penicillamine has been researched along with Bleeding in 9 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Penicillamine is the drug of choice in Wilson's disease and a therapeutic alternative in rheumatoid arthritis." | 5.27 | Penicillamine associated pulmonary hemorrhage. ( Cross, CE; Gamble, CN; Louie, S, 1986) |
| "We report the case of a 34-year-old white woman with a history of progressive systemic scleroderma (PSS) and diffuse alveolar hemorrhage (DAH) that may be either a rare complication of PSS or induced by D-penicillamine." | 4.80 | A case study and national database report of progressive systemic sclerosis and associated conditions. ( Mannino, D; Phillips, B; Phillips, D, 1998) |
| "D-penicillamine has been reported to cause antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis presenting as rapidly progressive glomerulonephritis or pulmonary-renal syndrome mostly in adults." | 3.91 | A Pediatric Case of a D-Penicillamine Induced ANCA-associated Vasculitis Manifesting a Pulmonary-Renal Syndrome. ( Cheong, HI; Cho, MH; Ha, IS; Hyun, H; Kang, HG; Kang, S; Kim, JH; Kim, WS; Ko, JS; Moon, KC, 2019) |
| "Fatal pulmonary hemorrhages and rapidly progressive glomerulonephritis occurred in three patients with Wilson's disease (hepatolenticular degeneration) who had been treated with penicillamine for 2 to 31/2 years." | 3.65 | D-penicillamine induced Goodpasture's syndrome in Wilson's disease. ( Bennett, B; Scheinberg, IH; Sternlieb, I, 1975) |
| "Penicillamine is the drug of choice in Wilson's disease and a therapeutic alternative in rheumatoid arthritis." | 1.27 | Penicillamine associated pulmonary hemorrhage. ( Cross, CE; Gamble, CN; Louie, S, 1986) |
| "Moderate thrombocytopenia was observed in three of the five bleeders and in two of the others." | 1.26 | Platelet function and coagulation in patients with Wilson disease. ( Bowie, JW; Goldstein, NP; Owen, CA, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kang, S | 1 |
| Cho, MH | 1 |
| Hyun, H | 1 |
| Kim, JH | 1 |
| Ko, JS | 1 |
| Kang, HG | 1 |
| Cheong, HI | 1 |
| Kim, WS | 1 |
| Moon, KC | 1 |
| Ha, IS | 1 |
| Derk, CT | 1 |
| Jimenez, SA | 1 |
| Hashimoto, K | 1 |
| McEvoy, B | 1 |
| Belcher, R | 1 |
| Harbrecht, BG | 1 |
| Wu, B | 1 |
| Watkins, SC | 1 |
| Billiar, TR | 1 |
| Peitzman, AB | 1 |
| Phillips, D | 1 |
| Phillips, B | 1 |
| Mannino, D | 1 |
| Sternlieb, I | 1 |
| Bennett, B | 1 |
| Scheinberg, IH | 1 |
| Owen, CA | 1 |
| Goldstein, NP | 1 |
| Bowie, JW | 1 |
| Louie, S | 1 |
| Gamble, CN | 1 |
| Cross, CE | 1 |
| Afifi, AM | 1 |
| Tawfeek, S | 1 |
1 review available for penicillamine and Bleeding
| Article | Year |
|---|---|
A case study and national database report of progressive systemic sclerosis and associated conditions.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Cause of Deat | 1998 |
8 other studies available for penicillamine and Bleeding
| Article | Year |
|---|---|
A Pediatric Case of a D-Penicillamine Induced ANCA-associated Vasculitis Manifesting a Pulmonary-Renal Syndrome.
Topics: Adolescent; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Female; Glomerulonephritis; | 2019 |
Goodpasture-like syndrome induced by D-penicillamine in a patient with systemic sclerosis: report and review of the literature.
Topics: Aged; Anti-Glomerular Basement Membrane Disease; Antirheumatic Agents; Fatal Outcome; Glomerulonephr | 2003 |
Ultrastructure of penicillamine-induced skin lesions.
Topics: Adult; Collagen; Drug Eruptions; Elastic Tissue; Epidermis; Fibroblasts; Hemorrhage; Humans; Male; M | 1981 |
Inhibition of nitric oxide synthesis during severe shock but not after resuscitation increases hepatic injury and neutrophil accumulation in hemorrhaged rats.
Topics: Alanine Transaminase; Animals; Antirheumatic Agents; Aspartate Aminotransferases; Endothelium; Enzym | 1997 |
D-penicillamine induced Goodpasture's syndrome in Wilson's disease.
Topics: Adult; Anti-Glomerular Basement Membrane Disease; Child; Female; Fluorescent Antibody Technique; Glo | 1975 |
Platelet function and coagulation in patients with Wilson disease.
Topics: Adolescent; Adult; Blood Coagulation; Blood Platelets; Child; Female; Hemorrhage; Hepatolenticular D | 1976 |
Penicillamine associated pulmonary hemorrhage.
Topics: Adult; Antigen-Antibody Complex; Hemorrhage; Hepatolenticular Degeneration; Humans; Lung Diseases; M | 1986 |
Deafness due to Waldenstrom macroglobulinaemia.
Topics: Audiometry; Blood Coagulation Disorders; Blood Coagulation Tests; Blood Proteins; Chlorambucil; Deaf | 1971 |