penicillamine has been researched along with Atrophy in 10 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
Atrophy: Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Atrophy of the exocrine pancreas was induced in rats by feeding a copper-deficient diet combined with penicillamine." | 7.67 | The effect of pancreatic acinar atrophy upon the concentration of vasoactive intestinal polypeptide, substance P, somatostatin and glucagon in the pancreas and gastrointestinal tract of the rat. ( Ballmann, M; Conlon, JM; Fölsch, UR, 1985) |
| "A 2 1/4 year-old boy was treated for cystinuria and urolithiasis with high fluid intake, sodium bicarbonate, and D-penicillamine, over a period of 5 3/4 years, unauthorized interruptions and prescribed pauses included." | 7.66 | Skin and bone lesions (dermato-osteolathyrism), possible side effects of D-penicillamine treatment, in a boy with cystinuria. ( Gitzelmann, R; Otten, A; Steinmann, B, 1979) |
| "Atrophy of the exocrine pancreas was induced in rats by feeding a copper-deficient diet combined with penicillamine." | 3.67 | The effect of pancreatic acinar atrophy upon the concentration of vasoactive intestinal polypeptide, substance P, somatostatin and glucagon in the pancreas and gastrointestinal tract of the rat. ( Ballmann, M; Conlon, JM; Fölsch, UR, 1985) |
| "Intestinal adaptation has been studied in rats with pancreatic atrophy induced by feeding a copper-deficient diet and penicillamine and in rats with carbohydrate maldigestion induced by feeding of an alpha-glucosidase inhibitor (acarbose)." | 3.67 | Adaptation of the small intestine to induced maldigestion in rats. Experimental pancreatic atrophy and acarbose feeding. ( Ballmann, M; Conlon, JM; Creutzfeldt, W; Elsenhans, B; Fölsch, UR, 1985) |
| "A 2 1/4 year-old boy was treated for cystinuria and urolithiasis with high fluid intake, sodium bicarbonate, and D-penicillamine, over a period of 5 3/4 years, unauthorized interruptions and prescribed pauses included." | 3.66 | Skin and bone lesions (dermato-osteolathyrism), possible side effects of D-penicillamine treatment, in a boy with cystinuria. ( Gitzelmann, R; Otten, A; Steinmann, B, 1979) |
| "Congenital localized scleroderma is a rare and probably underestimated condition in neonates." | 1.33 | Congenital localized scleroderma. ( Da Dalt, L; de Oliveira, SK; Eichenfield, LF; Galea, P; Mazur-Zielinska, H; Punaro, MG; Ros, J; Vallongo, C; Zulian, F, 2006) |
| "The progression of Wilson disease (WD), a disorder of copper metabolism, can be arrested by chelation therapy." | 1.32 | Clinical correlation of brain MRI and MRS abnormalities in patients with Wilson disease. ( Davie, CA; Lees, AJ; MacManus, D; Miller, DH; Miszkiel, KA; Page, RA; Schapira, AH; Walshe, JM, 2004) |
| "Renal function study revealed incomplete proximal renal tubular acidosis." | 1.29 | Recurrent hypokalemic muscle weakness as an initial manifestation of Wilson's disease. ( Chu, CC; Chu, NS; Huang, CC, 1996) |
| "A student was diagnosed as having Wilson's disease only after the severe, intermittent inability to open his eyes led him to seek neurologic evaluation." | 1.27 | Lid-opening apraxia in Wilson's disease. ( Keane, JR, 1988) |
| "Sixty patients with Wilson's disease have been studied by means of computerized cranial tomography (CT)." | 1.26 | Wilson's disease. An analysis of the cranial computerized tomographic appearances found in 60 patients and the changes in response to treatment with chelating agents. ( Walshe, JM; Williams, FJ, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (70.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Page, RA | 1 |
| Davie, CA | 1 |
| MacManus, D | 1 |
| Miszkiel, KA | 1 |
| Walshe, JM | 2 |
| Miller, DH | 1 |
| Lees, AJ | 1 |
| Schapira, AH | 1 |
| Zulian, F | 1 |
| Vallongo, C | 1 |
| de Oliveira, SK | 1 |
| Punaro, MG | 1 |
| Ros, J | 1 |
| Mazur-Zielinska, H | 1 |
| Galea, P | 1 |
| Da Dalt, L | 1 |
| Eichenfield, LF | 1 |
| Mihály, A | 1 |
| Pór, I | 1 |
| Bencze, G | 1 |
| Csillik, B | 1 |
| Smith, PA | 1 |
| Sunter, JP | 1 |
| Case, RM | 1 |
| Williams, FJ | 1 |
| Chu, CC | 1 |
| Huang, CC | 1 |
| Chu, NS | 1 |
| Steinmann, B | 1 |
| Otten, A | 1 |
| Gitzelmann, R | 1 |
| Ballmann, M | 2 |
| Fölsch, UR | 2 |
| Conlon, JM | 2 |
| Keane, JR | 1 |
| Creutzfeldt, W | 1 |
| Elsenhans, B | 1 |
10 other studies available for penicillamine and Atrophy
| Article | Year |
|---|---|
Clinical correlation of brain MRI and MRS abnormalities in patients with Wilson disease.
Topics: Adult; Aged; Aspartic Acid; Atrophy; Brain; Brain Chemistry; Chelation Therapy; Copper; Dipeptides; | 2004 |
Congenital localized scleroderma.
Topics: Atrophy; Biopsy; Chelating Agents; Child, Preschool; Female; Follow-Up Studies; Humans; Immunosuppre | 2006 |
Effects of perineurally applied cytostatic, cytotoxic and chelating agents upon peripheral and central processes of primary nociceptive neurons.
Topics: Action Potentials; Animals; Antineoplastic Agents; Atrophy; Azathioprine; Chelating Agents; Cyclopho | 1980 |
Progressive atrophy of pancreatic acinar tissue in rats fed a copper-deficient diet supplemented with D-penicillamine or triethylene tetramine: morphological and physiological studies.
Topics: Animals; Atrophy; Copper; Ethylenediamines; Male; Organ Size; Pancreas; Penicillamine; Rats; Rats, I | 1982 |
Wilson's disease. An analysis of the cranial computerized tomographic appearances found in 60 patients and the changes in response to treatment with chelating agents.
Topics: Adolescent; Adult; Atrophy; Brain; Cerebral Ventricles; Child; Dilatation, Pathologic; Ethylenediami | 1981 |
Recurrent hypokalemic muscle weakness as an initial manifestation of Wilson's disease.
Topics: Acidosis, Renal Tubular; Adolescent; Atrophy; Brain; Chelating Agents; Hepatolenticular Degeneration | 1996 |
Skin and bone lesions (dermato-osteolathyrism), possible side effects of D-penicillamine treatment, in a boy with cystinuria.
Topics: Atrophy; Bicarbonates; Bone and Bones; Bone Diseases; Child, Preschool; Cystinuria; Drug Eruptions; | 1979 |
The effect of pancreatic acinar atrophy upon the concentration of vasoactive intestinal polypeptide, substance P, somatostatin and glucagon in the pancreas and gastrointestinal tract of the rat.
Topics: Animals; Atrophy; Copper; Digestive System; Duodenum; Gastric Mucosa; Glucagon; Ileum; Jejunum; Male | 1985 |
Lid-opening apraxia in Wilson's disease.
Topics: Adult; Apraxias; Atrophy; Brain; Cerebellum; Eyelid Diseases; Hepatolenticular Degeneration; Humans; | 1988 |
Adaptation of the small intestine to induced maldigestion in rats. Experimental pancreatic atrophy and acarbose feeding.
Topics: Acarbose; Adaptation, Physiological; alpha-Glucosidases; Animals; Atrophy; Cholecystokinin; Copper; | 1985 |