penicillamine has been researched along with Cardiomegaly in 5 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "SOP." | 1.30 | Nitric oxide inhibits isoprenaline-induced positive inotropic effects in normal, but not in hypertrophied rat heart. ( Brodde, OE; Heinroth-Hoffmann, I; Kotchi Kotchi, E; Osten, B; Preiss, M; Röhnert, P; Weisselberg, T, 1998) |
| "A case of severe diffuse systemic sclerosis with cardiomegaly and cardiac failure is described." | 1.26 | Treatment of scleroderma heart by D-penicillamine. ( Muers, M; Stokes, W, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kojda, G | 1 |
| Kottenberg, K | 1 |
| Stasch, JP | 1 |
| Schrör, K | 1 |
| Noack, E | 1 |
| Kotchi Kotchi, E | 1 |
| Weisselberg, T | 1 |
| Röhnert, P | 1 |
| Preiss, M | 1 |
| Heinroth-Hoffmann, I | 1 |
| Osten, B | 1 |
| Brodde, OE | 1 |
| Bryant, SM | 1 |
| Sears, CE | 1 |
| Rigg, L | 1 |
| Terrar, DA | 1 |
| Casadei, B | 1 |
| Muers, M | 1 |
| Stokes, W | 1 |
| Will, JA | 1 |
| Kay, JM | 1 |
5 other studies available for penicillamine and Cardiomegaly
| Article | Year |
|---|---|
Positive inotropic effect of exogenous and endogenous NO in hypertrophic rat hearts.
Topics: Animals; Blood Pressure; Cardiomegaly; Heart; Heart Rate; Hypertension; In Vitro Techniques; Male; M | 1997 |
Nitric oxide inhibits isoprenaline-induced positive inotropic effects in normal, but not in hypertrophied rat heart.
Topics: Adrenergic beta-Agonists; Animals; Aorta, Abdominal; Cardiomegaly; Cardiotonic Agents; Heart Ventric | 1998 |
Nitric oxide does not modulate the hyperpolarization-activated current, I(f), in ventricular myocytes from spontaneously hypertensive rats.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Amphotericin B; Analysis of Variance; Animals; Arrhythm | 2001 |
Treatment of scleroderma heart by D-penicillamine.
Topics: Adult; Cardiomegaly; Cardiomyopathies; Exercise Test; Female; Heart Failure; Humans; Penicillamine; | 1976 |
Hypertensive pulmonary vascular disease associated with papain emphysema in rats.
Topics: Aerosols; Animals; Cardiomegaly; Drug Synergism; Female; Heart; Hypertension, Pulmonary; Hypoxia; Lu | 1974 |