrenal Cortex Hormones; Cholangitis, Sclerosing; Cholestasis; Humans; Immunosuppressive Agents; Met | 1998 |
D-penicillamine for primary sclerosing cholangitis.
Topics: Cholangitis, Sclerosing; Humans; Penicillamine; Randomized Controlled Trials as Topic | 2006 |
The Fifth Carlos E. Rubio Memorial Lecture. Sclerosing cholangitis: pathogenesis, pathology, and practice.
Topics: Adrenal Cortex Hormones; Adult; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biopsy; Chelating Age | 1999 |
Medical approaches to primary sclerosing cholangitis.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antipruritics; Azathioprine; Cholangitis, Sclerosing | 1991 |
Surgical pathology of the syndrome of primary sclerosing cholangitis.
Topics: Biopsy; Cholangitis, Sclerosing; Gallbladder; Humans; Liver; Liver Diseases; Liver Transplantation; | 1989 |
1 trial available for penicillamine and Cholangitis, Sclerosing
| Article | Year |
|---|---|
Cholangiocarcinoma complicating primary sclerosing cholangitis.
Topics: Adenoma, Bile Duct; Adult; Bile Duct Neoplasms; Cholangitis, Sclerosing; Combined Modality Therapy; | 1991 |
1 other study available for penicillamine and Cholangitis, Sclerosing
| Article | Year |
|---|---|
Time course of histological progression in primary sclerosing cholangitis.
Topics: Adolescent; Adult; Aged; Biopsy; Cholagogues and Choleretics; Cholangitis, Sclerosing; Disease Progr | 1999 |