penicillamine has been researched along with Benign Neoplasms in 28 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "However, the delivery of D-pen to cancer cells remains a challenge due to its high hydrophilicity, highly reactive thiol group and impermeability to the cell membrane." | 1.36 | Intracellular delivery of the reactive oxygen species generating agent D-penicillamine upon conjugation to poly-L-glutamic acid. ( Mumper, RJ; Wadhwa, S, 2010) |
| "Although membranous glomerulonephritis is deemed to be idiopathic in most cases, it seems warranted to search for medication, malignancy, SLE, HBV infection, syphilis and thyroiditis as possible aetiological factors." | 1.28 | Aetiology of membranous glomerulonephritis: a prospective study of 82 adult patients. ( Cahen, R; Francois, B; Gilly, J; Parchoux, B; Trolliet, P, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (60.71) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (25.00) | 29.6817 |
| 2010's | 4 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, R | 1 |
| Elf, S | 1 |
| Shan, C | 1 |
| Kang, HB | 1 |
| Ji, Q | 1 |
| Zhou, L | 1 |
| Hitosugi, T | 1 |
| Zhang, L | 1 |
| Zhang, S | 1 |
| Seo, JH | 1 |
| Xie, J | 1 |
| Tucker, M | 1 |
| Gu, TL | 1 |
| Sudderth, J | 1 |
| Jiang, L | 1 |
| Mitsche, M | 1 |
| DeBerardinis, RJ | 1 |
| Wu, S | 1 |
| Li, Y | 1 |
| Mao, H | 1 |
| Chen, PR | 1 |
| Wang, D | 1 |
| Chen, GZ | 1 |
| Hurwitz, SJ | 1 |
| Lonial, S | 1 |
| Arellano, ML | 1 |
| Khoury, HJ | 1 |
| Khuri, FR | 1 |
| Lee, BH | 1 |
| Lei, Q | 1 |
| Brat, DJ | 1 |
| Ye, K | 1 |
| Boggon, TJ | 1 |
| He, C | 1 |
| Kang, S | 1 |
| Fan, J | 1 |
| Chen, J | 1 |
| Taira, Y | 1 |
| Uehara, T | 1 |
| Tsuchiya, M | 1 |
| Takemori, H | 1 |
| Mizuno, Y | 1 |
| Takahashi, S | 1 |
| Suzuki, H | 1 |
| Hanaoka, H | 1 |
| Akizawa, H | 1 |
| Arano, Y | 1 |
| Gupte, A | 1 |
| Mumper, RJ | 2 |
| Wadhwa, S | 1 |
| Li, JW | 1 |
| Xia, L | 1 |
| Su, Y | 1 |
| Liu, H | 1 |
| Xia, X | 1 |
| Lu, Q | 1 |
| Yang, C | 1 |
| Reheman, K | 1 |
| Sproull, M | 1 |
| Brechbiel, M | 1 |
| Camphausen, K | 1 |
| EDWARDS, CL | 1 |
| GENGOZIAN, N | 1 |
| Brewer, GJ | 1 |
| Chvapil, M | 1 |
| Kielar, F | 1 |
| Liska, F | 1 |
| Silhankova, A | 1 |
| Brendel, K | 1 |
| Yokoyama, A | 1 |
| Horiuchi, K | 1 |
| Gärtner, HV | 1 |
| Krel', AA | 1 |
| Kanevskaia, MZ | 1 |
| Rashchupkina, ZP | 1 |
| Bolotin, EV | 1 |
| Chichasova, NV | 1 |
| Paulus, HE | 1 |
| Ruocco, V | 1 |
| Pisani, M | 1 |
| Vanchieri, C | 1 |
| Feger, F | 1 |
| Ferry-Dumazet, H | 1 |
| Mamani Matsuda, M | 1 |
| Bordenave, J | 1 |
| Dupouy, M | 1 |
| Nussler, AK | 1 |
| Arock, M | 1 |
| Devevey, L | 1 |
| Nafziger, J | 1 |
| Guillosson, JJ | 1 |
| Reiffers, J | 1 |
| Mossalayi, MD | 1 |
| Havre, PA | 1 |
| O'Reilly, S | 1 |
| McCormick, JJ | 1 |
| Brash, DE | 1 |
| Preece, AW | 2 |
| Light, PA | 2 |
| Evans, PA | 2 |
| Nunn, AD | 1 |
| Johnson, AG | 1 |
| Regal, J | 1 |
| Cahen, R | 1 |
| Francois, B | 1 |
| Trolliet, P | 1 |
| Gilly, J | 1 |
| Parchoux, B | 1 |
| Ziminski, CM | 1 |
| Merrill, JP | 1 |
| Tisman, G | 2 |
| Herbert, V | 2 |
| Go, LT | 1 |
| Brenner, L | 1 |
| Edlis, H | 1 |
| Chlud, K | 1 |
| Langendorff, H | 1 |
| Kölle, G | 1 |
6 reviews available for penicillamine and Benign Neoplasms
| Article | Year |
|---|---|
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; | 2015 |
Elevated copper and oxidative stress in cancer cells as a target for cancer treatment.
Topics: Chelating Agents; Copper; Humans; Neoplasms; Oxidative Stress; Penicillamine; Reactive Oxygen Specie | 2009 |
Antiangiogenic therapy through copper chelation.
Topics: Angiogenesis Inhibitors; Animals; Chelating Agents; Chelation Therapy; Copper; Corneal Neovasculariz | 2003 |
Anticopper therapy against cancer and diseases of inflammation and fibrosis.
Topics: Animals; Copper; Fibrosis; Humans; Inflammation; Molybdenum; Neoplasms; Neovascularization, Patholog | 2005 |
Glomerulonephritis (second of three parts).
Topics: Anti-Glomerular Basement Membrane Disease; Cryoglobulins; Drug Hypersensitivity; Endocarditis, Subac | 1974 |
[Recent results of research on the effect of chemical substances during irradiation of higher organisms].
Topics: Animals; Antimetabolites; Cricetinae; Dogs; Endotoxins; Guinea Pigs; Haplorhini; Homocysteine; Human | 1970 |
22 other studies available for penicillamine and Benign Neoplasms
| Article | Year |
|---|---|
Coordination-Mediated Synthesis of Purification-Free Bivalent
Topics: Animals; Cell Line, Tumor; Chelating Agents; Humans; Integrin alphaVbeta3; Male; Mice, Inbred BALB C | 2018 |
Intracellular delivery of the reactive oxygen species generating agent D-penicillamine upon conjugation to poly-L-glutamic acid.
Topics: Animals; Apoptosis; Cell Line, Tumor; Chelating Agents; Chromatography, High Pressure Liquid; HL-60 | 2010 |
Molecular imprint of enzyme active site by camel nanobodies: rapid and efficient approach to produce abzymes with alliinase activity.
Topics: Animals; Antibodies; Antibodies, Anti-Idiotypic; Binding Sites; Camelus; Carbon-Sulfur Lyases; Catal | 2012 |
AUTO-IMMUNE HEMOLYTIC ANEMIA TREATED WITH D-PENICILLAMINE; REPORT OF A CASE.
Topics: Anemia; Anemia, Hemolytic; Anemia, Hemolytic, Autoimmune; Autoantibodies; Blood Transfusion; Drug Th | 1965 |
Synthesis and evaluation of long-acting D-penicillamine derivatives.
Topics: Adenocarcinoma; Alcohols; Aminopropionitrile; Animals; Cicatrix, Hypertrophic; Collagen; Connective | 2005 |
Mononuclear and dinuclear complexes of 99mTc.
Topics: Bleomycin; Glutamates; Humans; Hydrogen-Ion Concentration; Indicators and Reagents; Neoplasms; Organ | 1982 |
Membranous (peri-, epi-, extramembranous) glomerulonephritis. Prototype of an immune complex glomerulonephritis. A clinical morphological study.
Topics: Adolescent; Adult; Age Factors; Aged; Biopsy; Blood Pressure; Child; Child, Preschool; Diabetes Comp | 1980 |
[Chlorbutin, azathioprine, D-penicillamine, and levamisole (Decaris) in the treatment of rheumatoid arthritis patients. I. Comparative analysis of side effects].
Topics: Arthritis, Rheumatoid; Azathioprine; Bronchial Spasm; Chlorambucil; Drug Eruptions; Dyspepsia; Human | 1981 |
An overview of benefit/risk of disease modifying treatment of rheumatoid arthritis as of today.
Topics: Arthritis, Rheumatoid; Azathioprine; Chloroquine; Cyclophosphamide; Female; Gold; Humans; Hydroxychl | 1982 |
Induced pemphigus.
Topics: Antibodies; Antigens; Autoantibodies; Burns; Humans; Neoplasms; Pemphigus; Penicillamine; Ultraviole | 1982 |
Cutting copper curbs angiogenesis, studies show.
Topics: Angiogenesis Inhibitors; Brain Neoplasms; Chelating Agents; Clinical Trials as Topic; Combined Modal | 2000 |
Role of iron in tumor cell protection from the pro-apoptotic effect of nitric oxide.
Topics: Apoptosis; Cell Cycle; Ferricyanides; Humans; Iron; Neoplasms; Nitric Oxide; Nitric Oxide Donors; Pe | 2001 |
Transformed and tumor-derived human cells exhibit preferential sensitivity to the thiol antioxidants, N-acetyl cysteine and penicillamine.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Cell Line; Cell Transformation, Neoplastic; Fibroblasts; Ge | 2002 |
Serum-copper, penicillamine, and cytotoxic therapy.
Topics: Bleomycin; Copper; Drug Interactions; Drug Therapy, Combination; Humans; Neoplasms; Penicillamine | 1977 |
Effects of 3,3-dimethylcysteine (D-penicillamine) on serum copper in subjects with malignant disease [proceedings].
Topics: Adolescent; Adult; Aged; Bleomycin; Ceruloplasmin; Copper; Female; Humans; Male; Middle Aged; Neopla | 1977 |
Immunotoxicity of immunotherapeutic agents.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Azathioprine; Cyclophosphamide; Cyclosporins; Glucocorticoids; Go | 1985 |
Aetiology of membranous glomerulonephritis: a prospective study of 82 adult patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Glomerulonephritis, Membranous; Humans; Lupus Er | 1989 |
Treating joint inflammation in the elderly: an update.
Topics: Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antimalarials; Arthritis; Arthritis, Infectio | 1985 |
Inhibition by penicillamine of DNA and protein synthesis by human bone marrow.
Topics: Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Copper; Deoxyuridine; Depression, Chemical; DNA; Fo | 1972 |
Determination of therapeutic index of drugs by in vitro sensitivity tests using human host and tumor cell suspensions.
Topics: Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Deoxyuridine; DNA, Neoplasm; | 1973 |
[Clinical picture of rheumatologic diseases. Current status of cytostatic therapy].
Topics: Antineoplastic Agents; Arthritis, Rheumatoid; Azathioprine; Chlorambucil; Cyclophosphamide; Humans; | 1974 |
[Clinical aspects of immunosuppressive therapy in childhood rheumatoid arthritis].
Topics: Adrenal Cortex Hormones; Alkylating Agents; Arthritis, Juvenile; Azathioprine; Child; Humans; Immuni | 1972 |