Page last updated: 2024-11-07

penicillamine and Cardiac Hypertrophy

penicillamine has been researched along with Cardiac Hypertrophy in 5 studies

Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.

Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.

Research Excerpts

ExcerptRelevanceReference
"SOP."1.30Nitric oxide inhibits isoprenaline-induced positive inotropic effects in normal, but not in hypertrophied rat heart. ( Brodde, OE; Heinroth-Hoffmann, I; Kotchi Kotchi, E; Osten, B; Preiss, M; Röhnert, P; Weisselberg, T, 1998)
"A case of severe diffuse systemic sclerosis with cardiomegaly and cardiac failure is described."1.26Treatment of scleroderma heart by D-penicillamine. ( Muers, M; Stokes, W, 1976)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kojda, G1
Kottenberg, K1
Stasch, JP1
Schrör, K1
Noack, E1
Kotchi Kotchi, E1
Weisselberg, T1
Röhnert, P1
Preiss, M1
Heinroth-Hoffmann, I1
Osten, B1
Brodde, OE1
Bryant, SM1
Sears, CE1
Rigg, L1
Terrar, DA1
Casadei, B1
Muers, M1
Stokes, W1
Will, JA1
Kay, JM1

Other Studies

5 other studies available for penicillamine and Cardiac Hypertrophy

ArticleYear
Positive inotropic effect of exogenous and endogenous NO in hypertrophic rat hearts.
    British journal of pharmacology, 1997, Volume: 122, Issue:5

    Topics: Animals; Blood Pressure; Cardiomegaly; Heart; Heart Rate; Hypertension; In Vitro Techniques; Male; M

1997
Nitric oxide inhibits isoprenaline-induced positive inotropic effects in normal, but not in hypertrophied rat heart.
    Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:5

    Topics: Adrenergic beta-Agonists; Animals; Aorta, Abdominal; Cardiomegaly; Cardiotonic Agents; Heart Ventric

1998
Nitric oxide does not modulate the hyperpolarization-activated current, I(f), in ventricular myocytes from spontaneously hypertensive rats.
    Cardiovascular research, 2001, Volume: 51, Issue:1

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Amphotericin B; Analysis of Variance; Animals; Arrhythm

2001
Treatment of scleroderma heart by D-penicillamine.
    British heart journal, 1976, Volume: 38, Issue:8

    Topics: Adult; Cardiomegaly; Cardiomyopathies; Exercise Test; Female; Heart Failure; Humans; Penicillamine;

1976
Hypertensive pulmonary vascular disease associated with papain emphysema in rats.
    Respiration; international review of thoracic diseases, 1974, Volume: 31, Issue:3

    Topics: Aerosols; Animals; Cardiomegaly; Drug Synergism; Female; Heart; Hypertension, Pulmonary; Hypoxia; Lu

1974