penicillamine has been researched along with Cancer of Liver in 17 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study we investigated whether long-term administration of D-penicillamine could also prevent chronic hepatitis and subsequent hepatocellular carcinoma in Long-Evans Cinnamon rats." | 5.29 | Prevention of spontaneous hepatocellular carcinoma in Long-Evans cinnamon rats with hereditary hepatitis by the administration of D-penicillamine. ( Hosokawa, M; Jong-Hon, K; Kasai, H; Takeichi, N; Togashi, Y, 1993) |
| "Certain features of Wilson's disease (WD) in Asia have been found to be different from those in other continents." | 2.38 | Geographic variations in Wilson's disease. ( Chu, NS; Hung, TP, 1993) |
| "Hepatocellular carcinoma has rarely been reported in Wilson's disease, particularly in women." | 2.38 | Hepatocellular carcinoma in a case of Wilson's disease. ( Cheng, WS; Govindarajan, S; Redeker, AG, 1992) |
| "Wilson disease is a rare genetic disorder of copper metabolism with a wide range of clinical presentations." | 1.56 | Wilson disease: 30-year data on epidemiology, clinical presentation, treatment modalities and disease outcomes from two tertiary Greek centers. ( Dalekos, GN; Deutsch, M; Gabeta, S; Gatselis, NK; Koskinas, J; Koullias, E; Manesis, E; Saitis, A; Savvanis, S; Tampaki, M, 2020) |
| "The most common Wilson disease (WD) mutations p." | 1.43 | Functional analysis and drug response to zinc and D-penicillamine in stable ATP7B mutant hepatic cell lines. ( Aggarwal, A; Bhatt, M; Chandhok, G; Horvath, J; Schmidt, HH; Zibert, A, 2016) |
| " In this study we investigated whether long-term administration of D-penicillamine could also prevent chronic hepatitis and subsequent hepatocellular carcinoma in Long-Evans Cinnamon rats." | 1.29 | Prevention of spontaneous hepatocellular carcinoma in Long-Evans cinnamon rats with hereditary hepatitis by the administration of D-penicillamine. ( Hosokawa, M; Jong-Hon, K; Kasai, H; Takeichi, N; Togashi, Y, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.76) | 18.7374 |
| 1990's | 7 (41.18) | 18.2507 |
| 2000's | 2 (11.76) | 29.6817 |
| 2010's | 5 (29.41) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Tampaki, M | 1 |
| Gatselis, NK | 1 |
| Savvanis, S | 1 |
| Koullias, E | 1 |
| Saitis, A | 1 |
| Gabeta, S | 1 |
| Deutsch, M | 1 |
| Manesis, E | 1 |
| Dalekos, GN | 1 |
| Koskinas, J | 1 |
| Bersier, M | 1 |
| Pache, I | 1 |
| Chandhok, G | 2 |
| Schmitt, N | 1 |
| Sauer, V | 1 |
| Aggarwal, A | 2 |
| Bhatt, M | 2 |
| Schmidt, HH | 2 |
| Horvath, J | 1 |
| Zibert, A | 1 |
| Marquez-Quiñones, A | 1 |
| Cipak, A | 1 |
| Zarkovic, K | 1 |
| Fattel-Fazenda, S | 1 |
| Villa-Treviño, S | 1 |
| Waeg, G | 1 |
| Zarkovic, N | 1 |
| Guéraud, F | 1 |
| Lowette, KF | 1 |
| Desmet, K | 1 |
| Witters, P | 1 |
| Laleman, W | 1 |
| Verslype, C | 1 |
| Nevens, F | 1 |
| Fevery, J | 1 |
| Cassiman, DM | 1 |
| Jiang, JL | 2 |
| Yao, XY | 1 |
| Zhou, J | 1 |
| Huang, Y | 1 |
| Chen, ZN | 2 |
| Sternlieb, I | 1 |
| Ioannidis, I | 1 |
| de Groot, H | 1 |
| Jong-Hon, K | 1 |
| Togashi, Y | 1 |
| Kasai, H | 1 |
| Hosokawa, M | 1 |
| Takeichi, N | 1 |
| Chu, NS | 1 |
| Hung, TP | 1 |
| Schobersberger, W | 1 |
| Hoffmann, G | 1 |
| Fandrey, J | 1 |
| Calmels, S | 1 |
| Hainaut, P | 1 |
| Ohshima, H | 1 |
| Barisani, D | 1 |
| Cairo, G | 1 |
| Ginelli, E | 1 |
| Marozzi, A | 1 |
| Conte, D | 1 |
| Zhou, Q | 1 |
| Yu, MK | 1 |
| Ho, LS | 1 |
| Chan, HC | 1 |
| Cheng, WS | 1 |
| Govindarajan, S | 1 |
| Redeker, AG | 1 |
| Markoff, N | 1 |
4 reviews available for penicillamine and Cancer of Liver
| Article | Year |
|---|---|
Copper and the liver.
Topics: Acute Disease; Adult; Age Factors; Animals; Bufo marinus; Carcinoma, Hepatocellular; Chemical and Dr | 1980 |
Geographic variations in Wilson's disease.
Topics: Adolescent; Adult; Brain Diseases, Metabolic; Carcinoma, Hepatocellular; China; Comorbidity; Consang | 1993 |
Hepatocellular carcinoma in a case of Wilson's disease.
Topics: Adult; Carcinoma, Hepatocellular; Female; Hepatolenticular Degeneration; Humans; Liver; Liver Neopla | 1992 |
[Long-term therapy of liver diseases].
Topics: Aged; Anabolic Agents; Chronic Disease; Cortisone; Diet Therapy; Fatty Liver; Female; Fluorouracil; | 1972 |
13 other studies available for penicillamine and Cancer of Liver
| Article | Year |
|---|---|
Wilson disease: 30-year data on epidemiology, clinical presentation, treatment modalities and disease outcomes from two tertiary Greek centers.
Topics: Adult; Aged; Carcinoma, Hepatocellular; Greece; Hepatolenticular Degeneration; Humans; Liver Neoplas | 2020 |
[Wilson's disease: programed wandering?].
Topics: Adenosine Triphosphatases; Administration, Oral; Adult; Biomarkers; Carcinoma, Hepatocellular; Catio | 2013 |
The effect of zinc and D-penicillamine in a stable human hepatoma ATP7B knockout cell line.
Topics: Adenosine Triphosphatases; Cation Transport Proteins; Cell Survival; Copper; Copper-Transporting ATP | 2014 |
Functional analysis and drug response to zinc and D-penicillamine in stable ATP7B mutant hepatic cell lines.
Topics: Adenosine Triphosphatases; Apoptosis; Carcinoma, Hepatocellular; Cation Transport Proteins; Cell Sur | 2016 |
HNE-protein adducts formation in different pre-carcinogenic stages of hepatitis in LEC rats.
Topics: Acute Disease; Aldehydes; Animals; Disease Models, Animal; Hepatitis B; Lipid Peroxidation; Liver Ne | 2010 |
Wilson's disease: long-term follow-up of a cohort of 24 patients treated with D-penicillamine.
Topics: Adolescent; Adult; Alanine Transaminase; Aspartate Aminotransferases; Carcinoma, Hepatocellular; Che | 2010 |
[Effect of Ca2+ mobilization on release and activation of matrix metalloproteinases in hepatocellular carcinoma cells].
Topics: Calcium; Carcinoma, Hepatocellular; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Live | 2004 |
Cytotoxicity of nitric oxide in Fu5 rat hepatoma cells: evidence for co-operative action with hydrogen peroxide.
Topics: Animals; Carcinoma, Hepatocellular; Catalase; Cell Line; Cell Survival; Glucose Oxidase; Hydrogen Pe | 1993 |
Prevention of spontaneous hepatocellular carcinoma in Long-Evans cinnamon rats with hereditary hepatitis by the administration of D-penicillamine.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Alanine Transaminase; Animals; Anticarcinogenic Agents; Aspartate Amino | 1993 |
Nitric oxide donors suppress erythropoietin production in vitro.
Topics: Carcinoma, Hepatocellular; Cyclic GMP; Cytokines; Erythropoietin; Humans; Hydrogen Peroxide; Liver N | 1996 |
Nitric oxide induces conformational and functional modifications of wild-type p53 tumor suppressor protein.
Topics: Breast Neoplasms; Carcinoma, Hepatocellular; DNA, Neoplasm; Glutathione; Humans; Liver Neoplasms; Ni | 1997 |
Nitric oxide reduces nontransferrin-bound iron transport in HepG2 cells.
Topics: Apoptosis; Biological Transport; Carcinoma, Hepatocellular; Ferric Compounds; Ferritins; Ferrous Com | 1999 |
The involvement of HAb18G/CD147 in regulation of store-operated calcium entry and metastasis of human hepatoma cells.
Topics: Alkaloids; Antigens, CD; Antigens, Neoplasm; Antigens, Surface; Avian Proteins; Basigin; Blood Prote | 2001 |