Page last updated: 2024-11-07

penicillamine and Bleeding

penicillamine has been researched along with Bleeding in 9 studies

Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.

Research Excerpts

ExcerptRelevanceReference
"Penicillamine is the drug of choice in Wilson's disease and a therapeutic alternative in rheumatoid arthritis."5.27Penicillamine associated pulmonary hemorrhage. ( Cross, CE; Gamble, CN; Louie, S, 1986)
"We report the case of a 34-year-old white woman with a history of progressive systemic scleroderma (PSS) and diffuse alveolar hemorrhage (DAH) that may be either a rare complication of PSS or induced by D-penicillamine."4.80A case study and national database report of progressive systemic sclerosis and associated conditions. ( Mannino, D; Phillips, B; Phillips, D, 1998)
"D-penicillamine has been reported to cause antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis presenting as rapidly progressive glomerulonephritis or pulmonary-renal syndrome mostly in adults."3.91A Pediatric Case of a D-Penicillamine Induced ANCA-associated Vasculitis Manifesting a Pulmonary-Renal Syndrome. ( Cheong, HI; Cho, MH; Ha, IS; Hyun, H; Kang, HG; Kang, S; Kim, JH; Kim, WS; Ko, JS; Moon, KC, 2019)
"Fatal pulmonary hemorrhages and rapidly progressive glomerulonephritis occurred in three patients with Wilson's disease (hepatolenticular degeneration) who had been treated with penicillamine for 2 to 31/2 years."3.65D-penicillamine induced Goodpasture's syndrome in Wilson's disease. ( Bennett, B; Scheinberg, IH; Sternlieb, I, 1975)
"Penicillamine is the drug of choice in Wilson's disease and a therapeutic alternative in rheumatoid arthritis."1.27Penicillamine associated pulmonary hemorrhage. ( Cross, CE; Gamble, CN; Louie, S, 1986)
"Moderate thrombocytopenia was observed in three of the five bleeders and in two of the others."1.26Platelet function and coagulation in patients with Wilson disease. ( Bowie, JW; Goldstein, NP; Owen, CA, 1976)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19905 (55.56)18.7374
1990's2 (22.22)18.2507
2000's1 (11.11)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kang, S1
Cho, MH1
Hyun, H1
Kim, JH1
Ko, JS1
Kang, HG1
Cheong, HI1
Kim, WS1
Moon, KC1
Ha, IS1
Derk, CT1
Jimenez, SA1
Hashimoto, K1
McEvoy, B1
Belcher, R1
Harbrecht, BG1
Wu, B1
Watkins, SC1
Billiar, TR1
Peitzman, AB1
Phillips, D1
Phillips, B1
Mannino, D1
Sternlieb, I1
Bennett, B1
Scheinberg, IH1
Owen, CA1
Goldstein, NP1
Bowie, JW1
Louie, S1
Gamble, CN1
Cross, CE1
Afifi, AM1
Tawfeek, S1

Reviews

1 review available for penicillamine and Bleeding

ArticleYear
A case study and national database report of progressive systemic sclerosis and associated conditions.
    Journal of women's health, 1998, Volume: 7, Issue:9

    Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Cause of Deat

1998

Other Studies

8 other studies available for penicillamine and Bleeding

ArticleYear
A Pediatric Case of a D-Penicillamine Induced ANCA-associated Vasculitis Manifesting a Pulmonary-Renal Syndrome.
    Journal of Korean medical science, 2019, Jun-24, Volume: 34, Issue:24

    Topics: Adolescent; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Female; Glomerulonephritis;

2019
Goodpasture-like syndrome induced by D-penicillamine in a patient with systemic sclerosis: report and review of the literature.
    The Journal of rheumatology, 2003, Volume: 30, Issue:7

    Topics: Aged; Anti-Glomerular Basement Membrane Disease; Antirheumatic Agents; Fatal Outcome; Glomerulonephr

2003
Ultrastructure of penicillamine-induced skin lesions.
    Journal of the American Academy of Dermatology, 1981, Volume: 4, Issue:3

    Topics: Adult; Collagen; Drug Eruptions; Elastic Tissue; Epidermis; Fibroblasts; Hemorrhage; Humans; Male; M

1981
Inhibition of nitric oxide synthesis during severe shock but not after resuscitation increases hepatic injury and neutrophil accumulation in hemorrhaged rats.
    Shock (Augusta, Ga.), 1997, Volume: 8, Issue:6

    Topics: Alanine Transaminase; Animals; Antirheumatic Agents; Aspartate Aminotransferases; Endothelium; Enzym

1997
D-penicillamine induced Goodpasture's syndrome in Wilson's disease.
    Annals of internal medicine, 1975, Volume: 82, Issue:5

    Topics: Adult; Anti-Glomerular Basement Membrane Disease; Child; Female; Fluorescent Antibody Technique; Glo

1975
Platelet function and coagulation in patients with Wilson disease.
    Archives of internal medicine, 1976, Volume: 136, Issue:2

    Topics: Adolescent; Adult; Blood Coagulation; Blood Platelets; Child; Female; Hemorrhage; Hepatolenticular D

1976
Penicillamine associated pulmonary hemorrhage.
    The Journal of rheumatology, 1986, Volume: 13, Issue:5

    Topics: Adult; Antigen-Antibody Complex; Hemorrhage; Hepatolenticular Degeneration; Humans; Lung Diseases; M

1986
Deafness due to Waldenstrom macroglobulinaemia.
    The Journal of laryngology and otology, 1971, Volume: 85, Issue:3

    Topics: Audiometry; Blood Coagulation Disorders; Blood Coagulation Tests; Blood Proteins; Chlorambucil; Deaf

1971