penicillamine has been researched along with Autoimmune Disease in 88 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the present study, the side effects of d-Penicillamine therapy in 54 patients with rheumatoid arthritis are analyzed." | 8.77 | [Side effects of d-penicillamine in the treatment of rheumatoid arthritis]. ( Bianchini, D; Cataldo, R; Damiani, D; Florean, M; Mazzanti, G; Mesesnel, E; Paladini, G, 1986) |
| "The anti-rheumatoid drug D-penicillamine (D-pen) has a reactive sulfhydryl group capable of modifying self antigens, and can provoke typical autoantibody-mediated myasthenia gravis (MG), especially in DR1+ individuals." | 7.70 | T cell responses to D-penicillamine in drug-induced myasthenia gravis: recognition of modified DR1:peptide complexes. ( Hill, M; Moss, P; Newsom-Davis, J; Willcox, N; Wordsworth, P, 1999) |
| "A 51-year-old man developed pemphigus vulgaris, minimal change nephropathy and acute tubular necrosis after 11 months of treatment with penicillamine for rheumatoid arthritis associated with features of Reiter's syndrome." | 7.67 | Minimal change nephropathy and pemphigus vulgaris associated with penicillamine treatment of rheumatoid arthritis. ( Chia, Y; Pusey, CD; Savill, JS, 1988) |
| "The development of autoimmune diseases in some patients treated with D-penicillamine (DPA) suggests that the reported occurrence of a conduction disorder at the neuromuscular junction and the development of a reversible myasthenia gravis in rheumatoid disease, progressive systemic sclerosis or Wilson's disease after the use of DPA are part of a general predisposition for autoimmune disease related to DPA therapy." | 7.67 | [Myasthenia gravis induced by D-penicillamine in a patient with progressive systemic sclerosis]. ( Cossermelli, W; De Assis, JL; Marchiori, PE; Scaff, M, 1984) |
| "A pilot study of the effect of D-penicillamine in multiple sclerosis (MS) was undertaken because of D-penicillamine's activity against RNA neurotropic viruses, because it is effective against the auto-immune disease, rheumatoid arthritis, and because both viruses and autoimmunity have been implicated in multiple sclerosis." | 7.66 | Pilot study of d-penicillamine, vitamins and minerals in multiple sclerosis. ( Alba, A; Berger, AR; Rudez, A; Seelig, MS; Tarlau, M, 1978) |
| "The authors present 5 cases of pemphigus induced by D-penicillamine in a series of 180 cases of rheumatoid arthritis treated with this medication." | 7.65 | [Pemphigus induced by D-penicillamine in rheumatoid arthritis. Study of 5 cases and systematic study of anti-intercellular substance antibodies of the skin in the course of treatment]. ( Benveniste, M; Camus, JP; Crouzet, J; Hewitt, J; Homberg, JC; Lessana, M, 1975) |
| "Proteinuria is observed in 10% of the patients, often secondary to extramembranous glomerulopathy." | 5.30 | [Extracapillary glomerulonephritis with anti-myeloperoxidase antibodies in 2 patients with systemic scleroderma treated with penicillamine D]. ( Bridoux, F; Ducq, P; Gheerbrant, JD; Kyndt, X; Makdassi, R; Reumaux, D; Vanhille, P, 1999) |
| "We report a patient with primary biliary cirrhosis, who developed polymyositis while receiving D-penicillamine therapy." | 5.29 | A case of polymyositis in a patient with primary biliary cirrhosis treated with D-penicillamine. ( Ahn, JH; Kim, TH; Peck, KR; Song, YW, 1993) |
| " Three to eight weeks after D-penicillamine administration in a dosage of 20 to 50 mg per day, 73% of Brown Norway (BN) rats became ill." | 5.27 | Effects of prolonged administration of D-penicillamine or captopril in various strains of rats. Brown Norway rats treated with D-penicillamine develop autoantibodies, circulating immune complexes, and disseminated intravascular coagulation. ( Andres, GA; Brentjens, JR; Donker, AJ; Venuto, RC; Vladutiu, AO, 1984) |
| " Its indications in the therapy of RA were defined, and current principles of dosage were presented." | 5.26 | Penicillamine in rheumatoid arthritis: clinical pharmacology and biochemical properties. ( Jaffe, IA, 1979) |
| "In the present study, the side effects of d-Penicillamine therapy in 54 patients with rheumatoid arthritis are analyzed." | 4.77 | [Side effects of d-penicillamine in the treatment of rheumatoid arthritis]. ( Bianchini, D; Cataldo, R; Damiani, D; Florean, M; Mazzanti, G; Mesesnel, E; Paladini, G, 1986) |
| "Mercury and gold salts as well as d-penicillamine can cause glomerulonephritis by an autoimmune mechanism in man." | 4.77 | Immunogenetically controlled autoimmune reactions induced by mercury, gold and D-penicillamine in laboratory animals: a review from the vantage point of premarketing safety studies. ( Balazs, T, 1987) |
| " We tested this hypothesis in an animal model in which penicillamine causes an autoimmune syndrome in Brown Norway rats." | 3.71 | Factors that modify penicillamine-induced autoimmunity in Brown Norway rats: failure of the Th1/Th2 paradigm. ( Sayeh, E; Uetrecht, JP, 2001) |
| "The anti-rheumatoid drug D-penicillamine (D-pen) has a reactive sulfhydryl group capable of modifying self antigens, and can provoke typical autoantibody-mediated myasthenia gravis (MG), especially in DR1+ individuals." | 3.70 | T cell responses to D-penicillamine in drug-induced myasthenia gravis: recognition of modified DR1:peptide complexes. ( Hill, M; Moss, P; Newsom-Davis, J; Willcox, N; Wordsworth, P, 1999) |
| "D-penicillamine (DP) has been previously shown to induce an autoimmune disease in Brown-Norway (BN) rats, characterized by a dermatitis, by the production of antinuclear antibodies, by the formation fo circulating immune complexes, and by linear IgG deposits along the glomerular basement membrane." | 3.68 | D-penicillamine-induced autoimmunity in Brown-Norway rats. Similarities with HgCl2-induced autoimmunity. ( Druet, P; Mandet, C; Pasquier, R; Pelletier, L; Tournade, H; Vial, MC, 1990) |
| "The development of autoimmune diseases in some patients treated with D-penicillamine (DPA) suggests that the reported occurrence of a conduction disorder at the neuromuscular junction and the development of a reversible myasthenia gravis in rheumatoid disease, progressive systemic sclerosis or Wilson's disease after the use of DPA are part of a general predisposition for autoimmune disease related to DPA therapy." | 3.67 | [Myasthenia gravis induced by D-penicillamine in a patient with progressive systemic sclerosis]. ( Cossermelli, W; De Assis, JL; Marchiori, PE; Scaff, M, 1984) |
| "A 51-year-old man developed pemphigus vulgaris, minimal change nephropathy and acute tubular necrosis after 11 months of treatment with penicillamine for rheumatoid arthritis associated with features of Reiter's syndrome." | 3.67 | Minimal change nephropathy and pemphigus vulgaris associated with penicillamine treatment of rheumatoid arthritis. ( Chia, Y; Pusey, CD; Savill, JS, 1988) |
| "Penicillamine is now established as a useful disease remittive drug in the treatment of rheumatoid arthritis." | 3.66 | Penicillamine: an anti-rheumatoid drug. ( Jaffe, IA, 1983) |
| "The prevalence of autoimmune associations was determined in 113 patients with primary biliary cirrhosis who participated in a therapeutic trial of D-penicillamine." | 3.66 | Autoimmune associations in primary biliary cirrhosis. ( Baldus, WP; Culp, KS; Dickson, ER; Duffy, J; Fleming, CR, 1982) |
| "A pilot study of the effect of D-penicillamine in multiple sclerosis (MS) was undertaken because of D-penicillamine's activity against RNA neurotropic viruses, because it is effective against the auto-immune disease, rheumatoid arthritis, and because both viruses and autoimmunity have been implicated in multiple sclerosis." | 3.66 | Pilot study of d-penicillamine, vitamins and minerals in multiple sclerosis. ( Alba, A; Berger, AR; Rudez, A; Seelig, MS; Tarlau, M, 1978) |
| " Masugi nephritis, heterologous and autologous immune complex nephritis as well as D-penicillamine induced glomerulonephritis were studied in rabbits, guinea pigs and rats." | 3.65 | Molecular weight analysis of proteinuria in experimental glomerulopathies. ( Batsford, SR; Boesken, WH; Schmitz-Hübner, U; Schneider, G, 1976) |
| "The authors present 5 cases of pemphigus induced by D-penicillamine in a series of 180 cases of rheumatoid arthritis treated with this medication." | 3.65 | [Pemphigus induced by D-penicillamine in rheumatoid arthritis. Study of 5 cases and systematic study of anti-intercellular substance antibodies of the skin in the course of treatment]. ( Benveniste, M; Camus, JP; Crouzet, J; Hewitt, J; Homberg, JC; Lessana, M, 1975) |
| "In this subset of patients with primary biliary cirrhosis, a significantly higher prevalence (86 percent) of circulating immune complexes was detected compared with those patients showing no autoimmune features (60 percent)." | 2.65 | Immune complexes in primary biliary cirrhosis. Higher prevalence of circulating immune complexes in patients with associated autoimmune features. ( Baggenstoss, AH; Dickson, ER; Gupta, RC; McDuffie, FC, 1982) |
| "Ursodeoxycholic acid has been shown to improve survival free of transplantation in a conclusive fashion." | 2.40 | Management of primary biliary cirrhosis and autoimmune cholangitis. ( Angulo, P; Lindor, KD, 1998) |
| "Drug-induced autoimmune diseases have two immunological peculiarities." | 2.37 | [Autoimmunity induced by drugs. Immunological characteristics and etiopathogenic hypotheses]. ( Homberg, JC, 1984) |
| "Many of the adverse reactions produced by penicillamine and other compounds with an active sulfhydryl group form a distinctive pattern when viewed as a class." | 2.37 | Adverse effects profile of sulfhydryl compounds in man. ( Jaffe, IA, 1986) |
| " The types of cutaneous manifestations may, in some instances, be correlated with the disease being treated and the dosage and duration of penicillamine therapy." | 2.36 | Penicillamine: review and cutaneous manifestations. ( Alter, JN; Fisher, M; Levy, RS, 1983) |
| "Pemphigus is an autoimmune intraepidermal bullous disease involving the skin and mucous membranes." | 2.36 | Pemphigus: current concepts. ( , 1980) |
| "We retrospectively analyzed 235 Wilson disease patients." | 1.43 | Concomitant immune-related events in Wilson disease: implications for monitoring chelator therapy. ( Ferenci, P; Gohdes, A; Gotthardt, DN; Pfeiffenberger, J; Schäfer, M; Seessle, J; Stremmel, W; Weiss, KH, 2016) |
| "Co-occurence of systemic sclerosis and collagenous colitis is particularly rare." | 1.34 | Collagenous colitis in a patient with systemic sclerosis: a rare entity. ( Coban, S; Ekiz, F; Ensari, A; Gören, D; Ormeci, N; Savas, B, 2007) |
| "Two patients had systemic sclerosis and one had rheumatoid arthritis." | 1.32 | [Minimal changes nephrotic syndrome associated to penicillamine treatment]. ( Basterrechea, MA; de Arriba, G; García-Martín, F; Giménez-Vega, E; Sánchez, J; Sánchez-Heras, M, 2004) |
| "Proteinuria is observed in 10% of the patients, often secondary to extramembranous glomerulopathy." | 1.30 | [Extracapillary glomerulonephritis with anti-myeloperoxidase antibodies in 2 patients with systemic scleroderma treated with penicillamine D]. ( Bridoux, F; Ducq, P; Gheerbrant, JD; Kyndt, X; Makdassi, R; Reumaux, D; Vanhille, P, 1999) |
| "We report a patient with primary biliary cirrhosis, who developed polymyositis while receiving D-penicillamine therapy." | 1.29 | A case of polymyositis in a patient with primary biliary cirrhosis treated with D-penicillamine. ( Ahn, JH; Kim, TH; Peck, KR; Song, YW, 1993) |
| " Three to eight weeks after D-penicillamine administration in a dosage of 20 to 50 mg per day, 73% of Brown Norway (BN) rats became ill." | 1.27 | Effects of prolonged administration of D-penicillamine or captopril in various strains of rats. Brown Norway rats treated with D-penicillamine develop autoantibodies, circulating immune complexes, and disseminated intravascular coagulation. ( Andres, GA; Brentjens, JR; Donker, AJ; Venuto, RC; Vladutiu, AO, 1984) |
| " Its indications in the therapy of RA were defined, and current principles of dosage were presented." | 1.26 | Penicillamine in rheumatoid arthritis: clinical pharmacology and biochemical properties. ( Jaffe, IA, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 62 (70.45) | 18.7374 |
| 1990's | 14 (15.91) | 18.2507 |
| 2000's | 8 (9.09) | 29.6817 |
| 2010's | 4 (4.55) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rozina, T | 1 |
| Fastovets, S | 1 |
| Lee, O | 1 |
| Kuchieva, A | 1 |
| Bulanov, N | 1 |
| Moiseev, S | 1 |
| Metushi, IG | 1 |
| Zhu, X | 2 |
| Uetrecht, J | 1 |
| Seessle, J | 1 |
| Gotthardt, DN | 1 |
| Schäfer, M | 1 |
| Gohdes, A | 1 |
| Pfeiffenberger, J | 1 |
| Ferenci, P | 1 |
| Stremmel, W | 1 |
| Weiss, KH | 1 |
| Li, J | 1 |
| Liu, F | 1 |
| Uetrecht, JP | 3 |
| DACIE, JV | 1 |
| COSTEA, N | 1 |
| YAKULIS, V | 1 |
| HELLER, P | 1 |
| Basterrechea, MA | 1 |
| de Arriba, G | 1 |
| García-Martín, F | 1 |
| Sánchez-Heras, M | 1 |
| Giménez-Vega, E | 1 |
| Sánchez, J | 1 |
| Shenton, JM | 1 |
| Chen, J | 1 |
| Angulo, P | 1 |
| Lindor, KD | 1 |
| Chuang, E | 1 |
| Molitch, ME | 1 |
| Ekiz, F | 1 |
| Coban, S | 1 |
| Savas, B | 1 |
| Gören, D | 1 |
| Ensari, A | 1 |
| Ormeci, N | 1 |
| Beaumont, JL | 1 |
| Beaumont, V | 1 |
| Jacotot, B | 1 |
| Kaeser, HE | 1 |
| Levy, RS | 1 |
| Fisher, M | 1 |
| Alter, JN | 1 |
| Homberg, JC | 2 |
| Donker, AJ | 1 |
| Venuto, RC | 1 |
| Vladutiu, AO | 1 |
| Brentjens, JR | 1 |
| Andres, GA | 1 |
| Weening, JJ | 1 |
| Epstein, O | 2 |
| Marchiori, PE | 1 |
| Scaff, M | 1 |
| Cossermelli, W | 1 |
| De Assis, JL | 1 |
| Moutsopoulos, HM | 1 |
| Giotaki, H | 1 |
| Maddison, PJ | 1 |
| Mavridis, AC | 1 |
| Drosos, AA | 1 |
| Skopouli, FN | 1 |
| Jaffe, IA | 4 |
| Stein, HB | 1 |
| Chalmers, A | 1 |
| Schroeder, ML | 1 |
| Dillon, A | 1 |
| Thomas, HC | 1 |
| Brown, D | 1 |
| Labrooy, J | 1 |
| Culp, KS | 1 |
| Fleming, CR | 1 |
| Duffy, J | 1 |
| Baldus, WP | 1 |
| Dickson, ER | 2 |
| Holborow, EJ | 1 |
| Mariani, L | 1 |
| Baratelli, M | 1 |
| Gupta, RC | 1 |
| McDuffie, FC | 1 |
| Baggenstoss, AH | 1 |
| Seelig, MS | 2 |
| Barthel, HR | 1 |
| Hiepe, F | 1 |
| Monestier, M | 1 |
| Novick, KE | 1 |
| Losman, MJ | 1 |
| Yodfat, O | 1 |
| Shoenfeld, Y | 1 |
| Ahn, JH | 1 |
| Kim, TH | 1 |
| Peck, KR | 1 |
| Song, YW | 1 |
| Ferro, J | 1 |
| Susano, R | 1 |
| Gómez, C | 1 |
| de Quirós, JF | 1 |
| Nässberger, L | 1 |
| Mathieson, PW | 1 |
| Peat, DS | 1 |
| Short, A | 1 |
| Watts, RA | 1 |
| Zettl, UK | 1 |
| Mix, E | 1 |
| Zielasek, J | 1 |
| Stangel, M | 1 |
| Hartung, HP | 1 |
| Gold, R | 1 |
| Kyndt, X | 1 |
| Ducq, P | 1 |
| Bridoux, F | 1 |
| Reumaux, D | 1 |
| Makdassi, R | 1 |
| Gheerbrant, JD | 1 |
| Vanhille, P | 1 |
| Hill, M | 1 |
| Moss, P | 1 |
| Wordsworth, P | 1 |
| Newsom-Davis, J | 1 |
| Willcox, N | 1 |
| White, KL | 1 |
| David, DW | 1 |
| Butterworth, LF | 1 |
| Klykken, PC | 1 |
| Okada, J | 1 |
| Kondo, H | 1 |
| Sayeh, E | 1 |
| Cozzi, F | 1 |
| Marson, P | 1 |
| Rosada, M | 1 |
| De Silvestro, G | 1 |
| Bullo, A | 1 |
| Punzi, L | 1 |
| Todesco, S | 1 |
| Seipelt, H | 1 |
| Feist, D | 1 |
| Boesken, WH | 1 |
| Batsford, SR | 1 |
| Schmitz-Hübner, U | 1 |
| Schneider, G | 1 |
| Williams, R | 1 |
| Eddleston, AL | 1 |
| Wallach, D | 1 |
| Pecking, A | 1 |
| Delvincourt, C | 1 |
| Cottenot, F | 1 |
| Najean, Y | 1 |
| Alba, A | 1 |
| Berger, AR | 1 |
| Rudez, A | 1 |
| Tarlau, M | 1 |
| Delrieu, F | 2 |
| Menkes, CJ | 2 |
| Sainte-Croix, A | 2 |
| Babinet, P | 2 |
| Chesneau, AM | 2 |
| Delbarre, F | 2 |
| Schumacher, K | 1 |
| Benveniste, M | 1 |
| Crouzet, J | 1 |
| Lessana, M | 1 |
| Camus, JP | 1 |
| Hewitt, J | 1 |
| Hrncír, Z | 2 |
| Tichý, M | 1 |
| Herranz, L | 1 |
| Rovira, A | 1 |
| Grande, C | 1 |
| Suarez, A | 1 |
| Martinez-Ara, J | 1 |
| Pallardo, LF | 1 |
| Gómez-Pan, A | 1 |
| Rook, AH | 1 |
| Tournade, H | 1 |
| Pelletier, L | 1 |
| Pasquier, R | 1 |
| Vial, MC | 1 |
| Mandet, C | 1 |
| Druet, P | 1 |
| Kjernsmo, A | 1 |
| Haberhauer, G | 1 |
| Verroust, PJ | 1 |
| Weitoft, T | 1 |
| Domeij-Nyberg, B | 1 |
| Kerwar, SS | 1 |
| Oronsky, AL | 1 |
| Meyer, O | 1 |
| Howard-Lock, HE | 1 |
| Lock, CJ | 1 |
| Mewa, A | 1 |
| Kean, WF | 1 |
| Mazzanti, G | 1 |
| Paladini, G | 1 |
| Damiani, D | 1 |
| Bianchini, D | 1 |
| Florean, M | 1 |
| Mesesnel, E | 1 |
| Cataldo, R | 1 |
| Spears, CJ | 1 |
| Batchelor, JR | 1 |
| Smiley, JD | 1 |
| Moore, SE | 1 |
| Balazs, T | 1 |
| Benenson, EV | 1 |
| Savill, JS | 1 |
| Chia, Y | 1 |
| Pusey, CD | 1 |
| Mackinnon, M | 1 |
| Cooksley, WG | 1 |
| Smallwood, RA | 1 |
| Seideman, P | 1 |
| Warnes, TW | 1 |
| Taal, BG | 1 |
| Schalm, SW | 1 |
| Stacher, A | 1 |
| Schraeder, PL | 1 |
| Peters, HA | 1 |
| Dahl, DS | 1 |
| Barnett, EV | 1 |
| Bluestone, R | 1 |
| Cracchiolo, A | 1 |
| Goldberg, LS | 1 |
| Kantor, GL | 1 |
| McIntosh, RM | 1 |
| Currey, HL | 1 |
| Metz, J | 1 |
| Bettendorf, U | 1 |
| Neuhaus, R | 1 |
| Mlczoch, F | 1 |
| Kormendy, CG | 1 |
| Bender, AD | 1 |
| Becker, K | 1 |
| Bernasconi, C | 1 |
| Pontiggia, P | 1 |
| Lazzarino, M | 1 |
| Follini, D | 1 |
| Salvaneschi, L | 1 |
26 reviews available for penicillamine and Autoimmune Disease
| Article | Year |
|---|---|
Management of primary biliary cirrhosis and autoimmune cholangitis.
Topics: Adrenal Cortex Hormones; Autoimmune Diseases; Cholangitis; Colchicine; Disease Progression; Drug The | 1998 |
Drug-induced myasthenic syndromes.
Topics: Adrenergic beta-Antagonists; Adult; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Autoimmune Diseas | 1984 |
Penicillamine: review and cutaneous manifestations.
Topics: Autoimmune Diseases; Collagen; Dermatitis, Atopic; Drug Eruptions; Elastin; Humans; Lichen Planus; P | 1983 |
[Autoimmunity induced by drugs. Immunological characteristics and etiopathogenic hypotheses].
Topics: Animals; Autoimmune Diseases; Cardiac Glycosides; Chemical and Drug Induced Liver Injury; Drug Combi | 1984 |
T cell subsets in autoimmune and HBV-induced chronic liver disease, HBs antigen carriers with normal histology and primary biliary cirrhosis: a review of the abnormalities and the effects of treatment.
Topics: Antibodies, Monoclonal; Autoimmune Diseases; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surfac | 1982 |
Pemphigus: current concepts.
Topics: Acantholysis; Adrenal Cortex Hormones; Autoimmune Diseases; Binding Sites, Antibody; Gold; Humans; I | 1980 |
[Anti-inflammatory or antirheumatic agents? Pharmacological activity and therapeutic effectiveness of non-steroid anti-inflammatory drugs: comparative study. III].
Topics: Adjuvants, Immunologic; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Autoimmune Diseases; Chloro | 1980 |
Induction of auto-immune syndromes by penicillamine therapy in rheumatoid arthritis and other diseases.
Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Captopril; Cystinuria; Hepatolenticular Degeneration; Hu | 1981 |
[Lupus erythematosus and liver diseases].
Topics: Autoimmune Diseases; Budd-Chiari Syndrome; Chelating Agents; Hepatitis; Hepatitis, Chronic; Hepatole | 1995 |
[Penicillamine--friend or enemy?].
Topics: Animals; Autoimmune Diseases; Humans; Immune System; Penicillamine; Penicillins | 1994 |
Coexistent membranous nephropathy and ANCA-positive crescentic glomerulonephritis in association with penicillamine.
Topics: Antibodies, Antineutrophil Cytoplasmic; Antirheumatic Agents; Arthritis, Rheumatoid; Autoantibodies; | 1996 |
Assessment of autoimmunity-inducing potential using the brown Norway rat challenge model.
Topics: Animals; Anti-Infective Agents, Local; Antibody Formation; Antidotes; Autoimmune Diseases; Disease M | 2000 |
[Other autoimmune diseases].
Topics: Autoantibodies; Autoimmune Diseases; Halothane; Humans; Metals, Heavy; Penicillamine; Phenytoin | 2000 |
Chronic active hepatitis: immunopathogenesis and immunotherapy.
Topics: Antibodies, Viral; Antilymphocyte Serum; Autoimmune Diseases; Azathioprine; Carrier State; Chronic D | 1979 |
Photopheresis in the treatment of autoimmune disease: experience with pemphigus vulgaris and systemic sclerosis.
Topics: Autoimmune Diseases; Humans; Leukapheresis; Pemphigus; Penicillamine; PUVA Therapy; Scleroderma, Sys | 1991 |
Adverse effects profile of sulfhydryl compounds in man.
Topics: Anemia, Aplastic; Autoimmune Diseases; Captopril; Drug Eruptions; Glomerulonephritis; Humans; Neutro | 1986 |
D-penicillamine: chemistry and clinical use in rheumatic disease.
Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Drug Eruptions; Gold Sodium Thiomalate; Hematologic Dise | 1986 |
[Side effects of d-penicillamine in the treatment of rheumatoid arthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Autoimmune Diseases; Drug Eruptions; Female; Hematologic Disease | 1986 |
Drug-induced autoimmune disease.
Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Gold; HLA Antigens; Humans; Hydralazine; Lupus Erythemat | 1987 |
Molecular mechanisms of autoimmunity.
Topics: Antibodies, Antinuclear; Autoantibodies; Autoimmune Diseases; B-Lymphocytes; DNA; Humans; Immunoglob | 1988 |
Immunogenetically controlled autoimmune reactions induced by mercury, gold and D-penicillamine in laboratory animals: a review from the vantage point of premarketing safety studies.
Topics: Animals; Autoimmune Diseases; Glomerulonephritis; Gold; Mercury; Mice; Mice, Inbred Strains; Penicil | 1987 |
Chronic hepatitis: pathogenesis and treatment.
Topics: Adrenal Cortex Hormones; Antigens, Viral; Antiviral Agents; Autoimmune Diseases; Cytotoxicity, Immun | 1986 |
Treatment of primary biliary cirrhosis.
Topics: Adrenal Cortex Hormones; Autoimmune Diseases; Azathioprine; Chlorambucil; Cholelithiasis; Colchicine | 1985 |
Immunosuppressive drugs in rheumatoid arthritis.
Topics: Adrenocorticotropic Hormone; Aminopterin; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Autoimmun | 1971 |
[Penicillamine (dimethylcysteine) in the treatment of autoimmune diseases. (Summary review with reporting of personal experiences)].
Topics: Autoimmune Diseases; Collagen Diseases; Erythrocyte Aging; Hemagglutination Tests; Humans; Immunoglo | 1969 |
Chemical interference with aging.
Topics: Adrenal Cortex Hormones; Aging; Animals; Antioxidants; Appetite Depressants; Autoimmune Diseases; Br | 1971 |
5 trials available for penicillamine and Autoimmune Disease
| Article | Year |
|---|---|
Immune complexes in primary biliary cirrhosis. Higher prevalence of circulating immune complexes in patients with associated autoimmune features.
Topics: Antigen-Antibody Complex; Autoantibodies; Autoimmune Diseases; Complement Activation; Humans; Liver | 1982 |
Long-term therapy with plasma exchange in systemic sclerosis: effects on laboratory markers reflecting disease activity.
Topics: Adult; Aged; Antibody Specificity; Autoantibodies; Autoimmune Diseases; Biomarkers; Combined Modalit | 2001 |
Chronic active hepatitis: immunopathogenesis and immunotherapy.
Topics: Antibodies, Viral; Antilymphocyte Serum; Autoimmune Diseases; Azathioprine; Carrier State; Chronic D | 1979 |
Cryoglobulins in primary biliary cirrhosis: prevalence and modulation by immunosuppressive therapy.
Topics: Adult; Aged; Alkaline Phosphatase; Autoantibodies; Autoimmune Diseases; Clinical Trials as Topic; Cr | 1985 |
Immunosuppressive drugs in rheumatoid arthritis.
Topics: Adrenocorticotropic Hormone; Aminopterin; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Autoimmun | 1971 |
59 other studies available for penicillamine and Autoimmune Disease
| Article | Year |
|---|---|
D-penicillamine-induced autoimmune disorders.
Topics: Adult; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Autoimmune Diseases; Autoimmunity | 2019 |
D-penicillamine-induced granulomatous hepatitis in brown Norway rats.
Topics: Alanine Transaminase; Animals; Autoimmune Diseases; CD8-Positive T-Lymphocytes; Chemical and Drug In | 2014 |
Concomitant immune-related events in Wilson disease: implications for monitoring chelator therapy.
Topics: Adolescent; Adult; Antibodies, Antinuclear; Autoimmune Diseases; Chelating Agents; Child; Cross-Sect | 2016 |
Involvement of T helper 17 cells in D-penicillamine-induced autoimmune disease in Brown Norway rats.
Topics: Animals; Autoimmune Diseases; Autoimmunity; Cytokines; Disease Models, Animal; Flow Cytometry; Leuko | 2011 |
[THE COLD HEMAGGLUTININ SYNDROME].
Topics: Anemia, Hemolytic; Autoimmune Diseases; Blood Transfusion; Cold Temperature; Cyanosis; Hemagglutinat | 1964 |
EXPERIMENTAL PRODUCTION OF COLD AGGLUTININS IN RABBITS.
Topics: Animals; Antibodies; Autoimmune Diseases; Chromatography; Chromium Isotopes; Cold Temperature; Cryog | 1965 |
[Minimal changes nephrotic syndrome associated to penicillamine treatment].
Topics: Adult; Arthritis, Rheumatoid; Autoimmune Diseases; Female; Humans; Immunosuppressive Agents; Middle | 2004 |
Animal models of idiosyncratic drug reactions.
Topics: Adverse Drug Reaction Reporting Systems; Animals; Autoimmune Diseases; Drug-Related Side Effects and | 2004 |
Prolactin and autoimmune diseases in humans.
Topics: Aminoquinolines; Animals; Arthritis, Rheumatoid; Autoimmune Diseases; Bromocriptine; Cabergoline; Cy | 2007 |
Collagenous colitis in a patient with systemic sclerosis: a rare entity.
Topics: Abdomen; Aged; Autoimmune Diseases; Colitis, Collagenous; Comorbidity; Diarrhea; Female; Humans; Lop | 2007 |
[A further case of hyperlipemia due to auto-antibodies. Its treatment with D-penicillamine].
Topics: Arteriosclerosis Obliterans; Autoimmune Diseases; Female; Humans; Hyperlipidemias; Middle Aged; Peni | 1967 |
Effects of prolonged administration of D-penicillamine or captopril in various strains of rats. Brown Norway rats treated with D-penicillamine develop autoantibodies, circulating immune complexes, and disseminated intravascular coagulation.
Topics: Animals; Antibodies, Antinuclear; Antigen-Antibody Complex; Autoantibodies; Autoimmune Diseases; Bas | 1984 |
Autoimmune reactions and glomerulonephritis caused by heavy metals and other toxins.
Topics: Animals; Autoimmune Diseases; Captopril; Glomerulonephritis; Gold; Humans; Mercury; Metals; Penicill | 1983 |
Lichen planus and liver disease.
Topics: Autoimmune Diseases; Chronic Disease; Female; Hepatitis, Chronic; Humans; Lichen Planus; Liver Cirrh | 1984 |
[Myasthenia gravis induced by D-penicillamine in a patient with progressive systemic sclerosis].
Topics: Adult; Autoimmune Diseases; Female; Humans; Myasthenia Gravis; Neuromuscular Junction; Penicillamine | 1984 |
Antibodies to cellular antigens in Greek patients with autoimmune rheumatic diseases: anti-Ro(SSA) antibody a possible marker of penicillamine-D intolerance.
Topics: Adult; Aged; Antigens; Arthritis, Rheumatoid; Autoantibodies; Autoantigens; Autoimmune Diseases; Fem | 1984 |
Penicillamine: an anti-rheumatoid drug.
Topics: Antigen-Antibody Complex; Arthritis, Rheumatoid; Autoimmune Diseases; Drug Administration Schedule; | 1983 |
Selected adverse reactions of D-penicillamine.
Topics: Adult; Arthritis, Rheumatoid; Autoimmune Diseases; Bronchiolitis, Viral; Cholestasis; Female; Humans | 1984 |
Autoimmune associations in primary biliary cirrhosis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Autoimmune Diseases; Female; Humans; Immunoglobulins; Keratoconj | 1982 |
Drug effects on autoantibodies and immune complexes.
Topics: Acetylation; Antibodies, Antinuclear; Antigen-Antibody Complex; Arthritis, Rheumatoid; Autoantibodie | 1980 |
Auto-immune complications of D-penicillamine--a possible result of zinc and magnesium depletion and of pyridoxine inactivation.
Topics: Autoimmune Diseases; Humans; Magnesium; Magnesium Deficiency; Penicillamine; Pyridoxine; Vitamin B 6 | 1982 |
D-penicillamine- and quinidine-induced antinuclear antibodies in A.SW (H-2s) mice: similarities with autoantibodies in spontaneous and heavy metal-induced autoimmunity.
Topics: Amino Acid Sequence; Animals; Antibodies, Antinuclear; Antibodies, Monoclonal; Antibody Specificity; | 1994 |
A case of polymyositis in a patient with primary biliary cirrhosis treated with D-penicillamine.
Topics: Autoimmune Diseases; Female; Humans; Liver Cirrhosis, Biliary; Middle Aged; Penicillamine; Polymyosi | 1993 |
[Myasthenia induced by penicillamine: does an interaction with tricyclic antidepressants exist?].
Topics: Aged; Antidepressive Agents, Tricyclic; Arthritis, Rheumatoid; Autoimmune Diseases; Drug Interaction | 1993 |
Granulocyte autoantibodies--markers for drug-induced autoimmune adverse effects.
Topics: Antibodies, Antineutrophil Cytoplasmic; Autoantibodies; Autoimmune Diseases; Biomarkers; Glomerulone | 1993 |
Apoptosis of myelin-reactive T cells induced by reactive oxygen and nitrogen intermediates in vitro.
Topics: Animals; Apoptosis; Autoimmune Diseases; CD4-Positive T-Lymphocytes; Cells, Cultured; DNA Fragmentat | 1997 |
[Extracapillary glomerulonephritis with anti-myeloperoxidase antibodies in 2 patients with systemic scleroderma treated with penicillamine D].
Topics: Aged; Antibodies, Antineutrophil Cytoplasmic; Autoimmune Diseases; Female; Glomerulonephritis; Human | 1999 |
T cell responses to D-penicillamine in drug-induced myasthenia gravis: recognition of modified DR1:peptide complexes.
Topics: Aged; Amino Acid Sequence; Antirheumatic Agents; Autoimmune Diseases; Base Sequence; Blood Proteins; | 1999 |
Factors that modify penicillamine-induced autoimmunity in Brown Norway rats: failure of the Th1/Th2 paradigm.
Topics: Animals; Autoimmune Diseases; Autoimmunity; Drug Eruptions; Immunoglobulin E; Interferon Inducers; I | 2001 |
[Drug immunosuppression].
Topics: Alkylating Agents; Anemia, Hemolytic, Autoimmune; Antimetabolites; Arthritis; Arthritis, Juvenile; A | 1975 |
[Studies on juvenile chronic hepatitis].
Topics: Alanine Transaminase; Aspartate Aminotransferases; Autoantibodies; Autoimmune Diseases; Azathioprine | 1975 |
Molecular weight analysis of proteinuria in experimental glomerulopathies.
Topics: Animals; Autoimmune Diseases; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Glomerulo | 1976 |
Penicillamine in rheumatoid arthritis: clinical pharmacology and biochemical properties.
Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Collagen; Cystine; Drug Evaluation; Humans; Penicillamin | 1979 |
[Gougerot-Sjögren's syndrome and pemphigus. Parallel development of the dryness syndrome and auto-immune dermatosis].
Topics: Adult; Autoimmune Diseases; Humans; Male; Pemphigus; Penicillamine; Salivary Glands; Sjogren's Syndr | 1979 |
Pilot study of d-penicillamine, vitamins and minerals in multiple sclerosis.
Topics: Adult; Autoimmune Diseases; Brain; Dose-Response Relationship, Drug; Female; Humans; Magnesium; Male | 1978 |
[Myasthenia gravis and autoimmune thyroiditis during the treatment of rheumatoid polyarthritis withD-penicillamine. Anatomoclinical study of 1 case].
Topics: Arthritis, Rheumatoid; Autoantibodies; Autoimmune Diseases; Female; Humans; Middle Aged; Myasthenia | 1976 |
[Basis of immunosuppressive effect of D-penecillamine].
Topics: Antibody Formation; Autoimmune Diseases; Humans; Immunity, Cellular; Immunosuppression Therapy; Immu | 1975 |
[Letter: Myasthenia and autoimmune thyroiditis during rheumatoid polyarthritis treated by D-penicillamine].
Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Female; Humans; Middle Aged; Myasthenia Gravis; Penicill | 1975 |
[Pemphigus induced by D-penicillamine in rheumatoid arthritis. Study of 5 cases and systematic study of anti-intercellular substance antibodies of the skin in the course of treatment].
Topics: Adult; Arthritis, Rheumatoid; Autoantibodies; Autoimmune Diseases; Female; Humans; Pemphigus; Penici | 1975 |
[Proteinuria in immunopathological diseases during long-term penicillamine therapy (author's transl)].
Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Humans; Penicillamine; Proteinuria; Scleroderma, Systemi | 1976 |
Autoimmune insulin syndrome in a patient with progressive systemic sclerosis receiving penicillamine.
Topics: Adult; Autoantibodies; Autoimmune Diseases; Blood Glucose; Humans; Insulin; Male; Penicillamine | 1992 |
D-penicillamine-induced autoimmunity in Brown-Norway rats. Similarities with HgCl2-induced autoimmunity.
Topics: Animals; Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; Autoimmune Diseases; CD8 A | 1990 |
[Analysis of cardiolipin antibodies should be done before penicillamine treatment].
Topics: Autoantibodies; Autoimmune Diseases; Cardiolipins; Humans; Penicillamine; Thromboembolism | 1989 |
Induction of anticentromere antibody in patients receiving treatment with D-penicillamine.
Topics: Adult; Aged; Antibodies, Antinuclear; Arthritis, Rheumatoid; Autoantibodies; Autoimmune Diseases; Ce | 1989 |
Kinetics of immune deposits in membranous nephropathy.
Topics: Adult; Animals; Autoimmune Diseases; Disease Models, Animal; Glomerulonephritis; Glomerulonephritis, | 1989 |
[A fatal drug-induced autoimmune syndrome].
Topics: Aged; Autoimmune Diseases; Brain; Humans; Lung; Male; Penicillamine; Radiography; Shock; Syndrome; T | 1989 |
Type II collagen induced arthritis in rats: clinical and immunological studies.
Topics: Animals; Anti-Inflammatory Agents; Antigen-Antibody Complex; Arthritis, Rheumatoid; Autoimmune Disea | 1985 |
[D-penicillamine: mechanism of cellular action and induced autoimmune diseases].
Topics: Animals; Anti-Glomerular Basement Membrane Disease; Autoimmune Diseases; Dermatomyositis; Humans; Lu | 1986 |
[Immunotropic therapy of rheumatoid arthritis (prerequisites, results and principles)].
Topics: Adrenal Cortex Hormones; Antilymphocyte Serum; Arthritis, Rheumatoid; Autoimmune Diseases; Humans; I | 1988 |
Minimal change nephropathy and pemphigus vulgaris associated with penicillamine treatment of rheumatoid arthritis.
Topics: Acute Kidney Injury; Arthritis, Rheumatoid; Autoimmune Diseases; Humans; Kidney Tubular Necrosis, Ac | 1988 |
Antiskeletal muscle antibodies during treatment with penicillamine.
Topics: Autoantibodies; Autoimmune Diseases; Enzyme-Linked Immunosorbent Assay; Humans; Muscles; Penicillami | 1987 |
[Immunosuppressive therapy in hematology].
Topics: Adrenal Cortex Hormones; Adult; Anemia, Aplastic; Anemia, Hemolytic, Autoimmune; Anemia, Myelophthis | 1972 |
Polymyositis and penicillamine.
Topics: Adult; Autoimmune Diseases; Diagnosis, Differential; Female; Hepatolenticular Degeneration; Homozygo | 1972 |
Cryoglobulinemia and disease.
Topics: Adult; Anemia, Hemolytic; Arthritis, Rheumatoid; Autoantibodies; Autoimmune Diseases; Beta-Globulins | 1970 |
[Letter: Therapy of Reiter's syndrome].
Topics: Adult; Arthritis, Reactive; Autoimmune Diseases; Humans; Male; Penicillamine | 1974 |
[Penicillamine-induced polymyositis (author's transl)].
Topics: Aged; Antibodies; Antibodies, Antinuclear; Arthritis, Rheumatoid; Autoimmune Diseases; Collagen; Cor | 1974 |
[Autoaggression diseases of the lung].
Topics: Antibody Formation; Autoantibodies; Autoimmune Diseases; Azathioprine; Cortisone; Humans; Lung Disea | 1972 |
[Long term and permanent therapy of chronic hepatitis].
Topics: Autoimmune Diseases; Chronic Disease; Cortisone; Cyclophosphamide; Female; Hepatitis; Hepatitis A; H | 1970 |
[Use of D-penicillamine in the therapy of autoimmune hemopathies with macromolecular antibodies].
Topics: Antibodies; Autoimmune Diseases; Blood Protein Disorders; Cold Temperature; Cryoglobulins; Humans; M | 1970 |