penicillamine has been researched along with Bone Loss, Osteoclastic in 7 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "IFN had no effect on bone resorption and little effect on NO production when used alone or in combination with calciotropic hormones, however, suggesting that IFN selectively inhibits cytokine-induced bone resorption by generating large amounts of NO." | 1.29 | Nitric oxide: a cytokine-induced regulator of bone resorption. ( Benjamin, N; Grabowski, PS; Helfrich, MH; Ho, LP; Johnston, PW; Ralston, SH, 1995) |
| " Dose-response curves showed that Aur was at least 10 times more potent than GST." | 1.27 | Comparison of the effects of auranofin, gold sodium thiomalate, and penicillamine on resorption of cultured fetal rat long bones. ( Hurley, MM; Jones, TG; Raisz, LG; Vargas, SJ, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Trang, LE | 1 |
| Ralston, SH | 2 |
| Ho, LP | 1 |
| Helfrich, MH | 1 |
| Grabowski, PS | 1 |
| Johnston, PW | 1 |
| Benjamin, N | 1 |
| Holliday, LS | 1 |
| Dean, AD | 1 |
| Lin, RH | 1 |
| Greenwald, JE | 1 |
| Gluck, SL | 1 |
| van't Hof, RJ | 1 |
| Armour, KJ | 1 |
| Smith, LM | 1 |
| Armour, KE | 1 |
| Wei, XQ | 1 |
| Liew, FY | 1 |
| Vargas, SJ | 1 |
| Jones, TG | 1 |
| Hurley, MM | 1 |
| Raisz, LG | 1 |
| Reid, DM | 1 |
| Kennedy, NS | 1 |
| Smith, MA | 1 |
| Nicoll, J | 1 |
| Brown, N | 1 |
| Tothill, P | 1 |
| Nuki, G | 1 |
| Riede, UN | 1 |
2 reviews available for penicillamine and Bone Loss, Osteoclastic
| Article | Year |
|---|---|
Prostaglandins and inflammation.
Topics: Animals; Anti-Inflammatory Agents; Antibody Formation; Arthritis, Rheumatoid; Blood Coagulation; Bon | 1980 |
Experimental aspects of growth plate disorders. A study concerning chondrocytic lysosomes in different physical and metabolic conditions.
Topics: Animals; Bone Diseases; Bone Matrix; Bone Regeneration; Bone Resorption; Carotenoids; Cartilage; Dim | 1974 |
5 other studies available for penicillamine and Bone Loss, Osteoclastic
| Article | Year |
|---|---|
Nitric oxide: a cytokine-induced regulator of bone resorption.
Topics: Animals; Arginine; Base Sequence; Bone Resorption; Calcium; Cytokines; Dinoprostone; DNA Primers; Dr | 1995 |
Low NO concentrations inhibit osteoclast formation in mouse marrow cultures by cGMP-dependent mechanism.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bone Marrow Cells; Bone Resorption; Bucladesine; Ca | 1997 |
Requirement of the inducible nitric oxide synthase pathway for IL-1-induced osteoclastic bone resorption.
Topics: Animals; Bone Marrow Cells; Bone Resorption; Cell Differentiation; Coculture Techniques; Immunoenzym | 2000 |
Comparison of the effects of auranofin, gold sodium thiomalate, and penicillamine on resorption of cultured fetal rat long bones.
Topics: Animals; Auranofin; Bone and Bones; Bone Resorption; Cells, Cultured; Dinoprostone; Dose-Response Re | 1987 |
Bone loss in rheumatoid arthritis and primary generalized osteoarthrosis: effects of corticosteroids, suppressive antirheumatic drugs and calcium supplements.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Bone Resorption; Calcium; | 1986 |