penicillamine has been researched along with Arthritis, Rheumatoid in 1283 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To optimize treatment for rheumatoid arthritis (RA) and to define indications for D-penicillamine and methotrexate therapies on an individual basis by taking into account the levels of rheumatoid factor (RF) isotopes circulating in blood." | 9.09 | [Efficacy of D-penicillamine and methotrexate in the treatment of rheumatoid arthritis in relation to levels of circulating rheumatoid factors of different classes]. ( Derevianko, LI; Sivordova, LE; Zavodovskiĭ, BV; Zborovskaia, IA; Zborovskiĭ, AB, 1999) |
| "To compare the efficacy of hydroxychloroquine, penicillamine, sodium aurothiomalate and auranofin in the treatment of active rheumatoid arthritis over a period of 5 yr." | 9.08 | A long-term five-year randomized controlled trial of hydroxychloroquine, sodium aurothiomalate, auranofin and penicillamine in the treatment of patients with rheumatoid arthritis. ( Camilleri, JP; Coles, EC; Jessop, JD; Lewis, PA; O'Sullivan, MM; Plant, MJ; Williams, LA, 1998) |
| "We studied the effects of D-penicillamine (DP) on the clinical response, immunoinflammatory parameters and the lymphocyte subsets in 46 patients with rheumatoid arthritis (RA)." | 9.07 | Effect of D-penicillamine on lymphocyte subsets: correlation with clinical response in rheumatoid arthritis. ( Beri, D; Khare, SD; Kumar, A; Malaviya, AN; Malaviya, R; Mehra, NK; Shandilya, R; Sharma, M; Singh, RR; Taneja, V, 1994) |
| "Thiopronin is a second line drug for rheumatoid arthritis with proven efficacy in controlled trials versus a placebo, D-penicillamine, or gold salts." | 9.07 | [A comparative controlled trial of 2 administration modalities of tiopronin in rheumatoid arthritis]. ( Brin, S; Combe, B; Delecoeuillerie, G; Paolozzi, L; Sany, J, 1993) |
| "Ninety-two patients with active rheumatoid arthritis (RA) were entered in a randomized double blind study of 24 weeks comparing cyclosporine (initial daily dose 5 mg/kg) with D-penicillamine (initial daily dose 250 mg)." | 9.07 | Comparison of cyclosporine and D-penicillamine for rheumatoid arthritis: a randomized, double blind, multicenter study. ( Boers, M; Cats, A; Dijkmans, BA; Meijers, KA; Montnor-Beckers, ZL; Moolenburgh, JD; Thè, HS; van Rijthoven, AW, 1991) |
| "An attempt was made to audit the clinical usefulness of sulphasalazine and penicillamine in patients with rheumatoid arthritis (RA) managed in a routine out-patient setting with assistance from general practitioners and to ascertain whether clinically significant differences can be shown between these two 'second-line' agents." | 9.06 | Degree and extent of response to sulphasalazine or penicillamine therapy for rheumatoid arthritis: results from a routine clinical environment over a two-year period. ( Capell, HA; Hunter, JA; Madhok, R; Marabani, M; Torley, H, 1990) |
| "To assess whether monthly treatment with intravenous methylprednisolone enhances or accelerates the effect of disease modifying drugs in patients with rheumatoid arthritis." | 9.06 | Double blind placebo controlled trial of pulse treatment with methylprednisolone combined with disease modifying drugs in rheumatoid arthritis. ( Elling, H; Haar, D; Hansen, TM; Ingeman-Nielsen, MW; Kreutzfeldt, M; Kryger, P; Olsson, AT; Pedersen, C; Rahbek, A; Tvede, N, 1990) |
| "Forty patients with active rheumatoid arthritis were included in this monocentre double-blind study comparing the therapeutic efficacy and safety of the immunomodulator OM-8980 with that of D-penicillamine." | 9.06 | OM-8980 and D-penicillamine in the treatment of rheumatoid arthritis. A 12-month double-blind randomized study. ( Dequeker, J; Sileghem, A; Verstraeten, A, 1990) |
| "Fifty-four patients with rheumatoid arthritis were randomized to either sulphasalazine or D-penicillamine in order to compare the short- and long-term efficacy of these two agents in the treatment of rheumatoid arthritis." | 9.06 | Sulphasalazine versus penicillamine in the treatment of rheumatoid arthritis. ( Breidahl, PD; Carroll, GJ; Tinsley, LM; Will, RK, 1989) |
| "The pharmacokinetic effect of the combined treatment of penicillamine with indomethacin and chloroquine was investigated in patients with rheumatoid arthritis." | 9.06 | Pharmacokinetic interactions of penicillamine in rheumatoid arthritis. ( Lindström, B; Seideman, P, 1989) |
| "Seventy-three patients with early, active rheumatoid arthritis (RA) were randomly allocated either to a group that received penicillamine or to a control group from which penicillamine was barred, any other second-line drug being permitted." | 9.06 | A prospective five-year comparison of treatment which included penicillamine with that excluding penicillamine in early rheumatoid arthritis. The Multicentre Trial Group. ( , 1986) |
| "Twenty-six out-patients with active rheumatoid arthritis (RA) were randomly allocated to treatment with sulphasalazine (SASP) or D-penicillamine (DPA)." | 9.06 | Effects of sulphasalazine on faecal flora in patients with rheumatoid arthritis: a comparison with penicillamine. ( Cooke, EM; Neumann, VC; Shinebaum, R; Wright, V, 1987) |
| " An open trial of SA 96 treatment (300 mg/day after meals for 16 weeks) was carried out in 11 patients with definite or classical rheumatoid arthritis and with therapeutic failure of previous gold salts and/or D-penicillamine therapy." | 9.06 | SA 96 (N-(2-mercapto-2-methylpropanoyl)-L-cysteine) in rheumatoid arthritis. ( Ishikawa, K; Sakaguchi, M, 1986) |
| "After a controlled, double blind multicenter trial of D-penicillamine in the treatment of rheumatoid arthritis, 148 patients were followed for an additional year in an open label trial." | 9.06 | Toxicity of longterm low dose D-penicillamine therapy in rheumatoid arthritis. Cooperative Systematic Studies of Rheumatic Disease Group. ( , 1987) |
| "Forty patients with definite or classical active rheumatoid arthritis were stratified by the minimization procedure to auranofin (6 mg/day) or penicillamine (go slow and low regime)." | 9.06 | Auranofin versus penicillamine in rheumatoid arthritis. One-year results from a prospective clinical investigation. ( Hørbov, S; Manthorpe, R; Sylvest, J; Vinterberg, H, 1986) |
| "Ninety patients were entered into a randomized, controlled, double-blind trial lasting 12 months to compare auranofin (6 mg/d), and D-penicillamine (250 mg/d for 4 weeks, 500 mg/d for 4 weeks, then 750 mg/d thereafter) in the treatment of rheumatoid arthritis." | 9.06 | Auranofin or D-penicillamine in the treatment of rheumatoid arthritis. ( Hochberg, MC, 1986) |
| "Thirty patients with rheumatoid arthritis were allocated to either methylprednisolone pulse therapy or placebo at the beginning of treatment with either gold salts, penicillamine, or azathioprine." | 9.06 | Combination of methylprednisolone pulse therapy and remission inducing drugs in rheumatoid arthritis. ( Dickmeiss, E; Hansen, TM; Ingeman-Nielsen, M; Ingemann Hansen, T; Jans, H; Lorenzen, I, 1987) |
| "Seventy-two patients with relatively early but progressive rheumatoid arthritis were treated with chloroquine sulphate, D-penicillamine or a combination of both drugs over 1 year." | 9.06 | Combined D-penicillamine and chloroquine treatment of rheumatoid arthritis--a comparative study. ( Armstrong, RD; Crisp, AJ; Emery, P; Gibson, T; Panayi, GS, 1987) |
| "The induction of antinuclear antibodies (ANA) by D-penicillamine (DP) was studied in 148 patients with rheumatoid arthritis (RA) who had completed at least 30 weeks in a double blind trial which compared DP at doses 500 mg and 125 mg daily to placebo." | 9.06 | Lack of induction of antinuclear antibodies by D-penicillamine in rheumatoid arthritis: a controlled study. ( Rothfield, NF; Weinstein, A, 1986) |
| "Seventy two patients with classical or definite rheumatoid arthritis (RA) were randomly allocated to receive gold or D-penicillamine therapy (DPA) in a prospective study designed to evaluate whether it is possible to predict which patients will show radiological progression despite therapy." | 9.06 | Prediction of progressive joint damage in patients with rheumatoid arthritis receiving gold or D-penicillamine therapy. ( Collins, M; Dawes, PT; Fowler, PD; Jackson, R; Scott, DL; Shadforth, MF; Stone, R, 1986) |
| "One hundred patients with active rheumatoid arthritis, uncontrolled by symptom relieving agents, were allocated randomly to intramuscular gold or oral penicillamine therapy." | 9.06 | General practitioner assistance with gold and penicillamine therapy of rheumatoid arthritis--a four year prospective study. ( Capell, HA; Hunter, JA; Madhok, R; Pullar, T, 1987) |
| "Two hundred twenty-five patients with active severe rheumatoid arthritis were admitted to a multiclinic, controlled, double-blind trial comparing the use of 500 mg D-penicillamine per day, 125 mg D-penicillamine per day, and placebo." | 9.05 | Low-dose D-penicillamine therapy in rheumatoid arthritis. A controlled, double-blind clinical trial. ( Cathcart, ES; Egger, MJ; Furst, DE; Grandone, JT; Guttadauria, M; Halla, JT; Kaplan, SB; Plotz, PH; Reading, JC; Samuelson, CO; Sullivan, JM; Ward, JR; Watson, MA; Weinstein, A; Williams, HJ, 1983) |
| "A 2-year, controlled, double-blind trial of D-penicillamine and hydroxychloroquine either alone or in combination was conducted on patients with progressive rheumatoid arthritis." | 9.05 | Controlled trial of hydroxychloroquine and D-penicillamine singly and in combination in the treatment of rheumatoid arthritis. ( Bunch, TW; O'Duffy, JD; O'Fallon, WM; Tompkins, RB, 1984) |
| "Thirty-eight patients with rheumatoid arthritis in remission on penicillamine were entered into a prospective, randomised, placebo controlled study to determine the effects of gradual penicillamine withdrawal, to find a serological marker capable of predicting relapse, and to assess the effects of reintroduction of penicillamine." | 9.05 | D-penicillamine withdrawal in rheumatoid arthritis. ( Ahern, MJ; Case, K; Hall, ND; Maddison, PJ, 1984) |
| "The oral gold salt auranofin, 6 mg per day, was compared with oral d-penicillamine, 500 mg per day, in a single-blind trial in 40 patients suffering with definite or classic rheumatoid arthritis." | 9.05 | A 12-month comparative trial of auranofin and D-penicillamine in rheumatoid arthritis. ( Bateman, JR; Delamere, JP; Felix-Davies, DD; Stewart, AM; Wilkinson, BR, 1983) |
| "Forty-six patients with classical or definite rheumatoid arthritis participated in a prospective clinical trial comparing auranofin 6 mg/day (26 patients) with D-penicillamine 500 mg/day (20 patients) during one year." | 9.05 | Auranofin and D-penicillamine: a one year comparative study of safety and efficacy in patients with rheumatoid arthritis followed by a two year open assessment of auranofin. ( Franchimont, P; Hauwaert, C; Vanschoubroek, K, 1984) |
| "Levamisole (150 mg once weekly) was compared with penicillamine (250 mg daily) in a single blind independent observer study in 28 patients with rheumatoid arthritis over twelve months." | 9.05 | A comparison of low dose levamisole and penicillamine in rheumatoid arthritis. ( Ansell, BM; Bernstein, RM; Clemens, LE; Hall, MA; McCauley, D, 1983) |
| "Twelve patients with rheumatoid arthritis who had failed to respond to or developed side effects preventing further use of penicillamine were given 5-thiopyridoxine (5-TP)." | 9.05 | 5-Thiopyridoxine in rheumatoid arthritis: clinical and experimental studies. ( Dieppe, PA; Huskisson, EC; Jaffe, IA; Scott, J, 1980) |
| "The medical records of our first 200 consecutive rheumatoid arthritis patients treated with penicillamine were analyzed retrospectively." | 9.05 | Clinical trial of penicillamine in rheumatoid arthritis. ( Bergen, W; Phillips, VK; Rothermich, NO; Thomas, MH, 1981) |
| "Pulsed methylprednisolone (PMP) has been shown to produce clinical improvement and reduction in the ESR and acute phase protein concentrations in patients with active rheumatoid arthritis and has been advocated for use either as an alternative to slow-acting antirheumatoid drugs (SAARDs) or in conjunction with SAARDs to accelerate the response to treatment." | 9.05 | Combination therapy with pulsed methylprednisolone in rheumatoid arthritis. ( Bird, H; Dixon, J; Hopkins, R; Neumann, V; Watkins, A; Wright, V, 1985) |
| "The authors studied and compared the action of chlorbutin, azathioprin, of large and mean doses of D-penicillamine and levamisole with that of nonsteroidal antiinflammatory drugs (NAID) on rheumatoid arthritis systemic manifestations in 186 patients treated with these drugs for more than 3 months." | 9.05 | [Chlorbutin, azathioprine, D-penicillamine and levamisole (decaris) in the treatment of patients with rheumatoid arthritis. IV. Comparative evaluation of their effects on systemic (extra-articular) manifestations of the disease]. ( Chichasova, NV; Kanevskaia, MZ; Khamishon, LZ; Krel', AA; Nemchenov, EN, 1985) |
| "Forty-six patients with rheumatoid arthritis, 22 receiving D-penicillamine and 2j alclofenac, took part in a 6-month single-bind external observer trial to compare the efficacy and toxicity of these drugs in the treatment of severe rheumatoid arthritis." | 9.04 | Alclofenac and D-penicillamine. Comparative trial in rheumatoid arthritis. ( Berry, H; Evans, SJ; Fernandes, L; Ford-Hutchinson, AW; Hamilton, EB, 1978) |
| "In a controlled study involving thirty-four patients levamisole was shown to be as effective as D-penicillamine and more effective than placebo in the treatment of rheumatoid arthritis." | 9.04 | Immunostimulant therapy with levamisole for rheumatoid arthritis. ( Balme, HW; Dieppe, PA; Huskisson, EC; Scott, J; Trapnell, J; Willoughby, DA, 1976) |
| "In a series of 100 adult patients with definite rheumatoid arthritis of at most 3 years' duration and with no previous penicillamine, gold or systemic corticosteroid treatment, 50 patients were treated with D-penicillamine and 50 with gold for one yar." | 9.04 | Comparison of penicillamine and gold treatment in early rheumatoid arthritis. ( Anttila, P; Kajander, A; Mäkisara, GL; Mäkisara, P; Martio, J; Nissilä, M; von Essen, R, 1978) |
| "Alclofenac and D-penicillamine were compared under controlled, double-blind conditions in the treatment of 35 patients with active rheumatoid arthritis over a period of 26 weeks." | 9.04 | The influence of alclofenac treatment on acute-phase proteins, plasma tryptophan, and erythrocyte sedimentation rate in patients with rheumatoid arthritis. ( Aylward, M; Holly, F; Maddock, J; Rees, P, 1975) |
| "Reports of 28 authors with a total of nearly 1,000 enrolled patients have been reviewed regarding changes in clinical manifestations of disease in rheumatoid arthritis during short term and long term administration of levamisole." | 9.04 | International symposium on levamisole in rheumatoid arthritis. A review of short and longterm effects on articular manifestations. ( Basch, CM; Engleman, EP; Spitler, LE, 1978) |
| "The use of penicillamine in the treatment of rheumatoid arthritis and scheroderma is reviewed." | 9.04 | The use of penicillamine in the treatment of rheumatoid arthritis and scleroderma. ( Baum, J, 1979) |
| "Doses of 600 mg and 1200 mg of D(-)penicillamine daily were superior to a standard regimen of therapy in rheumatoid arthritis." | 9.04 | Synthetic D(-)penicillamine in rheumatoid arthritis. Double-blind controlled study of a high and low dosage regimen. ( Davies, J; Dixon, AJ; Dormandy, TL; Hamilton, EB; Holt, PJ; Mason, RM; Thompson, M; Weber, JC; Zutshi, DW, 1975) |
| "Sixty-five patients, 33 receiving azathioprine and 32 receiving penicillamine, took part in a one-year, single-blind external-observer trial designed to compare the efficacy and toxicity of these two drugs in the treatment of rheumatoid arthritis." | 9.04 | Azathioprine and penicillamine in treatment of rheumatoid arthritis: a controlled trial. ( Barnes, CG; Berger, LA; Berry, H; Durance, RA; Evans, S; Liyanage, SP, 1976) |
| "In a controlled trial including 80 patients suffering from different stages of rheumatoid arthritis it was demonstrated that D-penicillamine therapy favourably influences the clinical course of the disease as compared to a control group treated with antirheumatic drugs." | 9.04 | [Long term treatment of rheumatoid arthritis. Experiences with D-penicillamine in comparison with gold and immunosuppressive drugs (author's transl)]. ( Gutmann, W; Scheiffarth, F; Warnatz, H, 1975) |
| "To estimate the short-term effects of D-penicillamine for the treatment of rheumatoid arthritis (RA)." | 8.80 | Penicillamine for rheumatoid arthritis. ( Belseck, E; Spooner, C; Suarez-Almazor, ME, 2000) |
| "To estimate the short-term effects of D-penicillamine for the treatment of rheumatoid arthritis (RA)." | 8.80 | Penicillamine for treating rheumatoid arthritis. ( Belseck, E; Spooner, C; Suarez-Almazor, ME, 2000) |
| "To perform a cost effectiveness analysis of cyclosporine (CyA) in the treatment of rheumatoid arthritis (RA)." | 8.79 | A cost effectiveness analysis of cyclosporine in rheumatoid arthritis. ( Anis, AH; Stewart, DG; Tugwell, PX; Wells, GA, 1996) |
| "Between 1979 and 1990 we have seen 8 patients (7 females) with rheumatoid arthritis (RA) who developed a neuro-muscular involvement while on D-penicillamine (D." | 8.78 | [Neuromuscular complications of D-penicillamine in rheumatoid arthritis]. ( Bouchet, F; Bussière, JL; Dubost, JJ; Kemeny, JL; Lhopitaux, R; Sauvezie, B; Soubrier, M, 1992) |
| "We have encountered a 53 year-old female with myasthenia gravis (MG) possibly induced by the treatment with D-penicillamine (D-pc)." | 8.78 | [D-penicillamine induced myasthenia gravis in a patient with rheumatoid arthritis]. ( Hosoya, T; Kuriyama, S; Sakai, O, 1991) |
| "A patient with severe rheumatoid arthritis received d-penicillamine treatment for 16 months." | 8.78 | D-penicillamine induced pemphigus treated with methylprednisolone pulse therapy. ( De Clerck, LS; Francx, L; Stevens, WJ; Wouters, EA, 1990) |
| "Pemphigus erythematosus occurred in a patient with rheumatoid arthritis who was treated with D-penicillamine." | 8.78 | Penicillamine-induced pemphigus erythematosus. ( De Coninck, AL; De Raeve, LE; Roseeuw, DI; Willemsen, MJ, 1990) |
| "In the present study, the side effects of d-Penicillamine therapy in 54 patients with rheumatoid arthritis are analyzed." | 8.77 | [Side effects of d-penicillamine in the treatment of rheumatoid arthritis]. ( Bianchini, D; Cataldo, R; Damiani, D; Florean, M; Mazzanti, G; Mesesnel, E; Paladini, G, 1986) |
| "Three cases of penicillamine induced pemphigus are described and compared to 35 previously reported cases with typical direct immunofluorescence." | 8.77 | Penicillamine induced pemphigus. ( Ho, VC; McLeod, WA; Ongley, RA; Stein, HB, 1985) |
| "A review of the literature on the longterm use of methotrexate in patients with rheumatoid arthritis (RA) showed that many questions on protocol remain unanswered." | 8.77 | Longterm methotrexate therapy in rheumatoid arthritis: a review. ( Kremer, JM, 1985) |
| "The use of penicillamine in rheumatoid arthritis (RA) is limited by the incidence of adverse effects, some of which are potentially hazardous." | 8.76 | Penicillamine in rheumatoid arthritis: adverse effects. ( Hill, HF, 1979) |
| "A 63-year-old woman had D-penicillamine-induced pemphigus with a high index value of circulating autoantibodies against desmoglein 1." | 7.72 | D-penicillamine-induced pemphigus successfully treated with combination therapy of mizoribine and prednisolone. ( Hirokawa, H; Izu, K; Sugita, K; Tokura, Y, 2004) |
| "In this study we report our two years experience of methotrexate (MTX) in the management of rheumatoid arthritis (RA) at the Aga Khan University Hospital, Karachi." | 7.70 | Methotrexate in rheumatoid arthritis: a 2 year experience at a university hospital in Pakistan. ( Ali, AA; Beg, JA; Hussain, MA; Iqbal, MP; Mehboobali, N; Rahbar, MH, 1998) |
| "To investigate whether the therapeutic response of rheumatoid arthritis (RA) patients to D-penicillamine is associated with polymorphisms in genes of the glutathione S-transferase (GST) supergene family." | 7.70 | The therapeutic response to D-penicillamine in rheumatoid arthritis: influence of glutathione S-transferase polymorphisms. ( Alldersea, JE; Dawes, PT; Fryer, AA; Jones, PW; Layton, MA; Mattey, DL; Strange, RC, 1999) |
| "A 67-year old woman who had been taking D-penicillamine for 15 months for rheumatoid arthritis was hospitalized due to the development of a bullous eruption and proximal muscle deficiency." | 7.70 | [D-penicillamine-induced pemphigus, polymyositis and myasthenia]. ( Callens, A; Jan, V; Lorette, G; Machet, L; Machet, MC; Vaillant, L, 1999) |
| "We present here a case of MPO-ANCA positive rapidly progressive glomerulonephritis (RPGN) after 34 months of D-penicillamine (D-PC) therapy for rheumatoid arthritis (RA)." | 7.70 | [MPO-ANCA positive rapidly progressive glomerulonephritis in a patient with rheumatoid arthritis during treatment with D-penicillamine]. ( Akama, H; Hara, M; Kamatani, N; Nanke, Y; Terai, C, 1999) |
| "We present 3 cases of anti-myeloperoxidase, anti-neutrophil cytoplasmic antibody (MPO-ANCA)-positive rapidly progressive glomerulonephritis developed during the treatment with D-penicillamine (D-PC) for rheumatoid arthritis." | 7.70 | Rapidly progressive glomerulonephritis with D-penicillamine. ( Akama, H; Kamatani, N; Nanke, Y; Terai, C, 2000) |
| "Five patients out of 71 with rheumatoid arthritis (RA), who received D-penicillamine, developed myasthenia gravis (MG) within a two-year period." | 7.69 | D-penicillamine induced myasthenia gravis in rheumatoid arthritis: an unpredictable common occurrence? ( Andonopoulos, AP; Papapetropoulos, T; Papasteriades, CA; Terzis, E; Tsibri, E, 1994) |
| "Myasthenia gravis may be observed due to treatment with penicillamine (D-PA)." | 7.69 | Reduced sulphoxidation capacity in D-penicillamine induced myasthenia gravis. ( Ayesh, R; Seideman, P, 1994) |
| "D-penicillamine, a drug used to treat rheumatoid arthritis, Wilson's disease, and cystinuria, can cause myasthenia gravis." | 7.69 | D-penicillamine-induced myasthenia gravis: diagnosis obscured by coexisting chronic obstructive pulmonary disease. ( Adelman, HM; Mahan, CS; Wallach, PM; Winters, PR, 1995) |
| "We describe a 63-year-old female patient with rheumatoid arthritis who developed complete heart block and features of polymyositis within a few weeks of starting treatment with D-penicillamine." | 7.69 | D-penicillamine induced polymyositis causing complete heart block. ( Bell, AL; Wilson, C; Wright, GD, 1994) |
| "D-penicillamine has been used in the treatment of rheumatoid arthritis for years." | 7.69 | [D-penicillamine-induced myasthenia gravis]. ( Frey, RA; Keller, F; Michel, BA, 1994) |
| "A 53-year-old woman with rheumatoid arthritis developed myasthenia gravis after 6 months of therapy with D-penicillamine." | 7.69 | D-penicillamine and gold salt treatments were complicated by myasthenia and pemphigus, respectively, in the same patient with rheumatoid arthritis. ( Agelli, M; Bazzichi, L; Ciompi, ML; Marchetti, G; Puccetti, L, 1995) |
| " During treatment with D-penicillamine the patient developed a transient lupus-like disorder with glomerulonephritis that resolved when D-penicillamine was discontinued." | 7.69 | C1 inhibitor deficiency in a patient with rheumatoid arthritis--increased risk of adverse effects of penicillamine? ( Alm, P; Rydgren, L; Sjöholm, AG; Sturfelt, G; Truedsson, L, 1996) |
| "D-penicillamine, an agent still used in the treatment of rheumatoid arthritis (RA) may produce inflammatory myopathy or myositis." | 7.69 | D-penicillamine-induced myositis in rheumatoid arthritis. ( Chappel, R; Willems, J, 1996) |
| " Both patients (one case of progressive systemic sclerosis and one of rheumatoid arthritis) were currently taking D-penicillamine." | 7.68 | Unilateral ptosis as an initial manifestation of D-penicillamine induced myasthenia gravis. ( Fries, JF; Kornfeld, P; Lee, YS; Raynauld, JP, 1993) |
| "A 57-yr-old lady developed polymyositis whilst taking D-penicillamine for RA." | 7.68 | D-penicillamine and polymyositis: the significance of the anti-Jo-1 antibody. ( Hull, RG; Jenkins, EA; Thomas, AL, 1993) |
| "A 67-year-old woman with rheumatoid arthritis presented rapidly progressive glomerulonephritis (RPGN) after 5 months of D-penicillamine (250 mg/day) treatment." | 7.68 | Penicillamine-induced rapidly progressive glomerulonephritis in a patient with rheumatoid arthritis. ( Alcorta, I; Almirall, J; Botey, A; Revert, L, 1993) |
| "We report the case of an 80-year-old woman who developed pemphigus foliaceus while taking penicillamine for rheumatoid arthritis." | 7.68 | [Pemphigus foliaceus caused by penicillamine]. ( Burg, G; Burger, M; Hartmann, AA; Zentner, A; Zillikens, D, 1993) |
| "A 55-year-old woman with advanced rheumatoid arthritis developed rapidly progressive glomerulonephritis with epithelial crescents and pulmonary hemorrhage following treatment with D-penicillamine." | 7.68 | D-penicillamine therapy associated with rapidly progressive glomerulonephritis. ( Azofra, JA; Fernandez, G; García Díaz, JE; Gonzalez, E; Macarrón, P; Martín de Francisco, J; Sampedro, J, 1992) |
| "Nine cases of penicillamine induced pemphigus (PIP) in rheumatoid arthritis patients are reported." | 7.68 | HLA system and penicillamine induced pemphigus in nine cases of rheumatoid arthritis. ( Bauer-Vinassac, D; Escande, JP; Menkes, CJ; Muller, JY, 1992) |
| "Spin echo NMR analysis is used to monitor the effect of penicillamine on intact erythrocytes obtained from patients suffering from rheumatoid arthritis during a 12-week period of therapy." | 7.68 | Clinical analysis by 1H spin-echo NMR. 2. Oxidation of intracellular glutathione as a consequence of penicillamine therapy in rheumatoid arthritis. ( Brzeski, M; Marabani, M; Reglinski, J; Smith, WE; Sturrock, RD, 1992) |
| "To determine if a policy of continuing penicillamine therapy in successfully treated patients with rheumatoid arthritis in the presence of persistent proteinuria, was associated or not with resolution of this adverse effect, a computer record of patients receiving penicillamine for rheumatoid arthritis was searched for patients with persistent proteinuria and the case notes of these patients reviewed." | 7.68 | Management of proteinuria secondary to penicillamine therapy in rheumatoid arthritis. ( DeSilva, RN; Eastmond, CJ, 1992) |
| "A female patient with IgM RF seropositive rheumatoid arthritis according to criteria of the American Rheumatism Association was treated for 133 months with Penicillamine and for 17 months also with Sulfasalazine." | 7.68 | [Rheumatoid arthritis developing into systemic lupus erythematosus during long-term treatment with penicillamine and sulfasalazine]. ( Hrncír, Z; Pintérová, E; Rejchrt, S, 1991) |
| "C4 null alleles and HLA-DR antigens were defined in 48 rheumatoid arthritis (RA) subjects who had developed renal or heamatological side effects to gold or penicillamine, as compared to 33 RA subjects who had received the drugs for similar time periods without developing side effects." | 7.68 | Complement C4 null alleles as a marker of gold or D-penicillamine toxicity in the treatment of rheumatoid arthritis. ( Clarkson, RW; Grennan, DM; Sanders, PA, 1992) |
| "Sixty-two consecutive patients, with rheumatoid arthritis (RA) who received D-penicillamine were studied retrospectively to identify predictive risk factors for D-penicillamine toxicity." | 7.68 | D-penicillamine toxicity in Greek patients with rheumatoid arthritis: anti-Ro(SSA) antibodies and cryoglobulinemia are predictive factors. ( Drosos, AA; Moutsopoulos, HM; Skopouli, FN; Vlachoyiannopoulos, PG; Zerva, LV, 1991) |
| "A 40 year old woman with rheumatoid arthritis developed pure red cell aplasia after treatment with D-penicillamine 500 mg/day." | 7.68 | Pure red cell aplasia caused by D-penicillamine treatment of rheumatoid arthritis. ( Kahn, Y; Tishler, M; Yaron, M, 1991) |
| "The distribution of autoantibodies was studied in patients with rheumatoid arthritis (RA) treated by D-penicillamine and who developed myasthenia gravis (MG)." | 7.68 | Autoantibodies in D-penicillamine-induced myasthenia gravis: a comparison with idiopathic myasthenia and rheumatoid arthritis. ( Bach, JF; Bataille, R; D'Anglejan, J; Feuillet-Fieux, MN; Morel, E; Raimond, F; Sany, J; Vernet-der Garabedian, B, 1991) |
| "After considering the cutaneous side effects of D-penicillamine in rheumatoid arthritis management, a few cases of cutaneous adverse reaction observed in 5 (13%) of 38 patients, who received the drugs, are described." | 7.68 | [Cutaneous side effects induced by D-penicillamine in the treatment of rheumatoid arthritis]. ( Baratelli, E; Broggini, M; Cappelli, A; Crespi, E; Filardi, PG; Volontè, S, 1990) |
| "We report a case of a 47-year-old woman with rheumatoid arthritis who developed ocular myasthenia gravis during penicillamine treatment." | 7.68 | Penicillamine-induced ocular myasthenia gravis in rheumatoid arthritis. ( Bienfang, DC; Liu, GT, 1990) |
| "We report a retrospective study of 16 patients with seropositive rheumatoid arthritis who were placed on combination D-penicillamine and methotrexate therapy for a period of 5-86 months." | 7.68 | Combination D-penicillamine and methotrexate therapy: proposal for early and aggressive treatment for rheumatoid arthritis. ( Lee, S; Solomon, G, 1990) |
| " The plasma pharmacokinetics of D-penicillamine (D-pen) and D-penicillamine-albumin disulphide (D-pen-alb) were examined over a dosage interval in six patients with rheumatoid arthritis." | 7.68 | D-penicillamine and D-penicillamine-protein disulphide in plasma and synovial fluid of patients with rheumatoid arthritis. ( Day, RO; Joyce, DA, 1990) |
| "The outcome of attempts to continue treatment indefinitely with either gold, penicillamine, sulphasalazine, or dapsone was studied in 240 patients with rheumatoid arthritis (RA)." | 7.67 | Outcome of attempts to treat rheumatoid arthritis with gold, penicillamine, sulphasalazine, or dapsone. ( Grindulis, KA; McConkey, B, 1984) |
| "The long term efficacy and tolerability of sulphasalazine (SASP) in the treatment of 21 patients with active classical or definite rheumatoid arthritis (RA) were examined and compared with the effects of penicillamine in a similarly active group of RA patients." | 7.67 | The long term effects of sulphasalazine in the treatment of rheumatoid arthritis and a comparative study with penicillamine. ( Bacon, PA; Crockson, AP; Farr, M; Tunn, E, 1984) |
| "Optic neuropathy developed in a patient with rheumatoid arthritis who had been receiving D-penicillamine for about 1 year." | 7.67 | Optic neuropathy associated with penicillamine therapy in a patient with rheumatoid arthritis. ( Burde, RM; Klingele, TG, 1984) |
| "The concentration of selenium in serum (S-Se) was studied in 20 patients and glutathione in erythrocytes (E-GSH) in 16 patients with rheumatoid arthritis (RA) at onset and after 3 and 6 months of antirheumatic therapy with aurothiomalate (19 cases) or with D-penicillamine (one case)." | 7.67 | Glutathione and selenium in rheumatoid arthritis. ( Alfthan, G; Hannonen, P; Möttönen, T; Oka, M; Seppälä, O, 1984) |
| "Prospective and retrospective analysis of data obtained on 119 patients with rheumatoid arthritis suggested a relationship between clinical response induced by gold salts or D-penicillamine and decreased in vitro antibody synthesis by peripheral blood mononuclear cells." | 7.67 | Decreased pokeweed mitogen-induced IgM and IgM rheumatoid factor synthesis in rheumatoid arthritis patients treated with gold sodium thiomalate or penicillamine. ( Jasin, HE; Olsen, NJ, 1984) |
| "One hundred sixty-eight patients with rheumatoid arthritis treated with chloroquine (n = 87), gold salts (n = 133) and/or penicillamine (n = 77) were investigated for possible associations between HLA antigens and toxic reactions." | 7.67 | HLA antigens and toxicity to gold and penicillamine in rheumatoid arthritis. ( Kolarz, G; Mayr, WR; Mayrhofer, F; Scherak, O; Smolen, JS; Thumb, NJ, 1984) |
| "We studied patients with rheumatoid arthritis who have been treated with aurothioglucose (Au) and subsequently with D-penicillamine (DP), and who developed drug-induced proteinuria, over a 10-year period." | 7.67 | The relationship between aurothioglucose- and D-penicillamine-induced proteinuria. ( Rasker, JJ; Reekers, P; Speerstra, F; van de Putte, LB; Vandenbroucke, JP, 1984) |
| "Natural killer (NK) activity against K 562 target cells was studied in 60 patients with definite or classic rheumatoid arthritis (RA), grouped by medication into 1) Controls not in remission-inducing therapy, 2) Patients treated with penicillamine, and 3) Patients treated with azathioprine." | 7.67 | Azathioprine as single drug in the treatment of rheumatoid arthritis induces complete suppression of natural killer cell activity. ( Beyer, JM; Helin, P; Hørslev-Petersen, K; Klarlund, K; Pedersen, BK; Pedersen, BN; Rasmussen, A, 1984) |
| "After administration of D-penicillamine to patients with rheumatoid arthritis, measurements of serum level and urinary excretion showed half-life times of 1." | 7.67 | D-penicillamine in patients with rheumatoid arthritis. Serum levels, pharmacokinetic aspects, and correlation with clinical course and side effects. ( Ament, HJ; Henrichs, AM; Muijsers, AO; van de Stadt, RJ; van der Korst, JK, 1984) |
| "The prevalence of eosinophilia in 66 patients with rheumatoid arthritis receiving D-penicillamine was determined in a retrospective study." | 7.67 | Eosinophilia in rheumatoid patients treated with D-penicillamine. ( Edelman, J; Maguire, KF; Owen, ET, 1984) |
| "Plasma concentrations were measured in 10 patients with rheumatoid arthritis taking 250 mg, 500 mg and 750 mg of D-penicillamine daily." | 7.67 | Dose, plasma concentration and response relationships of D-penicillamine in patients with rheumatoid arthritis. ( Birkett, DJ; Brooks, PM; Fearnley, I; Miners, JO; Smith, K; Smith, MD, 1984) |
| "Large differences exist in the maintenance doses of penicillamine that clinicians regard as effective and safe in rheumatoid arthritis." | 7.67 | Clinical response in relation to dose of penicillamine in the treatment of rheumatoid arthritis. ( Lyle, WH, 1984) |
| "During the period 1976-1983, 67 patients with rheumatoid arthritis attending the arthritis clinics at Groote Schuur Hospital and Princess Alice Orthopaedic Hospital, Cape Town, were treated with penicillamine." | 7.67 | Penicillamine therapy in rheumatoid arthritis. ( Grobbelaar, J; Meyers, OL, 1984) |
| "The pharmacokinetic disposition of D-penicillamine and its major metabolites, penicillamine cysteine disulfide ( PSSC ) and penicillamine disulfide ( PSSP ) has been studied in eight patients with rheumatoid arthritis." | 7.67 | Pharmacokinetics of the major metabolites of D-penicillamine in patients with rheumatoid arthritis. ( Butler, M; Carruthers, G; Freeman, D; Harth, M; Rothwell, R; Weir, D, 1984) |
| "Complexes formed between penicillamine and metal ions have in vitro effects that may have implications regarding the therapeutic action of D-penicillamine in rheumatoid arthritis." | 7.67 | Penicillamine metal chelates and their possible importance in rheumatoid arthritis--a brief review. ( Davis, P, 1984) |
| "Penicillamine treatment of rheumatoid arthritis was compared with gold and other remittive agents by reviewing the literature and studying the patients in our penicillamine clinic with respect to their previous responses to chrysotherapy." | 7.67 | Penicillamine and other remittive agents in rheumatoid arthritis: comparisons and interaction. ( Atkins, CJ; Offer, RC; Ruedy, J; Stein, HB, 1984) |
| "Seven of 56 consecutive patients taking penicillamine for rheumatoid arthritis developed oral lesions that clinically and histologically resembled lichen planus." | 7.67 | Lichenoid lesions of the oral mucosa in rheumatoid arthritis patients treated with penicillamine. ( Blasberg, B; Chalmers, A; Conklin, RJ; Dorey, JL; Stein, HB, 1984) |
| "The mechanism of D-penicillamine induced thrombocytopenia in rheumatoid arthritis was investigated by measuring platelet life-span and platelet production rate in 2 groups of rheumatoid arthritis patients treated with 250-750 mg/day D-penicillamine, 14 with a normal platelet count and 9 with thrombocytopenia (platelet count 50-130 X 10(9)/1)." | 7.67 | Thrombokinetics in patients with rheumatoid arthritis treated with D-penicillamine. ( Brooks, PM; Gallus, AS; Geddes, R; Hill, W; Tampi, R; Thomas, D, 1984) |
| "A small fraction of patients with rheumatoid arthritis and other diseases on D-penicillamine treatment may develop antibodies against the acetylcholine receptor (AChR) and symptoms of myasthenia gravis (MG)." | 7.67 | Fine antigenic specificities of antibodies in sera from patients with D-penicillamine-induced myasthenia gravis. ( Bustarret, AF; D'Anglejan, J; Drosos, AA; Efthimiadis, A; Morel, E; Moutsopoulos, HA; Tzartos, SJ, 1988) |
| "Complete heart block with severe Adams-Stokes attacks and polymyositis was observed in a 69-year-old man following 6 weeks penicillamine treatment for suspected rheumatoid arthritis." | 7.67 | Penicillamine-induced polymyositis with complete heart block. ( Christensen, PD; Sørensen, KE, 1989) |
| "A rheumatoid arthritis case is described who developed bullous skin eruption with mucosal involvement after 3 years of treatment with penicillamine." | 7.67 | Penicillamine-induced bullous pemphigoid with pemphigus-like antibodies. ( Brandrup, F; Jepsen, LV; Rasmussen, HB, 1989) |
| "A 65 year old woman with rheumatoid arthritis developed marrow aplasia and jaundice owing to D-penicillamine treatment." | 7.67 | Fatal aplastic anaemia and liver toxicity caused by D-penicillamine treatment of rheumatoid arthritis. ( Caspi, D; Fishel, B; Tishler, M; Yaron, M, 1989) |
| "A patient on treatment with D-penicillamine developed aphthoid ulcers of the oesophagus, which healed rapidly after withdrawal of this drug." | 7.67 | D-penicillamine-induced oesophageal ulcers. ( Ramboer, C; Verhamme, M, 1989) |
| "Thirty patients (22 women) with active rheumatoid arthritis participated in an open study of 6 months' treatment with either enteric-coated sulphasalazine (SASP) or SASP plus D-penicillamine (DPA)." | 7.67 | Sulphasalazine alone or in combination with D-penicillamine in rheumatoid arthritis. ( Astbury, C; Bird, HA; Dixon, JS; Hill, J; Taggart, AJ; Wright, V, 1987) |
| "Life-table analysis was applied to the records of 317 patients with rheumatoid arthritis (RA) treated with sulphasalazine (SAS), 201 treated with sodium aurothiomalate (gold), and 163 with penicillamine." | 7.67 | Long-term treatment of rheumatoid arthritis with sulphasalazine, gold, or penicillamine: a comparison using life-table methods. ( Grindulis, KA; McConkey, B; Situnayake, RD, 1987) |
| "Forty-two patients with active rheumatoid arthritis treated with hydroxychloroquine sulphate (400 mg day-1) for six months have been compared with patients treated with D-penicillamine (n = 14), aurothiomalate (n = 13), sulphasalazine (n = 15) and chloroquine (n = 17) to compare the changes in articular index, plasma viscosity and ESR." | 7.67 | How reliable is ESR as a measure of disease activity in rheumatoid arthritis treated with hydroxychloroquine? ( Bird, HA; Dixon, JS; Greenwood, M, 1988) |
| "A 57-year-old patient with rheumatoid arthritis, who was being treated with D-penicillamine, developed a bullous eruption 2 months after the onset of treatment." | 7.67 | [Pemphigus herpetiformis following D-penicillamine in a patient with HLA B8]. ( David, M; Ingber, A; Sandbank, M; Weltfriend, S, 1988) |
| "The mechanism by which D-Penicillamine is effective in the treatment of rheumatoid arthritis has been investigated." | 7.67 | Suggested mode of action of D-penicillamine as an immunosuppressive agent in rheumatoid arthritis. ( Lipsky, PE, 1988) |
| "The capacity of monocytes from patients with rheumatoid arthritis to generate superoxide anion in vitro after stimulation with serum treated zymosan (STZ) or IgG treated zymosan (IgTZ) was studied before and during therapy with penicillamine (n = 9) or sodium aurothiomalate (AuTM) (n = 12)." | 7.67 | Studies of the effect of D-penicillamine and sodium aurothiomalate therapy on superoxide anion production by monocytes from patients with rheumatoid arthritis: evidence for in vivo stimulation of monocytes. ( Bell, AL; Hurst, NP; Nuki, G, 1986) |
| "The acetylator phenotype was determined in 59 patients with classical, seropositive and erosive rheumatoid arthritis (RA) treated with sodium-aurothiomalate or d-penicillamine." | 7.67 | Acetylator phenotypes in rheumatoid arthritis patients with or without adverse drug reactions to sodium-aurothiomalate or d-penicillamine. ( Mjörndal, T; Rantapää Dahlqvist, S, 1987) |
| "The effects of long-term aurothiomalate and D-penicillamine treatments on renal function and the urinary excretion of prostanoids were studied in 20 patients with classic or definite rheumatoid arthritis." | 7.67 | Effects of long-term aurothiomalate and D-penicillamine treatments on renal function and urinary excretion of prostanoids in patients with rheumatoid arthritis. ( Harmoinen, A; Isomäki, H; Koivula, T; Lehtinen, K; Mörsky, P; Nissilä, M; Seppälä, E; Vapaatalo, H, 1988) |
| " proteinuria, haematological abnormalities, stomatitis, diarrhoea and dermatitis) in rheumatoid arthritis (RA) to sodium aurothiomalate (gold) and to D-penicillamine (PA) were studied in 32 patients." | 7.67 | HLA antigens and adverse drug reactions to sodium aurothiomalate and D-penicillamine in patients with rheumatoid arthritis. ( Bjelle, A; Dahlqvist, SR; Möller, E; Ström, H, 1985) |
| "Progressive joint damage characterises rheumatoid arthritis despite treatment with slow-acting drugs such as penicillamine." | 7.67 | Progressive joint damage during penicillamine therapy for rheumatoid arthritis. ( Bryans, R; Greenwood, A; Huskisson, EC; Scott, DL, 1988) |
| "A 41-year-old woman with rheumatoid arthritis developed massive breast enlargement while taking penicillamine." | 7.67 | Penicillamine induced mammary hyperplasia: report of a case and review of the literature. ( Craig, HR, 1988) |
| " In 27 patients with rheumatoid arthritis, we measured the pulmonary excretion of pentane, a product released during lipid peroxidation." | 7.67 | Breath pentane excretion as a marker of disease activity in rheumatoid arthritis. ( Clapper, M; Humad, S; Skosey, JL; Zarling, E, 1988) |
| "The effects of piroxicam and D-penicillamine on T lymphocytes, NK cell activity and rheumatoid factor production as well as clinical parameters were studied in patients with rheumatoid arthritis." | 7.67 | Effects of piroxicam and D-penicillamine on T lymphocyte subpopulations, natural killer cells and rheumatoid factor production in rheumatoid arthritis. ( Førre, O; Haile, Y; Helgetveit, K; Kåss, E; Thoen, J, 1988) |
| "D-Penicillamine is effective in the treatment of Wilson's disease, cystinuria and rheumatoid arthritis." | 7.67 | [Penicillamine-induced pemphigus]. ( Gleichmann, E; Goerz, G; Kind, P; Plewig, G, 1987) |
| "Free and total reduced concentrations of D-penicillamine have been measured in the plasma of rheumatoid arthritis patients by HPLC and electro-chemical detection." | 7.67 | Identification of factors limiting the accurate measurement of plasma D-penicillamine in rheumatoid arthritis patients. ( Haslock, I; Richardson, SJ; Webb, BA, 1988) |
| "A 51-year-old man developed pemphigus vulgaris, minimal change nephropathy and acute tubular necrosis after 11 months of treatment with penicillamine for rheumatoid arthritis associated with features of Reiter's syndrome." | 7.67 | Minimal change nephropathy and pemphigus vulgaris associated with penicillamine treatment of rheumatoid arthritis. ( Chia, Y; Pusey, CD; Savill, JS, 1988) |
| "To assess therapeutic effect and toxicity of D-penicillamine in relation to HLA antigens, 111 consecutive patients with rheumatoid arthritis (RA) were followed for a period of 7-9 years." | 7.67 | Longterm followup of treatment with D-penicillamine for rheumatoid arthritis: effectivity and toxicity in relation to HLA antigens. ( Ament, BJ; Feltkamp, BW; Moens, HJ; van der Korst, JK, 1987) |
| "In a 3-centre study involving 144 patients with rheumatoid arthritis (RA), a relationship between side effects from D-penicillamine and HLA antigens, allotypic markers of the IgG heavy chain (Gm) and allotypes of complement components Bf, C4A and C4B was sought." | 7.67 | Genetic markers in rheumatoid arthritis relationship to toxicity from D-penicillamine. ( Hannah, MC; Major, GA; Mathews, JD; McCluskey, J; Muirden, KD; Property, DN; Stockman, A; Tait, BD; Zilko, PJ, 1986) |
| "Twenty-six of 300 patients (9%) with rheumatoid arthritis (RA) developed penicillamine-induced proteinuria." | 7.67 | Penicillamine-induced proteinuria: risk factors. ( Dillon, AM; Schroeder, ML; Stein, HB, 1986) |
| "Eight Australian cases of D-penicillamine induced polymyositis/dermatomyositis (PM/DM) are reported." | 7.67 | Penicillamine induced polymyositis and dermatomyositis. ( Carroll, GJ; Dawkins, RL; Garlepp, MJ; Peter, JB; Will, RK, 1987) |
| "Among 329 patients with rheumatoid arthritis treated with D-penicillamine (DP), we found 4 cases of polymyositis." | 7.67 | D-penicillamine-induced polymyositis in patients with rheumatoid arthritis. ( Miyamoto, T; Ogita, T; Okudaira, H; Takahashi, K; Yoshinoya, S; Yoshizawa, H, 1986) |
| "We have described three patients whose rheumatoid arthritis was exacerbated by penicillamine." | 7.67 | Penicillamine-induced exacerbation of rheumatoid arthritis. ( Butler, D; Tiliakos, NA, 1986) |
| "D-penicillamine and its major metabolites cysteine-penicillamine disulphide (CP) and penicillamine disulphide (P2) concentrations were measured in plasma from a hemodialysis patient with rheumatoid arthritis." | 7.67 | The use of D-penicillamine in patients with rheumatoid arthritis undergoing hemodialysis. ( Baker, LR; Greenwood, RN; Matthey, F; Perrett, D, 1986) |
| "We have described a unique patient who had reversible and dose-related myasthenia gravis after penicillamine and chloroquine therapy for rheumatoid arthritis." | 7.67 | Myasthenia gravis caused by penicillamine and chloroquine therapy for rheumatoid arthritis. ( Hearn, J; Tiliakos, NA, 1986) |
| "The case of a 57-year-old woman with rheumatoid arthritis is presented to illustrate the rare occurrence of a myasthenic syndrome induced by D-penicillamine, which led to prolonged (5." | 7.67 | D-penicillamine induced myasthenia gravis. Its relevance for the anaesthetist. ( Fried, MJ; Protheroe, DT, 1986) |
| "A 68 year old man with rheumatoid arthritis developed marrow aplasia during D-penicillamine treatment." | 7.67 | Acquired sideroblastic anaemia after aplastic anaemia caused by D-penicillamine therapy for rheumatoid arthritis. ( Bijlsma, JW; Dekker, AW; Huber-Bruning, O; Ramselaar, AC, 1987) |
| "One hundred and forty-one patients with rheumatoid arthritis treated with aurothiopropanol sulphonate or D-penicillamine, or both were examined for HLA antigens to investigate the genetic influence on the occurrence of different adverse reactions during therapy." | 7.67 | HLA antigens and toxic reactions to sodium aurothiopropanol sulphonate and D-penicillamine in patients with rheumatoid arthritis. ( Busson, M; Gaucher, A; Perrier, P; Raffoux, C; Streiff, F; Tamisier, JN; Thomas, P, 1985) |
| "HLA phenotype frequencies were studied in 21 rheumatoid arthritis (RA) patients with haematotoxic reactions to aurothioglucose (AuTG) or D-penicillamine (DP), 65 matched RA controls and 277 healthy controls." | 7.67 | HLA associations in aurothioglucose- and D-penicillamine-induced haematotoxic reactions in rheumatoid arthritis. ( Reekers, P; Speerstra, F; van de Putte, LB; Vandenbroucke, JP, 1985) |
| "A patient developed both ankylosing spondylitis and rheumatoid arthritis, each of which responded to D-penicillamine or gold sodium thiomalate and indomethacin, respectively." | 7.67 | Ankylosing spondylitis and rheumatoid arthritis in a patient with Paget's disease. Differential effects of indomethacin, D-penicillamine, or gold sodium thiomalate in the respective arthritides. ( Alarcón-Segovia, D; Martínez-Cordero, E, 1985) |
| "Long-term therapy of D-penicillamine (D-Pen) for rheumatoid arthritis (RA) is associated with a fall in rheumatoid factor, but many patients develop autoantibodies." | 7.67 | Increased binding of D-penicillamine to monocytes in rheumatoid arthritis. ( Dawkins, RL; Grimsley, G; Major, GA; Watanabe, H, 1986) |
| "A 49 year old man with rheumatoid arthritis developed a proliferative glomerulonephritis with progressive renal impairment during treatment with D-penicillamine." | 7.67 | Progressive proliferative glomerulonephritis in a patient with rheumatoid arthritis treated with D-penicillamine. ( Barnes, CG; Fordham, JN; Goodwin, FJ; Williams, AJ, 1986) |
| "A male aged 72 years suffering from erosive seropositive rheumatoid arthritis developed jaundice after one month on D-penicillamine after a cumulative dose of 5." | 7.67 | A case of cholestatic hepatitis associated with D-penicillamine therapy for rheumatoid arthritis. ( Coche, E; Devogelaer, JP; Huaux, JP; Nagant de Deuxchaisnes, C; Rahier, J, 1985) |
| "A patient with advanced rheumatoid arthritis and severe clinical manifestations of rheumatoid vasculitis died of acute renal failure after 30 months of treatment with high-dosage D-penicillamine." | 7.67 | Rapidly progressive glomerulonephritis in a patient with rheumatoid arthritis during treatment with high-dosage D-penicillamine. ( Berger, AR; Milstoc, M; Sadjadi, SA; Seelig, MS, 1985) |
| "Three cases of D-penicillamine (DPA) induced myasthenia gravis (MG) and one case of DPA-induced polymyositis (PM) are reported among four patients suffering from seropositive rheumatoid arthritis." | 7.67 | Neuromuscular disorders associated with D-penicillamine treatment for rheumatoid arthritis. ( De Bruyère, M; Devogelaer, JP; Huaux, JP; Isaac, G; Nagant de Deuxchaisnes, C; Noël, H, 1985) |
| "A patient receiving d-penicillamine for rheumatoid arthritis developed a lymphoma, therapy for which resulted not only in haematological resolution but marked remission of rheumatoid disease activity, including radiological improvement." | 7.67 | Remission of arthritis and radiological improvement after combination therapy for non-Hodgkin's lymphoma in a patient with rheumatoid arthritis undergoing treatment with D-penicillamine. ( Sheldon, P; Wood, JK, 1985) |
| "In view of the claim that alclofenac has a specific antirheumatoid action a detailed biochemical study has been made over a 6-month period of 2 groups of patients with rheumatoid arthritis receiving either alclofenac or D-penicillamine for the first time." | 7.66 | A biochemical comparison of alclofenac and D-penicillamine in rheumatoid arthritis. ( Bird, HA; Dixon, JS; Lee, MR; Pickup, ME; Wright, V, 1980) |
| "Cross-sectional and longitudinal studies have been carried out to determine the incidence and clinical significance of eosinophilia in patients taking penicillamine for rheumatoid arthritis." | 7.66 | Eosinophilia in D-penicillamine therapy. ( Scott, DL; Smith, DH; Zaphiropoulos, GC, 1983) |
| "Ninety patients with rheumatoid arthritis who had received courses of gold followed by penicillamine for their disease were evaluated to determine the predictiveness of a certain response or adverse reaction to gold for the same response or adverse reaction to penicillamine." | 7.66 | Sequential gold and penicillamine therapy in rheumatoid arthritis. ( Cassady, J; Halla, JT; Hardin, JG, 1982) |
| "One hundred fourteen patients with definite or classic rheumatoid arthritis were followed prospectively between January 1976 and April 1981 to monitor their toxicity pattern to D-penicillamine." | 7.66 | Prior gold therapy does not influence the adverse effects of D-penicillamine in rheumatoid arthritis. ( Buchanan, WW; Howard-Lock, HE; Kean, WF; Lock, CJ, 1982) |
| "Skin rashes, proteinuria, systemic lupus erythematosus, polymyositis and myasthenia gravis have all been recorded as complications of penicillamine therapy in patients with rheumatoid arthritis." | 7.66 | Multiple side effects of penicillamine therapy in one patient with rheumatoid arthritis. ( Essigman, WK, 1982) |
| "Electroneuromyographic studies have been reported as abnormal in only 9 of 23 cases of penicillamine-associated myasthenia gravis (MG)." | 7.66 | Penicillamine-associated myasthenia gravis. ( Albers, JW; Hodach, RJ; Kimmel, DW; Treacy, WL, 1980) |
| "Electroneuromyographic studies were performed on patients with rheumatoid arthritis, some of whom were received penicillamine, to determine whether a subclinical defect of neuromuscular transmission existed." | 7.66 | Neuromuscular transmission in rheumatoid arthritis, with and without penicillamine treatment. ( Albers, JW; Beals, CA; Levine, SP, 1981) |
| "Rapidly progressive glomerulonephritis occurred in a woman with rheumatoid arthritis (RA) who had been treated with D-penicillamine for 3 months." | 7.66 | Extracapillary glomerulonephritis with necrotizing vasculitis in D-penicillamine-treated rheumatoid arthritis. ( Banfi, G; Guerra, L; Imbasciati, E; Mihatsch, MJ; Ponticelli, C, 1983) |
| "Groups of 15 patients with active rheumatoid arthritis were treated for 24 weeks with zinc sulphate, trien, captopril, clozic in two doses or a combination of D-penicillamine and hydroxychloroquine." | 7.66 | The effect of drugs on serum histidine levels in rheumatoid arthritis. ( Bird, HA; Dixon, JS; Martin, MF; Pickup, ME; Sitton, NG; Surrall, KE, 1983) |
| "Antibodies to the acetylcholine receptor and HLA antigens have been studied in patients with myasthenia gravis occurring in association with penicillamine treatment." | 7.66 | HLA antigens and acetylcholine receptor antibodies in penicillamine induced myasthenia gravis. ( Christiansen, FT; Dawkins, RL; Garlepp, MJ, 1983) |
| "By means of a case-control study we investigated the association between HLA phenotypes and the development of proteinuria after aurothioglucose or D-penicillamine treatment in patients with rheumatoid arthritis (RA)." | 7.66 | HLA-DR antigens and proteinuria induced by aurothioglucose and D-penicillamine in patients with rheumatoid arthritis. ( de Rooij, DJ; Rasker, JJ; Reekers, P; Speerstra, F; van de Putte, LB; Vandenbroucke, JP, 1983) |
| "A 44-year-old woman with rheumatoid arthritis and vasculitis of the skin developed a lupus erythematosus-like reaction after 5 weeks of D-penicillamine therapy." | 7.66 | Penicillamine-induced lupus-like reaction in rheumatoid arthritis and vasculitis. ( Thorvaldsen, J, 1981) |
| "The clinical features and genetic background of 18 patients with rheumatoid arthritis were investigated following the development of penicillamine-induced myasthenia (PIM)." | 7.66 | Penicillamine-induced myasthenia in rheumatoid arthritis: its clinical and genetic features. ( Delamere, JP; Jobson, S; Mackintosh, LP; Walton, KW; Wells, L, 1983) |
| "Diffuse fasciculations developed in a patient with rheumatoid arthritis who had received D-penicillamine for 6 months." | 7.66 | Diffuse fasciculations induced by D-penicillamine. ( Pinals, RS, 1983) |
| "Over recent years, several cases have been reported of bronchiolitis obliterans, of very rapid onset and serious clinical course in patients with rheumatoid arthritis being treated with D-Penicillamine." | 7.66 | [Rheumatoid arthritis, obliterating bronchiolitis and D-penicillamine. Apropos of a new case with ultrastructural examination and review of the literature]. ( Blanc-Jouvan, F; Brambilla, E; Geraads, A; Hohn, B; Kamel, A; Piton, JL, 1983) |
| "A 69-year-old woman with classical rheumatoid arthritis developed a severe dermato-myopathy during treatment with penicillamine." | 7.66 | Penicillamine-induced dermatomyositis. A case history. ( Lund, HI; Nielsen, M, 1983) |
| "Forty-four patients with definite or classical rheumatoid arthritis were entered in a 48-week open study, comparing the long-term effects of Timegadine and D-penicillamine." | 7.66 | A comparative trial of timegadine and D-penicillamine in rheumatoid arthritis. ( Dequeker, J; Mbuyi-Muamba, JM, 1983) |
| "Thrombotic thrombocytopenic purpura (TTP) developed in a patient with seropositive rheumatoid arthritis (RA) after 2 1/2 months of treatment with penicillamine." | 7.66 | Thrombotic thrombocytopenic purpura during penicillamine therapy in rheumatoid arthritis. ( Pinals, RS; Plitman, GI; Trice, JM, 1983) |
| "To investigate the possible relation between certain HLA antigens and toxicity during treatment with sodium aurothiomalate of D-penicillamine, we studied 91 patients with rheumatoid arthritis." | 7.66 | HLA-DR antigens and toxic reaction to sodium aurothiomalate and D-penicillamine in patients with rheumatoid arthritis. ( Batchelor, JR; Gibson, TJ; Griffin, J; Panayi, GS; Welsh, KI; Wooley, PH, 1980) |
| "Myositis was diagnosed twenty months after starting treatment with d-penicillamine in a patient suffering from uncomplicated rheumatoid arthritis for nearly three years." | 7.66 | [Is myositis in chronic polyarthritis using d-penicillamine drug-induced?]. ( Bussmann, HU; Jerusalem, F; Schlumpf, U, 1981) |
| "Sixty patients with active rheumatoid arthritis (mean ESR = 51 mm/h) were treated for six months with D-penicillamine (15 patients), sodium aurothiomalate (15 patients), hydroxychloroquine (15 patients) or enteric-coated aspirin (15 patients)." | 7.66 | Enteric-coated aspirin in rheumatoid arthritis. ( Bird, HA; Leatham, P; Rhind, V; Saunders, A; Wright, V, 1981) |
| "Immunoglobulins (IgG, IgA, IgM) have been measured by radial immunodiffusion method in 43 patients affected with rheumatoid arthritis and treated with d-penicillamine (Pen)." | 7.66 | [Effect of D-penicillamine on serum immunoglobulins in rheumatoid arthritis]. ( Gambari, PF; Mioni, E; Ongaro, G; Ostuni, A; Punzi, L; Todesco, S; Volante, D, 1981) |
| "Thirteen reports of patients who developed polymyositis or dermatomyositis during treatment with D-penicillamine are reviewed and a fourteenth case is described." | 7.66 | Fatal polymyositis in D-penicillamine-treated rheumatoid arthritis. ( Doyle, DR; McCurley, TL; Sergent, JS, 1983) |
| "Penicillamine treatment of patients with rheumatoid arthritis (RA) leads to falling titers of agglutinating IgM rheumatoid factor (RF), but its effect on IgG RF has not been described." | 7.66 | IgG and IgM rheumatoid factors in rheumatoid arthritis. Quantitative response to penicillamine therapy and relationship to disease activity. ( Jaffe, I; Merryman, P; Wernick, R; Ziff, M, 1983) |
| "Four of 133 patients with rheumatoid arthritis suddenly developed progressive respiratory symptoms while receiving penicillamine therapy." | 7.66 | Upper and lower airway disease in penicillamine treated patients with rheumatoid arthritis. ( James, DL; Lin, JJ; Montgomery-Short, R; Polland, SM; Schurle, DR; Smith, TW; Wolfe, F, 1983) |
| "Six patients with rheumatoid arthritis developed a syndrome resembling lupus erythematosus while being treated with penicillamine." | 7.66 | Systemic lupus erythematosus during penicillamine therapy for rheumatoid arthritis. ( Chalmers, A; Patterson, AC; Reid, G; Stein, HE; Thompson, D, 1982) |
| "Among 67 patients with rheumatoid arthritis treated with gold salts (aurothiopropanol sulphonate) a significant correlation (p less than 10(-2)) was noted between gold toxic reactions, whatever their type, and the HLA antigens A1, B8, Cw7, and DR3." | 7.66 | HLA system and side effects of gold salts and D-penicillamine treatment of rheumatoid arthritis. ( Bardin, T; Dausset, J; Debeyre, N; Dryll, A; Legrand, L; Marcelli, A; Ryckewaert, A, 1982) |
| "Eighteen of 24 patients with rheumatoid arthritis showed intermediate IgG-containing complexes on preparative ultracentrifugation before treatment with D-penicillamine." | 7.66 | Circulating protein complexes in D-penicillamine therapy of rheumatoid arthritis. Correlation between IgG- and alpha 1-antitrypsin-IgA complexes and clinical response. ( Gedda, PO; Norberg, R; Wollheim, FA, 1980) |
| "Penicillamine-associated bullous eruptions share with spontaneously occurring pemphigus intraepidermal acantholysis, epidermal intercellular deposition of immunoglobulin, and circulating serum antibody against the intercellular regions of the epidermis." | 7.66 | Penicillamine-associated pemphigus: is it really pemphigus? ( Grossman, ME; Jaffe, IA; Silvers, DN; Troy, JL, 1981) |
| "Immunological and electrophysiological features were investigated in a patient with rheumatoid arthritis who developed myasthenic symptoms after 10 months of treatment with D-penicillamine (D-pen)." | 7.66 | D-Penicillamine-associated myasthenia gravis: immunological and electrophysiological studies. ( Argov, Z; Fawcett, PR; Mastaglia, FL; McLachlan, SM; Nicholson, LV, 1982) |
| "Fifty-seven patients took part in a controlled double-blind trial between tiopronin and D-penicillamine as basic treatment for rheumatoid arthritis." | 7.66 | Controlled multicenter trial of tiopronin and d-penicillamine for rheumatoid arthritis. ( Ambanelli, U; Barbieri, P; Ciompi, ML; Colamussi, V; Ferraccioli, G; Mazzoni, MR; Menegale, G; Pasero, G; Pellegrini, P; Trippi, D, 1982) |
| "Twenty-five patients with rheumatoid arthritis treated with D-penicillamine were retrospectively reviewed for signs of drug intolerance." | 7.66 | The relationship between D-penicillamine--induced proteinuria and prior gold nephropathy. ( Billingsley, LM; Stevens, MB, 1981) |
| "The development of pemphigus foliaceus in three patients and pemphigus erythematosus in one patient with rheumatoid arthritis treated with penicillamine is described." | 7.66 | Pemphigus in rheumatoid arthritis treated with penicillamine. ( Livden, JK; Milde, EJ; Naevdal, A, 1981) |
| "The authors report on 2 personal cases, and review 48 published cases of myasthenia induced by D-penicillamine (D-P) treatment in patients with rheumatoid arthritis." | 7.66 | [D-penicillamine induced myasthenic syndromes in rheumatoid arthritis. Two cases (author's transl)]. ( Cler, JM; Cottin, S; Hamelin, JP; Lemouroux, P; Rodat, G; Rodat, O; Rossard, A, 1981) |
| "The action of D-penicillamine on collagen can cause undesired side-effects in the treatment of cystinuria and Wilson's disease, it is on the other hand essential to the therapy of rheumatoid arthritis and scleroderma." | 7.66 | D-penicillamine in pregnancy--to ban or not to ban? ( Endres, W, 1981) |
| "This article reports some observations made in a woman who developed myasthenia gravis after treatment with D-penicillamine." | 7.66 | Penicillamine-induced myasthenia gravis in a patient with rheumatoid arthritis. A case report. ( Naidoo, PD, 1981) |
| "Adverse effects to D-penicillamine were studied prospectively over 3 years in 259 patients with rheumatoid arthritis." | 7.66 | Adverse effects of D-penicillamine in rheumatoid arthritis. ( Atkins, CJ; Offer, RC; Patterson, AC; Robinson, HS; Stein, HB; Teufel, A, 1980) |
| "One hundred and one patients with rheumatoid arthritis were followed prospectively to assess the efficacy and toxicity of therapy with D-penicillamine." | 7.66 | The toxicity pattern of D-penicillamine therapy. A guide to its use in rheumatoid arthritis. ( Anastassiades, TP; Dwosh, IL; Ford, PM; Kean, WF; Kelly, HG, 1980) |
| "The authors describe a new original observation of a D-penicillamine-induced pemphigus in a patient with rheumatoid polyarthritis." | 7.66 | [D-penicillamine-induced pemphigus]. ( Bathias, J; Chouvet, B; Forestier, JY; Thivolet, J, 1980) |
| "Out of 64 patients with rheumatoid arthritis (RA), 42 were treated with D-penicillamine (D-Pa) for more than 6 months and 22 for less than 6 months." | 7.66 | Penicillamine treatment in rheumatoid arthritis. A retrospective study. ( Börjesson, O; Knutsson, LP; Svensson, B, 1980) |
| "A study of patients with rheumatoid arthritis permitted us to note the interest of tiopronine (sulfhydryl compound of the d-penicillamine type) in the basic treatment of rheumatoid arthritis." | 7.66 | [Tiopronine: new basic treatment for rheumatoid arthritis. Open study of 158 cases]. ( Barbieri, P; Ciompi, ML; Colamussi, V; Mazzoni, MR; Pasero, G; Pellegrini, P, 1980) |
| "Two patients with rheumatoid arthritis developed evidence of hepatotoxicity while receiving D-penicillamine." | 7.66 | Hepatotoxicity associated with use of D-penicillamine in rheumatoid arthritis. ( Katz, WA; Rosenbaum, J; Schumacher, HR, 1980) |
| "Following one-week treatment with D-penicillamine for rheumatoid arthritis a seven-year-old girl died with the clinical features of protracted circulatory shock." | 7.66 | [Administration of D-penicillamine instead of penicillin with fatal results: allergy of the delayed type with protracted shock as fatal complication of treatment with D-penicillamine for rheumatoid arthritis in a child (author's transl)]. ( Adebahr, G; Erkrath, KD; Klöppel, A, 1980) |
| "A case of dermatomyositis is reported in a 50-year-old woman receiving D-Penicillamine therapy for rheumatoid arthritis." | 7.66 | Dermatomyositis induced by penicillamine. ( Golding, JR; Simpson, NB, 1979) |
| "Although in common use, there is still controversy as to the way in which gold and penicillamine act in rheumatoid arthritis (RA)." | 7.66 | Gold and penicillamine: a proposed mode of action in rheumatoid arthritis, based on synovial fluid analysis. ( Nuki, G; Pritchard, MH, 1978) |
| "2 women, 62 and 69 years old, both suffering from rheumatoid arthritis, were treated for 1 and 1 1/2 years, respectively, with penicillamine." | 7.66 | Two cases of penicillamine-induced pemphigus erythematosus. ( Thorvaldsen, J, 1979) |
| "Liver enzymes were followed in 99 patients treated with D-penicillamine for rheumatoid arthritis." | 7.66 | Liver abnormalities in penicillamine treated rheumatoid arthritis. ( Lindström, CG; Wollheim, FA, 1979) |
| "The difficulties encountered in administering D-penicillamine to 40 patients with rheumatoid arthritis (RA) over a six to 24 month period are recorded." | 7.66 | Difficulties in the use of D-penicillamine in the treatment of rheumatoid arthritis. ( Barraclough, D; Kincaid-Smith, P; Macdonald, I; Muirden, KD; Richter, D; Stockman, A, 1979) |
| "28 patients with rheumatoid arthritis undergoing treatment with penicillamine were investigated over a period of 7 to 72 months." | 7.66 | [Are antinuclear factors a contraindication for penicillamine treatment in patients with rheumatoid arthritis? (author's transl)]. ( Hiesberger, H; Kolarz, G; Scherak, O, 1978) |
| "D-Penicillamine treatment in rheumatoid arthritis resulted in a fall in plasma alfa-1-antitrypsin-IgA complexes which was significantly more pronounced among responders than among non-responders." | 7.66 | D-penicillamine treatment in rheumatoid arthritis monitored by plasma alfa-1-antitrypsin-IgA complexes and plasma and urinary sulphur containing aminoacids. ( Jeppsson, JO; Laurell, CB; Wollheim, FA, 1979) |
| "Collagen biosynthesis was measured in skin biopsies taken from 13 patients with rheumatoid arthritis before and after at least 6 months' continuous treatment with D-penicillamine, 1." | 7.66 | Skin collagen biosynthesis in patients with rheumatoid arthritis treated with D-penicillamine. ( Francis, MJ; Loudon, M; Mowat, AG; Schorn, D, 1979) |
| "Penicillamine has been successfully reintroduced and continued for a minimum of 13 months in 5 patients who developed proteinuria during the first course of the drug." | 7.66 | Resumption of treatment with penicillamine after proteinuria. ( Davison, AM; Hill, A; Hill, H, 1979) |
| "There is much individual variation in the response of rheumatoid arthritis (RA) to penicillamine, some patients deriving benefit from very small doses." | 7.66 | Maintenance dose of penicillamine in rheumatoid arthritis: a comparison between a standard and a response-related flexible regimen. ( Brown, RM; Day, AT; Golding, JR; Hill, AG; Hill, HF; Lyle, WH, 1979) |
| "A woman with rheumatoid arthritis was treated with penicillamine and developed myasthenia gravis." | 7.66 | Penicillamine-induced myasthenia gravis associated with antibodies to acetylcholine receptor. ( Lindstrom, JM; Russell, AS, 1978) |
| "To assess toxicity of D-penicillamine a retrospective chart review was performed on 63 patients with rheumatoid arthritis receiving penicillamine." | 7.66 | Toxicity of D-penicillamine in rheumatoid arthritis. A report of 63 patients including two with aplastic anemia and one with the nephrotic syndrome. ( Kammerer, WH; Markenson, JA; Weiss, AS; Weiss, MS, 1978) |
| "The effect of therapeutic concentrations of D-penicillamine, sodium aurothiomalate, and levamisole on in vitro neutrophil chemotaxis and random migration in normal subjects and patients with rheumatoid arthritis was studied." | 7.66 | Neutrophil chemotaxis in rheumatoid arthritis. Effect of D-penicillamine, gold salts, and levamisole. ( Mowat, AG, 1978) |
| "Two patients with classical rheumatoid arthritis developed myopathy during treatment with penicillamine." | 7.66 | Penicillamine-induced polymyositis-dermatomyositis. ( Halberg, P; Højgaard, K; Lyon, BB; Petersen, J; Ullman, S, 1978) |
| "In patients with rheumatoid arthritis neither indomethacin nor aspirin influenced the levels of the erythrocyte sedimentation rate (e." | 7.65 | A study of the influence of various antirheumatic drug regimens on serum acute-phase proteins, plasma tryptophan, and erythrocyte sedimentation rate in rheumatoid arthritis. ( Aylward, M; Maddock, J; Parker, RJ; Wheeldon, R, 1975) |
| "A patient with arthritis is described who developed a dermatitis herpetiformis-like rash after 8 months of D-penicillamine therapy and which cleared soon after the drug was discontinued." | 7.65 | Herpetiform pemphigus induced by penicillamine. ( Dawber, RP; Marsden, RA; Millard, PR; Mowat, AG, 1977) |
| "A case of dermatomyositis developing during the course of treatment with D-penicillamine in a patient with rheumatoid arthritis is described." | 7.65 | Dermatomyositis complicating penicillamine treatment. ( Fernandes, L; Hamilton, EB; Swinson, DR, 1977) |
| "Forty-four patients with definite or classic rheumatoid arthritis and failure to tolerate or respond to gold therapy were treated with D-penicillamine on a so-called go-slow, go-low regime." | 7.65 | D-penicillamine in the treatment of rheumatoid arthritis. ( Ford, DK; Patterson, CA; Robinson, HS; Stein, HB; Tsang, IK, 1977) |
| "Myasthenia gravis with thymic hyperplasia developed in a patient with Wilson's disease after eight years of penicillamine treatment." | 7.65 | Penicillamine-associated myasthenia gravis, antiacetylcholine receptor and antistriational antibodies. ( Dawkins, RL; Leedman, RJ; Masters, CL; Simpson, JA; Zilko, PJ, 1977) |
| "A myasthenic reaction developed after an average latency of seven to eight months in 12 female patients (average age 51 years) treated with penicillamine for chronic rheumatoid arthritis." | 7.65 | [Penicillamine-induced myasthenia in chronic rheumatoid arthritis (author's transl)]. ( Hopf, HC; Janzen, RW; Meyer, W; Seitz, D, 1976) |
| "Fourteen patients who developed persistent proteinuria while on penicillamine for rheumatoid arthritis, were collected over a period of one year." | 7.65 | Penicillamine nephropathy in rheumatoid arthritis. A clinical, pathological and immunological study. ( Amer, B; Bacon, PA; Cumming, RH; Mackenzie, JC; Tribe, CR; Verrier-Jones, J, 1976) |
| "Thirteen patients, aged 27 to 70 years, with definite or classical rheumatoid arthritis were treated with penicillamine for six months." | 7.65 | Penicillamine in rheumatoid arthritis. Connective tissue changes and alterations in serum copper and phase reactants in relation to clinical improvement. ( Andreassen, T; Hansen, TM; Kofod, B; Lorenzen, IB; Manthorpe, R; Oxlund, H, 1976) |
| "The sera of 40 patients with severe progressive rheumatoid arthritis were examined for the presence of soluble immune complexes before penicillamine therapy was started, and again after treatment for a mean period of 14-4 months." | 7.65 | Effect of penicillamine therapy on circulating immune complexes in rheumatoid arthritis. ( Ansell, BM; Barraclough, D; Holborow, EJ; Mohammed, I, 1975) |
| ") developed myasthenia gravis after taking penicillamine." | 7.65 | Myasthenia gravis associated with penicillamine treatment for rheumatoid arthritis. ( Bucknall, RC; Dixon A St, J; Glick, EN; Woodland, J; Zutshi, DW, 1975) |
| "The authors present 5 cases of pemphigus induced by D-penicillamine in a series of 180 cases of rheumatoid arthritis treated with this medication." | 7.65 | [Pemphigus induced by D-penicillamine in rheumatoid arthritis. Study of 5 cases and systematic study of anti-intercellular substance antibodies of the skin in the course of treatment]. ( Benveniste, M; Camus, JP; Crouzet, J; Hewitt, J; Homberg, JC; Lessana, M, 1975) |
| "The technetium index was measured in 22 patients with rheumatoid arthritis, before and after 6 months' treatment either with penicillamine or with anti-inflammatory drugs." | 7.65 | Objective measurement of rheumatoid arthritis using technetium index. ( Balme, HW; Huskisson, EC; Scott, J, 1976) |
| "Bucillamine was at least as effective ad D-penicillamine in terms of improvement in the swollen joint count, tenderness score, morning stiffness, modified health assessment questionnaire, and Westergren erythrocyte sedimentation rate (ESR), and more effective in terms of improvement in the tender joint count, grip strength, C-reactive protein (CRP), and rheumatoid factor (RF) titer." | 6.68 | A comparison between bucillamine and D-penicillamine in the treatment of rheumatoid arthritis. ( Kim, HA; Song, YW, 1997) |
| "To determine whether intermittent rather than daily administration of D-penicillamine (D-Pen) would effectively reduce the incidence of adverse effects without significantly diminishing the clinical benefits." | 6.67 | Intermittent treatment with D-penicillamine is effective in lower doses and with fewer adverse effects in patients with rheumatoid arthritis. ( Akahoshi, T; Hakoda, M; Kamatani, N; Kashiwazaki, S; Taniguchi, A, 1994) |
| "Nausea was the major side effect in the sulphasalazine treated group." | 6.65 | Comparison between penicillamine and sulphasalazine in rheumatoid arthritis: Leeds-Birmingham trial. ( Grindulis, KA; Hubball, S; McConkey, B; Neumann, VC; Wright, V, 1983) |
| "Captopril was therefore considered a potential slow-acting drug for treating rheumatoid arthritis." | 6.65 | Captopril: a new treatment for rheumatoid arthritis? ( Bird, HA; Dixon, JS; Martin, MF; McKenna, F; Surrall, KE; Wright, V, 1984) |
| "Osteoporosis is a common and important feature of rheumatoid disease which can be further influenced by the treatment administered." | 6.65 | Osteoporosis in the rheumatoid hand--the effects of treatment with D-penicillamine and oral gold salts. ( Schorn, D, 1983) |
| " The main task has been seen to be the exploration of various dosage schedules in the hope of finding an effective dose which does not produce a high incidence of adverse effect." | 6.65 | Penicillamine in rheumatoid arthritis. ( Hill, AG; Hill, HF, 1979) |
| "Rheumatoid arthritis is the commonest connective tissue disease associated with bronchiolitis obliterans, a clinico-pathologic entity of bronchiolar inflammation and fibrosis reflecting injury to the small airways, and presenting with symptoms and signs of small airways obstruction." | 6.38 | Bronchiolitis obliterans and rheumatoid arthritis. Report of a case in a Chinese patient on d-penicillamine and review of the literature. ( Wong, R; Yam, LY, 1993) |
| "Rheumatoid arthritis is a severe disease and it is difficult to prevent the progression of disease." | 6.38 | [Gold compounds and D-penicillamine for therapy of rheumatoid arthritis]. ( Inoue, T; Miyamoto, S, 1992) |
| "We performed 2 metaanalyses of placebo-controlled and comparative clinical trials to examine the relative efficacy and toxicity of methotrexate (MTX), injectable gold, D-penicillamine (DP), sulfasalazine (SSZ), auranofin (AUR), and antimalarial drugs, the second-line drugs most commonly used to treat rheumatoid arthritis (RA)." | 6.16 | The comparative efficacy and toxicity of second-line drugs in rheumatoid arthritis. Results of two metaanalyses. ( Anderson, JJ; Felson, DT; Meenan, RF, 1990) |
| "Many clinicians believe that slow-acting therapeutic agents, such as fold, penicillamine, the antimalarials, and cytotoxic drugs, can retard joint destruction in rheumatoid arthritis." | 6.15 | Does drug therapy slow radiographic deterioration in rheumatoid arthritis? ( Dawson, N; Iannuzzi, L; Kushner, I; Zein, N, 1983) |
| " There is no evidence that the dosage of drugs metabolized by the CYP3A4 isoenzyme needs to be adjusted for disease activity in RA." | 5.30 | Urinary 6 beta-hydroxycortisol excretion in rheumatoid arthritis. ( Beyeler, C; Bird, HA; Frey, BM, 1997) |
| " Our findings explain a number of the toxic phenomena associated with D-penicillamine administration in RA." | 5.27 | D-Penicillamine induced toxicity in rheumatoid arthritis: the role of sulphoxidation status and HLA-DR3. ( Emery, P; Huston, G; Idle, JR; Mitchell, SC; Panayi, GS; Shah, RR; Smith, RL; Waring, RH; Welsh, KI, 1984) |
| "Active rheumatoid arthritis is associated with increased numbers of plaque forming cells in the peripheral blood, changes in the numbers of these cells providing an index of disease activity." | 5.27 | The influence of D-penicillamine therapy on numbers of circulating immunoglobulin secreting cells in rheumatoid arthritis. ( Corke, CF; Gul, V; Holborow, EJ; Huskisson, EC, 1984) |
| "Levamisole has been shown to be an effective, penicillamine-like drug." | 5.26 | Treatment of rheumatoid arthritis with levamisole. ( Huskisson, EC, 1980) |
| "Levamisole is a welcome addition to the list of penicillamine-like drugs." | 5.26 | The place of levamisole in the armamentarium for rheumatoid arthritis. ( Huskisson, EC, 1978) |
| " Its indications in the therapy of RA were defined, and current principles of dosage were presented." | 5.26 | Penicillamine in rheumatoid arthritis: clinical pharmacology and biochemical properties. ( Jaffe, IA, 1979) |
| "A retrospective study of penicillamine toxicity in 156 patients yielded a high incidence of toxic reaction (62%), necessitating discontinuation of the drug therapy in 36% of the patients." | 5.26 | Toxicity of penicillamine. A serious limitation to therapy in rheumatoid arthritis. ( Bernhard, GC; Goldman, AL; Halverson, PB; Kozin, F, 1978) |
| "To optimize treatment for rheumatoid arthritis (RA) and to define indications for D-penicillamine and methotrexate therapies on an individual basis by taking into account the levels of rheumatoid factor (RF) isotopes circulating in blood." | 5.09 | [Efficacy of D-penicillamine and methotrexate in the treatment of rheumatoid arthritis in relation to levels of circulating rheumatoid factors of different classes]. ( Derevianko, LI; Sivordova, LE; Zavodovskiĭ, BV; Zborovskaia, IA; Zborovskiĭ, AB, 1999) |
| "A randomly controlled study comprising 100 patients with rheumatoid arthritis (49 control CG; 51 experimental EG) requiring D-penicillamine (DPA)." | 5.09 | Effect of patient education on adherence to drug treatment for rheumatoid arthritis: a randomised controlled trial. ( Bird, H; Hill, J; Johnson, S, 2001) |
| "The aim of our study was to determine the prevalence of thyroid dysfunction and autoimmune abnormalities in rheumatoid arthritis (RA) and to further investigate the possible association between D-penicillamine and autoimmune thyroiditis." | 5.08 | Thyroid function and immune profile in rheumatoid arthritis. A controlled study. ( Andonopoulos, AP; Christofidou, M; Makri, M; Markou, C; Siambi, V; Vagenakis, AG, 1996) |
| "To compare the efficacy of hydroxychloroquine, penicillamine, sodium aurothiomalate and auranofin in the treatment of active rheumatoid arthritis over a period of 5 yr." | 5.08 | A long-term five-year randomized controlled trial of hydroxychloroquine, sodium aurothiomalate, auranofin and penicillamine in the treatment of patients with rheumatoid arthritis. ( Camilleri, JP; Coles, EC; Jessop, JD; Lewis, PA; O'Sullivan, MM; Plant, MJ; Williams, LA, 1998) |
| "We studied the effects of D-penicillamine (DP) on the clinical response, immunoinflammatory parameters and the lymphocyte subsets in 46 patients with rheumatoid arthritis (RA)." | 5.07 | Effect of D-penicillamine on lymphocyte subsets: correlation with clinical response in rheumatoid arthritis. ( Beri, D; Khare, SD; Kumar, A; Malaviya, AN; Malaviya, R; Mehra, NK; Shandilya, R; Sharma, M; Singh, RR; Taneja, V, 1994) |
| "Thiopronin is a second line drug for rheumatoid arthritis with proven efficacy in controlled trials versus a placebo, D-penicillamine, or gold salts." | 5.07 | [A comparative controlled trial of 2 administration modalities of tiopronin in rheumatoid arthritis]. ( Brin, S; Combe, B; Delecoeuillerie, G; Paolozzi, L; Sany, J, 1993) |
| "The toxicity profiles of 7 disease modifying antirheumatic drugs (DMARD) (hydroxychloroquine, intramuscular (im) gold, D-penicillamine, oral gold, methotrexate (MTX), azathioprine and cyclophosphamide) were evaluated in 2,479 patients with rheumatoid arthritis consecutively enrolled at 5 centers in the Arthritis, Rheumatism and Aging Medical Information System (ARAMIS) program." | 5.07 | Toxicity profiles of disease modifying antirheumatic drugs in rheumatoid arthritis. ( Bloch, DA; Fries, JF; Singh, G; Spitz, P; Williams, CA; Zatarain, E, 1991) |
| "Analysis is made of the results of the treatment with parenteral (crysanol and myochrysine) and oral (ridaura) gold drugs as well as with small doses of D-penicillamine (DP) of patients suffering from rheumatoid arthritis with the signs of nephropathy." | 5.07 | [A comparative evaluation of parenteral and oral preparations of gold and D-penicillamine in the treatment of rheumatoid nephropathy]. ( Chichasova, NV; Kanevskaia, MZ; Krel', AA; Krel', OV; Slobodina, GA; Varshavskiĭ, VA, 1991) |
| "Ninety-two patients with active rheumatoid arthritis (RA) were entered in a randomized double blind study of 24 weeks comparing cyclosporine (initial daily dose 5 mg/kg) with D-penicillamine (initial daily dose 250 mg)." | 5.07 | Comparison of cyclosporine and D-penicillamine for rheumatoid arthritis: a randomized, double blind, multicenter study. ( Boers, M; Cats, A; Dijkmans, BA; Meijers, KA; Montnor-Beckers, ZL; Moolenburgh, JD; Thè, HS; van Rijthoven, AW, 1991) |
| "Sixteen patients who had shown a good clinical response to cyclosporine therapy during a randomized 6-month double blind study comparing cyclosporine with D-penicillamine in active rheumatoid arthritis, had an opportunity to participate in an open study with cyclosporine." | 5.07 | Longterm cyclosporine therapy in rheumatoid arthritis. ( Boers, M; Cats, A; Dijkmans, BA; Goei Thè, HS; van Rijthoven, AW, 1991) |
| "An attempt was made to audit the clinical usefulness of sulphasalazine and penicillamine in patients with rheumatoid arthritis (RA) managed in a routine out-patient setting with assistance from general practitioners and to ascertain whether clinically significant differences can be shown between these two 'second-line' agents." | 5.06 | Degree and extent of response to sulphasalazine or penicillamine therapy for rheumatoid arthritis: results from a routine clinical environment over a two-year period. ( Capell, HA; Hunter, JA; Madhok, R; Marabani, M; Torley, H, 1990) |
| "To assess whether monthly treatment with intravenous methylprednisolone enhances or accelerates the effect of disease modifying drugs in patients with rheumatoid arthritis." | 5.06 | Double blind placebo controlled trial of pulse treatment with methylprednisolone combined with disease modifying drugs in rheumatoid arthritis. ( Elling, H; Haar, D; Hansen, TM; Ingeman-Nielsen, MW; Kreutzfeldt, M; Kryger, P; Olsson, AT; Pedersen, C; Rahbek, A; Tvede, N, 1990) |
| "Forty patients with active rheumatoid arthritis were included in this monocentre double-blind study comparing the therapeutic efficacy and safety of the immunomodulator OM-8980 with that of D-penicillamine." | 5.06 | OM-8980 and D-penicillamine in the treatment of rheumatoid arthritis. A 12-month double-blind randomized study. ( Dequeker, J; Sileghem, A; Verstraeten, A, 1990) |
| "Fifty-four patients with rheumatoid arthritis were randomized to either sulphasalazine or D-penicillamine in order to compare the short- and long-term efficacy of these two agents in the treatment of rheumatoid arthritis." | 5.06 | Sulphasalazine versus penicillamine in the treatment of rheumatoid arthritis. ( Breidahl, PD; Carroll, GJ; Tinsley, LM; Will, RK, 1989) |
| "The pharmacokinetic effect of the combined treatment of penicillamine with indomethacin and chloroquine was investigated in patients with rheumatoid arthritis." | 5.06 | Pharmacokinetic interactions of penicillamine in rheumatoid arthritis. ( Lindström, B; Seideman, P, 1989) |
| "Seventy-three patients with early, active rheumatoid arthritis (RA) were randomly allocated either to a group that received penicillamine or to a control group from which penicillamine was barred, any other second-line drug being permitted." | 5.06 | A prospective five-year comparison of treatment which included penicillamine with that excluding penicillamine in early rheumatoid arthritis. The Multicentre Trial Group. ( , 1986) |
| "Twenty-six out-patients with active rheumatoid arthritis (RA) were randomly allocated to treatment with sulphasalazine (SASP) or D-penicillamine (DPA)." | 5.06 | Effects of sulphasalazine on faecal flora in patients with rheumatoid arthritis: a comparison with penicillamine. ( Cooke, EM; Neumann, VC; Shinebaum, R; Wright, V, 1987) |
| " An open trial of SA 96 treatment (300 mg/day after meals for 16 weeks) was carried out in 11 patients with definite or classical rheumatoid arthritis and with therapeutic failure of previous gold salts and/or D-penicillamine therapy." | 5.06 | SA 96 (N-(2-mercapto-2-methylpropanoyl)-L-cysteine) in rheumatoid arthritis. ( Ishikawa, K; Sakaguchi, M, 1986) |
| "After a controlled, double blind multicenter trial of D-penicillamine in the treatment of rheumatoid arthritis, 148 patients were followed for an additional year in an open label trial." | 5.06 | Toxicity of longterm low dose D-penicillamine therapy in rheumatoid arthritis. Cooperative Systematic Studies of Rheumatic Disease Group. ( , 1987) |
| "In a double blind trial of 36 patients with rheumatoid arthritis a new scintimetric method was applied to three comparable patient groups before and after eight months' treatment with levamisole, penicillamine, or azathioprine." | 5.06 | Scintimetric assessment of synovitis activity during treatment with disease modifying antirheumatic drugs. ( Bentzon, MW; Halberg, P; Halskov, O; Olsen, N, 1988) |
| "Forty patients with definite or classical active rheumatoid arthritis were stratified by the minimization procedure to auranofin (6 mg/day) or penicillamine (go slow and low regime)." | 5.06 | Auranofin versus penicillamine in rheumatoid arthritis. One-year results from a prospective clinical investigation. ( Hørbov, S; Manthorpe, R; Sylvest, J; Vinterberg, H, 1986) |
| "Ninety patients were entered into a randomized, controlled, double-blind trial lasting 12 months to compare auranofin (6 mg/d), and D-penicillamine (250 mg/d for 4 weeks, 500 mg/d for 4 weeks, then 750 mg/d thereafter) in the treatment of rheumatoid arthritis." | 5.06 | Auranofin or D-penicillamine in the treatment of rheumatoid arthritis. ( Hochberg, MC, 1986) |
| "Thirty patients with rheumatoid arthritis were allocated to either methylprednisolone pulse therapy or placebo at the beginning of treatment with either gold salts, penicillamine, or azathioprine." | 5.06 | Combination of methylprednisolone pulse therapy and remission inducing drugs in rheumatoid arthritis. ( Dickmeiss, E; Hansen, TM; Ingeman-Nielsen, M; Ingemann Hansen, T; Jans, H; Lorenzen, I, 1987) |
| "Seventy-two patients with relatively early but progressive rheumatoid arthritis were treated with chloroquine sulphate, D-penicillamine or a combination of both drugs over 1 year." | 5.06 | Combined D-penicillamine and chloroquine treatment of rheumatoid arthritis--a comparative study. ( Armstrong, RD; Crisp, AJ; Emery, P; Gibson, T; Panayi, GS, 1987) |
| "The induction of antinuclear antibodies (ANA) by D-penicillamine (DP) was studied in 148 patients with rheumatoid arthritis (RA) who had completed at least 30 weeks in a double blind trial which compared DP at doses 500 mg and 125 mg daily to placebo." | 5.06 | Lack of induction of antinuclear antibodies by D-penicillamine in rheumatoid arthritis: a controlled study. ( Rothfield, NF; Weinstein, A, 1986) |
| "Seventy two patients with classical or definite rheumatoid arthritis (RA) were randomly allocated to receive gold or D-penicillamine therapy (DPA) in a prospective study designed to evaluate whether it is possible to predict which patients will show radiological progression despite therapy." | 5.06 | Prediction of progressive joint damage in patients with rheumatoid arthritis receiving gold or D-penicillamine therapy. ( Collins, M; Dawes, PT; Fowler, PD; Jackson, R; Scott, DL; Shadforth, MF; Stone, R, 1986) |
| "One hundred patients with active rheumatoid arthritis, uncontrolled by symptom relieving agents, were allocated randomly to intramuscular gold or oral penicillamine therapy." | 5.06 | General practitioner assistance with gold and penicillamine therapy of rheumatoid arthritis--a four year prospective study. ( Capell, HA; Hunter, JA; Madhok, R; Pullar, T, 1987) |
| "Two hundred twenty-five patients with active severe rheumatoid arthritis were admitted to a multiclinic, controlled, double-blind trial comparing the use of 500 mg D-penicillamine per day, 125 mg D-penicillamine per day, and placebo." | 5.05 | Low-dose D-penicillamine therapy in rheumatoid arthritis. A controlled, double-blind clinical trial. ( Cathcart, ES; Egger, MJ; Furst, DE; Grandone, JT; Guttadauria, M; Halla, JT; Kaplan, SB; Plotz, PH; Reading, JC; Samuelson, CO; Sullivan, JM; Ward, JR; Watson, MA; Weinstein, A; Williams, HJ, 1983) |
| "Chloroquine and hydroxychloroquine effectively suppress rheumatoid arthritis with a superior benefit to risk ratio." | 5.05 | Antimalarial drugs for rheumatoid arthritis. ( Mackenzie, AH, 1983) |
| "A 2-year, controlled, double-blind trial of D-penicillamine and hydroxychloroquine either alone or in combination was conducted on patients with progressive rheumatoid arthritis." | 5.05 | Controlled trial of hydroxychloroquine and D-penicillamine singly and in combination in the treatment of rheumatoid arthritis. ( Bunch, TW; O'Duffy, JD; O'Fallon, WM; Tompkins, RB, 1984) |
| "Thirty-eight patients with rheumatoid arthritis in remission on penicillamine were entered into a prospective, randomised, placebo controlled study to determine the effects of gradual penicillamine withdrawal, to find a serological marker capable of predicting relapse, and to assess the effects of reintroduction of penicillamine." | 5.05 | D-penicillamine withdrawal in rheumatoid arthritis. ( Ahern, MJ; Case, K; Hall, ND; Maddison, PJ, 1984) |
| "The oral gold salt auranofin, 6 mg per day, was compared with oral d-penicillamine, 500 mg per day, in a single-blind trial in 40 patients suffering with definite or classic rheumatoid arthritis." | 5.05 | A 12-month comparative trial of auranofin and D-penicillamine in rheumatoid arthritis. ( Bateman, JR; Delamere, JP; Felix-Davies, DD; Stewart, AM; Wilkinson, BR, 1983) |
| "Forty-six patients with classical or definite rheumatoid arthritis participated in a prospective clinical trial comparing auranofin 6 mg/day (26 patients) with D-penicillamine 500 mg/day (20 patients) during one year." | 5.05 | Auranofin and D-penicillamine: a one year comparative study of safety and efficacy in patients with rheumatoid arthritis followed by a two year open assessment of auranofin. ( Franchimont, P; Hauwaert, C; Vanschoubroek, K, 1984) |
| "Levamisole (150 mg once weekly) was compared with penicillamine (250 mg daily) in a single blind independent observer study in 28 patients with rheumatoid arthritis over twelve months." | 5.05 | A comparison of low dose levamisole and penicillamine in rheumatoid arthritis. ( Ansell, BM; Bernstein, RM; Clemens, LE; Hall, MA; McCauley, D, 1983) |
| "Results and side effects were compared in 100 patients with rheumatoid arthritis treated with 600 mg penicillamine daily and 100 patients given 300 mg daily." | 5.05 | Low-dose penicillamine treatment of RA. Comparison of 600 mg and 300 mg regimens. ( Mäkisara, P; Nissilä, M; Nuotio, P; von Essen, R, 1982) |
| "In a prospective study 88 patients, with rheumatoid arthritis who had stopped taking gold, penicillamine, or levamisole were randomly allocated to one of the alternative drugs and followed up for a minimum of one year." | 5.05 | Does the order of second-line treatment in rheumatoid arthritis matter? ( Capell, HA; Hunter, JA; Murdoch, RM; Steven, MM, 1982) |
| "Twelve patients with rheumatoid arthritis who had failed to respond to or developed side effects preventing further use of penicillamine were given 5-thiopyridoxine (5-TP)." | 5.05 | 5-Thiopyridoxine in rheumatoid arthritis: clinical and experimental studies. ( Dieppe, PA; Huskisson, EC; Jaffe, IA; Scott, J, 1980) |
| "The medical records of our first 200 consecutive rheumatoid arthritis patients treated with penicillamine were analyzed retrospectively." | 5.05 | Clinical trial of penicillamine in rheumatoid arthritis. ( Bergen, W; Phillips, VK; Rothermich, NO; Thomas, MH, 1981) |
| "In a controlled study involving 36 patients, thymopoietin was shown to be more effective than levamisole and as effective as penicillamine in improving the clinical status of patients with rheumatoid arthritis." | 5.05 | Thymopoietin in rheumatoid arthritis. ( Doyle, DV; Huskisson, EC; Scott, J; Thrower, PA, 1982) |
| "Pulsed methylprednisolone (PMP) has been shown to produce clinical improvement and reduction in the ESR and acute phase protein concentrations in patients with active rheumatoid arthritis and has been advocated for use either as an alternative to slow-acting antirheumatoid drugs (SAARDs) or in conjunction with SAARDs to accelerate the response to treatment." | 5.05 | Combination therapy with pulsed methylprednisolone in rheumatoid arthritis. ( Bird, H; Dixon, J; Hopkins, R; Neumann, V; Watkins, A; Wright, V, 1985) |
| "The effect of synthetic adrenocorticotrophic hormone (Synacthen), in conjunction with hydroxychloroquine, aurothioglucose, or penicillamine, was evaluated retrospectively in 21 patients with rheumatoid arthritis (RA)." | 5.05 | Short course of synacthen therapy as an adjunct in the management of rheumatoid arthritis. ( Ben-Chetrit, E; Ehrenfeld, M; Eliakim, M; Naparstek, Y, 1985) |
| "The authors studied and compared the action of chlorbutin, azathioprin, of large and mean doses of D-penicillamine and levamisole with that of nonsteroidal antiinflammatory drugs (NAID) on rheumatoid arthritis systemic manifestations in 186 patients treated with these drugs for more than 3 months." | 5.05 | [Chlorbutin, azathioprine, D-penicillamine and levamisole (decaris) in the treatment of patients with rheumatoid arthritis. IV. Comparative evaluation of their effects on systemic (extra-articular) manifestations of the disease]. ( Chichasova, NV; Kanevskaia, MZ; Khamishon, LZ; Krel', AA; Nemchenov, EN, 1985) |
| "Forty-six patients with rheumatoid arthritis, 22 receiving D-penicillamine and 2j alclofenac, took part in a 6-month single-bind external observer trial to compare the efficacy and toxicity of these drugs in the treatment of severe rheumatoid arthritis." | 5.04 | Alclofenac and D-penicillamine. Comparative trial in rheumatoid arthritis. ( Berry, H; Evans, SJ; Fernandes, L; Ford-Hutchinson, AW; Hamilton, EB, 1978) |
| "In a controlled study involving thirty-four patients levamisole was shown to be as effective as D-penicillamine and more effective than placebo in the treatment of rheumatoid arthritis." | 5.04 | Immunostimulant therapy with levamisole for rheumatoid arthritis. ( Balme, HW; Dieppe, PA; Huskisson, EC; Scott, J; Trapnell, J; Willoughby, DA, 1976) |
| "In a series of 100 adult patients with definite rheumatoid arthritis of at most 3 years' duration and with no previous penicillamine, gold or systemic corticosteroid treatment, 50 patients were treated with D-penicillamine and 50 with gold for one yar." | 5.04 | Comparison of penicillamine and gold treatment in early rheumatoid arthritis. ( Anttila, P; Kajander, A; Mäkisara, GL; Mäkisara, P; Martio, J; Nissilä, M; von Essen, R, 1978) |
| "Twenty-six patients with rheumatoid arthritis were treated with sodium aurothiomalate (16 patients) and penicillamine (10 patients) for 9 months." | 5.04 | Serum sulfhydryl levels in rheumatoid patients treated with gold thiomalate and penicillamine. ( Haataja, M; Nissilä, M; Ruutsalo, HM, 1978) |
| "Alclofenac and D-penicillamine were compared under controlled, double-blind conditions in the treatment of 35 patients with active rheumatoid arthritis over a period of 26 weeks." | 5.04 | The influence of alclofenac treatment on acute-phase proteins, plasma tryptophan, and erythrocyte sedimentation rate in patients with rheumatoid arthritis. ( Aylward, M; Holly, F; Maddock, J; Rees, P, 1975) |
| "Reports of 28 authors with a total of nearly 1,000 enrolled patients have been reviewed regarding changes in clinical manifestations of disease in rheumatoid arthritis during short term and long term administration of levamisole." | 5.04 | International symposium on levamisole in rheumatoid arthritis. A review of short and longterm effects on articular manifestations. ( Basch, CM; Engleman, EP; Spitler, LE, 1978) |
| "A statistically significant decrease of erythrocyte sedimentation rate (ESR) is seen in levamisole-treated rheumatoid arthritis (RA) patients." | 5.04 | A review of the effects of levamisole on erythrocyte sedimentation rate, acute phase proteins, and anemia. ( Sany, J, 1978) |
| "The use of penicillamine in the treatment of rheumatoid arthritis and scheroderma is reviewed." | 5.04 | The use of penicillamine in the treatment of rheumatoid arthritis and scleroderma. ( Baum, J, 1979) |
| "Doses of 600 mg and 1200 mg of D(-)penicillamine daily were superior to a standard regimen of therapy in rheumatoid arthritis." | 5.04 | Synthetic D(-)penicillamine in rheumatoid arthritis. Double-blind controlled study of a high and low dosage regimen. ( Davies, J; Dixon, AJ; Dormandy, TL; Hamilton, EB; Holt, PJ; Mason, RM; Thompson, M; Weber, JC; Zutshi, DW, 1975) |
| "Sixty-five patients, 33 receiving azathioprine and 32 receiving penicillamine, took part in a one-year, single-blind external-observer trial designed to compare the efficacy and toxicity of these two drugs in the treatment of rheumatoid arthritis." | 5.04 | Azathioprine and penicillamine in treatment of rheumatoid arthritis: a controlled trial. ( Barnes, CG; Berger, LA; Berry, H; Durance, RA; Evans, S; Liyanage, SP, 1976) |
| "In a controlled trial including 80 patients suffering from different stages of rheumatoid arthritis it was demonstrated that D-penicillamine therapy favourably influences the clinical course of the disease as compared to a control group treated with antirheumatic drugs." | 5.04 | [Long term treatment of rheumatoid arthritis. Experiences with D-penicillamine in comparison with gold and immunosuppressive drugs (author's transl)]. ( Gutmann, W; Scheiffarth, F; Warnatz, H, 1975) |
| "To estimate the short-term effects of D-penicillamine for the treatment of rheumatoid arthritis (RA)." | 4.80 | Penicillamine for rheumatoid arthritis. ( Belseck, E; Spooner, C; Suarez-Almazor, ME, 2000) |
| "To estimate the short-term effects of D-penicillamine for the treatment of rheumatoid arthritis (RA)." | 4.80 | Penicillamine for treating rheumatoid arthritis. ( Belseck, E; Spooner, C; Suarez-Almazor, ME, 2000) |
| " Large placebo-controlled studies of both sulfasalazine and hydroxychloroquine have been reported and have demonstrated the efficacy of these agents in the treatment of early rheumatoid arthritis." | 4.79 | Disease-modifying antirheumatic drugs, including methotrexate, gold, antimalarials, and D-penicillamine. ( Brooks, P; Conaghan, PG, 1995) |
| " In particular, we describe renal syndromes associated with non-steroidal antiinflammatory drugs, remission-inducing agents (gold and penicillamine) and cytotoxic drugs, secondary amyloidosis, systemic rheumatoid vasculitis, glomerular and tubulo-interstitial nephritis not related to drug therapy." | 4.79 | [Renal damage in rheumatoid arthritis]. ( Bruno, M; Cosseddu, D; Linari, F; Manganaro, M; Pellerito, R; Ravarino, N; Torchio, B; Urbano, D, 1994) |
| "To perform a cost effectiveness analysis of cyclosporine (CyA) in the treatment of rheumatoid arthritis (RA)." | 4.79 | A cost effectiveness analysis of cyclosporine in rheumatoid arthritis. ( Anis, AH; Stewart, DG; Tugwell, PX; Wells, GA, 1996) |
| "Treatment of rheumatoid arthritis (RA) with D-penicillamine (DP) is associated with development of dermatopolymyositis (DPM) in 0." | 4.78 | [Dermatopolymyositis induced by D-penicillamine in rheumatoid polyarthritis. Apropos of 1 case with review of the literature]. ( Bahloul, Z; Gouiaa, R; Hachicha, J; Jarraya, A; Kolsi, R, 1992) |
| "Between 1979 and 1990 we have seen 8 patients (7 females) with rheumatoid arthritis (RA) who developed a neuro-muscular involvement while on D-penicillamine (D." | 4.78 | [Neuromuscular complications of D-penicillamine in rheumatoid arthritis]. ( Bouchet, F; Bussière, JL; Dubost, JJ; Kemeny, JL; Lhopitaux, R; Sauvezie, B; Soubrier, M, 1992) |
| "We have encountered a 53 year-old female with myasthenia gravis (MG) possibly induced by the treatment with D-penicillamine (D-pc)." | 4.78 | [D-penicillamine induced myasthenia gravis in a patient with rheumatoid arthritis]. ( Hosoya, T; Kuriyama, S; Sakai, O, 1991) |
| "Three aspects of the action of oxygenated free radicals were studied in 10 controls and 20 patients with rheumatoid arthritis, 11 not treated and 9 treated with D-penicillamine." | 4.78 | [Anti-radical enzymes, oxygenated free radicals and lipoperoxydation in rheumatoid polyarthritis. Effects of treatment with D-penicillamine]. ( Abella, A; Baret, A; Bauer, D; Bisson, M; Chalas, J; Clerc, D; Francoual, J; Leluc, R; Lindenbaum, A; Menkès, CJ, 1990) |
| "A patient with severe rheumatoid arthritis received d-penicillamine treatment for 16 months." | 4.78 | D-penicillamine induced pemphigus treated with methylprednisolone pulse therapy. ( De Clerck, LS; Francx, L; Stevens, WJ; Wouters, EA, 1990) |
| "Pemphigus erythematosus occurred in a patient with rheumatoid arthritis who was treated with D-penicillamine." | 4.78 | Penicillamine-induced pemphigus erythematosus. ( De Coninck, AL; De Raeve, LE; Roseeuw, DI; Willemsen, MJ, 1990) |
| "In the present study, the side effects of d-Penicillamine therapy in 54 patients with rheumatoid arthritis are analyzed." | 4.77 | [Side effects of d-penicillamine in the treatment of rheumatoid arthritis]. ( Bianchini, D; Cataldo, R; Damiani, D; Florean, M; Mazzanti, G; Mesesnel, E; Paladini, G, 1986) |
| "The present paper reviews the different therapeutic uses of D-penicillamine and outlines the dosage regimen of D-penicillamine for treatment of rheumatoid arthritis." | 4.77 | [D-penicillamine--a current review of areas of use and dosage guidelines]. ( Sörensen, H, 1988) |
| "Auranofin, the only approved oral gold complex of value in suppressing rheumatoid arthritis, differs from injectable gold compounds molecularly and pharmacologically." | 4.77 | Pharmacology of auranofin: overview and update. ( Gottlieb, NL, 1986) |
| "Although several agents (for example, intramuscularly administered gold, auranofin, D-penicillamine, hydroxychloroquine, and methotrexate) are of clinical benefit in the management of rheumatoid arthritis (RA), their effect on the long-term outcome of the disease is controversial." | 4.77 | Rheumatoid arthritis: can the long-term outcome be altered? ( Gabriel, SE; Luthra, HS, 1988) |
| "After reviewing the history of the discovery of the action of D-penicillamine in rheumatoid arthritis, the authors define the practical modalities for the management of treatment based on their own experience and on the data from the literature." | 4.77 | [Penicillamine in 1985]. ( Camus, JP; Koeger, AC; Laveant, C; Leca, AP, 1986) |
| "Three cases of penicillamine induced pemphigus are described and compared to 35 previously reported cases with typical direct immunofluorescence." | 4.77 | Penicillamine induced pemphigus. ( Ho, VC; McLeod, WA; Ongley, RA; Stein, HB, 1985) |
| "A review of the literature on the longterm use of methotrexate in patients with rheumatoid arthritis (RA) showed that many questions on protocol remain unanswered." | 4.77 | Longterm methotrexate therapy in rheumatoid arthritis: a review. ( Kremer, JM, 1985) |
| " Conditions often associated with rheumatoid arthritis and also thought to have an immunologic basis, such as Sjögren's syndrome, Felty's syndrome, and rheumatoid vasculitis, and reactions to medications, such as gold and penicillamine, reveal an interesting spectrum of immunogenetic relationships." | 4.76 | Rheumatoid arthritis: relationship with HLA-D. ( Stastny, P, 1983) |
| " Injectable gold compounds and penicillamine are not contraindicated in the elderly, because they are just as efficacious as in younger persons for the treatment of rheumatoid arthritis." | 4.76 | Problems of antiarthritic therapy in the elderly. ( Brooks, PM; Buchanan, WW; Kassam, Y; Kean, WF, 1984) |
| "The use of penicillamine in rheumatoid arthritis (RA) is limited by the incidence of adverse effects, some of which are potentially hazardous." | 4.76 | Penicillamine in rheumatoid arthritis: adverse effects. ( Hill, HF, 1979) |
| "Penicillamine is a chelator that has been used in Wilson's disease, cystinuria, rheumatoid arthritis and heavy metal intoxication." | 4.31 | Penicillamine-induced degenerative dermopathy in a patient with Wilson's disease. ( Chen, M; Chen, Y; Gao, L; Jiang, Y; Qiu, X; Qiu, Y, 2023) |
| "To compare the risk of incident hypertension between initiators of tumor necrosis factor (TNF)-α inhibitors and initiators of nonbiologic disease modifying antirheumatic drugs (hereafter referred to as nonbiologics) in rheumatoid arthritis patients taking methotrexate monotherapy." | 3.83 | Tumor Necrosis Factor-α Inhibitor Use and the Risk of Incident Hypertension in Patients with Rheumatoid Arthritis. ( Danaei, G; Desai, RJ; Kim, SC; Liao, KP; Schneeweiss, S; Solomon, DH, 2016) |
| "Rheumatoid arthritis is characterized by immunologically mediated chronic inflammation of synovial structures." | 3.75 | Remission-inducing therapy in rheumatoid arthritis. ( Lipsky, PE, 1983) |
| "A 63-year-old woman had D-penicillamine-induced pemphigus with a high index value of circulating autoantibodies against desmoglein 1." | 3.72 | D-penicillamine-induced pemphigus successfully treated with combination therapy of mizoribine and prednisolone. ( Hirokawa, H; Izu, K; Sugita, K; Tokura, Y, 2004) |
| "In this study we report our two years experience of methotrexate (MTX) in the management of rheumatoid arthritis (RA) at the Aga Khan University Hospital, Karachi." | 3.70 | Methotrexate in rheumatoid arthritis: a 2 year experience at a university hospital in Pakistan. ( Ali, AA; Beg, JA; Hussain, MA; Iqbal, MP; Mehboobali, N; Rahbar, MH, 1998) |
| "SA96 (generic name, bucillamine) is a disease-modifying anti-rheumatoid arthritis (RA) drug with immunological effects." | 3.70 | Pharmacological effects of SA96 (bucillamine) and its metabolites as immunomodulating drugs--the disulfide structure of SA-96 metabolites plays a critical role in the pharmacological action of the drug. ( Kubo, T; Matsuno, H; Matsuura, K; Muraguchi, A; Nezuka, T; Sugiyama, E; Tsuji, H, 1998) |
| "To investigate whether the therapeutic response of rheumatoid arthritis (RA) patients to D-penicillamine is associated with polymorphisms in genes of the glutathione S-transferase (GST) supergene family." | 3.70 | The therapeutic response to D-penicillamine in rheumatoid arthritis: influence of glutathione S-transferase polymorphisms. ( Alldersea, JE; Dawes, PT; Fryer, AA; Jones, PW; Layton, MA; Mattey, DL; Strange, RC, 1999) |
| "A 67-year old woman who had been taking D-penicillamine for 15 months for rheumatoid arthritis was hospitalized due to the development of a bullous eruption and proximal muscle deficiency." | 3.70 | [D-penicillamine-induced pemphigus, polymyositis and myasthenia]. ( Callens, A; Jan, V; Lorette, G; Machet, L; Machet, MC; Vaillant, L, 1999) |
| "Accelerated nodulosis is a recognized complication of methotrexate (MTX) therapy in rheumatoid arthritis (RA)." | 3.70 | Successful treatment of methotrexate induced nodulosis with D-penicillamine. ( Dash, S; Seibold, JR; Tiku, ML, 1999) |
| "To study the long-term efficacy and safety of methotrexate (MTX), intramuscular gold, azathioprine (AZA), chloroquine (CQ), sulphasalazine (SASP), and D-penicillamine (DPA) in rheumatoid arthritis (RA) patients." | 3.70 | Long-term application of disease modifying antirheumatic drugs (DMARD). A single-center, observational study of 1681 patients with rheumatoid arthritis (RA). ( Keysser, C; Keysser, G; Keysser, M, 1999) |
| "We present here a case of MPO-ANCA positive rapidly progressive glomerulonephritis (RPGN) after 34 months of D-penicillamine (D-PC) therapy for rheumatoid arthritis (RA)." | 3.70 | [MPO-ANCA positive rapidly progressive glomerulonephritis in a patient with rheumatoid arthritis during treatment with D-penicillamine]. ( Akama, H; Hara, M; Kamatani, N; Nanke, Y; Terai, C, 1999) |
| "To investigate the mechanism of autoimmune phenomena, occasionally seen in patients with rheumatoid arthritis treated with bucillamine (BUC) and D-penicillamine (D-Pen), by evaluating their effects on apoptosis of T cells induced by T cell receptor activation or dexamethasone." | 3.70 | In vitro and in vivo inhibition of activation induced T cell apoptosis by bucillamine. ( Hirata, D; Iwamoto, M; Kamimura, T; Kano, S; Masuyama, JI; Mimori, A; Minota, S; Okazaki, H; Sato, H; Yoshio, T, 2000) |
| "We present 3 cases of anti-myeloperoxidase, anti-neutrophil cytoplasmic antibody (MPO-ANCA)-positive rapidly progressive glomerulonephritis developed during the treatment with D-penicillamine (D-PC) for rheumatoid arthritis." | 3.70 | Rapidly progressive glomerulonephritis with D-penicillamine. ( Akama, H; Kamatani, N; Nanke, Y; Terai, C, 2000) |
| "Five patients out of 71 with rheumatoid arthritis (RA), who received D-penicillamine, developed myasthenia gravis (MG) within a two-year period." | 3.69 | D-penicillamine induced myasthenia gravis in rheumatoid arthritis: an unpredictable common occurrence? ( Andonopoulos, AP; Papapetropoulos, T; Papasteriades, CA; Terzis, E; Tsibri, E, 1994) |
| "Patients with rheumatoid arthritis (RA) (n = 118) who have used or still use antimalarials (chloroquine or hydroxychloroquine)." | 3.69 | Antimalarial drug induced decrease in creatinine clearance. ( Breedveld, FC; Dijkmans, BA; Goeei The, SG; Landewé, RB; Van Rijthoven, AW; Vergouwen, MS, 1995) |
| "Myasthenia gravis may be observed due to treatment with penicillamine (D-PA)." | 3.69 | Reduced sulphoxidation capacity in D-penicillamine induced myasthenia gravis. ( Ayesh, R; Seideman, P, 1994) |
| "D-penicillamine, a drug used to treat rheumatoid arthritis, Wilson's disease, and cystinuria, can cause myasthenia gravis." | 3.69 | D-penicillamine-induced myasthenia gravis: diagnosis obscured by coexisting chronic obstructive pulmonary disease. ( Adelman, HM; Mahan, CS; Wallach, PM; Winters, PR, 1995) |
| "We describe a 63-year-old female patient with rheumatoid arthritis who developed complete heart block and features of polymyositis within a few weeks of starting treatment with D-penicillamine." | 3.69 | D-penicillamine induced polymyositis causing complete heart block. ( Bell, AL; Wilson, C; Wright, GD, 1994) |
| "D-penicillamine has been used in the treatment of rheumatoid arthritis for years." | 3.69 | [D-penicillamine-induced myasthenia gravis]. ( Frey, RA; Keller, F; Michel, BA, 1994) |
| "A 53-year-old woman with rheumatoid arthritis developed myasthenia gravis after 6 months of therapy with D-penicillamine." | 3.69 | D-penicillamine and gold salt treatments were complicated by myasthenia and pemphigus, respectively, in the same patient with rheumatoid arthritis. ( Agelli, M; Bazzichi, L; Ciompi, ML; Marchetti, G; Puccetti, L, 1995) |
| " During treatment with D-penicillamine the patient developed a transient lupus-like disorder with glomerulonephritis that resolved when D-penicillamine was discontinued." | 3.69 | C1 inhibitor deficiency in a patient with rheumatoid arthritis--increased risk of adverse effects of penicillamine? ( Alm, P; Rydgren, L; Sjöholm, AG; Sturfelt, G; Truedsson, L, 1996) |
| "D-penicillamine, an agent still used in the treatment of rheumatoid arthritis (RA) may produce inflammatory myopathy or myositis." | 3.69 | D-penicillamine-induced myositis in rheumatoid arthritis. ( Chappel, R; Willems, J, 1996) |
| " Both patients (one case of progressive systemic sclerosis and one of rheumatoid arthritis) were currently taking D-penicillamine." | 3.68 | Unilateral ptosis as an initial manifestation of D-penicillamine induced myasthenia gravis. ( Fries, JF; Kornfeld, P; Lee, YS; Raynauld, JP, 1993) |
| "A 57-yr-old lady developed polymyositis whilst taking D-penicillamine for RA." | 3.68 | D-penicillamine and polymyositis: the significance of the anti-Jo-1 antibody. ( Hull, RG; Jenkins, EA; Thomas, AL, 1993) |
| "A 67-year-old woman with rheumatoid arthritis presented rapidly progressive glomerulonephritis (RPGN) after 5 months of D-penicillamine (250 mg/day) treatment." | 3.68 | Penicillamine-induced rapidly progressive glomerulonephritis in a patient with rheumatoid arthritis. ( Alcorta, I; Almirall, J; Botey, A; Revert, L, 1993) |
| "We report the case of an 80-year-old woman who developed pemphigus foliaceus while taking penicillamine for rheumatoid arthritis." | 3.68 | [Pemphigus foliaceus caused by penicillamine]. ( Burg, G; Burger, M; Hartmann, AA; Zentner, A; Zillikens, D, 1993) |
| "A 55-year-old woman with advanced rheumatoid arthritis developed rapidly progressive glomerulonephritis with epithelial crescents and pulmonary hemorrhage following treatment with D-penicillamine." | 3.68 | D-penicillamine therapy associated with rapidly progressive glomerulonephritis. ( Azofra, JA; Fernandez, G; García Díaz, JE; Gonzalez, E; Macarrón, P; Martín de Francisco, J; Sampedro, J, 1992) |
| "We have observed a high incidence of pemphigus foliaceous, in the absence of therapy with penicillamine, within a small population of patients with rheumatoid arthritis." | 3.68 | Rheumatoid arthritis: an association with pemphigus foliaceous. ( Davis, MJ; Dawes, PT; Hollowood, K; Smith, AG; Wilkinson, SM, 1992) |
| "Nine cases of penicillamine induced pemphigus (PIP) in rheumatoid arthritis patients are reported." | 3.68 | HLA system and penicillamine induced pemphigus in nine cases of rheumatoid arthritis. ( Bauer-Vinassac, D; Escande, JP; Menkes, CJ; Muller, JY, 1992) |
| "Spin echo NMR analysis is used to monitor the effect of penicillamine on intact erythrocytes obtained from patients suffering from rheumatoid arthritis during a 12-week period of therapy." | 3.68 | Clinical analysis by 1H spin-echo NMR. 2. Oxidation of intracellular glutathione as a consequence of penicillamine therapy in rheumatoid arthritis. ( Brzeski, M; Marabani, M; Reglinski, J; Smith, WE; Sturrock, RD, 1992) |
| "To determine if a policy of continuing penicillamine therapy in successfully treated patients with rheumatoid arthritis in the presence of persistent proteinuria, was associated or not with resolution of this adverse effect, a computer record of patients receiving penicillamine for rheumatoid arthritis was searched for patients with persistent proteinuria and the case notes of these patients reviewed." | 3.68 | Management of proteinuria secondary to penicillamine therapy in rheumatoid arthritis. ( DeSilva, RN; Eastmond, CJ, 1992) |
| "A female patient with IgM RF seropositive rheumatoid arthritis according to criteria of the American Rheumatism Association was treated for 133 months with Penicillamine and for 17 months also with Sulfasalazine." | 3.68 | [Rheumatoid arthritis developing into systemic lupus erythematosus during long-term treatment with penicillamine and sulfasalazine]. ( Hrncír, Z; Pintérová, E; Rejchrt, S, 1991) |
| "In a study of the costs for drug therapy, 81 patients with rheumatoid arthritis taking parenteral gold, penicillamine or chloroquine were included." | 3.68 | Disease-modifying anti-rheumatic drug therapy. An expensive therapy despite inexpensive drugs. ( Allander, E; Borg, G; Goobar, JE, 1990) |
| "C4 null alleles and HLA-DR antigens were defined in 48 rheumatoid arthritis (RA) subjects who had developed renal or heamatological side effects to gold or penicillamine, as compared to 33 RA subjects who had received the drugs for similar time periods without developing side effects." | 3.68 | Complement C4 null alleles as a marker of gold or D-penicillamine toxicity in the treatment of rheumatoid arthritis. ( Clarkson, RW; Grennan, DM; Sanders, PA, 1992) |
| "Sixty-two consecutive patients, with rheumatoid arthritis (RA) who received D-penicillamine were studied retrospectively to identify predictive risk factors for D-penicillamine toxicity." | 3.68 | D-penicillamine toxicity in Greek patients with rheumatoid arthritis: anti-Ro(SSA) antibodies and cryoglobulinemia are predictive factors. ( Drosos, AA; Moutsopoulos, HM; Skopouli, FN; Vlachoyiannopoulos, PG; Zerva, LV, 1991) |
| "A 40 year old woman with rheumatoid arthritis developed pure red cell aplasia after treatment with D-penicillamine 500 mg/day." | 3.68 | Pure red cell aplasia caused by D-penicillamine treatment of rheumatoid arthritis. ( Kahn, Y; Tishler, M; Yaron, M, 1991) |
| "The distribution of autoantibodies was studied in patients with rheumatoid arthritis (RA) treated by D-penicillamine and who developed myasthenia gravis (MG)." | 3.68 | Autoantibodies in D-penicillamine-induced myasthenia gravis: a comparison with idiopathic myasthenia and rheumatoid arthritis. ( Bach, JF; Bataille, R; D'Anglejan, J; Feuillet-Fieux, MN; Morel, E; Raimond, F; Sany, J; Vernet-der Garabedian, B, 1991) |
| "Recently, the disease activity has been believed to be effectively controlled by remission inducing agents such as gold salt and D-penicillamine in rheumatoid arthritis." | 3.68 | [Frequency and prognostic features of rheumatoid patients with remission-inducing agents--a comparison of different kinds of medication]. ( Kawaguchi, M; Kutsuna, T; Maeda, K; Okamoto, T, 1990) |
| "After considering the cutaneous side effects of D-penicillamine in rheumatoid arthritis management, a few cases of cutaneous adverse reaction observed in 5 (13%) of 38 patients, who received the drugs, are described." | 3.68 | [Cutaneous side effects induced by D-penicillamine in the treatment of rheumatoid arthritis]. ( Baratelli, E; Broggini, M; Cappelli, A; Crespi, E; Filardi, PG; Volontè, S, 1990) |
| "We report a case of a 47-year-old woman with rheumatoid arthritis who developed ocular myasthenia gravis during penicillamine treatment." | 3.68 | Penicillamine-induced ocular myasthenia gravis in rheumatoid arthritis. ( Bienfang, DC; Liu, GT, 1990) |
| "We report a retrospective study of 16 patients with seropositive rheumatoid arthritis who were placed on combination D-penicillamine and methotrexate therapy for a period of 5-86 months." | 3.68 | Combination D-penicillamine and methotrexate therapy: proposal for early and aggressive treatment for rheumatoid arthritis. ( Lee, S; Solomon, G, 1990) |
| "We have studied 23 patients receiving penicillamine for the treatment of rheumatoid arthritis to determine the prevalence of penicillamine-induced elastosis." | 3.68 | Elastic fibre damage induced by low-dose D-penicillamine. ( Burge, SM; Dalziel, KL; Frith, PA; Mowat, A; Ryan, TJ, 1990) |
| " The plasma pharmacokinetics of D-penicillamine (D-pen) and D-penicillamine-albumin disulphide (D-pen-alb) were examined over a dosage interval in six patients with rheumatoid arthritis." | 3.68 | D-penicillamine and D-penicillamine-protein disulphide in plasma and synovial fluid of patients with rheumatoid arthritis. ( Day, RO; Joyce, DA, 1990) |
| "Seven clinical and laboratory indices of disease activity were compared with serum vitamin B12 levels in 32 patients with rheumatoid arthritis treated with penicillamine (16 patients) or sulphasalazine (16 patients) for up to 24 weeks." | 3.67 | Rheumatoid arthritis: is serum vitamin B12 high in active disease? ( Calverley, M; Cox, C; Grindulis, KA, 1984) |
| "The outcome of attempts to continue treatment indefinitely with either gold, penicillamine, sulphasalazine, or dapsone was studied in 240 patients with rheumatoid arthritis (RA)." | 3.67 | Outcome of attempts to treat rheumatoid arthritis with gold, penicillamine, sulphasalazine, or dapsone. ( Grindulis, KA; McConkey, B, 1984) |
| "The long term efficacy and tolerability of sulphasalazine (SASP) in the treatment of 21 patients with active classical or definite rheumatoid arthritis (RA) were examined and compared with the effects of penicillamine in a similarly active group of RA patients." | 3.67 | The long term effects of sulphasalazine in the treatment of rheumatoid arthritis and a comparative study with penicillamine. ( Bacon, PA; Crockson, AP; Farr, M; Tunn, E, 1984) |
| "Optic neuropathy developed in a patient with rheumatoid arthritis who had been receiving D-penicillamine for about 1 year." | 3.67 | Optic neuropathy associated with penicillamine therapy in a patient with rheumatoid arthritis. ( Burde, RM; Klingele, TG, 1984) |
| "Two personal observations of febrile reaction to D-penicillamine in patients with rheumatoid arthritis provide the opportunity for recalling the clinical presentation which is fairly uniform." | 3.67 | [Febrile reaction to D-penicillamine]. ( Blotman, F; Seror, P; Simon, L, 1984) |
| "Eighty four patients with classical rheumatoid arthritis were treated with 300-1 200 mg/day of D-Penicillamine." | 3.67 | [Lupus biology: incidence and development in 84 rheumatoid polyarthritis patients treated with D-penicillamine]. ( Bisson, M; Clerc, D; Massias, P; Sallière, D; Segond, P, 1984) |
| "One hundred sixty-two consecutive patients with rheumatoid arthritis (RA) were studied for possible association between HLA antigens, particularly DR antigens, and disease characteristics and adverse reactions to gold or D-penicillamine treatment." | 3.67 | A systematic survey of HLA-A,B,C and D antigens and drug toxicity in rheumatoid arthritis. ( Dequeker, J; Van Wanghe, P; Verdickt, W, 1984) |
| "Four patients with rheumatoid arthritis developed heavy proteinuria after 5 to 12 months of treatment with D-penicillamine." | 3.67 | Immunopathology of penicillamine-induced glomerular disease. ( Dische, FE; Hamilton, EB; Parsons, V; Swinson, DR, 1984) |
| "As it is known that platelets play an important role in arising and maintaining the inflammation, the authors have studied "in vitro", the effect on platelet aggregation of three drugs (Sodium Aurothiomalate, Auranofin and Penicillamine) used in basic therapy of Rheumatoid Arthritis (RA)." | 3.67 | [Possible mechanism of action of drugs in the basic therapy of rheumatoid arthritis: effect on platelet aggregation]. ( Castagna, ML; Fioravanti, A; Frati, E; Giordano, N; Lalumera, M; Lolatte, V; Marcolongo, R; Morozzi, G, 1984) |
| "The concentration of selenium in serum (S-Se) was studied in 20 patients and glutathione in erythrocytes (E-GSH) in 16 patients with rheumatoid arthritis (RA) at onset and after 3 and 6 months of antirheumatic therapy with aurothiomalate (19 cases) or with D-penicillamine (one case)." | 3.67 | Glutathione and selenium in rheumatoid arthritis. ( Alfthan, G; Hannonen, P; Möttönen, T; Oka, M; Seppälä, O, 1984) |
| "Prospective and retrospective analysis of data obtained on 119 patients with rheumatoid arthritis suggested a relationship between clinical response induced by gold salts or D-penicillamine and decreased in vitro antibody synthesis by peripheral blood mononuclear cells." | 3.67 | Decreased pokeweed mitogen-induced IgM and IgM rheumatoid factor synthesis in rheumatoid arthritis patients treated with gold sodium thiomalate or penicillamine. ( Jasin, HE; Olsen, NJ, 1984) |
| "Zinc in granulocytes, erythrocytes, serum, urine and zinc-dependent enzymes (alkaline phosphatase in serum and granulocytes, carbonic anhydrase in erythrocytes) were measured in patients with rheumatoid arthritis before and during penicillamine therapy for 6 months." | 3.67 | Changes in zinc and zinc-dependent enzymes in rheumatoid patients during penicillamine treatment. ( Jepsen, LV; Pedersen, KH, 1984) |
| "One hundred sixty-eight patients with rheumatoid arthritis treated with chloroquine (n = 87), gold salts (n = 133) and/or penicillamine (n = 77) were investigated for possible associations between HLA antigens and toxic reactions." | 3.67 | HLA antigens and toxicity to gold and penicillamine in rheumatoid arthritis. ( Kolarz, G; Mayr, WR; Mayrhofer, F; Scherak, O; Smolen, JS; Thumb, NJ, 1984) |
| "We studied patients with rheumatoid arthritis who have been treated with aurothioglucose (Au) and subsequently with D-penicillamine (DP), and who developed drug-induced proteinuria, over a 10-year period." | 3.67 | The relationship between aurothioglucose- and D-penicillamine-induced proteinuria. ( Rasker, JJ; Reekers, P; Speerstra, F; van de Putte, LB; Vandenbroucke, JP, 1984) |
| "The bone mineral content (BMC) in both forearms (highly correlated to total body calcium) was measured by photon absorptiometry in a representative sample of rheumatoid arthritis outpatients comprising 129 patients treated with either gold salts (n = 29), penicillamine (n = 61), prednisone (n = 24), or other anti-RA drugs (n = 15)." | 3.67 | Prevalence of decreased bone mass in rheumatoid arthritis. Relation to anti-inflammatory treatment. ( Als, OS; Christiansen, C; Hellesen, C, 1984) |
| "Natural killer (NK) activity against K 562 target cells was studied in 60 patients with definite or classic rheumatoid arthritis (RA), grouped by medication into 1) Controls not in remission-inducing therapy, 2) Patients treated with penicillamine, and 3) Patients treated with azathioprine." | 3.67 | Azathioprine as single drug in the treatment of rheumatoid arthritis induces complete suppression of natural killer cell activity. ( Beyer, JM; Helin, P; Hørslev-Petersen, K; Klarlund, K; Pedersen, BK; Pedersen, BN; Rasmussen, A, 1984) |
| "After administration of D-penicillamine to patients with rheumatoid arthritis, measurements of serum level and urinary excretion showed half-life times of 1." | 3.67 | D-penicillamine in patients with rheumatoid arthritis. Serum levels, pharmacokinetic aspects, and correlation with clinical course and side effects. ( Ament, HJ; Henrichs, AM; Muijsers, AO; van de Stadt, RJ; van der Korst, JK, 1984) |
| "The prevalence of eosinophilia in 66 patients with rheumatoid arthritis receiving D-penicillamine was determined in a retrospective study." | 3.67 | Eosinophilia in rheumatoid patients treated with D-penicillamine. ( Edelman, J; Maguire, KF; Owen, ET, 1984) |
| "Plasma concentrations were measured in 10 patients with rheumatoid arthritis taking 250 mg, 500 mg and 750 mg of D-penicillamine daily." | 3.67 | Dose, plasma concentration and response relationships of D-penicillamine in patients with rheumatoid arthritis. ( Birkett, DJ; Brooks, PM; Fearnley, I; Miners, JO; Smith, K; Smith, MD, 1984) |
| "Forty-five patients with active rheumatoid arthritis (RA) were treated with D-Penicillamine (DPA), zinc sulphate or trien for 24 weeks." | 3.67 | A comparison of therapies which may influence trace metals in rheumatoid arthritis. ( Bird, HA; Dixon, JS; Sitton, NG; Surrall, KE; Wright, V, 1984) |
| "Large differences exist in the maintenance doses of penicillamine that clinicians regard as effective and safe in rheumatoid arthritis." | 3.67 | Clinical response in relation to dose of penicillamine in the treatment of rheumatoid arthritis. ( Lyle, WH, 1984) |
| "Dermatomyositis developed during treatment with penicillamine in two patients with rheumatoid arthritis." | 3.67 | Penicillamine-induced myositis. Observations and unique features in two patients and review of the literature. ( Fallahi, S; Halla, JT; Koopman, WJ, 1984) |
| "During the period 1976-1983, 67 patients with rheumatoid arthritis attending the arthritis clinics at Groote Schuur Hospital and Princess Alice Orthopaedic Hospital, Cape Town, were treated with penicillamine." | 3.67 | Penicillamine therapy in rheumatoid arthritis. ( Grobbelaar, J; Meyers, OL, 1984) |
| "The pharmacokinetic disposition of D-penicillamine and its major metabolites, penicillamine cysteine disulfide ( PSSC ) and penicillamine disulfide ( PSSP ) has been studied in eight patients with rheumatoid arthritis." | 3.67 | Pharmacokinetics of the major metabolites of D-penicillamine in patients with rheumatoid arthritis. ( Butler, M; Carruthers, G; Freeman, D; Harth, M; Rothwell, R; Weir, D, 1984) |
| "Complexes formed between penicillamine and metal ions have in vitro effects that may have implications regarding the therapeutic action of D-penicillamine in rheumatoid arthritis." | 3.67 | Penicillamine metal chelates and their possible importance in rheumatoid arthritis--a brief review. ( Davis, P, 1984) |
| "The effects of D-penicillamine (D-Pen) in rheumatoid arthritis suggest that the drug may be anti-inflammatory and immunosuppressive." | 3.67 | Effects of D-penicillamine on inflammatory and immune reactions. ( Harth, M; Keown, PA; Orange, JF, 1984) |
| "Penicillamine treatment of rheumatoid arthritis was compared with gold and other remittive agents by reviewing the literature and studying the patients in our penicillamine clinic with respect to their previous responses to chrysotherapy." | 3.67 | Penicillamine and other remittive agents in rheumatoid arthritis: comparisons and interaction. ( Atkins, CJ; Offer, RC; Ruedy, J; Stein, HB, 1984) |
| "Seven of 56 consecutive patients taking penicillamine for rheumatoid arthritis developed oral lesions that clinically and histologically resembled lichen planus." | 3.67 | Lichenoid lesions of the oral mucosa in rheumatoid arthritis patients treated with penicillamine. ( Blasberg, B; Chalmers, A; Conklin, RJ; Dorey, JL; Stein, HB, 1984) |
| "The mechanism of D-penicillamine induced thrombocytopenia in rheumatoid arthritis was investigated by measuring platelet life-span and platelet production rate in 2 groups of rheumatoid arthritis patients treated with 250-750 mg/day D-penicillamine, 14 with a normal platelet count and 9 with thrombocytopenia (platelet count 50-130 X 10(9)/1)." | 3.67 | Thrombokinetics in patients with rheumatoid arthritis treated with D-penicillamine. ( Brooks, PM; Gallus, AS; Geddes, R; Hill, W; Tampi, R; Thomas, D, 1984) |
| "A 60-year-old man with seropositive rheumatoid arthritis developed rapidly progressive dyspnoea and bilateral pulmonary infiltrates on short exposure to 50 mg penicillamine daily." | 3.67 | Diffuse alveolitis on a small dose of penicillamine. ( Chattopadhyay, C; Shettar, SP; Swinson, DR; Wolstenholme, RJ, 1984) |
| "A small fraction of patients with rheumatoid arthritis and other diseases on D-penicillamine treatment may develop antibodies against the acetylcholine receptor (AChR) and symptoms of myasthenia gravis (MG)." | 3.67 | Fine antigenic specificities of antibodies in sera from patients with D-penicillamine-induced myasthenia gravis. ( Bustarret, AF; D'Anglejan, J; Drosos, AA; Efthimiadis, A; Morel, E; Moutsopoulos, HA; Tzartos, SJ, 1988) |
| "Peculiar nail-changes in a 70-year-old woman with rheumatoid arthritis occurring after approximately 1 year of penicillamine treatment are described." | 3.67 | Nail-changes induced by penicillamine. ( Bjellerup, M, 1989) |
| "Complete heart block with severe Adams-Stokes attacks and polymyositis was observed in a 69-year-old man following 6 weeks penicillamine treatment for suspected rheumatoid arthritis." | 3.67 | Penicillamine-induced polymyositis with complete heart block. ( Christensen, PD; Sørensen, KE, 1989) |
| "A rheumatoid arthritis case is described who developed bullous skin eruption with mucosal involvement after 3 years of treatment with penicillamine." | 3.67 | Penicillamine-induced bullous pemphigoid with pemphigus-like antibodies. ( Brandrup, F; Jepsen, LV; Rasmussen, HB, 1989) |
| "A 65 year old woman with rheumatoid arthritis developed marrow aplasia and jaundice owing to D-penicillamine treatment." | 3.67 | Fatal aplastic anaemia and liver toxicity caused by D-penicillamine treatment of rheumatoid arthritis. ( Caspi, D; Fishel, B; Tishler, M; Yaron, M, 1989) |
| "To elucidate the natural course of gold and penicillamine nephropathy and to facilitate appropriate clinical management 54 patients with rheumatoid arthritis who developed proteinuria during treatment with intramuscular gold thiomalate (21) or oral D penicillamine (33) were studied in detail throughout the whole of their renal illnesses." | 3.67 | The natural course of gold and penicillamine nephropathy: a longterm study of 54 patients. ( Hall, CL, 1989) |
| "A patient on treatment with D-penicillamine developed aphthoid ulcers of the oesophagus, which healed rapidly after withdrawal of this drug." | 3.67 | D-penicillamine-induced oesophageal ulcers. ( Ramboer, C; Verhamme, M, 1989) |
| "Serum amyloid A protein (SAA), serum C-reactive protein (CRP) and the ESR were measured in 19 patients with rheumatoid arthritis before treatment and during therapy with gold, penicillamine or sulphasalazine for a mean period of 14." | 3.67 | Serum amyloid A protein during the treatment of rheumatoid arthritis with second-line drugs. ( Bacon, PA; Grindulis, KA; McConkey, B; Robinson, MW; Scott, DL, 1985) |
| "Groups of 15 patients with active rheumatoid arthritis have been treated with sulphasalazine, (salazosulfapyridine INN), zinc sulfate, captopril or methyl cysteine, and assessed by seven clinical measurements and six laboratory methods on eight occasions during a 24-week treatment period." | 3.67 | Biochemical and clinical changes occurring during the treatment of rheumatoid arthritis with novel antirheumatoid drugs. ( Bird, HA; Dixon, JS; Martin, MF; McKenna, F; Wright, V, 1985) |
| "Thirty patients (22 women) with active rheumatoid arthritis participated in an open study of 6 months' treatment with either enteric-coated sulphasalazine (SASP) or SASP plus D-penicillamine (DPA)." | 3.67 | Sulphasalazine alone or in combination with D-penicillamine in rheumatoid arthritis. ( Astbury, C; Bird, HA; Dixon, JS; Hill, J; Taggart, AJ; Wright, V, 1987) |
| "Life-table analysis was applied to the records of 317 patients with rheumatoid arthritis (RA) treated with sulphasalazine (SAS), 201 treated with sodium aurothiomalate (gold), and 163 with penicillamine." | 3.67 | Long-term treatment of rheumatoid arthritis with sulphasalazine, gold, or penicillamine: a comparison using life-table methods. ( Grindulis, KA; McConkey, B; Situnayake, RD, 1987) |
| "Forty-two patients with active rheumatoid arthritis treated with hydroxychloroquine sulphate (400 mg day-1) for six months have been compared with patients treated with D-penicillamine (n = 14), aurothiomalate (n = 13), sulphasalazine (n = 15) and chloroquine (n = 17) to compare the changes in articular index, plasma viscosity and ESR." | 3.67 | How reliable is ESR as a measure of disease activity in rheumatoid arthritis treated with hydroxychloroquine? ( Bird, HA; Dixon, JS; Greenwood, M, 1988) |
| "A 57-year-old patient with rheumatoid arthritis, who was being treated with D-penicillamine, developed a bullous eruption 2 months after the onset of treatment." | 3.67 | [Pemphigus herpetiformis following D-penicillamine in a patient with HLA B8]. ( David, M; Ingber, A; Sandbank, M; Weltfriend, S, 1988) |
| "The mechanism by which D-Penicillamine is effective in the treatment of rheumatoid arthritis has been investigated." | 3.67 | Suggested mode of action of D-penicillamine as an immunosuppressive agent in rheumatoid arthritis. ( Lipsky, PE, 1988) |
| "The capacity of monocytes from patients with rheumatoid arthritis to generate superoxide anion in vitro after stimulation with serum treated zymosan (STZ) or IgG treated zymosan (IgTZ) was studied before and during therapy with penicillamine (n = 9) or sodium aurothiomalate (AuTM) (n = 12)." | 3.67 | Studies of the effect of D-penicillamine and sodium aurothiomalate therapy on superoxide anion production by monocytes from patients with rheumatoid arthritis: evidence for in vivo stimulation of monocytes. ( Bell, AL; Hurst, NP; Nuki, G, 1986) |
| "Synovial needle biopsy specimens from the knee joints of seven patients with rheumatoid arthritis (RA) were examined immunohistochemically before and after six months' treatment with either gold or penicillamine (disease modifying drugs, DMDs)." | 3.67 | An investigation of the action of disease modifying antirheumatic drugs on the rheumatoid synovial membrane: reduction in T lymphocyte subpopulations and HLA-DP and DQ antigen expression after gold or penicillamine therapy. ( Cawley, MI; Evans, PR; Moore, K; Smith, JL; Walters, MT, 1987) |
| "The acetylator phenotype was determined in 59 patients with classical, seropositive and erosive rheumatoid arthritis (RA) treated with sodium-aurothiomalate or d-penicillamine." | 3.67 | Acetylator phenotypes in rheumatoid arthritis patients with or without adverse drug reactions to sodium-aurothiomalate or d-penicillamine. ( Mjörndal, T; Rantapää Dahlqvist, S, 1987) |
| "A longitudinal study of changes in rheumatoid factor levels and their correlations with other clinical and laboratory assessment of disease activity followed 45 rheumatoid arthritis patients during 12 months continuous therapy with gold and penicillamine." | 3.67 | ELISA assays for IgM and IgG rheumatoid factors: their clinical correlations during therapy with slow-acting anti-rheumatic drugs. ( Collins, M; Dawes, PT; Scott, DL; Stone, R, 1987) |
| "To elucidate the natural course of the nephropathy associated with penicillamine and thereby facilitate its clinical management 33 patients with rheumatoid arthritis who developed proteinuria during treatment with oral penicillamine were studied in detail throughout their renal illness." | 3.67 | Natural course of penicillamine nephropathy: a long term study of 33 patients. ( Bacon, PA; Hall, CL; Harrison, PR; Jawad, S; Klouda, PT; MacIver, AG; MacKenzie, JC, 1988) |
| "Ninety-five rheumatoid arthritis patients treated with aurothiomalate and/or D-penicillamine have been studied for possible associations between HLA-A, -B, -DR antigens and various toxic reactions to the above drugs." | 3.67 | HLA-A,-B, and -DR antigens in relation to gold and D-penicillamine toxicity in Greek patients with RA. ( Boki, K; Economidou, J; Fostiropoulos, G; Kappos-Rigatou, I; Pachoula-Papasteriades, C; Varla-Leftherioti, M, 1986) |
| "This study concerns 69 patients with rheumatoid arthritis (RA) and having received successively D-penicillamine (DP) then, after a mean period of 2 years, tiopronin (TP) at a daily dose of 1,500 mg." | 3.67 | [Tiopronin in 69 cases of rheumatoid polyarthritis treated earlier with D-penicillamine]. ( Maisonneuve, H; Maugars, Y; Prost, A; Sigaud, M, 1988) |
| "The effects of long-term aurothiomalate and D-penicillamine treatments on renal function and the urinary excretion of prostanoids were studied in 20 patients with classic or definite rheumatoid arthritis." | 3.67 | Effects of long-term aurothiomalate and D-penicillamine treatments on renal function and urinary excretion of prostanoids in patients with rheumatoid arthritis. ( Harmoinen, A; Isomäki, H; Koivula, T; Lehtinen, K; Mörsky, P; Nissilä, M; Seppälä, E; Vapaatalo, H, 1988) |
| " proteinuria, haematological abnormalities, stomatitis, diarrhoea and dermatitis) in rheumatoid arthritis (RA) to sodium aurothiomalate (gold) and to D-penicillamine (PA) were studied in 32 patients." | 3.67 | HLA antigens and adverse drug reactions to sodium aurothiomalate and D-penicillamine in patients with rheumatoid arthritis. ( Bjelle, A; Dahlqvist, SR; Möller, E; Ström, H, 1985) |
| "Progressive joint damage characterises rheumatoid arthritis despite treatment with slow-acting drugs such as penicillamine." | 3.67 | Progressive joint damage during penicillamine therapy for rheumatoid arthritis. ( Bryans, R; Greenwood, A; Huskisson, EC; Scott, DL, 1988) |
| "Twenty-six patients with rheumatoid arthritis which was poorly controlled despite high dose D-penicillamine were studied." | 3.67 | The use of a pharmacological indicator to investigate compliance in patients with a poor response to antirheumatic therapy. ( Bird, HA; Feely, MP; Martin, MF; Peaker, S; Pullar, T, 1988) |
| "A 41-year-old woman with rheumatoid arthritis developed massive breast enlargement while taking penicillamine." | 3.67 | Penicillamine induced mammary hyperplasia: report of a case and review of the literature. ( Craig, HR, 1988) |
| "Antibodies to D-penicillamine (DPA) were determined in 25 patients with classic rheumatoid arthritis being treated with DPA." | 3.67 | [Antibodies to D-penicillamine in patients with chronic polyarthritis--diagnostic aid in undesired and insufficient drug effects?]. ( Keitel, W; Storch, W, 1988) |
| " In 27 patients with rheumatoid arthritis, we measured the pulmonary excretion of pentane, a product released during lipid peroxidation." | 3.67 | Breath pentane excretion as a marker of disease activity in rheumatoid arthritis. ( Clapper, M; Humad, S; Skosey, JL; Zarling, E, 1988) |
| "The effects of piroxicam and D-penicillamine on T lymphocytes, NK cell activity and rheumatoid factor production as well as clinical parameters were studied in patients with rheumatoid arthritis." | 3.67 | Effects of piroxicam and D-penicillamine on T lymphocyte subpopulations, natural killer cells and rheumatoid factor production in rheumatoid arthritis. ( Førre, O; Haile, Y; Helgetveit, K; Kåss, E; Thoen, J, 1988) |
| "D-Penicillamine is effective in the treatment of Wilson's disease, cystinuria and rheumatoid arthritis." | 3.67 | [Penicillamine-induced pemphigus]. ( Gleichmann, E; Goerz, G; Kind, P; Plewig, G, 1987) |
| "Aplastic anaemia developed in a 33-year-old woman whose rheumatoid arthritis was refractory to the administration of many drugs, including penicillamine and gold." | 3.67 | Prolonged remission of severe refractory rheumatoid arthritis following allogeneic bone marrow transplantation for drug-induced aplastic anaemia. ( Jacobs, P; Martell, RW; Vincent, MD, 1986) |
| "A retrospective analysis was undertaken of 31 patients with classical or proven chronic rheumatoid arthritis (CRA) who had been on a regimen of basic medication (gold salts, D-penicillamine, chloroquine, azathioprine--alone or in combination)." | 3.67 | [Long-term course of chronic polyarthritis under basic drug therapy]. ( Harder, T; Krahe, T; Leiendecker, U; Mattern, H, 1988) |
| "Free and total reduced concentrations of D-penicillamine have been measured in the plasma of rheumatoid arthritis patients by HPLC and electro-chemical detection." | 3.67 | Identification of factors limiting the accurate measurement of plasma D-penicillamine in rheumatoid arthritis patients. ( Haslock, I; Richardson, SJ; Webb, BA, 1988) |
| "This article summarizes the authors' experience and data from the literature regarding acadione, a medication like D-penicillamine with a thiol radical, in the treatment of rheumatoid arthritis." | 3.67 | [Acadione, a new long-term treatment of rheumatoid polyarthritis]. ( Amor, B; de Gery, A; Mery, C, 1988) |
| "A 51-year-old man developed pemphigus vulgaris, minimal change nephropathy and acute tubular necrosis after 11 months of treatment with penicillamine for rheumatoid arthritis associated with features of Reiter's syndrome." | 3.67 | Minimal change nephropathy and pemphigus vulgaris associated with penicillamine treatment of rheumatoid arthritis. ( Chia, Y; Pusey, CD; Savill, JS, 1988) |
| "To assess therapeutic effect and toxicity of D-penicillamine in relation to HLA antigens, 111 consecutive patients with rheumatoid arthritis (RA) were followed for a period of 7-9 years." | 3.67 | Longterm followup of treatment with D-penicillamine for rheumatoid arthritis: effectivity and toxicity in relation to HLA antigens. ( Ament, BJ; Feltkamp, BW; Moens, HJ; van der Korst, JK, 1987) |
| "In a 3-centre study involving 144 patients with rheumatoid arthritis (RA), a relationship between side effects from D-penicillamine and HLA antigens, allotypic markers of the IgG heavy chain (Gm) and allotypes of complement components Bf, C4A and C4B was sought." | 3.67 | Genetic markers in rheumatoid arthritis relationship to toxicity from D-penicillamine. ( Hannah, MC; Major, GA; Mathews, JD; McCluskey, J; Muirden, KD; Property, DN; Stockman, A; Tait, BD; Zilko, PJ, 1986) |
| "The effect of D-penicillamine (DPA) on immunoreactive prostanoid concentrations was studied in a primary culture of adherent synovial cells from patients suffering from rheumatoid arthritis (RA)." | 3.67 | D-penicillamine effects on prostanoid production in adherent rheumatic synovial cells in primary culture. ( Moilanen, E; Nissilä, M; Seppälä, E; Vapaatalo, H, 1987) |
| "Twenty-six of 300 patients (9%) with rheumatoid arthritis (RA) developed penicillamine-induced proteinuria." | 3.67 | Penicillamine-induced proteinuria: risk factors. ( Dillon, AM; Schroeder, ML; Stein, HB, 1986) |
| "Eight Australian cases of D-penicillamine induced polymyositis/dermatomyositis (PM/DM) are reported." | 3.67 | Penicillamine induced polymyositis and dermatomyositis. ( Carroll, GJ; Dawkins, RL; Garlepp, MJ; Peter, JB; Will, RK, 1987) |
| "A 51-year-old woman with advanced rheumatoid arthritis developed a Goodpasture's syndrome during treatment with penicillamine and carbimazole." | 3.67 | Goodpasture's syndrome in a patient receiving penicillamine and carbimazole. ( Alvarez, J; Arboleya, LR; López-Larrea, C; Peces, R; Riera, JR, 1987) |
| "The authors report three cases of bronchiolitis obliterans occurring during treatment of rheumatoid arthritis with D-penicillamine after 4, 6 and 8 months of treatment and when the rheumatoid arthritis was in a state of remission." | 3.67 | [3 cases of obliterating bronchiolitis during treatment of rheumatoid polyarthritis with D-penicillamine]. ( Bontoux-Carre, E; Racineux, JL; Renier, JC, 1986) |
| "The authors present a series of 120 cases of sero-positive rheumatoid arthritis followed for ten years and treated with D-penicillamine, gold salts and pyrithioxine used either alone or sequentially after stopping one of these treatments because of failure, intolerance or escape." | 3.67 | [Sulfhydryl maintenance treatment in rheumatoid polyarthritis. A series of 120 cases followed for 10 years and a study of possibilities of changing the drug]. ( Camus, JP; Koeger, AC; Laveant, C; Struz, P, 1986) |
| "This article summarises the authors' experience and the data of the literature concerning Tiopronine, a drug with a thiol function like D-penicillamine, in the treatment of rheumatoid arthritis." | 3.67 | [Tiopronine and rheumatoid polyarthritis]. ( Amor, B; de Gery, A; Mery, C; Zizi, M, 1986) |
| "104 patients with rheumatoid arthritis were treated by D-penicillamine and were followed for 5 years after the start of treatment." | 3.67 | [D-penicillamine in the treatment of rheumatoid polyarthritis. 104 cases with a 5-year follow-up]. ( Chantreuil, C; Eveleigh, MC; Fouquet, B; Lalot, F; Valat, JP, 1986) |
| "Among 329 patients with rheumatoid arthritis treated with D-penicillamine (DP), we found 4 cases of polymyositis." | 3.67 | D-penicillamine-induced polymyositis in patients with rheumatoid arthritis. ( Miyamoto, T; Ogita, T; Okudaira, H; Takahashi, K; Yoshinoya, S; Yoshizawa, H, 1986) |
| "Toxic epidermal necrolysis with epidermal shedding over almost the entire body occurred in a patient with classical rheumatoid arthritis treated with sulindac, penicillamine and a combination analgesic containing paracetamol and chlormezanone." | 3.67 | Toxic epidermal necrolysis with extensive mucosal erosions of the gastrointestinal and respiratory tracts. ( Ahlmén, M; Fagerberg, B; Roupe, G; Suurküla, M, 1986) |
| "We have described three patients whose rheumatoid arthritis was exacerbated by penicillamine." | 3.67 | Penicillamine-induced exacerbation of rheumatoid arthritis. ( Butler, D; Tiliakos, NA, 1986) |
| "D-penicillamine and its major metabolites cysteine-penicillamine disulphide (CP) and penicillamine disulphide (P2) concentrations were measured in plasma from a hemodialysis patient with rheumatoid arthritis." | 3.67 | The use of D-penicillamine in patients with rheumatoid arthritis undergoing hemodialysis. ( Baker, LR; Greenwood, RN; Matthey, F; Perrett, D, 1986) |
| "Two surveys carried out by the Epidemiology Team of the French Rheumatology Society (RESFR) were used to assess the treatment of rheumatoid arthritis (RA) by means of D-penicillamine (DP)." | 3.67 | [Surveys of the epidemiological team of the French Rheumatology Society (RESFR) on the prescription of D-penicillamine in the treatment of rheumatoid polyarthritis]. ( Carter, H; Chevallier, J; Ghoussoub, K; Paolaggi, JB, 1986) |
| "Seven cases of myasthenia induced by D-penicillamine treatment of rheumatoid arthritis are presented." | 3.67 | [Myasthenia induced by D-penicillamine during the treatment of rheumatoid polyarthritis]. ( Carter, H; Delrieu, F; Job-Deslandre, C; Kahan, A; Menkès, CJ, 1986) |
| "We have described a unique patient who had reversible and dose-related myasthenia gravis after penicillamine and chloroquine therapy for rheumatoid arthritis." | 3.67 | Myasthenia gravis caused by penicillamine and chloroquine therapy for rheumatoid arthritis. ( Hearn, J; Tiliakos, NA, 1986) |
| "The case of a 57-year-old woman with rheumatoid arthritis is presented to illustrate the rare occurrence of a myasthenic syndrome induced by D-penicillamine, which led to prolonged (5." | 3.67 | D-penicillamine induced myasthenia gravis. Its relevance for the anaesthetist. ( Fried, MJ; Protheroe, DT, 1986) |
| "A 68 year old man with rheumatoid arthritis developed marrow aplasia during D-penicillamine treatment." | 3.67 | Acquired sideroblastic anaemia after aplastic anaemia caused by D-penicillamine therapy for rheumatoid arthritis. ( Bijlsma, JW; Dekker, AW; Huber-Bruning, O; Ramselaar, AC, 1987) |
| "One hundred and forty-one patients with rheumatoid arthritis treated with aurothiopropanol sulphonate or D-penicillamine, or both were examined for HLA antigens to investigate the genetic influence on the occurrence of different adverse reactions during therapy." | 3.67 | HLA antigens and toxic reactions to sodium aurothiopropanol sulphonate and D-penicillamine in patients with rheumatoid arthritis. ( Busson, M; Gaucher, A; Perrier, P; Raffoux, C; Streiff, F; Tamisier, JN; Thomas, P, 1985) |
| "We assessed the immunoglobulin secretory capacity of circulating B lymphocytes in 9 patients with classical rheumatoid arthritis (RA) before and after treatment with D-penicillamine." | 3.67 | D-penicillamine induced suppression of B cell function: in vivo effect of D-penicillamine. ( Clancy, RL; Cripps, AW; Glass, JS; Lewins, EG; Major, GA, 1985) |
| "HLA phenotype frequencies were studied in 21 rheumatoid arthritis (RA) patients with haematotoxic reactions to aurothioglucose (AuTG) or D-penicillamine (DP), 65 matched RA controls and 277 healthy controls." | 3.67 | HLA associations in aurothioglucose- and D-penicillamine-induced haematotoxic reactions in rheumatoid arthritis. ( Reekers, P; Speerstra, F; van de Putte, LB; Vandenbroucke, JP, 1985) |
| "A patient developed both ankylosing spondylitis and rheumatoid arthritis, each of which responded to D-penicillamine or gold sodium thiomalate and indomethacin, respectively." | 3.67 | Ankylosing spondylitis and rheumatoid arthritis in a patient with Paget's disease. Differential effects of indomethacin, D-penicillamine, or gold sodium thiomalate in the respective arthritides. ( Alarcón-Segovia, D; Martínez-Cordero, E, 1985) |
| "One hundred and fifty consecutive patients with active, rheumatoid arthritis were assessed and treated with gold, D-penicillamine, chloroquine or dapsone." | 3.67 | Rheumatoid arthritis: treatment which controls the C-reactive protein and erythrocyte sedimentation rate reduces radiological progression. ( Clarke, S; Dawes, PT; Fisher, J; Fowler, PD; Lawton, A; Shadforth, MF, 1986) |
| "Long-term therapy of D-penicillamine (D-Pen) for rheumatoid arthritis (RA) is associated with a fall in rheumatoid factor, but many patients develop autoantibodies." | 3.67 | Increased binding of D-penicillamine to monocytes in rheumatoid arthritis. ( Dawkins, RL; Grimsley, G; Major, GA; Watanabe, H, 1986) |
| "A 49 year old man with rheumatoid arthritis developed a proliferative glomerulonephritis with progressive renal impairment during treatment with D-penicillamine." | 3.67 | Progressive proliferative glomerulonephritis in a patient with rheumatoid arthritis treated with D-penicillamine. ( Barnes, CG; Fordham, JN; Goodwin, FJ; Williams, AJ, 1986) |
| "In this report we describe the development of idiopathic nephrotic syndrome with an IgM nephropathy in a 53-year-old patient undergoing treatment for active rheumatoid arthritis with D-penicillamine." | 3.67 | IgM nephropathy associated with penicillamine. ( Johnson, K; Rehan, A, 1986) |
| "In a patient receiving penicillamine for treatment of rheumatoid arthritis, antibodies to insulin developed, which resulted in symptomatic hypoglycemia." | 3.67 | Insulin antibodies in patients receiving penicillamine. ( Barron, EJ; Benson, EA; Healey, LA, 1985) |
| "A male aged 72 years suffering from erosive seropositive rheumatoid arthritis developed jaundice after one month on D-penicillamine after a cumulative dose of 5." | 3.67 | A case of cholestatic hepatitis associated with D-penicillamine therapy for rheumatoid arthritis. ( Coche, E; Devogelaer, JP; Huaux, JP; Nagant de Deuxchaisnes, C; Rahier, J, 1985) |
| "A patient with advanced rheumatoid arthritis and severe clinical manifestations of rheumatoid vasculitis died of acute renal failure after 30 months of treatment with high-dosage D-penicillamine." | 3.67 | Rapidly progressive glomerulonephritis in a patient with rheumatoid arthritis during treatment with high-dosage D-penicillamine. ( Berger, AR; Milstoc, M; Sadjadi, SA; Seelig, MS, 1985) |
| "Three cases of D-penicillamine (DPA) induced myasthenia gravis (MG) and one case of DPA-induced polymyositis (PM) are reported among four patients suffering from seropositive rheumatoid arthritis." | 3.67 | Neuromuscular disorders associated with D-penicillamine treatment for rheumatoid arthritis. ( De Bruyère, M; Devogelaer, JP; Huaux, JP; Isaac, G; Nagant de Deuxchaisnes, C; Noël, H, 1985) |
| "A patient receiving d-penicillamine for rheumatoid arthritis developed a lymphoma, therapy for which resulted not only in haematological resolution but marked remission of rheumatoid disease activity, including radiological improvement." | 3.67 | Remission of arthritis and radiological improvement after combination therapy for non-Hodgkin's lymphoma in a patient with rheumatoid arthritis undergoing treatment with D-penicillamine. ( Sheldon, P; Wood, JK, 1985) |
| "In view of the claim that alclofenac has a specific antirheumatoid action a detailed biochemical study has been made over a 6-month period of 2 groups of patients with rheumatoid arthritis receiving either alclofenac or D-penicillamine for the first time." | 3.66 | A biochemical comparison of alclofenac and D-penicillamine in rheumatoid arthritis. ( Bird, HA; Dixon, JS; Lee, MR; Pickup, ME; Wright, V, 1980) |
| "7 of 16 patients with rheumatoid arthritis in whom penicillamine glomerulonephritis had developed had been taking oral iron, usually without the knowledge of their hospital clinician, while the dose of penicillamine was being gradually increased to an effective level." | 3.66 | Penicillamine nephropathy and iron. ( Blake, DR; Harkness, JA, 1982) |
| "Cross-sectional and longitudinal studies have been carried out to determine the incidence and clinical significance of eosinophilia in patients taking penicillamine for rheumatoid arthritis." | 3.66 | Eosinophilia in D-penicillamine therapy. ( Scott, DL; Smith, DH; Zaphiropoulos, GC, 1983) |
| "Ninety patients with rheumatoid arthritis who had received courses of gold followed by penicillamine for their disease were evaluated to determine the predictiveness of a certain response or adverse reaction to gold for the same response or adverse reaction to penicillamine." | 3.66 | Sequential gold and penicillamine therapy in rheumatoid arthritis. ( Cassady, J; Halla, JT; Hardin, JG, 1982) |
| "One hundred fourteen patients with definite or classic rheumatoid arthritis were followed prospectively between January 1976 and April 1981 to monitor their toxicity pattern to D-penicillamine." | 3.66 | Prior gold therapy does not influence the adverse effects of D-penicillamine in rheumatoid arthritis. ( Buchanan, WW; Howard-Lock, HE; Kean, WF; Lock, CJ, 1982) |
| "Skin rashes, proteinuria, systemic lupus erythematosus, polymyositis and myasthenia gravis have all been recorded as complications of penicillamine therapy in patients with rheumatoid arthritis." | 3.66 | Multiple side effects of penicillamine therapy in one patient with rheumatoid arthritis. ( Essigman, WK, 1982) |
| "Electroneuromyographic studies have been reported as abnormal in only 9 of 23 cases of penicillamine-associated myasthenia gravis (MG)." | 3.66 | Penicillamine-associated myasthenia gravis. ( Albers, JW; Hodach, RJ; Kimmel, DW; Treacy, WL, 1980) |
| "Electroneuromyographic studies were performed on patients with rheumatoid arthritis, some of whom were received penicillamine, to determine whether a subclinical defect of neuromuscular transmission existed." | 3.66 | Neuromuscular transmission in rheumatoid arthritis, with and without penicillamine treatment. ( Albers, JW; Beals, CA; Levine, SP, 1981) |
| "Polyneuropathy occurring during therapy with D-penicillamine is reported in a 63 year-old women with chronic rheumatoid arthritis." | 3.66 | [A chemically induced polyneuropathy in chronic polyarthritis treated with D-penicillamine?]. ( Graninger, W; Mayr, N; Wessely, P, 1983) |
| "A series of thirty patients with rheumatoid arthritis in whom D-penicillamine therapy was initiated more than five years ago was analyzed." | 3.66 | [5-year treatment of rheumatoid polyarthritis with D-penicillamine]. ( Cocheteux, P; Delcambre, B; Duquesnoy, B; Siame, JL, 1983) |
| "Rapidly progressive glomerulonephritis occurred in a woman with rheumatoid arthritis (RA) who had been treated with D-penicillamine for 3 months." | 3.66 | Extracapillary glomerulonephritis with necrotizing vasculitis in D-penicillamine-treated rheumatoid arthritis. ( Banfi, G; Guerra, L; Imbasciati, E; Mihatsch, MJ; Ponticelli, C, 1983) |
| "Groups of 15 patients with active rheumatoid arthritis were treated for 24 weeks with zinc sulphate, trien, captopril, clozic in two doses or a combination of D-penicillamine and hydroxychloroquine." | 3.66 | The effect of drugs on serum histidine levels in rheumatoid arthritis. ( Bird, HA; Dixon, JS; Martin, MF; Pickup, ME; Sitton, NG; Surrall, KE, 1983) |
| "Antibodies to the acetylcholine receptor and HLA antigens have been studied in patients with myasthenia gravis occurring in association with penicillamine treatment." | 3.66 | HLA antigens and acetylcholine receptor antibodies in penicillamine induced myasthenia gravis. ( Christiansen, FT; Dawkins, RL; Garlepp, MJ, 1983) |
| "By means of a case-control study we investigated the association between HLA phenotypes and the development of proteinuria after aurothioglucose or D-penicillamine treatment in patients with rheumatoid arthritis (RA)." | 3.66 | HLA-DR antigens and proteinuria induced by aurothioglucose and D-penicillamine in patients with rheumatoid arthritis. ( de Rooij, DJ; Rasker, JJ; Reekers, P; Speerstra, F; van de Putte, LB; Vandenbroucke, JP, 1983) |
| "A 44-year-old woman with rheumatoid arthritis and vasculitis of the skin developed a lupus erythematosus-like reaction after 5 weeks of D-penicillamine therapy." | 3.66 | Penicillamine-induced lupus-like reaction in rheumatoid arthritis and vasculitis. ( Thorvaldsen, J, 1981) |
| "The clinical features and genetic background of 18 patients with rheumatoid arthritis were investigated following the development of penicillamine-induced myasthenia (PIM)." | 3.66 | Penicillamine-induced myasthenia in rheumatoid arthritis: its clinical and genetic features. ( Delamere, JP; Jobson, S; Mackintosh, LP; Walton, KW; Wells, L, 1983) |
| "Histological, immunohistological and electron microscopical investigations on the glomerular renal lesions in penicillamine-induced nephropathy were carried out by studying biopsy material of eight patients with rheumatoid arthritis (4 cases), allergic alveolitis (3 cases) and systemic scleroderma (1 case) under the treatment with D-penicillamine." | 3.66 | [Morphology and pathogenesis of penicillamine-induced nephropathy]. ( Henzgen, S; Waldmann, G, 1983) |
| "Diffuse fasciculations developed in a patient with rheumatoid arthritis who had received D-penicillamine for 6 months." | 3.66 | Diffuse fasciculations induced by D-penicillamine. ( Pinals, RS, 1983) |
| "Over recent years, several cases have been reported of bronchiolitis obliterans, of very rapid onset and serious clinical course in patients with rheumatoid arthritis being treated with D-Penicillamine." | 3.66 | [Rheumatoid arthritis, obliterating bronchiolitis and D-penicillamine. Apropos of a new case with ultrastructural examination and review of the literature]. ( Blanc-Jouvan, F; Brambilla, E; Geraads, A; Hohn, B; Kamel, A; Piton, JL, 1983) |
| "A 69-year-old woman with classical rheumatoid arthritis developed a severe dermato-myopathy during treatment with penicillamine." | 3.66 | Penicillamine-induced dermatomyositis. A case history. ( Lund, HI; Nielsen, M, 1983) |
| "Penicillamine is now established as a useful disease remittive drug in the treatment of rheumatoid arthritis." | 3.66 | Penicillamine: an anti-rheumatoid drug. ( Jaffe, IA, 1983) |
| "Forty-four patients with definite or classical rheumatoid arthritis were entered in a 48-week open study, comparing the long-term effects of Timegadine and D-penicillamine." | 3.66 | A comparative trial of timegadine and D-penicillamine in rheumatoid arthritis. ( Dequeker, J; Mbuyi-Muamba, JM, 1983) |
| "Thrombotic thrombocytopenic purpura (TTP) developed in a patient with seropositive rheumatoid arthritis (RA) after 2 1/2 months of treatment with penicillamine." | 3.66 | Thrombotic thrombocytopenic purpura during penicillamine therapy in rheumatoid arthritis. ( Pinals, RS; Plitman, GI; Trice, JM, 1983) |
| "To investigate the possible relation between certain HLA antigens and toxicity during treatment with sodium aurothiomalate of D-penicillamine, we studied 91 patients with rheumatoid arthritis." | 3.66 | HLA-DR antigens and toxic reaction to sodium aurothiomalate and D-penicillamine in patients with rheumatoid arthritis. ( Batchelor, JR; Gibson, TJ; Griffin, J; Panayi, GS; Welsh, KI; Wooley, PH, 1980) |
| "The incidence of adverse reactions to D-penicillamine in 155 patients with rheumatoid arthritis was analysed and compared with their history of adverse reactions to gold." | 3.66 | Adverse reactions to D-penicillamine after gold toxicity. ( Dodd, MJ; Griffiths, ID; Thompson, M, 1980) |
| "Myositis was diagnosed twenty months after starting treatment with d-penicillamine in a patient suffering from uncomplicated rheumatoid arthritis for nearly three years." | 3.66 | [Is myositis in chronic polyarthritis using d-penicillamine drug-induced?]. ( Bussmann, HU; Jerusalem, F; Schlumpf, U, 1981) |
| "Over a 5-year period 325 patients with rheumatoid arthritis received treatment with gold (162) or D-penicillamine (163)." | 3.66 | Proteinuria in rheumatoid arthritis--drug-induced or amyloid? ( Bourke, BE; Scott, JT; Woodrow, DF, 1981) |
| "Sixty patients with active rheumatoid arthritis (mean ESR = 51 mm/h) were treated for six months with D-penicillamine (15 patients), sodium aurothiomalate (15 patients), hydroxychloroquine (15 patients) or enteric-coated aspirin (15 patients)." | 3.66 | Enteric-coated aspirin in rheumatoid arthritis. ( Bird, HA; Leatham, P; Rhind, V; Saunders, A; Wright, V, 1981) |
| "Immunoglobulins (IgG, IgA, IgM) have been measured by radial immunodiffusion method in 43 patients affected with rheumatoid arthritis and treated with d-penicillamine (Pen)." | 3.66 | [Effect of D-penicillamine on serum immunoglobulins in rheumatoid arthritis]. ( Gambari, PF; Mioni, E; Ongaro, G; Ostuni, A; Punzi, L; Todesco, S; Volante, D, 1981) |
| "Thirteen reports of patients who developed polymyositis or dermatomyositis during treatment with D-penicillamine are reviewed and a fourteenth case is described." | 3.66 | Fatal polymyositis in D-penicillamine-treated rheumatoid arthritis. ( Doyle, DR; McCurley, TL; Sergent, JS, 1983) |
| "Penicillamine treatment of patients with rheumatoid arthritis (RA) leads to falling titers of agglutinating IgM rheumatoid factor (RF), but its effect on IgG RF has not been described." | 3.66 | IgG and IgM rheumatoid factors in rheumatoid arthritis. Quantitative response to penicillamine therapy and relationship to disease activity. ( Jaffe, I; Merryman, P; Wernick, R; Ziff, M, 1983) |
| "Four of 133 patients with rheumatoid arthritis suddenly developed progressive respiratory symptoms while receiving penicillamine therapy." | 3.66 | Upper and lower airway disease in penicillamine treated patients with rheumatoid arthritis. ( James, DL; Lin, JJ; Montgomery-Short, R; Polland, SM; Schurle, DR; Smith, TW; Wolfe, F, 1983) |
| "The prevalence of autoimmune associations was determined in 113 patients with primary biliary cirrhosis who participated in a therapeutic trial of D-penicillamine." | 3.66 | Autoimmune associations in primary biliary cirrhosis. ( Baldus, WP; Culp, KS; Dickson, ER; Duffy, J; Fleming, CR, 1982) |
| "Six patients with rheumatoid arthritis developed a syndrome resembling lupus erythematosus while being treated with penicillamine." | 3.66 | Systemic lupus erythematosus during penicillamine therapy for rheumatoid arthritis. ( Chalmers, A; Patterson, AC; Reid, G; Stein, HE; Thompson, D, 1982) |
| "Among 67 patients with rheumatoid arthritis treated with gold salts (aurothiopropanol sulphonate) a significant correlation (p less than 10(-2)) was noted between gold toxic reactions, whatever their type, and the HLA antigens A1, B8, Cw7, and DR3." | 3.66 | HLA system and side effects of gold salts and D-penicillamine treatment of rheumatoid arthritis. ( Bardin, T; Dausset, J; Debeyre, N; Dryll, A; Legrand, L; Marcelli, A; Ryckewaert, A, 1982) |
| "Eighteen of 24 patients with rheumatoid arthritis showed intermediate IgG-containing complexes on preparative ultracentrifugation before treatment with D-penicillamine." | 3.66 | Circulating protein complexes in D-penicillamine therapy of rheumatoid arthritis. Correlation between IgG- and alpha 1-antitrypsin-IgA complexes and clinical response. ( Gedda, PO; Norberg, R; Wollheim, FA, 1980) |
| "Penicillamine-associated bullous eruptions share with spontaneously occurring pemphigus intraepidermal acantholysis, epidermal intercellular deposition of immunoglobulin, and circulating serum antibody against the intercellular regions of the epidermis." | 3.66 | Penicillamine-associated pemphigus: is it really pemphigus? ( Grossman, ME; Jaffe, IA; Silvers, DN; Troy, JL, 1981) |
| " It occurred in a 73-year-old woman who suffered from rheumatoid arthritis and had previously demonstrated gold intolerance." | 3.66 | D-Penicillamine-induced severe pneumonitis. ( Camus, P; Degat, OR; Jeannin, L; Justrabo, E, 1982) |
| "Immunological and electrophysiological features were investigated in a patient with rheumatoid arthritis who developed myasthenic symptoms after 10 months of treatment with D-penicillamine (D-pen)." | 3.66 | D-Penicillamine-associated myasthenia gravis: immunological and electrophysiological studies. ( Argov, Z; Fawcett, PR; Mastaglia, FL; McLachlan, SM; Nicholson, LV, 1982) |
| "One hundred patients with definite or classical rheumatoid arthritis were commenced on gold or penicillamine therapy." | 3.66 | Gold and penicillamine therapy: is shared care with general practitioners effective and safe? ( Capell, HA; Hunter, JA; Pullar, T, 1982) |
| "Fifty-seven patients took part in a controlled double-blind trial between tiopronin and D-penicillamine as basic treatment for rheumatoid arthritis." | 3.66 | Controlled multicenter trial of tiopronin and d-penicillamine for rheumatoid arthritis. ( Ambanelli, U; Barbieri, P; Ciompi, ML; Colamussi, V; Ferraccioli, G; Mazzoni, MR; Menegale, G; Pasero, G; Pellegrini, P; Trippi, D, 1982) |
| "Twenty-five patients with rheumatoid arthritis treated with D-penicillamine were retrospectively reviewed for signs of drug intolerance." | 3.66 | The relationship between D-penicillamine--induced proteinuria and prior gold nephropathy. ( Billingsley, LM; Stevens, MB, 1981) |
| "The development of pemphigus foliaceus in three patients and pemphigus erythematosus in one patient with rheumatoid arthritis treated with penicillamine is described." | 3.66 | Pemphigus in rheumatoid arthritis treated with penicillamine. ( Livden, JK; Milde, EJ; Naevdal, A, 1981) |
| "The authors report on 2 personal cases, and review 48 published cases of myasthenia induced by D-penicillamine (D-P) treatment in patients with rheumatoid arthritis." | 3.66 | [D-penicillamine induced myasthenic syndromes in rheumatoid arthritis. Two cases (author's transl)]. ( Cler, JM; Cottin, S; Hamelin, JP; Lemouroux, P; Rodat, G; Rodat, O; Rossard, A, 1981) |
| "The action of D-penicillamine on collagen can cause undesired side-effects in the treatment of cystinuria and Wilson's disease, it is on the other hand essential to the therapy of rheumatoid arthritis and scleroderma." | 3.66 | D-penicillamine in pregnancy--to ban or not to ban? ( Endres, W, 1981) |
| "This article reports some observations made in a woman who developed myasthenia gravis after treatment with D-penicillamine." | 3.66 | Penicillamine-induced myasthenia gravis in a patient with rheumatoid arthritis. A case report. ( Naidoo, PD, 1981) |
| "D-penicillamine has proved to be an effective treatment of rheumatoid arthritis, but adverse effects of this drug are frequent." | 3.66 | [Respiratory complications in the course of treatment with D-penicillamine : alveolitis and bronchiolitis. A report of 4 cases (author's transl)]. ( Brune, J; Cordier, JF; Moulin, G; Moulin, J; Touraine, R, 1981) |
| "D-penicillamine is a potent drug used to treat rheumatoid arthritis, Wilson's disease and cystinuria." | 3.66 | D-penicillamine and the ocular myasthenic syndrome. ( Kimbrough, RL; Mewis, L; Stewart, RH, 1981) |
| "Adverse effects to D-penicillamine were studied prospectively over 3 years in 259 patients with rheumatoid arthritis." | 3.66 | Adverse effects of D-penicillamine in rheumatoid arthritis. ( Atkins, CJ; Offer, RC; Patterson, AC; Robinson, HS; Stein, HB; Teufel, A, 1980) |
| "One hundred and one patients with rheumatoid arthritis were followed prospectively to assess the efficacy and toxicity of therapy with D-penicillamine." | 3.66 | The toxicity pattern of D-penicillamine therapy. A guide to its use in rheumatoid arthritis. ( Anastassiades, TP; Dwosh, IL; Ford, PM; Kean, WF; Kelly, HG, 1980) |
| "The authors describe a new original observation of a D-penicillamine-induced pemphigus in a patient with rheumatoid polyarthritis." | 3.66 | [D-penicillamine-induced pemphigus]. ( Bathias, J; Chouvet, B; Forestier, JY; Thivolet, J, 1980) |
| "Out of 64 patients with rheumatoid arthritis (RA), 42 were treated with D-penicillamine (D-Pa) for more than 6 months and 22 for less than 6 months." | 3.66 | Penicillamine treatment in rheumatoid arthritis. A retrospective study. ( Börjesson, O; Knutsson, LP; Svensson, B, 1980) |
| "A study of patients with rheumatoid arthritis permitted us to note the interest of tiopronine (sulfhydryl compound of the d-penicillamine type) in the basic treatment of rheumatoid arthritis." | 3.66 | [Tiopronine: new basic treatment for rheumatoid arthritis. Open study of 158 cases]. ( Barbieri, P; Ciompi, ML; Colamussi, V; Mazzoni, MR; Pasero, G; Pellegrini, P, 1980) |
| "Six clinical assessments of disease activity, including a new summated change scale (SCS), have been compared in a group of 30 patients with rheumatoid arthritis seen on 8 separate occasions during their first 6 months of therapy with either D-penicillamine or hydroxychloroquine." | 3.66 | A comparison of clinical assessments of disease activity in rheumatoid arthritis. ( Bird, HA; Rhind, VM; Wright, V, 1980) |
| "Two patients with rheumatoid arthritis developed evidence of hepatotoxicity while receiving D-penicillamine." | 3.66 | Hepatotoxicity associated with use of D-penicillamine in rheumatoid arthritis. ( Katz, WA; Rosenbaum, J; Schumacher, HR, 1980) |
| " Penicillamine-induced myasthenia gravis in a patient with rheumatoid arthritis." | 3.66 | [Prolonged neuromuscular blockade during a D. penicillamine-induced myasthenia (author's transl)]. ( Baron, D; Blanloeil, Y; Gazeau, MF; Nicolas, F, 1980) |
| "Following one-week treatment with D-penicillamine for rheumatoid arthritis a seven-year-old girl died with the clinical features of protracted circulatory shock." | 3.66 | [Administration of D-penicillamine instead of penicillin with fatal results: allergy of the delayed type with protracted shock as fatal complication of treatment with D-penicillamine for rheumatoid arthritis in a child (author's transl)]. ( Adebahr, G; Erkrath, KD; Klöppel, A, 1980) |
| "8 patients who developed proteinuria whilst receiving penicillamine for rheumatoid arthritis have been studied." | 3.66 | Penicillamine nephropathy. ( Brewer, DG; McGinty, F; Ross, JH, 1980) |
| "A case of dermatomyositis is reported in a 50-year-old woman receiving D-Penicillamine therapy for rheumatoid arthritis." | 3.66 | Dermatomyositis induced by penicillamine. ( Golding, JR; Simpson, NB, 1979) |
| "Although in common use, there is still controversy as to the way in which gold and penicillamine act in rheumatoid arthritis (RA)." | 3.66 | Gold and penicillamine: a proposed mode of action in rheumatoid arthritis, based on synovial fluid analysis. ( Nuki, G; Pritchard, MH, 1978) |
| "The results of electron microscopic examination of renal biopsies from 3 patients with rheumatoid arthritis treated with penicillamine are presented." | 3.66 | Simultaneous occurrence of perimembranous glomerulonephritis and glomerular amyloidosis. ( Bohle, A; Fischbach, H; Gärtner, HV; Helmchen, U; Potjan, K; von Gise, H; Wildhirt, E, 1978) |
| "2 women, 62 and 69 years old, both suffering from rheumatoid arthritis, were treated for 1 and 1 1/2 years, respectively, with penicillamine." | 3.66 | Two cases of penicillamine-induced pemphigus erythematosus. ( Thorvaldsen, J, 1979) |
| "Dense, granular immunoglobulin deposits have been identified at the epidermo-dermal junction in 4 out of 10 patients who developed toxic reactions to D-penicillamine therapy for rheumatoid arthritis." | 3.66 | D-penicillamine and immune complex deposition. ( Dieppe, PA; Huskisson, EC; Kirby, JD; Smith, B, 1979) |
| "While D-Penicillamine is effective in the treatment of rheumatoid arthritis, its mechanism of action is unknown." | 3.66 | Effects of D-penicillamine on lymphocyte modulation of synovial collagenase production. ( DeVore, DP; Gruebel, RJ; Hutson, TB; Turner, RH, 1979) |
| "Liver enzymes were followed in 99 patients treated with D-penicillamine for rheumatoid arthritis." | 3.66 | Liver abnormalities in penicillamine treated rheumatoid arthritis. ( Lindström, CG; Wollheim, FA, 1979) |
| " D-Penicillamine suppresses the immuno-inflammatory process of rheumatoid arthritis, which indirectly may lead to a depression of the stimuli perpetuating the proliferative lesion." | 3.66 | Proliferative lesion of arthritis: a target for therapy? ( Van Beusekom, HJ; Van De Putte, LB, 1979) |
| "The difficulties encountered in administering D-penicillamine to 40 patients with rheumatoid arthritis (RA) over a six to 24 month period are recorded." | 3.66 | Difficulties in the use of D-penicillamine in the treatment of rheumatoid arthritis. ( Barraclough, D; Kincaid-Smith, P; Macdonald, I; Muirden, KD; Richter, D; Stockman, A, 1979) |
| "28 patients with rheumatoid arthritis undergoing treatment with penicillamine were investigated over a period of 7 to 72 months." | 3.66 | [Are antinuclear factors a contraindication for penicillamine treatment in patients with rheumatoid arthritis? (author's transl)]. ( Hiesberger, H; Kolarz, G; Scherak, O, 1978) |
| "Characteristics of patients on penicillamine therapy for rheumatoid arthritis were correlated with the occurrence of different side-effects." | 3.66 | Factors affecting the development of penicillamine side-effects. ( Corke, CF; Huskisson, EC, 1978) |
| "D-Penicillamine treatment in rheumatoid arthritis resulted in a fall in plasma alfa-1-antitrypsin-IgA complexes which was significantly more pronounced among responders than among non-responders." | 3.66 | D-penicillamine treatment in rheumatoid arthritis monitored by plasma alfa-1-antitrypsin-IgA complexes and plasma and urinary sulphur containing aminoacids. ( Jeppsson, JO; Laurell, CB; Wollheim, FA, 1979) |
| "The effects of D-penicillamine on T-lymphocytes (rosette forming cells) and B-lymphocytes (surface IgG- and surface IgM-bearing cells) in peripheral blood of 13 patients with classical or definite rheumatoid arthritis were investigated at 4 weeks, 12 weeks and 24 weeks of treatment." | 3.66 | Effects of oral administration of D-penicillamine on T- and B-lymphocytes in peripheral blood of rheumatoid patients. ( Kosaka, S, 1979) |
| "Cytogenetic studies were performed on bone-marrow cells from 11 patients with rheumatoid arthritis treated with penicillamine." | 3.66 | Cytogenetic studies in patients treated with penicillamine. ( Ingeberg, S; Jensen, MK; Rasmussen, GG, 1979) |
| "Collagen biosynthesis was measured in skin biopsies taken from 13 patients with rheumatoid arthritis before and after at least 6 months' continuous treatment with D-penicillamine, 1." | 3.66 | Skin collagen biosynthesis in patients with rheumatoid arthritis treated with D-penicillamine. ( Francis, MJ; Loudon, M; Mowat, AG; Schorn, D, 1979) |
| "Penicillamine has been successfully reintroduced and continued for a minimum of 13 months in 5 patients who developed proteinuria during the first course of the drug." | 3.66 | Resumption of treatment with penicillamine after proteinuria. ( Davison, AM; Hill, A; Hill, H, 1979) |
| "There is much individual variation in the response of rheumatoid arthritis (RA) to penicillamine, some patients deriving benefit from very small doses." | 3.66 | Maintenance dose of penicillamine in rheumatoid arthritis: a comparison between a standard and a response-related flexible regimen. ( Brown, RM; Day, AT; Golding, JR; Hill, AG; Hill, HF; Lyle, WH, 1979) |
| "A woman with rheumatoid arthritis was treated with penicillamine and developed myasthenia gravis." | 3.66 | Penicillamine-induced myasthenia gravis associated with antibodies to acetylcholine receptor. ( Lindstrom, JM; Russell, AS, 1978) |
| "To assess toxicity of D-penicillamine a retrospective chart review was performed on 63 patients with rheumatoid arthritis receiving penicillamine." | 3.66 | Toxicity of D-penicillamine in rheumatoid arthritis. A report of 63 patients including two with aplastic anemia and one with the nephrotic syndrome. ( Kammerer, WH; Markenson, JA; Weiss, AS; Weiss, MS, 1978) |
| "The clinical and electrophysiological findings in 2 men who had developed a myasthenic syndrome after taking penicillamine for rheumatoid arthritis will be described." | 3.66 | [Myasthenic syndrome during penicillamine treatment (author's transl)]. ( Schumm, F; Stöhr, M, 1978) |
| "The effect of therapeutic concentrations of D-penicillamine, sodium aurothiomalate, and levamisole on in vitro neutrophil chemotaxis and random migration in normal subjects and patients with rheumatoid arthritis was studied." | 3.66 | Neutrophil chemotaxis in rheumatoid arthritis. Effect of D-penicillamine, gold salts, and levamisole. ( Mowat, AG, 1978) |
| "The taste function and the zinc and copper levels in serum and urine were followed for up tp 16 weeks in ten patients who were started on penicillamine therapy for generalized scleroderma (9 patients) and rheumatoid arthritis (one patient)." | 3.66 | Taste dysfunction and changes in zinc and copper metabolism during penicillamine therapy for generalized scleroderma. ( Knudsen, L; Weismann, K, 1978) |
| "Two patients with classical rheumatoid arthritis developed myopathy during treatment with penicillamine." | 3.66 | Penicillamine-induced polymyositis-dermatomyositis. ( Halberg, P; Højgaard, K; Lyon, BB; Petersen, J; Ullman, S, 1978) |
| "A 59-year-old woman has been treated for 5 months with penicillamine for a rheumatoid arthritis and developed a myasthenia syndrome with ptosis, diplopia, dysphagia and asthenia." | 3.66 | [Myasthenia syndrome after peroral treatment with penicillamine]. ( Francois, J; Gabriel, P; Verbraeken, H; Wille, C, 1978) |
| "Twenty patients with rheumatoid arthritis developing proteinuria when being treated with penicillamine have been studied." | 3.65 | Effect of penicillamine on the kidney. ( Davison, AM; Day, AT; Golding, JR; Thomson, D, 1977) |
| "In patients with rheumatoid arthritis neither indomethacin nor aspirin influenced the levels of the erythrocyte sedimentation rate (e." | 3.65 | A study of the influence of various antirheumatic drug regimens on serum acute-phase proteins, plasma tryptophan, and erythrocyte sedimentation rate in rheumatoid arthritis. ( Aylward, M; Maddock, J; Parker, RJ; Wheeldon, R, 1975) |
| "A patient with arthritis is described who developed a dermatitis herpetiformis-like rash after 8 months of D-penicillamine therapy and which cleared soon after the drug was discontinued." | 3.65 | Herpetiform pemphigus induced by penicillamine. ( Dawber, RP; Marsden, RA; Millard, PR; Mowat, AG, 1977) |
| "A case of dermatomyositis developing during the course of treatment with D-penicillamine in a patient with rheumatoid arthritis is described." | 3.65 | Dermatomyositis complicating penicillamine treatment. ( Fernandes, L; Hamilton, EB; Swinson, DR, 1977) |
| "Forty-four patients with definite or classic rheumatoid arthritis and failure to tolerate or respond to gold therapy were treated with D-penicillamine on a so-called go-slow, go-low regime." | 3.65 | D-penicillamine in the treatment of rheumatoid arthritis. ( Ford, DK; Patterson, CA; Robinson, HS; Stein, HB; Tsang, IK, 1977) |
| "Myasthenia gravis with thymic hyperplasia developed in a patient with Wilson's disease after eight years of penicillamine treatment." | 3.65 | Penicillamine-associated myasthenia gravis, antiacetylcholine receptor and antistriational antibodies. ( Dawkins, RL; Leedman, RJ; Masters, CL; Simpson, JA; Zilko, PJ, 1977) |
| "Four patients with rheumatoid arthritis developed heavy proteinuria after five to 12 months of treatment with D-penicillamine." | 3.65 | Immunopathology of penicillamine-induced glomerular disease. ( Dische, FE; Hamilton, EB; Parsons, V; Swinson, DR, 1976) |
| "This report concerns a 55-year-old woman who developed ocular myasthenia after 12 months treatment with D-Penicillamine for her rheumatoid arthritis." | 3.65 | [Ocular myasthenia caused by D-penicillamine (author's transl)]. ( Kommerell, G; Schmidt, D, 1976) |
| "A myasthenic reaction developed after an average latency of seven to eight months in 12 female patients (average age 51 years) treated with penicillamine for chronic rheumatoid arthritis." | 3.65 | [Penicillamine-induced myasthenia in chronic rheumatoid arthritis (author's transl)]. ( Hopf, HC; Janzen, RW; Meyer, W; Seitz, D, 1976) |
| "Fourteen patients who developed persistent proteinuria while on penicillamine for rheumatoid arthritis, were collected over a period of one year." | 3.65 | Penicillamine nephropathy in rheumatoid arthritis. A clinical, pathological and immunological study. ( Amer, B; Bacon, PA; Cumming, RH; Mackenzie, JC; Tribe, CR; Verrier-Jones, J, 1976) |
| "Thirteen patients, aged 27 to 70 years, with definite or classical rheumatoid arthritis were treated with penicillamine for six months." | 3.65 | Penicillamine in rheumatoid arthritis. Connective tissue changes and alterations in serum copper and phase reactants in relation to clinical improvement. ( Andreassen, T; Hansen, TM; Kofod, B; Lorenzen, IB; Manthorpe, R; Oxlund, H, 1976) |
| "In two patients with rheumatoid arthritis, immunoglobuline deposits in the skin were detected during D-penicillamine treatment." | 3.65 | [Autoimmune phenomena in D-penicillamine therapy]. ( Kolarz, G; Ludwig, H; Sabeti, M; Scherak, O, 1975) |
| "The sera of 40 patients with severe progressive rheumatoid arthritis were examined for the presence of soluble immune complexes before penicillamine therapy was started, and again after treatment for a mean period of 14-4 months." | 3.65 | Effect of penicillamine therapy on circulating immune complexes in rheumatoid arthritis. ( Ansell, BM; Barraclough, D; Holborow, EJ; Mohammed, I, 1975) |
| ") developed myasthenia gravis after taking penicillamine." | 3.65 | Myasthenia gravis associated with penicillamine treatment for rheumatoid arthritis. ( Bucknall, RC; Dixon A St, J; Glick, EN; Woodland, J; Zutshi, DW, 1975) |
| "In a 53-year-old woman an acute allergic thrombocytopenia (acute Werlhf's disease) occurred after treatment with D-penicillamine for one month which led to death." | 3.65 | [Severe side-effects of treatment with D-penicillamine (author's transl)]. ( Hennemann, HH; Hubertus, H; Stocker, WG, 1975) |
| "The authors present 5 cases of pemphigus induced by D-penicillamine in a series of 180 cases of rheumatoid arthritis treated with this medication." | 3.65 | [Pemphigus induced by D-penicillamine in rheumatoid arthritis. Study of 5 cases and systematic study of anti-intercellular substance antibodies of the skin in the course of treatment]. ( Benveniste, M; Camus, JP; Crouzet, J; Hewitt, J; Homberg, JC; Lessana, M, 1975) |
| "The report deals with 8 years of clinical experience with long-term application of D-penicillamine in rheumatoid arthritis." | 3.65 | [The effect of D-penicillamine on the course of chronic polyarthritis]. ( Miehlke, K, 1975) |
| " Chloroquine should mainly be administered in "lupoid" rheumatoid arthritis (R." | 3.65 | [Differential indications in rheumatism therapy on the basis of well-known drug side effects]. ( Mathies, H, 1975) |
| "The technetium index was measured in 22 patients with rheumatoid arthritis, before and after 6 months' treatment either with penicillamine or with anti-inflammatory drugs." | 3.65 | Objective measurement of rheumatoid arthritis using technetium index. ( Balme, HW; Huskisson, EC; Scott, J, 1976) |
| " Possible roles of the lysosomal collagenolytic enzyme system in experimental lathyrism in rats given penicillamine, and in erosion of cartilage in rheumatoid arthritis, are considered." | 3.65 | Effects of lysosomal collagenolytic enzymes, anti-inflammatory drugs and other substances on some properties of insoluble collagen. ( Anderson, AJ, 1969) |
| "Bucillamine was at least as effective ad D-penicillamine in terms of improvement in the swollen joint count, tenderness score, morning stiffness, modified health assessment questionnaire, and Westergren erythrocyte sedimentation rate (ESR), and more effective in terms of improvement in the tender joint count, grip strength, C-reactive protein (CRP), and rheumatoid factor (RF) titer." | 2.68 | A comparison between bucillamine and D-penicillamine in the treatment of rheumatoid arthritis. ( Kim, HA; Song, YW, 1997) |
| "To determine whether intermittent rather than daily administration of D-penicillamine (D-Pen) would effectively reduce the incidence of adverse effects without significantly diminishing the clinical benefits." | 2.67 | Intermittent treatment with D-penicillamine is effective in lower doses and with fewer adverse effects in patients with rheumatoid arthritis. ( Akahoshi, T; Hakoda, M; Kamatani, N; Kashiwazaki, S; Taniguchi, A, 1994) |
| "Least toxic was hydroxychloroquine (mean +/- SEM score 1." | 2.67 | The relative toxicity of disease-modifying antirheumatic drugs. ( Bloch, DA; Fries, JF; Ramey, D; Williams, CA, 1993) |
| "Nausea was the major side effect in the sulphasalazine treated group." | 2.65 | Comparison between penicillamine and sulphasalazine in rheumatoid arthritis: Leeds-Birmingham trial. ( Grindulis, KA; Hubball, S; McConkey, B; Neumann, VC; Wright, V, 1983) |
| "Captopril was therefore considered a potential slow-acting drug for treating rheumatoid arthritis." | 2.65 | Captopril: a new treatment for rheumatoid arthritis? ( Bird, HA; Dixon, JS; Martin, MF; McKenna, F; Surrall, KE; Wright, V, 1984) |
| "Osteoporosis is a common and important feature of rheumatoid disease which can be further influenced by the treatment administered." | 2.65 | Osteoporosis in the rheumatoid hand--the effects of treatment with D-penicillamine and oral gold salts. ( Schorn, D, 1983) |
| " The main task has been seen to be the exploration of various dosage schedules in the hope of finding an effective dose which does not produce a high incidence of adverse effect." | 2.65 | Penicillamine in rheumatoid arthritis. ( Hill, AG; Hill, HF, 1979) |
| "Rheumatoid arthritis is the autoimmune disorder most often associated with yellow nail syndrome." | 2.41 | Yellow nail syndrome associated with thiol compound therapy for rheumatoid arthritis. Two case reports. ( Despaux, J; Lehuédé, G; Michel, F; Toussirot, E; Wendling, D, 2002) |
| " DMARDs that combine efficacy with negligible renal adverse effects should be used for the treatment of patients susceptible to DMARD-associated renal damage." | 2.41 | Renal toxicity associated with disease-modifying antirheumatic drugs used for the treatment of rheumatoid arthritis. ( Schiff, MH; Whelton, A, 2000) |
| "That DMARDs are effective in treating rheumatoid arthritis is beyond question-just how effective they are and what combinations of DMARDs will show improved efficacy will provide data for the next annual review." | 2.40 | Disease-modifying antirheumatic drugs. ( Brooks, P; Conaghan, PG; Li, E, 1998) |
| " Open non-randomised uncontrolled studies have shown that antimalarials combined with cytotoxic agents are effective but highly toxic." | 2.39 | The use of antimalarials in combination with other disease modifying agents in RA--the British experience. ( Capell, HA; Duncan, MR, 1996) |
| "Rheumatoid arthritis is the commonest connective tissue disease associated with bronchiolitis obliterans, a clinico-pathologic entity of bronchiolar inflammation and fibrosis reflecting injury to the small airways, and presenting with symptoms and signs of small airways obstruction." | 2.38 | Bronchiolitis obliterans and rheumatoid arthritis. Report of a case in a Chinese patient on d-penicillamine and review of the literature. ( Wong, R; Yam, LY, 1993) |
| "Rheumatoid arthritis is associated with abnormalities in macrophage, lymphocyte, and fibroblast functions." | 2.38 | Pharmacology of antiarthritic drugs. ( Boyce, E, 1992) |
| "Rheumatoid arthritis is a severe disease and it is difficult to prevent the progression of disease." | 2.38 | [Gold compounds and D-penicillamine for therapy of rheumatoid arthritis]. ( Inoue, T; Miyamoto, S, 1992) |
| "Rheumatoid arthritis is a systemic disorder, but primarily involves chronic polyarticular inflammation." | 2.38 | Rheumatoid arthritis: current concepts and management, Part 2. ( Sterling, LP, 1990) |
| "Rheumatoid arthritis is a chronic inflammatory synovitis that primarily involves peripheral diarthrodial joints." | 2.37 | NIH conference. Rheumatoid arthritis: evolving concepts of pathogenesis and treatment. ( Decker, JL; Haraoui, B; Klippel, JH; Malone, DG; Schrieber, L; Steinberg, AD; Wahl, SM; Wilder, RL, 1984) |
| " Toxic influences effect thrombo- and leukocytopenia (incidence 5-15%), gastrointestinal disturbances (10-30%), changes or loss of taste (5-30%), loss of hair (1-2%), and partly proteinuria (5-20%)." | 2.37 | [D-penicillamine--side effects, pathogenesis and decreasing the risks]. ( Grasedyck, K, 1988) |
| "The severity of pulmonary fibrosis is not associated with rheumatologic symptoms or the duration of the associated RA, nor is there any clear relation to the extraarticular features of RA or serologic findings." | 2.37 | Pulmonary fibrosis in rheumatoid arthritis: a review of clinical features and therapy. ( Roschmann, RA; Rothenberg, RJ, 1987) |
| " Dosage by liquid phase chromatography enables study of intestinal absorption, reduced by meals, the distribution made according to a 2 compartment model, urinary and faecal excretion." | 2.36 | [Pharmacology and mechanism of action of D-penicillamine in rheumatoid polyarthritis]. ( Bisson, M; Clerc, D; Massias, P; Sallière, D, 1983) |
| "The cytotoxic agents used to treat rheumatoid arthritis, which likely have nonspecific anti-inflammatory actions and have serious long-term side effects, are also briefly reviewed." | 2.36 | Remission-inducing drugs in rheumatoid arthritis. ( Anastassiades, TP, 1980) |
| "Apart from the conventional treatment of the rheumatoid arthritis with steroidal and non-steroidal antirheumatic remedies, physiotherapy and balneotherapy as well as orthopaedic and surgical measures the basis therapy is an important factor." | 2.36 | [Basic therapy of rheumatoid arthritis]. ( , 1977) |
| "Treatment of rheumatoid arthritis is often frustrating for patient and physician alike because of its chronic nature and our lack of knowledge about precise cause." | 2.35 | Treatment of rheumatoid arthritis: a review including newer and experimental anti-inflammatory agents. ( Kaye, RL; Pemberton, RE, 1976) |
| "We describe three patients with minimal change nephrotic syndrome associated with penicillamine treatment." | 1.32 | [Minimal changes nephrotic syndrome associated to penicillamine treatment]. ( Basterrechea, MA; de Arriba, G; García-Martín, F; Giménez-Vega, E; Sánchez, J; Sánchez-Heras, M, 2004) |
| "To evaluate rates on the adverse side effect and discontinuation of second-line drugs frequently used in the treatment of rheumatoid arthritis (RA)." | 1.31 | [Retrospective study of adverse events in patients with rheumatoid arthritis treated with second-line drugs]. ( Jiang, L; Ni, L; Zhao, N, 2002) |
| "The renal biopsy showed minimal change glomerulopathy and no cellular infiltration in interstitial tissue by light microscopy and partial fusion of foot process by electron microscopy." | 1.31 | [A case of rheumatoid arthritis associated with minimal change nephrotic syndrome]. ( Hashimoto, K; Hosokawa, T; Matsubara, Y; Moriki, T; Nishimura, S; Nishiya, K; Ota, K; Tahara, K, 2001) |
| " There is no evidence that the dosage of drugs metabolized by the CYP3A4 isoenzyme needs to be adjusted for disease activity in RA." | 1.30 | Urinary 6 beta-hydroxycortisol excretion in rheumatoid arthritis. ( Beyeler, C; Bird, HA; Frey, BM, 1997) |
| "Renal biopsy showed focal segmental glomerulosclerosis (FSGS)." | 1.30 | [Focal segmental glomerulosclerosis presenting nephrotic syndrome and acute renal failure in a patient with rheumatoid arthritis]. ( Akikusa, B; Matsumura, R; Sueishi, M; Sugiyama, T; Tomioka, H, 1997) |
| "During the past few years the treatment of rheumatoid arthritis, the most frequent of the rheumatic inflammatory systemic diseases has improved a great deal." | 1.30 | [Rheumatoid arthritis. Conservative therapeutic possibilities today and in the future]. ( Aeschlimann, AG, 1998) |
| "Development of drug-induced systemic lupus erythematosus (SLE) is an uncommon complication of the use of D-penicillamine and sulphasalazine." | 1.29 | Combination therapy for rheumatoid arthritis and drug-induced systemic lupus erythematosus. ( Borg, AA; Davis, MJ; Dawes, PT; Shadforth, MF, 1994) |
| " Over a 2-yr period we have prospectively reviewed 114 patients with a suspected adverse cutaneous reaction to anti-rheumatic drugs." | 1.29 | Suspected cutaneous drug toxicity in rheumatoid arthritis--an evaluation. ( Davis, MJ; Dawes, PT; Mattey, DL; Smith, AG; Wilkinson, SM, 1993) |
| "BMT was used to treat severe aplastic anemia which was caused by gold in one case and D-penicillamine in the other." | 1.29 | Apparent cure of rheumatoid arthritis by bone marrow transplantation. ( Atkinson, K; Biggs, JC; Cohen, ML; Lowenthal, RM, 1993) |
| "Vasculitis was confirmed histologically in 96% of the subjects with RV." | 1.29 | Factors associated with the development of vasculitis in rheumatoid arthritis: results of a case-control study. ( Breedveld, FC; Hazes, JM; Vandenbroucke, JP; Voskuyl, AE; Westedt, ML; Zwinderman, AH, 1996) |
| "The long-term use of second-line antirheumatic drugs was prospectively studied in a consecutive sample of 245 patients with recently diagnosed rheumatoid arthritis." | 1.28 | Long-term second-line treatment: a prospective drug survival study. ( van de Putte, LB; van Leeuwen, MA; van Riel, PL; van Rijswijk, MH; van't Hof, MA; Wijnands, MJ, 1992) |
| "Rheumatoid arthritis is a chronic inflammatory disorder with considerable evidence of impaired regulation of the immune response, including defective suppressor cell function, especially in the synovial membrane." | 1.28 | Impaired suppressor cell activity due to surface sulphydryl oxidation in rheumatoid arthritis. ( Brown-Galatola, CH; Hall, ND, 1992) |
| "Rheumatoid nodules have been associated with a poor long-term prognosis." | 1.28 | Rheumatoid nodules do not predict response to treatment with slow-acting anti-rheumatic drugs. ( Hall, GM; Huskisson, EC; Scott, DL; Studnicke, A, 1991) |
| " Our findings explain a number of the toxic phenomena associated with D-penicillamine administration in RA." | 1.27 | D-Penicillamine induced toxicity in rheumatoid arthritis: the role of sulphoxidation status and HLA-DR3. ( Emery, P; Huston, G; Idle, JR; Mitchell, SC; Panayi, GS; Shah, RR; Smith, RL; Waring, RH; Welsh, KI, 1984) |
| "Active rheumatoid arthritis is associated with increased numbers of plaque forming cells in the peripheral blood, changes in the numbers of these cells providing an index of disease activity." | 1.27 | The influence of D-penicillamine therapy on numbers of circulating immunoglobulin secreting cells in rheumatoid arthritis. ( Corke, CF; Gul, V; Holborow, EJ; Huskisson, EC, 1984) |
| "Canine rheumatoid arthritis is an uncommon diagnosis, and it is not the intent of this discussion to encourage either the use of cytotoxic drugs or the experimentation with unproven agents in dogs with vaguely defined forms of arthritis." | 1.27 | Comparative therapeutics of canine and human rheumatoid arthritis. ( Romatowski, J, 1984) |
| "Rheumatoid arthritis is a very common disease with potentially serious disability in patients of all ages." | 1.27 | Rheumatoid arthritis. ( Dorwart, BB, 1984) |
| " Non-steroidal anti-inflammatory drugs in full dosage should always be the first choice of treatment." | 1.27 | Medical management of rheumatoid arthritis with emphasis on the Western Pacific Region. ( Muirden, KD, 1983) |
| "Rheumatoid arthritis is a disease of variable natural history." | 1.27 | Rheumatoid arthritis. ( Barraclough, D, 1983) |
| "Gold therapy has been continued in the presence of haematuria without ill effect." | 1.27 | Haematuria occurring during antirheumatoid therapy. ( Smith, DH; White, EG; Zaphiropoulos, GC, 1984) |
| "Penicillamine disulfides have been analysed by automatic amino acid analysis." | 1.27 | Methods for assaying D-penicillamine in a clinical setting. ( Crawhall, JC, 1984) |
| "While rheumatoid arthritis is characteristically an indolent disease, failure to recognize its urgent complications can cause significant morbidity and mortality." | 1.27 | Emergencies in rheumatoid arthritis. ( Weiner, SR, 1984) |
| "Rheumatoid arthritis is a disorder that frequently can be controlled with a program of physical therapy, rest and therapeutic doses of aspirin or another nonsteroidal anti-inflammatory medication." | 1.27 | Slow-acting anti-rheumatic drug therapy for rheumatoid arthritis. ( Clegg, DO; Ward, JR, 1987) |
| "Numerous drugs are available for the treatment of rheumatoid arthritis." | 1.27 | Rheumatoid arthritis: a pharmacologic overview. ( Pinals, RS, 1988) |
| " Adverse effects occurred more frequently after rapid increases in dosage." | 1.27 | The toxicity of D-penicillamine in systemic sclerosis. ( Blair, S; Medsger, TA; Steen, VD, 1986) |
| "The majority of patients were being treated for rheumatoid arthritis." | 1.27 | European League against Rheumatism study of adverse reactions to D-penicillamine. ( Kay, A, 1986) |
| " During gradual reduction of the steroid dosage osteocalcin returned to pretreatment values." | 1.27 | Serum osteocalcin in rheumatoid arthritis and other inflammatory arthritides: relation between inflammatory activity and the effect of glucocorticoids and remission inducing drugs. ( Ekenstam, EA; Hällgren, R; Ljunghall, S, 1986) |
| "Rheumatoid arthritis is a chronic lifelong disease, facts which must be considered when concepts of therapy are developed." | 1.27 | [The concept of basic therapy of chronic polyarthritis with D-penicillamine: clinical experiences over 10 years]. ( Hohmeister, R, 1988) |
| "Purpura was found to be associated with age, sex, disease duration, and amount of disability." | 1.27 | Postmarketing surveillance in rheumatology: analysis of purpura and upper abdominal pain. ( Bloch, DA; Fries, JF; Lane, NE; Segal, MR; Spitz, PW; Williams, C, 1988) |
| "The pathogenesis of rheumatoid arthritis is unknown, but clear abnormalities of the immune system are well documented in this disease." | 1.26 | Determination of T lymphocyte subpopulations by monoclonal antibodies in rheumatoid arthritis. Influence of immunomodulating agents. ( Goldstein, G; Hermanns, P; Kung, P; Schindler, J; Van Wauwe, J; Veys, EM, 1981) |
| "Levamisole has been shown to be an effective, penicillamine-like drug." | 1.26 | Treatment of rheumatoid arthritis with levamisole. ( Huskisson, EC, 1980) |
| "Rats bred for resistance to the dextran anaphylactoid reaction exhibit contact sensitivity to oxazolone even better than rats which respond to clinical dextran." | 1.26 | Effects of levamisole and D-penicillamine on contact sensitivity to oxazolone in rats. ( West, GB, 1982) |
| " An overestimation of rare side-effects of drugs should not block the application of certain medicaments, however, they should be given only in such a high dosage as it is necessary." | 1.26 | [Hematotoxic lesions caused by non-steroidal antirheumatic agents]. ( Hüge, W; Stobbe, H, 1980) |
| "Levamisole is a welcome addition to the list of penicillamine-like drugs." | 1.26 | The place of levamisole in the armamentarium for rheumatoid arthritis. ( Huskisson, EC, 1978) |
| " The cells show a diminished sensitivity to D-Pen added after 24 hours in culture, although the dose-response relationship is maintained." | 1.26 | The inhibitory effect of D-penicillamine on human lymphocyte cultures stimulated by phytohaemagglutinin, the antagonistic action of L-cysteine and synergistic inhibition by copper sulphate. ( Maini, RN; Roffe, L; Room, G, 1979) |
| " Its indications in the therapy of RA were defined, and current principles of dosage were presented." | 1.26 | Penicillamine in rheumatoid arthritis: clinical pharmacology and biochemical properties. ( Jaffe, IA, 1979) |
| "A comparison of two series of patients with rhe,matic polyarthritis, the one (n = 140) treated with dosage equal to or higher than 900 mg, the other (n = 60) with dosage between 600 and 750 mg, did not reveal significant difference in clinical and biological efficacy." | 1.26 | [Study of optimal posology of penicillamine in the treatment of common rheumatoid polyarthritis (apropos of a personal series of 200 cases)]. ( Camus, JP; Crouzet, J; Leca, AP; Prier, A, 1977) |
| "A retrospective study of penicillamine toxicity in 156 patients yielded a high incidence of toxic reaction (62%), necessitating discontinuation of the drug therapy in 36% of the patients." | 1.26 | Toxicity of penicillamine. A serious limitation to therapy in rheumatoid arthritis. ( Bernhard, GC; Goldman, AL; Halverson, PB; Kozin, F, 1978) |
| "The drugs mainly used for basical treatment of rheumatoid arthritis are cytostatics, D-penicillamine, gold salts and chloroquine." | 1.26 | [On the mode of action of antirheumatic drugs (author's transl)]. ( Müller, AE; Thiele, HG, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1040 (81.06) | 18.7374 |
| 1990's | 203 (15.82) | 18.2507 |
| 2000's | 34 (2.65) | 29.6817 |
| 2010's | 5 (0.39) | 24.3611 |
| 2020's | 1 (0.08) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Y | 1 |
| Qiu, Y | 1 |
| Chen, M | 1 |
| Jiang, Y | 1 |
| Qiu, X | 1 |
| Gao, L | 1 |
| Desai, RJ | 1 |
| Solomon, DH | 1 |
| Schneeweiss, S | 1 |
| Danaei, G | 1 |
| Liao, KP | 1 |
| Kim, SC | 1 |
| Palazzi, C | 1 |
| D'Angelo, S | 1 |
| Olivieri, I | 1 |
| Yukawa, N | 1 |
| Mimori, T | 1 |
| Valachová, K | 1 |
| Rapta, P | 1 |
| Kogan, G | 1 |
| Hrabárová, E | 1 |
| Gemeiner, P | 1 |
| Soltés, L | 1 |
| Daoussis, D | 1 |
| Panoulas, VF | 1 |
| John, H | 1 |
| Toms, TE | 1 |
| Antonopoulos, I | 1 |
| Treharne, G | 1 |
| Nightingale, P | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Uncontrolled Study to Evaluate Efficacy of Tocilizumab in Patients With Moderate or Severe Rheumatoid Arthritis and Candidates With a Biological Monotherapy[NCT02087696] | Phase 4 | 122 participants (Anticipated) | Interventional | 2014-05-31 | Recruiting | ||
| The Efficacy of Ultrasound Guided Posterior Sacroiliac Ligament Corticosteroid Injection in Pregnancy-Related Pelvic Girdle Pain: A Randomized Controlled Trial[NCT02044991] | Phase 2 | 2 participants (Actual) | Interventional | 2013-10-24 | Terminated (stopped due to The study was halted prematurely due to poor recruitment) | ||
| Singlet Oxygen Quantification After Skin Exposure to Ultraviolet A (UVA) Light[NCT05865431] | 17 participants (Actual) | Interventional | 2017-03-17 | Completed | |||
| The Effects of Manual Therapy Applied to the Cervical Region on Balance and Proprioception in Patients With Nonspesific Neck Pain: A Randomised Placebo Controlled Study[NCT04794647] | 66 participants (Actual) | Interventional | 2020-01-02 | Completed | |||
| Effectiveness of Cyanoacrylate Glue in the Fixation of Midline and Peripherally Inserted Central Catheters in Hospitalized Adult Patients: Randomised Clinical Trial (CIANO-ETI)[NCT05299060] | 216 participants (Actual) | Interventional | 2020-09-16 | Completed | |||
| Safety, Activity, and Pharmacology of Nivolumab in Patients With Advanced Non-Small Cell Lung Cancer and Pre-existing Autoimmune Disease[NCT03656627] | Phase 1 | 7 participants (Actual) | Interventional | 2019-06-27 | Terminated (stopped due to low accrual) | ||
| Clinically Important Changes in Rheumatoid Arthritis[NCT00056602] | 192 participants (Actual) | Observational | 2003-03-18 | Completed | |||
| Evolution of Clinical State of Patients With Rheumatic Disease on Lower Limbs or Rachis, 6 Months After Spa Treatment[NCT03336099] | 120 participants (Actual) | Interventional | 2016-03-29 | Completed | |||
| BotulInum Toxin Type A for Peripheral Neuropathic Pain in subjEcts With Carpal Tunnel Syndrome: a Multicenter, Randomized, Doubleblind, Placebo-controlled Study[NCT05411900] | Phase 2 | 164 participants (Anticipated) | Interventional | 2022-05-25 | Recruiting | ||
| The Effect Of The Wireless Fetal Monitoring Used During Birth On The Women's Comfort, Labour Pain And Birth Satisfaction[NCT05778435] | 88 participants (Actual) | Interventional | 2021-09-11 | Completed | |||
| A Randomized Placebo Controlled Trial Testing The Effect of Zoledronic Acid on Hip Osteoarthritis[NCT04303026] | Phase 3 | 70 participants (Anticipated) | Interventional | 2020-03-02 | Recruiting | ||
| Radiofrequency Ablation of the Medial Branch Nerve as a Novel Treatment for Posterior Element Pain From Vertebral Compression Fractures[NCT03651804] | Phase 4 | 60 participants (Anticipated) | Interventional | 2019-04-10 | Suspended (stopped due to Difficulty recruiting members) | ||
| Tolerability, Safety and Activity of IDN5243, 4 mg Bid Intramuscularly in the Treatment of Low Back Pain. A Prospective, Open Label, Single-center, Uncontrolled Study[NCT02568826] | Phase 2 | 0 participants (Actual) | Interventional | 2016-04-30 | Withdrawn (stopped due to No patients enrolled in the study.) | ||
| Professor, School of Nursing, China Medical University Hospital, Principal Investigator[NCT04595253] | 200 participants (Anticipated) | Interventional | 2020-09-20 | Recruiting | |||
| Evaluation of the Effectiveness of a Phlebology-oriented Spa Treatment on the Quality of Life of Patients Suffering From Chronic Venous Insufficiency of the Lower Limbs, 6-month After the Spa Treatment[NCT05449743] | 100 participants (Anticipated) | Interventional | 2022-07-11 | Recruiting | |||
| Clinical Efficacy in Relieving Dentin Hypersensitivity of Nanohydroxyapatite-Containing Toothpastes and Cream[NCT02918617] | Phase 2 | 203 participants (Actual) | Interventional | 2015-05-31 | Completed | ||
| Comparison of Oral Gabapentin and Pregabalin in Postoperative Pain Control After Photorefractive Keratectomy: a Prospective, Randomized Study.[NCT00954187] | 8 participants (Actual) | Interventional | 2009-11-30 | Terminated (stopped due to PI left institution) | |||
| Effects of Smartphone Usage Duration on Neck Dysfunction in Young Versus Middle Aged Patients With Chronic Mechanical Neck Pain[NCT03745469] | 80 participants (Actual) | Observational | 2018-11-20 | Completed | |||
| Evaluation of Pain and Anxiety in Patients With an Invasive Procedure in Emergencies: Randomized Trial[NCT03641859] | 71 participants (Actual) | Interventional | 2018-08-23 | Completed | |||
| Randomized Controlled Trial Comparing the Effectiveness of Two Post-fasciectomy Rehabilitation Protocols Differing in Intensity and Implementation of Modalities in Patients With Dupuytren's Disease[NCT03982719] | 40 participants (Anticipated) | Interventional | 2019-06-30 | Enrolling by invitation | |||
| Hand Rehabilitation With Music Therapy Technique (Sonification) and Leap Motion Controller in Stroke Patients[NCT03306797] | 65 participants (Actual) | Interventional | 2017-03-28 | Completed | |||
| "Development and Validation of New SNU Illustrated Pain Rating Scale for Effective Assessment of Acute Postoperative Pain: a Comparative Study With Numeric Rating Scale"[NCT03764046] | 100 participants (Anticipated) | Observational | 2019-01-01 | Not yet recruiting | |||
| Clinical Evolution of Patients Suffering From Lower Limb Rheumatological Conditions 6 Months After Spa Treatment[NCT03538470] | 150 participants (Anticipated) | Interventional | 2018-06-01 | Active, not recruiting | |||
| Physical Therapist as Primary Assessor for Patients With Knee Pain in Primary Health Care. A Randomized Controlled Study[NCT03715764] | 69 participants (Actual) | Interventional | 2013-04-01 | Completed | |||
| Virtual Reality Intervention on Anxiety and Pain Among Adult Patients Ubdergoing an Awake Minor Suture: A Pilot Randomized Controlled Trial[NCT05796076] | 80 participants (Anticipated) | Interventional | 2023-02-03 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Pain is measured using the Pain Numeric Rating Scale (NRS), which ranges from 0 to 10 with higher scores indicating greater pain. This measure is recorded at baseline (0 weeks) and 8 weeks. The change in pain between these two time points (i.e., the difference score) is compared between the two groups. (NCT02044991)
Timeframe: 8 weeks
| Intervention | change score on the NRS pain scale (Median) |
|---|---|
| Treatment | -3 |
Disability is measured at baseline (0 weeks) and week 8 using the Oswestry Disability Index (ODI), which is a measure of low back pain that ranges from 0 points to 100 with higher scores indicating greater disability. The change in disability between these two time points (i.e., the difference score) is compared between the two groups. (NCT02044991)
Timeframe: 8 weeks
| Intervention | change score on the ODI scale (Median) |
|---|---|
| Treatment | -15.25 |
Pelvic functioning is measured at baseline (0 weeks) and week 8 using the Pelvic Girdle Questionnaire (PGQ), which ranges from 0 to 100 points with higher scores revealing greater pelvic girdle pain. The change in pelvic functioning between these two time points (i.e., the difference score) is compared between the two groups. (NCT02044991)
Timeframe: 8 weeks
| Intervention | change score on the PGQ scale (Median) |
|---|---|
| Treatment | -35.5 |
Patient's response to an air stimulus is recorded on a Dental Pain Scale (none[1]-mild[2]-moderate[3]-severe[4]). (NCT02918617)
Timeframe: Baseline to 8 weeks
| Intervention | percentage change from baseline (Mean) |
|---|---|
| Control Toothpaste Containing Novamin® Technology | -35.14 |
| Control Toothpaste Containing 1500 Ppm Fluoride as MFP | -43.35 |
| Test Toothpaste With Nano-HAP (High Concentration) | -34.15 |
| Test Toothpaste With Nano-HAP (Low Concentration) | -38.63 |
| Test Toothpaste With Nano-HAP and Potassium Nitrate (KNO3) | -43.95 |
| Control Toothpaste Without Nano-HAP | -33.63 |
| Test Toothpaste With Nano-HAP (Medium Concentration) | -49.35 |
| Test Cream With Nano-HAP (Higher Concentration) | -17.47 |
| Control Cream Without Nano-HAP | -28.54 |
Patient's response to an cold stimulus is recorded on a Dental Pain Scale (none[1]-mild[2]-moderate[3]-severe[4]). (NCT02918617)
Timeframe: Baseline to 8 weeks
| Intervention | percentage change from baseline (Mean) |
|---|---|
| Control Toothpaste Containing Novamin® Technology | -35.37 |
| Control Toothpaste Containing 1500 Ppm Fluoride as MFP | -30.18 |
| Test Toothpaste With Nano-HAP (High Concentration) | -39.81 |
| Test Toothpaste With Nano-HAP (Low Concentration) | -38.41 |
| Test Toothpaste With Nano-HAP and Potassium Nitrate (KNO3) | -35.03 |
| Control Toothpaste Without Nano-HAP | -34.07 |
| Test Toothpaste With Nano-HAP (Medium Concentration) | -46.21 |
| Test Cream With Nano-HAP (Higher Concentration) | -15.30 |
| Control Cream Without Nano-HAP | -25.57 |
Patient's response to an air stimulus is recorded on a Visual Analog Scale of 0-100 with 0 representing no pain and 100 representing the worst possible pain. (NCT02918617)
Timeframe: Baseline to 8 weeks
| Intervention | percentage change from baseline (Mean) |
|---|---|
| Control Toothpaste Containing Novamin® Technology | -51.44 |
| Control Toothpaste Containing 1500 Ppm Fluoride as MFP | -51.59 |
| Test Toothpaste With Nano-HAP (High Concentration) | -41.59 |
| Test Toothpaste With Nano-HAP (Low Concentration) | -38.64 |
| Test Toothpaste With Nano-HAP and Potassium Nitrate (KNO3) | -53.16 |
| Control Toothpaste Without Nano-HAP | -47.19 |
| Test Toothpaste With Nano-HAP (Medium Concentration) | -56.85 |
| Test Cream With Nano-HAP (Higher Concentration) | -38.99 |
| Control Cream Without Nano-HAP | -50.67 |
Patient's response to cold stimulus is recorded on a Visual Analog Scale of 0-100 with 0 signifying no pain and 100 signifying the worst possible pain (NCT02918617)
Timeframe: Baseline to 8 weeks
| Intervention | percentage change from baseline (Mean) |
|---|---|
| Control Toothpaste Containing Novamin® Technology | -48.14 |
| Control Toothpaste Containing 1500 Ppm Fluoride as MFP | -34.96 |
| Test Toothpaste With Nano-HAP (High Concentration) | -44.71 |
| Test Toothpaste With Nano-HAP (Low Concentration) | -31.95 |
| Test Toothpaste With Nano-HAP and Potassium Nitrate (KNO3) | -42.49 |
| Control Toothpaste Without Nano-HAP | -35.67 |
| Test Toothpaste With Nano-HAP (Medium Concentration) | -48.80 |
| Test Cream With Nano-HAP (Higher Concentration) | -34.90 |
| Control Cream Without Nano-HAP | -39.36 |
A Swedish version of Euroqol-5 dimensions-3 levels (EQ5D-3L) will be used to assess perceived self-rated health-related quality of life. The questionnaire contain five dimensions and results in an index ranging from -0,549 to 1 using the UK tariffs. An index of 1 indicate full health. (NCT03715764)
Timeframe: 12 months
| Intervention | score on a scale (Mean) |
|---|---|
| Physical Therapy Assessment | 0.804 |
| Physician Assessment | 0.825 |
A Swedish version of Euroqol-5 dimensions-3 levels (EQ5D-3L) will be used to assess perceived self-rated health-related quality of life. The EQ5D-VAS is a visual analogue scale ranging from 0 to 100, where 0 is worst imaginable health state and 100 is best imaginable health state. (NCT03715764)
Timeframe: 12 months
| Intervention | score on a scale (Mean) |
|---|---|
| Physical Therapy Assessment | 81 |
| Physician Assessment | 77 |
The mean pain intensity (over the past month) will be measured by a visual analogue scale (VAS) ranged from 0 which will correspond no pain and 100 the worst imagined pain. (NCT03715764)
Timeframe: 12 months
| Intervention | units on a scale (Mean) |
|---|---|
| Physical Therapy Assessment | 21.79 |
| Physician Assessment | 23.29 |
Physical performance will be measured with 30 seconds chair stand test (30CST). Number of chair stands will be counted. (NCT03715764)
Timeframe: 12 months
| Intervention | stands (Mean) |
|---|---|
| Physical Therapy Assessment | 15 |
| Physician Assessment | 15 |
145 reviews available for penicillamine and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Hepatitis C virus-related arthritis.
Topics: Adrenal Cortex Hormones; Ankle; Antibodies, Viral; Arthralgia; Arthritis, Infectious; Arthritis, Rhe | 2008 |
[Effect of disease modifying anti-rheumatic drugs on radiographic progression in rheumatoid arthritis].
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cyclosporine; Cysteine; Disease Progression; Drug Thera | 2009 |
Perioperative management of the patient with rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Aspirin; Cervical Vertebrae; | 2010 |
Pulmonary manifestations of rheumatoid arthritis.
Topics: Abatacept; Anti-Inflammatory Agents; Antimetabolites; Arthritis, Rheumatoid; Gold; Humans; Immunocon | 2010 |
Yellow nail syndrome associated with thiol compound therapy for rheumatoid arthritis. Two case reports.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Nail Diseases; Penicillamine; Tio | 2002 |
[Combination therapy of disease-modifying antirheumatic drugs(DMARDs) in rheumatoid arthritis].
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Auranofin; Clinical Trials as Topic; Drug Therapy, Comb | 2002 |
[Kidney involvement in rheumatoid arthritis].
Topics: Amyloidosis; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; A | 2003 |
Rheumatoid arthritis.
Topics: Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Rheumatoid; Auranofin; Azathioprine; Cyclop | 2003 |
NIH conference. Rheumatoid arthritis: evolving concepts of pathogenesis and treatment.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Chloroquine; Gluc | 1984 |
The role of copper in inflammatory disorders.
Topics: Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Arthritis, Rheumatoid; Copper; Humans; Penicil | 1984 |
Do drugs change the course of rheumatoid arthritis?
Topics: Arthritis, Rheumatoid; Azathioprine; Blood Sedimentation; C-Reactive Protein; Chloroquine; Cyclophos | 1980 |
Prostaglandins and inflammation.
Topics: Animals; Anti-Inflammatory Agents; Antibody Formation; Arthritis, Rheumatoid; Blood Coagulation; Bon | 1980 |
[D(-)penicillamine: pharmacology and clinical uses].
Topics: Arthritis, Rheumatoid; Hepatolenticular Degeneration; Humans; Huntington Disease; Lead Poisoning; Li | 1982 |
Rheumatoid arthritis: some personal considerations on treatment. Part II.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Bed Rest; Drug Interactions; D | 1983 |
[Main anti-rheumatoidal drugs--the place of levamisole among them].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Delayed-Action Preparations; Drug Evaluation; Gluco | 1983 |
[Pharmacology and mechanism of action of D-penicillamine in rheumatoid polyarthritis].
Topics: Arthritis, Rheumatoid; Cartilage; Chemotaxis, Leukocyte; Glutathione; Humans; Immunity; Intestinal A | 1983 |
Does drug therapy slow radiographic deterioration in rheumatoid arthritis?
Topics: Antimalarials; Arthritis, Rheumatoid; Arthrography; Azathioprine; Clinical Trials as Topic; Cyclopho | 1983 |
Remission-inducing therapy in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Chronic Disease; Clinical Trials as | 1983 |
Rheumatoid arthritis: relationship with HLA-D.
Topics: Adult; Arthritis, Juvenile; Arthritis, Rheumatoid; Child; Diabetes Mellitus, Type 1; Felty Syndrome; | 1983 |
Problems of antiarthritic therapy in the elderly.
Topics: Adrenal Cortex Hormones; Age Factors; Aged; Allopurinol; Anti-Inflammatory Agents; Anti-Inflammatory | 1984 |
[Rheumatoid arthritis. Considerations on a rational therapeutic strategy].
Topics: Adjuvants, Immunologic; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antimalar | 1984 |
The pharmacology of antirheumatic drugs.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Azathioprine; Chloroquine; Cyclophosphamide; Glucoc | 1984 |
Remittive therapy in rheumatoid arthritis: clinical uses and mechanisms of action.
Topics: Antimalarials; Arthritis, Rheumatoid; Biomechanical Phenomena; Gold; Humans; Penicillamine; Terminol | 1984 |
Combined disease-modifying chemotherapy for intractable rheumatoid arthritis.
Topics: Adult; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chlorambucil; Clinical Trials as Topic; Drug | 1984 |
Controlled, double-blind, comparative studies of disease modifying anti-rheumatic drugs in the treatment of patients with rheumatoid arthritis. A review.
Topics: Adolescent; Adult; Arthritis, Rheumatoid; Azathioprine; Chloroquine; Clinical Trials as Topic; Cyclo | 1984 |
Immunosuppressive actions of gold salts.
Topics: Anti-Inflammatory Agents; Antibody Formation; Arthritis, Rheumatoid; Aurothioglucose; B-Lymphocytes; | 1983 |
Is gold necessary in so called chrysotherapy?
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Carbon Radioisotopes; Clinical Trials as T | 1983 |
The role of therapeutic plasmapheresis in the rheumatic diseases.
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Gold; Humans; Immune Complex Diseases; Lupus Erythe | 1981 |
Therapeutic progress--review VI. Treatment of rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Gold; Humans; Penicillamine; Prostaglandins; Radiog | 1982 |
Disease-modifying drugs for progressive rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Aurothioglucose; Azathioprine; Chloroquine; Cyclophosphamide; Gold; Gold Sodi | 1980 |
Remission-inducing drugs in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Chloroquine; Gold Sodium Thiomalate; Humans; Kinetics; Levamisole; Penicillam | 1980 |
[Anti-inflammatory or antirheumatic agents? Pharmacological activity and therapeutic effectiveness of non-steroid anti-inflammatory drugs: comparative study. III].
Topics: Adjuvants, Immunologic; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Autoimmune Diseases; Chloro | 1980 |
Recent developments in disease-modifying antirheumatic drugs.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chloroquine; Gold; Humans; Immunosuppressive Agents | 1980 |
[Which anti-inflammatory agents should be used in rheumatology?].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Anticoagulants; Arthritis, Rheumatoid; Drug Syner | 1981 |
Biochemical parameters in the assessment of anti-inflammatory drugs--a review.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Blood Proteins; Blood Sedim | 1980 |
Anti-rheumatic drugs: present deadlock and new vistas.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Copper; Fatty Acids, Essential; Female; Fr | 1980 |
Induction of auto-immune syndromes by penicillamine therapy in rheumatoid arthritis and other diseases.
Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Captopril; Cystinuria; Hepatolenticular Degeneration; Hu | 1981 |
How do second-line agents work?
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cyclophosphamide; Cyclosporine; Gold; Humans; Penicilla | 1995 |
Disease-modifying antirheumatic drugs, including methotrexate, gold, antimalarials, and D-penicillamine.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Antirheumatic Agents; Arthritis, Rheumatoid; | 1995 |
Approach to the patient with rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Female; Humans; Immunosuppressive Ag | 1994 |
Disease-modifying antirheumatic drugs, including methotrexate, sulfasalazine, gold, antimalarials, and penicillamine.
Topics: Age Factors; Antimalarials; Arthritis, Rheumatoid; Clinical Trials as Topic; Cysteine; Digestive Sys | 1994 |
[Renal damage in rheumatoid arthritis].
Topics: Adult; Amyloidosis; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cyclosporine; Fe | 1994 |
Fatal cholestatic hepatitis caused by D-penicillamine.
Topics: Adult; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Cholestasis; Fatal Outcome; Fe | 1994 |
Second line (disease modifying) treatment in rheumatoid arthritis: which drug for which patient?
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Auranofin; Blood Sedimentation; | 1993 |
Optimizing combination chemotherapy for rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Azathioprine; Cyclosporine; Drug Therapy, Combination; Humans; Methotrexate; | 1993 |
Bronchiolitis obliterans and rheumatoid arthritis. Report of a case in a Chinese patient on d-penicillamine and review of the literature.
Topics: Adult; Arthritis, Rheumatoid; Biopsy; Bronchiolitis Obliterans; Bronchoscopy; China; Female; Hong Ko | 1993 |
Slow-acting antirheumatic drugs. Drug interactions of clinical significance.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Drug Interactions; Gold; Humans; Hydroxychloroquine; Pe | 1995 |
Coexistent membranous nephropathy and ANCA-positive crescentic glomerulonephritis in association with penicillamine.
Topics: Antibodies, Antineutrophil Cytoplasmic; Antirheumatic Agents; Arthritis, Rheumatoid; Autoantibodies; | 1996 |
A cost effectiveness analysis of cyclosporine in rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Cost-Benefit Analysis; Cyclosporine; Huma | 1996 |
The use of antimalarials in combination with other disease modifying agents in RA--the British experience.
Topics: Antimalarials; Antineoplastic Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Clinical Trials a | 1996 |
Penicillamine.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Humans; Penicillamine | 1997 |
Disease-modifying antirheumatic drugs.
Topics: Antimalarials; Antirheumatic Agents; Arthritis, Rheumatoid; Drug Therapy, Combination; Gold; Humans; | 1997 |
[Combined administration of long-acting antirheumatic drugs in the treatment of chronic polyarthritis].
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Clinical Trials as Topic; Cyclosporins; D | 1997 |
Disease-modifying antirheumatic drugs.
Topics: Antimalarials; Antirheumatic Agents; Arthritis, Rheumatoid; Drug Therapy, Combination; Humans; Liver | 1998 |
[Combination therapy of rheumatoid arthritis].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Antirheumatic Agents; Arthritis, Rheumatoid; | 1998 |
Sulfasalazine treatment for rheumatoid arthritis: a metaanalysis of 15 randomized trials.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Female; Gold Sodium Thiomalate; Humans; Hydroxychloroqu | 1999 |
Penicillamine for rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Humans; Penicillamine | 2000 |
DMARDs in the treatment of rheumatoid arthritis: current agents and future developments.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Antirheumatic Agents; Arthritis, Rheumatoid; | 2000 |
Penicillamine for treating rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Controlled Clinical Trials as Topic; Humans; Penicillam | 2000 |
Renal toxicity associated with disease-modifying antirheumatic drugs used for the treatment of rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cyclosporine; Humans; Kidney; Organogold Compounds; Pen | 2000 |
Progress in the treatment of rheumatoid arthritis.
Topics: Analgesics; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Cyclo | 2001 |
The mechanism of action of antirheumatic agents.
Topics: Acetylglucosaminidase; Adjuvants, Immunologic; Anti-Inflammatory Agents; Antineoplastic Agents; Arth | 1979 |
[Rheumatology in 1975-1976].
Topics: Adult; Aged; Arthritis, Rheumatoid; Bismuth; Chondrocalcinosis; Crohn Disease; Female; Histocompatib | 1977 |
Drug treatment of rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Analgesics; Antimalarials; Arthritis, Rheumatoid; Aspirin; Aurothioglucose; | 1978 |
Penicillamine and wound healing in rheumatoid arthritis.
Topics: Arthritis, Juvenile; Arthritis, Rheumatoid; Humans; Penicillamine; Wound Healing | 1977 |
Is the mechanism of action during treatment of rheumatoid arthritis with penicillamine and gold thiomalate the same?
Topics: Arthritis, Rheumatoid; Drug Therapy, Combination; Gold Sodium Thiomalate; Humans; Penicillamine; Pro | 1977 |
[Penicillamine: its use in rheumatoid arthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Drug Eruptions; Drug Evaluation; Female; Fever; Gastrointestinal | 1979 |
Penicillamine in rheumatoid arthritis: adverse effects.
Topics: Anemia, Aplastic; Anti-Glomerular Basement Membrane Disease; Arthritis, Rheumatoid; Bone Marrow; Dru | 1979 |
[Spontaneous septic arthritides during rheumatoid arthritis].
Topics: Adrenal Cortex Hormones; Arthritis, Infectious; Arthritis, Rheumatoid; Gold; Humans; Immunity, Cellu | 1977 |
[Possibilities of drug therapy in monoarticular and oligoarticular diseases].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Arthritis; Arthritis | 1979 |
[Basic therapy of rheumatoid arthritis].
Topics: Alkylating Agents; Antimalarials; Antimetabolites, Antineoplastic; Antineoplastic Agents; Arthritis, | 1977 |
Update: treatment of rheumatic disease.
Topics: Allopurinol; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Gold; Gout; Humans; Lupus Erythematosu | 1978 |
Drug therapy and circulating immune complexes in rheumatoid arthritis.
Topics: Antigen-Antibody Complex; Arthritis, Rheumatoid; Complement System Proteins; Cyclophosphamide; Felty | 1978 |
D-penicillamine in the treatment of rheumatoid arthritis and progressive systemic sclerosis.
Topics: Animals; Arthritis, Rheumatoid; Chelating Agents; Collagen; Copper; Humans; Leukopenia; Nephrotic Sy | 1976 |
Treatment of rheumatoid arthritis: a review including newer and experimental anti-inflammatory agents.
Topics: Activities of Daily Living; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antimalarials; Arthri | 1976 |
Rheumatology.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Child; Gold; HLA Antigens; Humans; J | 1976 |
Treatment of rheumatoid arthritis. New thoughts on the classic pyramid approach.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antimala | 1992 |
Pharmacology of antiarthritic drugs.
Topics: Adrenal Cortex Hormones; Antimalarials; Arthritis, Rheumatoid; Aurothioglucose; Azathioprine; Cyclop | 1992 |
Current concepts in the management of rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Aged; Antibiotics, Antineoplastic; Antirheumatic Agents; Arthritis, Rheumat | 1992 |
[Dermatopolymyositis induced by D-penicillamine in rheumatoid polyarthritis. Apropos of 1 case with review of the literature].
Topics: Arthritis, Rheumatoid; Dermatomyositis; Female; Humans; Middle Aged; Penicillamine | 1992 |
The case for early intervention in rheumatoid arthritis.
Topics: Antimalarials; Arthritis, Rheumatoid; Female; Gold; Humans; Male; Morbidity; Penicillamine; Survival | 1992 |
[Gold compounds and D-penicillamine for therapy of rheumatoid arthritis].
Topics: Arthritis, Rheumatoid; Auranofin; Gold Sodium Thiomalate; Humans; Penicillamine | 1992 |
[Neuromuscular complications of D-penicillamine in rheumatoid arthritis].
Topics: Aged; Arthritis, Rheumatoid; Female; Graves Disease; Humans; Male; Middle Aged; Myasthenia Gravis; M | 1992 |
Disease-modifying antirheumatic drugs: gold, penicillamine, antimalarials, and sulfasalazine.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Antirheumatic Agents; Arthritis, Rheumatoid; | 1991 |
[Current status of drug therapy in chronic polyarthritis].
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Chloroquin | 1991 |
Rethinking the therapeutic pyramid for rheumatoid arthritis. When are NSAIDs alone not enough?
Topics: Arthritis, Rheumatoid; Gold; Humans; Immunosuppressive Agents; Penicillamine; Prednisone | 1992 |
Therapy for rheumatoid arthritis: combinations of disease-modifying drugs and new paradigms of treatment.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Azathiopri | 1991 |
"Yellow nail syndrome" and rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Female; Humans; Male; Midd | 1991 |
Combination chemotherapy in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Drug Therapy, Combination; Gold; Humans; Hydroxychloroquine; Penicillamine | 1991 |
[D-penicillamine induced myasthenia gravis in a patient with rheumatoid arthritis].
Topics: Arthritis, Rheumatoid; Female; Humans; Middle Aged; Myasthenia Gravis; Penicillamine | 1991 |
The use of combinations of disease-modifying antirheumatic agents in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Arthritis, Rheumatoid; Clinical Trials as To | 1990 |
Care of the person with rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Humans; Methot | 1990 |
Disease-modifying antirheumatic drugs: gold, penicillamine, antimalarials, and sulfasalazine.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Arthritis, Rheumatoid; Gold; Humans; Penicil | 1990 |
Rheumatoid arthritis: current concepts and management, Part 2.
Topics: Adult; Anti-Inflammatory Agents; Antimalarials; Antirheumatic Agents; Arthritis, Rheumatoid; Female; | 1990 |
The comparative efficacy and toxicity of second-line drugs in rheumatoid arthritis. Results of two metaanalyses.
Topics: Antimalarials; Arthritis, Rheumatoid; Auranofin; Gold; Humans; Meta-Analysis as Topic; Methotrexate; | 1990 |
[Pleuropulmonary manifestations of rheumatoid arthritis].
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Bronchial Diseases; Bronchoalveolar Lavage Fluid; Cyclo | 1990 |
Combination therapy of rheumatoid arthritis--rationale and overview.
Topics: Antimalarials; Antineoplastic Agents; Arthritis, Rheumatoid; Gold; Humans; Injections, Intramuscular | 1990 |
Combination therapy in rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Azathioprin | 1990 |
[Anti-radical enzymes, oxygenated free radicals and lipoperoxydation in rheumatoid polyarthritis. Effects of treatment with D-penicillamine].
Topics: Arthritis, Rheumatoid; Catalase; Free Radicals; Glutathione Peroxidase; Humans; Lipid Peroxidation; | 1990 |
[A case report of rheumatoid arthritis which showed acute renal failure, nephrotic syndrome and drug-related lupus-like syndrome caused by D-penicillamine].
Topics: Acute Kidney Injury; Aged; Arthritis, Rheumatoid; Humans; Lupus Erythematosus, Systemic; Male; Nephr | 1990 |
D-penicillamine.
Topics: Arthritis, Juvenile; Arthritis, Rheumatoid; Drug Prescriptions; Humans; Penicillamine; Rheumatic Dis | 1990 |
D-penicillamine induced pemphigus treated with methylprednisolone pulse therapy.
Topics: Aged; Arthritis, Rheumatoid; Female; Humans; Methylprednisolone; Pemphigus; Penicillamine | 1990 |
Penicillamine-induced pemphigus erythematosus.
Topics: Administration, Cutaneous; Arthritis, Rheumatoid; Betamethasone; Fluorescent Antibody Technique; Hum | 1990 |
Disease-modifying agents in rheumatoid arthritis.
Topics: Acute-Phase Proteins; Antimalarials; Arthritis, Rheumatoid; Aurothioglucose; Depression, Chemical; G | 1987 |
Rheumatoid arthritis therapy: the slow-acting agents.
Topics: Age Factors; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Arthr | 1989 |
Radiologic assessment as an outcome measure in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Carpal Bones; Clinical Trials as Topic; Humans; Met | 1989 |
A rheumatological dilemma: is it possible to modify the course of rheumatoid arthritis? Can we answer the question?
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Auranofin; Aurothioglucose; Azathioprine; Clinical | 1985 |
The use of chloroquine and D-penicillamine in the treatment of rheumatoid arthritis.
Topics: Anti-Glomerular Basement Membrane Disease; Arthritis, Rheumatoid; Captopril; Chloroquine; Clinical T | 1986 |
D-penicillamine: chemistry and clinical use in rheumatic disease.
Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Drug Eruptions; Gold Sodium Thiomalate; Hematologic Dise | 1986 |
[Side effects of d-penicillamine in the treatment of rheumatoid arthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Autoimmune Diseases; Drug Eruptions; Female; Hematologic Disease | 1986 |
Synthesis of rheumatoid factor in vitro: implications for the pathogenesis of rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; B-Lymphocytes; Gold Sodium Thiomalate; Hemolytic Pl | 1985 |
[D-penicillamine--a current review of areas of use and dosage guidelines].
Topics: Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Penic | 1988 |
[D-penicillamine--side effects, pathogenesis and decreasing the risks].
Topics: Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Humans; Penicillamine; Risk Factors | 1988 |
[Current aspects of D-penicillamine and pregnancy].
Topics: Abnormalities, Drug-Induced; Arthritis, Rheumatoid; Cystinuria; Female; Hepatolenticular Degeneratio | 1988 |
Drug-induced autoimmune disease.
Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Gold; HLA Antigens; Humans; Hydralazine; Lupus Erythemat | 1987 |
Pharmacology of auranofin: overview and update.
Topics: Administration, Oral; Animals; Arthritis, Rheumatoid; Auranofin; Gold; Gold Sodium Thiomalate; Human | 1986 |
[Auranofin and aurothiomalate sodium: a comparative review (and II) Efficacy, tolerance and safety].
Topics: Anemia; Arthritis, Rheumatoid; Auranofin; Aurothioglucose; Clinical Trials as Topic; Diarrhea; Drug | 1985 |
Rheumatoid arthritis: can the long-term outcome be altered?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Glucocorticoids; Gold; Humans; Hydro | 1988 |
Can 'disease modifying' drugs influence outcome in rheumatoid arthritis?
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Cyclophosphamide; Follow-U | 1988 |
Current concepts in clinical therapeutics: disease-modifying drugs for rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Arthritis, Rheumato | 1987 |
Management of rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Azathioprine; Chloroquine; Cyc | 1986 |
Current concepts in the treatment of rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; As | 1986 |
Therapeutic approaches to the treatment of rheumatoid disease.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Azathioprin | 1986 |
[Penicillamine in 1985].
Topics: Adolescent; Adult; Aged; Arthritis, Juvenile; Arthritis, Rheumatoid; Child; Drug Tolerance; Female; | 1986 |
[D-penicillamine and collagen].
Topics: Aminopropionitrile; Arthritis, Rheumatoid; Autoantibodies; Bronchi; Cicatrix; Collagen; Collagen Dis | 1986 |
Pulmonary fibrosis in rheumatoid arthritis: a review of clinical features and therapy.
Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents; Arthritis, Rheumatoid; Azathioprine; Fe | 1987 |
Penicillamine induced pemphigus.
Topics: Aged; Arthritis, Rheumatoid; Female; Fluorescent Antibody Technique; Humans; Male; Middle Aged; Pemp | 1985 |
Joint damage in rheumatoid arthritis: radiological assessments and the effects of anti-rheumatic drugs.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Arthrography; Clinical Trials as Topic; Gold; Human | 1985 |
[Management strategy of chronic polyarthritis].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Azathioprin | 1985 |
Short term efficacy of methotrexate in the treatment of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Double-Blin | 1985 |
Longterm methotrexate therapy in rheumatoid arthritis: a review.
Topics: Arthritis, Rheumatoid; Biopsy; Chemical and Drug Induced Liver Injury; Drug Resistance; Gold; Humans | 1985 |
Lupus-like syndromes induced by drugs.
Topics: Antibodies, Antinuclear; Antibody Formation; Arthritis, Rheumatoid; Chlorpromazine; DNA, Single-Stra | 1974 |
[Treatment of rheumatoid arthritis using D-penicillamine].
Topics: Adult; Agranulocytosis; Arthritis, Rheumatoid; Biodegradation, Environmental; Female; Humans; Kidney | 1974 |
[Drug and physical therapy of primary chronic polyarthritis].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Antineoplastic Agents; Arthritis, Rheumatoid; | 1972 |
Immunosuppressive drugs in rheumatoid arthritis.
Topics: Adrenocorticotropic Hormone; Aminopterin; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Autoimmun | 1971 |
The antivitamin B 6 effect of penicillamine: clinical and immunological implications.
Topics: Antibody Formation; Arthritis, Rheumatoid; Drug Antagonism; Drug Interactions; Humans; Immunosuppres | 1972 |
[Therapeutic use of d-penicillamine].
Topics: Arthritis, Rheumatoid; Basement Membrane; Collagen; Copper; Cystinuria; Hematopoiesis; Hepatolenticu | 1972 |
Advances in the treatment of rheumatic diseases.
Topics: Acetaminophen; Alkylating Agents; Anti-Inflammatory Agents; Antimetabolites; Arthritis, Rheumatoid; | 1973 |
[Chronic polyarthritis. Changes--surgical and conservative treatment].
Topics: Adult; Antibody Formation; Antigen-Antibody Complex; Antineoplastic Agents; Arthritis, Juvenile; Art | 1974 |
Hyperviscosity syndromes associated with immunoglobulin abnormalities.
Topics: Animals; Arthritis, Rheumatoid; Blood Protein Disorders; Blood Viscosity; Cardiovascular Diseases; E | 1973 |
Copper and taste sensitivity.
Topics: Arthritis, Rheumatoid; Ceruloplasmin; Copper; Cystinuria; Depression, Chemical; Hepatolenticular Deg | 1968 |
[Considerations on the role of copper in rheumatoid arthritis].
Topics: Arthritis, Rheumatoid; Copper; Female; Humans; Jaundice; Liver; Male; Penicillamine | 1969 |
Immunosuppressive therapy in severe rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Azathioprine; Chlorambucil; Cyclophosphamide; Female; Humans; Immunosuppressi | 1971 |
[Current possibilities in the antiphlogistic and immunosuppressive therapy of progressive chronic polyarthritis].
Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Arthritis, Rheumatoid; Chronic Disease; Glucocortic | 1971 |
[Penicillamine in the light of current clinical research].
Topics: Antidotes; Arthritis; Arthritis, Rheumatoid; Chronic Disease; Collagen; Copper; Depression, Chemical | 1970 |
152 trials available for penicillamine and Arthritis, Rheumatoid
| Article | Year |
|---|---|
The development and evaluation of a drug information leaflet for patients with rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Child; Chil | 2003 |
Criteria for improvement in rheumatoid arthritis: alternatives to the American College of Rheumatology 20.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Double-Blind Method; | 2004 |
Comparison between penicillamine and sulphasalazine in rheumatoid arthritis: Leeds-Birmingham trial.
Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Sedimentation; C-Reactive Protein; Clinical Trials as Topi | 1983 |
Long-term study of management of rheumatoid arthritis.
Topics: Acute Disease; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Bed Rest; Clinical Trials as Topic; | 1984 |
Captopril: a new treatment for rheumatoid arthritis?
Topics: Adult; Aged; Arthritis, Rheumatoid; Captopril; Clinical Trials as Topic; Double-Blind Method; Female | 1984 |
Gold vs D-penicillamine double blind study and followup.
Topics: Adult; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Drug Eruptions; Female; | 1984 |
Low-dose D-penicillamine therapy in rheumatoid arthritis. A controlled, double-blind clinical trial.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Dose-Response Relationship | 1983 |
[Pyrithioxin in the treatment of patients with rheumatoid arthritis (comparative study with D-penicillamine)].
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Humans; Penicillamine; Pyridines; Pyrithiox | 1983 |
Does drug therapy slow radiographic deterioration in rheumatoid arthritis?
Topics: Antimalarials; Arthritis, Rheumatoid; Arthrography; Azathioprine; Clinical Trials as Topic; Cyclopho | 1983 |
Remission-inducing therapy in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Chronic Disease; Clinical Trials as | 1983 |
Radiographic evaluation of the course of articular disease.
Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Clinical Trials as Topic; Cyclophosphamide; Gold; Hu | 1983 |
Rheumatoid arthritis: disease-modifying antirheumatic drugs.
Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Clinical Trials as Topic; Gold; Humans; Penicillamin | 1983 |
Antimalarial drugs for rheumatoid arthritis.
Topics: Amodiaquine; Antimalarials; Arthritis, Rheumatoid; Body Weight; Chloroquine; Clinical Trials as Topi | 1983 |
Controlled trial of hydroxychloroquine and D-penicillamine singly and in combination in the treatment of rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combinati | 1984 |
D-penicillamine withdrawal in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; C-Reactive Protein; Clinical Trials as Topic; Drug Administration Schedule; F | 1984 |
Azathioprine versus D-penicillamine in rheumatoid arthritis patients who have been treated unsuccessfully with gold.
Topics: Arthritis, Rheumatoid; Azathioprine; Clinical Trials as Topic; Double-Blind Method; Female; Gold; Hu | 1984 |
Combined disease-modifying chemotherapy for intractable rheumatoid arthritis.
Topics: Adult; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chlorambucil; Clinical Trials as Topic; Drug | 1984 |
Controlled, double-blind, comparative studies of disease modifying anti-rheumatic drugs in the treatment of patients with rheumatoid arthritis. A review.
Topics: Adolescent; Adult; Arthritis, Rheumatoid; Azathioprine; Chloroquine; Clinical Trials as Topic; Cyclo | 1984 |
Double-blind trial of levamisole, penicillamine and azathioprine in rheumatoid arthritis. Clinical, biochemical, radiological and scintigraphic studies.
Topics: Adult; Aged; Arthritis, Rheumatoid; Azathioprine; Clinical Trials as Topic; Female; Humans; Levamiso | 1984 |
Osteoporosis in the rheumatoid hand--the effects of treatment with D-penicillamine and oral gold salts.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Auranofin; Aurothioglucose; Female; Gold; Humans; M | 1983 |
A 12-month comparative trial of auranofin and D-penicillamine in rheumatoid arthritis.
Topics: Adult; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Auranofin; Aurothioglucose; Clinical Trials | 1983 |
Is gold necessary in so called chrysotherapy?
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Carbon Radioisotopes; Clinical Trials as T | 1983 |
Auranofin and D-penicillamine: a one year comparative study of safety and efficacy in patients with rheumatoid arthritis followed by a two year open assessment of auranofin.
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Auranofin; Aurothioglucose; Female; Fo | 1984 |
[Treatment of patients with rheumatoid arthritis with DMARD (disease modifying anti-rheumatic drugs)].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Azathioprine; Chloroquine; Clinical Trials as Topic | 1984 |
The role of therapeutic plasmapheresis in the rheumatic diseases.
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Gold; Humans; Immune Complex Diseases; Lupus Erythe | 1981 |
[Comparative study of the efficacy of 2 different doses of D-penicillamine in rheumatoid arthritis].
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Drug Eruptions; Female; Humans | 1981 |
A comparison of low dose levamisole and penicillamine in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Female; Humans; Levamisole; Male; Middle Ag | 1983 |
Low-dose penicillamine treatment of RA. Comparison of 600 mg and 300 mg regimens.
Topics: Adult; Arthritis, Rheumatoid; Blood Sedimentation; Clinical Trials as Topic; Dose-Response Relations | 1982 |
Does the order of second-line treatment in rheumatoid arthritis matter?
Topics: Adult; Aged; Arthritis, Rheumatoid; Drug Administration Schedule; Female; Gold Sodium Thiomalate; Hu | 1982 |
5-Thiopyridoxine in rheumatoid arthritis: clinical and experimental studies.
Topics: Animals; Arthritis; Arthritis, Rheumatoid; Clinical Trials as Topic; Copper; Humans; Kynurenine; Mal | 1980 |
Varied regimens in RA and pseudogout evaluated.
Topics: Aged; Arthritis, Rheumatoid; Chondrocalcinosis; Clinical Trials as Topic; Colchicine; Drug Therapy, | 1980 |
[Role of immunologic indicators in clinico-laboratory findings in the planning of therapeutic regimen and evaluation of its effectiveness in rheumatoid arthritis].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Cyclophosphamide; Drug Ad | 1980 |
Antirheumatic activity of fenclofenac.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Humans; Middle Aged; Penic | 1980 |
[Clinical trial in couples of effectiveness and side-effects of gold and D-penicillamine in long term treatment of rheumatoid arthritis (author's transl)].
Topics: Adult; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Gold; Humans; Male; Middle Aged; Pen | 1980 |
Evaluation of disease activity in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Blood Sedimentation; Clinical Trials as Topic; Gold; Humans; Penicillamine | 1980 |
Effectiveness of levamisole in rheumatoid arthritis: Immune changes and long-term results.
Topics: Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Female; Humans; I | 1981 |
Biochemical parameters in the assessment of anti-inflammatory drugs--a review.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Blood Proteins; Blood Sedim | 1980 |
[Effect of cuprenil (D-penicillamine) treatment on the clinical course of rheumatoid arthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Follow-Up Studies; Humans; Mal | 1981 |
Clinical trial of penicillamine in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Humans; Male; Medical Records; | 1981 |
Thymopoietin in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Sedimentation; Clinical Trials as Topic; Humans; Levamisol | 1982 |
Endpoint measures in rheumatoid arthritis clinical trials: group summary and individual patient analysis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Data Interpretation, Statistical; Disability Evaluation | 1994 |
Intermittent treatment with D-penicillamine is effective in lower doses and with fewer adverse effects in patients with rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Data Interpretation, Statistical; Drug Administration Schedule; Drug T | 1994 |
Effect of D-penicillamine on lymphocyte subsets: correlation with clinical response in rheumatoid arthritis.
Topics: Adolescent; Adult; Arthritis, Rheumatoid; Female; Follow-Up Studies; Humans; Lymphocyte Subsets; Mal | 1994 |
Outcome of second line therapy in rheumatoid arthritis.
Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Humans; Middle Aged; Or | 1994 |
Bronchoalveolar lavage and lung biopsy in rheumatoid arthritis. In vivo effects of disease modifying antirheumatic drugs.
Topics: Aged; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Biopsy; Bronchoalveolar | 1993 |
[A comparative controlled trial of 2 administration modalities of tiopronin in rheumatoid arthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Ceruloplasmin; Copper; Dose-Response Relationship, Drug; Drug Ev | 1993 |
The relative toxicity of disease-modifying antirheumatic drugs.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Azathiopri | 1993 |
[A long-term clinical analysis of the rheumatoid patients treated by a combination of GST and CCA].
Topics: Activities of Daily Living; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirh | 1995 |
[Microalbuminuria in rheumatoid arthritis].
Topics: Adult; Aged; Albuminuria; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Male; Middle | 1996 |
Thyroid function and immune profile in rheumatoid arthritis. A controlled study.
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Monitoring, Immunologic; Oste | 1996 |
A comparison between bucillamine and D-penicillamine in the treatment of rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, R | 1997 |
Intention-to-treat analysis of 200 patients with rheumatoid arthritis 12 years after random allocation to either sulfasalazine or penicillamine.
Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Follow-Up Studi | 1998 |
A long-term five-year randomized controlled trial of hydroxychloroquine, sodium aurothiomalate, auranofin and penicillamine in the treatment of patients with rheumatoid arthritis.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Auranofin; Female; Gold Sodium Thiomalate; | 1998 |
[Efficacy of D-penicillamine and methotrexate in the treatment of rheumatoid arthritis in relation to levels of circulating rheumatoid factors of different classes].
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Biomarkers; Drug Therapy, Combination; Fem | 1999 |
Aggressive treatment in early rheumatoid arthritis: a randomised controlled trial. On behalf of the Rheumatic Research Foundation Utrecht, The Netherlands.
Topics: Adult; Aged; Analysis of Variance; Antirheumatic Agents; Arthritis, Rheumatoid; Auranofin; Aurothiog | 2000 |
Effect of patient education on adherence to drug treatment for rheumatoid arthritis: a randomised controlled trial.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Biomarkers; Blood Viscosity; C-Reactive Pr | 2001 |
Long-term effects of alclofenac.
Topics: Animals; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Humans; Indomethacin; Penicillami | 1976 |
Alclofenac and D-penicillamine. Comparative trial in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Drug Eruptions; Female; Humans; Male; Middle Aged; | 1978 |
Immunostimulant therapy with levamisole for rheumatoid arthritis.
Topics: Animals; Arthritis, Rheumatoid; Cell Migration Inhibition; Clinical Trials as Topic; Complement Syst | 1976 |
Comparison of penicillamine and gold treatment in early rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Clinical Trials as Topic; Drug Evaluation; Female; Gold Sodium Thiomal | 1978 |
Serum sulfhydryl levels in rheumatoid patients treated with gold thiomalate and penicillamine.
Topics: Adult; Arthritis, Rheumatoid; Blood Sedimentation; Gold Sodium Thiomalate; Humans; Middle Aged; Peni | 1978 |
The influence of alclofenac treatment on acute-phase proteins, plasma tryptophan, and erythrocyte sedimentation rate in patients with rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Blood Proteins; Blood Sedimentation; C-Reactive Protein; Clinical Trials as T | 1975 |
[Penicillamine (dimethylcysteine, DISTA) in rheumatoid arthritis].
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Drug Evaluation; Humans; Penicillamine | 1977 |
[Review of 36 cases of rheumatoid arthritis treated with penicillamine D].
Topics: Adult; Arthritis, Rheumatoid; Capsules; Clinical Trials as Topic; Drug Evaluation; Female; Humans; M | 1977 |
Treatment of rheumatoid arthritis with penicillamine.
Topics: Arthritis, Rheumatoid; Azathioprine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Dru | 1977 |
[Clinical evaluation of D-penicillamine for the treatment of rheumatoid arthritis by a double blind test].
Topics: Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Male; | 1977 |
[Cellular immunity in rheumatoid arthritis. Effect of therapy].
Topics: Antimalarials; Arthritis, Rheumatoid; B-Lymphocytes; Clinical Trials as Topic; Fluorescent Antibody | 1977 |
[The action of D-penicillamine on the distribution of T and B-lymphocytes in rheumatoid arthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; B-Lymphocytes; Clinical Trials as Topic; Complement Fixation Tes | 1977 |
[3 years of penicillamine D therapy of 100 patients with rheumatoid polyarthritis].
Topics: Adult; Arthritis, Rheumatoid; Clinical Trials as Topic; Drug Evaluation; Humans; Middle Aged; Penici | 1977 |
[D-penicillamine in the treatment of rheumatoid arthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Pen | 1977 |
[A trial of comparative effects of gold salts and D-penicillamine in rheumatoid arthritis].
Topics: Adult; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Gold; Humans; Male; Middle Aged; Pen | 1978 |
Penicillamine for rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Humans; Penicillamine; Pl | 1978 |
International symposium on levamisole in rheumatoid arthritis. A review of short and longterm effects on articular manifestations.
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Humans; Joints; Levamisole; Mo | 1978 |
A review of the effects of levamisole on erythrocyte sedimentation rate, acute phase proteins, and anemia.
Topics: alpha 1-Antitrypsin; Arthritis, Rheumatoid; Blood Proteins; Blood Sedimentation; C-Reactive Protein; | 1978 |
Therapy of rheumatoid disease.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Clinical Tr | 1979 |
The use of penicillamine in the treatment of rheumatoid arthritis and scleroderma.
Topics: Adult; Arthritis, Rheumatoid; Child; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; | 1979 |
A controlled trial of penicillamine in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Pen | 1979 |
To assess the effect of slow-acting anti-rheumatic drugs in man.
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Humans; Penicillamine | 1979 |
Penicillamine in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Drug Administration Schedule; Humans; Penicillamine | 1979 |
Synthetic D(-)penicillamine in rheumatoid arthritis. Double-blind controlled study of a high and low dosage regimen.
Topics: Acetaminophen; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Dyspepsia; Female; Humans; | 1975 |
Azathioprine and penicillamine in treatment of rheumatoid arthritis: a controlled trial.
Topics: Adult; Aged; Arthritis, Rheumatoid; Azathioprine; Blood Sedimentation; Clinical Trials as Topic; Fem | 1976 |
[D-penicillamine in the treatment of rheumatoid polyarthritis].
Topics: Adult; Arthritis, Rheumatoid; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Male; Middl | 1976 |
Controlled trial of D-penicillamine in rheumatoid arthritis. Dose effect and the role of zinc.
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Female; | 1976 |
Trial comparing azathioprine and penicillamine in treatment of rheumatoid arthritis [proceedings].
Topics: Arthritis, Rheumatoid; Azathioprine; Clinical Trials as Topic; Humans; Penicillamine | 1976 |
[Long term treatment of rheumatoid arthritis. Experiences with D-penicillamine in comparison with gold and immunosuppressive drugs (author's transl)].
Topics: Adolescent; Adult; Arthritis, Rheumatoid; Blood Sedimentation; Clinical Trials as Topic; Female; Gol | 1975 |
Evidence that D-penicillamine alters the course of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Gold Sodium Thiomalate; Humans; Male; Penic | 1976 |
Letter: Gold therapy in 1975.
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Gold; Humans; Immunosuppressive Agents; Penicillami | 1975 |
[Results with D-penicillamine in the treatment of rheumatoid arthritis].
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Drug Evaluation; Humans; Penicillamine | 1975 |
Toxicity profiles of disease modifying antirheumatic drugs in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; | 1991 |
[A comparative evaluation of parenteral and oral preparations of gold and D-penicillamine in the treatment of rheumatoid nephropathy].
Topics: Administration, Oral; Antirheumatic Agents; Arthritis, Rheumatoid; Auranofin; Dimercaprol; Drug Ther | 1991 |
Comparison of cyclosporine and D-penicillamine for rheumatoid arthritis: a randomized, double blind, multicenter study.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Cyclosporins; Dose-Response Relationship, Drug; Doub | 1991 |
The use of combinations of disease-modifying antirheumatic agents in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Arthritis, Rheumatoid; Clinical Trials as To | 1990 |
Degree and extent of response to sulphasalazine or penicillamine therapy for rheumatoid arthritis: results from a routine clinical environment over a two-year period.
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administrati | 1990 |
The comparative efficacy and toxicity of second-line drugs in rheumatoid arthritis. Results of two metaanalyses.
Topics: Antimalarials; Arthritis, Rheumatoid; Auranofin; Gold; Humans; Meta-Analysis as Topic; Methotrexate; | 1990 |
A study of adjunctive copper sulphate treatment in patients with rheumatoid arthritis who have relapsed while taking D-penicillamine.
Topics: Adult; Aged; Arthritis, Rheumatoid; Copper; Copper Sulfate; Double-Blind Method; Drug Therapy, Combi | 1991 |
Longterm cyclosporine therapy in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Creatinine; Cyclosporins; Double-Blind Method; Female; Glomerula | 1991 |
Analysis of improvement in individual rheumatoid arthritis patients treated with disease-modifying antirheumatic drugs, based on the findings in patients treated with placebo. The Cooperative Systematic Studies of Rheumatic Diseases Group.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Auranofin; Azathioprine; Double-Blind Method; Drug | 1990 |
Second-line antirheumatic drugs in the elderly with rheumatoid arthritis: a post hoc analysis of three controlled trials.
Topics: Administration, Oral; Aged; Arthritis, Rheumatoid; Auranofin; Azathioprine; Double-Blind Method; Dru | 1990 |
Reversible nephrotoxicity of cyclosporine in rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Creatinine; Cyclosporin | 1990 |
Radiological progression in rheumatoid arthritis: do D-penicillamine and hydroxychloroquine have different effects?
Topics: Arthritis, Rheumatoid; C-Reactive Protein; Clinical Trials as Topic; Female; Foot; Hand; Humans; Hyd | 1990 |
Double blind placebo controlled trial of pulse treatment with methylprednisolone combined with disease modifying drugs in rheumatoid arthritis.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Azathioprine; Double-Blind Method; Drug Admin | 1990 |
OM-8980 and D-penicillamine in the treatment of rheumatoid arthritis. A 12-month double-blind randomized study.
Topics: Adjuvants, Immunologic; Adult; Aged; Analysis of Variance; Antigens, Bacterial; Arthritis, Rheumatoi | 1990 |
Acute phase proteins and clinical synovitis activity in patients with rheumatoid arthritis.
Topics: Acute-Phase Proteins; Arthritis, Rheumatoid; Azathioprine; Blood Sedimentation; Hemoglobinometry; Hu | 1987 |
Which traditional measures should be used in rheumatoid arthritis clinical trials?
Topics: Administration, Oral; Arthritis, Rheumatoid; Auranofin; Clinical Trials as Topic; Factor Analysis, S | 1989 |
Long-term (four year) clinical trial with tenoxicam and basis therapy in patients suffering from rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Bli | 1989 |
Sulphasalazine versus penicillamine in the treatment of rheumatoid arthritis.
Topics: Acetyltransferases; Arthritis, Rheumatoid; Arthrography; Clinical Trials as Topic; Female; Humans; M | 1989 |
Radiologic assessment as an outcome measure in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Carpal Bones; Clinical Trials as Topic; Humans; Met | 1989 |
Pharmacokinetic interactions of penicillamine in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Chloroquine; Clinical Trials as Topic; Drug Interactions; Female | 1989 |
A rheumatological dilemma: is it possible to modify the course of rheumatoid arthritis? Can we answer the question?
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Auranofin; Aurothioglucose; Azathioprine; Clinical | 1985 |
Does sulphasalazine cause folate deficiency in rheumatoid arthritis?
Topics: Arthritis, Rheumatoid; Erythrocyte Indices; Folic Acid Deficiency; Humans; Penicillamine; Sulfasalaz | 1985 |
Combination therapy with pulsed methylprednisolone in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Drug Combinations; Female; Humans; Infusions, Parenteral; Male; Methylprednis | 1985 |
The use of chloroquine and D-penicillamine in the treatment of rheumatoid arthritis.
Topics: Anti-Glomerular Basement Membrane Disease; Arthritis, Rheumatoid; Captopril; Chloroquine; Clinical T | 1986 |
A prospective five-year comparison of treatment which included penicillamine with that excluding penicillamine in early rheumatoid arthritis. The Multicentre Trial Group.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Drug Therapy, Combination; | 1986 |
[New basic preparations with prolonged action in the treatment of rheumatoid arthritis].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Clinical Trials as Topic; Hum | 1987 |
Combination therapy in rheumatoid arthritis--study design.
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Penicillamine; S | 1987 |
Effects of sulphasalazine on faecal flora in patients with rheumatoid arthritis: a comparison with penicillamine.
Topics: Arthritis, Rheumatoid; Bacteria; Clostridium perfringens; Escherichia coli; Feces; Humans; Middle Ag | 1987 |
SA 96 (N-(2-mercapto-2-methylpropanoyl)-L-cysteine) in rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury | 1986 |
Toxicity of longterm low dose D-penicillamine therapy in rheumatoid arthritis. Cooperative Systematic Studies of Rheumatic Disease Group.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Drug | 1987 |
Short course of synacthen therapy as an adjunct in the management of rheumatoid arthritis.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Arthritis, Rheumatoid; Aurothioglucose; Blood Sedimentatio | 1985 |
Scintimetric assessment of synovitis activity during treatment with disease modifying antirheumatic drugs.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Azathioprine; Clinical | 1988 |
Auranofin versus penicillamine in rheumatoid arthritis. One-year results from a prospective clinical investigation.
Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Auranofin; | 1986 |
Auranofin or D-penicillamine in the treatment of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Auranofin; Aurothioglucose; Clinical Trials as Topic; Double-Blind Method; Fe | 1986 |
[Long-term comparative studies on gold, D-penicillamine, and NSAIDs for the treatment of early rheumatoid arthritis. 1. Evaluation of one year's treatment].
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Gold Sodium Thiomalate; Humans; Indomethacin; Penic | 1986 |
Hematuria in patients with rheumatoid arthritis receiving gold and D-penicillamine.
Topics: Adult; Aged; Arthritis, Rheumatoid; Auranofin; Clinical Trials as Topic; Double-Blind Method; Female | 1987 |
[Auranofin and aurothiomalate sodium: a comparative review (and II) Efficacy, tolerance and safety].
Topics: Anemia; Arthritis, Rheumatoid; Auranofin; Aurothioglucose; Clinical Trials as Topic; Diarrhea; Drug | 1985 |
Combination of methylprednisolone pulse therapy and remission inducing drugs in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Azathioprine; Clinical Trials as Topic; Double-Blind Method; Dru | 1987 |
Combined D-penicillamine and chloroquine treatment of rheumatoid arthritis--a comparative study.
Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Sedimentation; C-Reactive Protein; Chloroquine; Clinical T | 1987 |
Lack of induction of antinuclear antibodies by D-penicillamine in rheumatoid arthritis: a controlled study.
Topics: Antibodies, Antinuclear; Arthritis, Rheumatoid; Double-Blind Method; Humans; Lupus Erythematosus, Sy | 1986 |
Prediction of progressive joint damage in patients with rheumatoid arthritis receiving gold or D-penicillamine therapy.
Topics: Arthritis, Rheumatoid; Aspartate Aminotransferases; Clinical Trials as Topic; Female; Gold; Humans; | 1986 |
General practitioner assistance with gold and penicillamine therapy of rheumatoid arthritis--a four year prospective study.
Topics: Arthritis, Rheumatoid; Follow-Up Studies; Gold; Humans; Penicillamine; Random Allocation | 1987 |
Rheumatoid arthritis: supplemental L-cysteine in penicillamine treatment--a controlled study.
Topics: Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Cysteine; Female; Humans; Male; Middle | 1985 |
Joint damage in rheumatoid arthritis: radiological assessments and the effects of anti-rheumatic drugs.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Arthrography; Clinical Trials as Topic; Gold; Human | 1985 |
[Chlorbutin, azathioprine, D-penicillamine and levamisole (decaris) in the treatment of patients with rheumatoid arthritis. IV. Comparative evaluation of their effects on systemic (extra-articular) manifestations of the disease].
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Azathioprine; Child; Chlor | 1985 |
[Management strategy of chronic polyarthritis].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Azathioprin | 1985 |
Short term efficacy of methotrexate in the treatment of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Double-Blin | 1985 |
Anti-rheumatic drugs and joint damage in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Auranofin; Aurothioglucose; Blood Sedimentation; Ch | 1985 |
Reduced joint count indices in the evaluation of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Auranofin; Aurothioglucose; Azathioprine; Clinical Trials as Topic; Gold Sodi | 1985 |
[Comparative effectiveness of the basic drugs used in rheumatoid arthritis (long-term randomized study)].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chloroquine; Clinical Trials as Topic; Dimercaprol; | 1985 |
Controlled trial of D(-)penicillamine in severe rheumatoid arthritis.
Topics: Administration, Oral; Adult; Aged; Albuminuria; Anorexia Nervosa; Arthritis, Rheumatoid; Carbonates; | 1973 |
Penicillamine in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Drug Tolerance; Humans; Penicillamine | 1973 |
Editorial: Gold revalued.
Topics: Arthritis, Rheumatoid; Azathioprine; Clinical Trials as Topic; Cyclophosphamide; Dose-Response Relat | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Measurement of pain.
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Audiovisual Aids; Behavior; Clinical Trials as Topic; Go | 1974 |
Trial comparing D-penicillamine and gold in rheumatoid arthritis. Preliminary report.
Topics: Agglutination Tests; Arthritis, Rheumatoid; Blood Sedimentation; Clinical Trials as Topic; Feeding a | 1974 |
Immunosuppressive drugs in rheumatoid arthritis.
Topics: Adrenocorticotropic Hormone; Aminopterin; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Autoimmun | 1971 |
[D-penicillamine (Artamin) as basic therapeutic agent in the treatment of chronic rheumatoid arthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Sedimentation; Chronic Disease; Clinical Trials as Topic; | 1973 |
Penicillamine--an Anglo-American adventure in the treatment of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Humans; International Cooperation; Penicillamine; U | 1973 |
Controlled trial of penicillamine in severe rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Humans; Penicillamine; Time Factors | 1973 |
Penicillamine in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Costs and Cost Analysis; Humans; Penicillamine | 1973 |
Penicillamine in rheumatoid disease: a long-term study.
Topics: Agranulocytosis; Arthritis, Rheumatoid; Blood Sedimentation; Body Weight; Clinical Trials as Topic; | 1974 |
[100 cases of common rheumatoid polyarthritis, treated with D-penicillamin].
Topics: Adult; Aged; Antibody Specificity; Arthritis, Rheumatoid; Clinical Trials as Topic; Copper; Dyspepsi | 1974 |
Penicillamine for treatment of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Blood Sedimentation; Clinical Trials as Topic; Copper; Drug Evaluation; Gastr | 1974 |
Proceedings: Penicillamine or gold for rheumatoid arthritis? Multicentre trial using 'blind' observers. The first six months.
Topics: Arthritis, Rheumatoid; Blood Sedimentation; Clinical Trials as Topic; Female; Gold; Humans; Male; Pa | 1974 |
1003 other studies available for penicillamine and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Penicillamine-induced degenerative dermopathy in a patient with Wilson's disease.
Topics: Adult; Arthritis, Rheumatoid; Chelating Agents; Cystinuria; Hepatolenticular Degeneration; Humans; M | 2023 |
Tumor Necrosis Factor-α Inhibitor Use and the Risk of Incident Hypertension in Patients with Rheumatoid Arthritis.
Topics: Adalimumab; Adult; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine | 2016 |
Degradation of high-molar-mass hyaluronan by ascorbate plus cupric ions: effects of D-penicillamine addition.
Topics: Arthritis, Rheumatoid; Ascorbic Acid; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Humans; | 2009 |
Microalbuminuria in rheumatoid arthritis in the post penicillamine/gold era: association with hypertension, but not therapy or inflammation.
Topics: Aged; Albuminuria; Antirheumatic Agents; Arthritis, Rheumatoid; Biomarkers; Cardiovascular Diseases; | 2011 |
Physical signs for the general dental practitioner. Case 88. D-Penicillamine rash.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Diagnosis, Differential; Drug Eruptions; Exanthema; Gen | 2011 |
[Retrospective study of adverse events in patients with rheumatoid arthritis treated with second-line drugs].
Topics: Adult; Anorexia; Antirheumatic Agents; Arthritis, Rheumatoid; Exanthema; Female; Gastrointestinal Di | 2002 |
The rheumatoid arthritis patient in the clinic: comparing more than 1,300 consecutive DMARD courses.
Topics: Acute Disease; Aged; Antimalarials; Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Chron | 2002 |
Comparison of the effect of plasmapheresis and penicillamine on the level of circulating rheumatoid factor.
Topics: Arthritis; Arthritis, Rheumatoid; Chelating Agents; Humans; Immunologic Tests; Penicillamine; Plasma | 1963 |
[PSYCHOSIS DUE TO GOLD POISONING, TREATED WITH D-PENICILLAMINE].
Topics: Arthritis; Arthritis, Rheumatoid; Gold; Humans; Iatrogenic Disease; Mental Disorders; Penicillamine; | 1964 |
NEUTROPHILIC AGRANULOCYTOSIS DURING ADMINISTRATION OF PENICILLAMINE.
Topics: Adrenal Cortex Hormones; Agranulocytosis; Arthritis; Arthritis, Rheumatoid; Bone Marrow Examination; | 1964 |
RHEUMATOID ARTHRITIS WITH ARTERITIS; REPORT OF A CASE TREATED WITH PENICILLAMINE.
Topics: Amputation, Surgical; Arteritis; Arthritis; Arthritis, Rheumatoid; Drug Therapy; Foot Diseases; Gang | 1964 |
[ON THE BEHAVIOR OF THE RHEUMATOID FACTOR UNDER THE INFLUENCE OF PENICILLAMINE AND PENICILLIN IN PRIMARY CHRONIC POLYARTHRITIS (RHEUMATOID ARTHRITIS)].
Topics: Arthritis; Arthritis, Rheumatoid; Hemagglutination; Hemagglutination Tests; Humans; Immunologic Test | 1965 |
Effects of pro- and anti-inflammatory cytokines and nitric oxide donors on hyaluronic acid synthesis by synovial cells from patients with rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Female; H | 2004 |
[Minimal changes nephrotic syndrome associated to penicillamine treatment].
Topics: Adult; Arthritis, Rheumatoid; Autoimmune Diseases; Female; Humans; Immunosuppressive Agents; Middle | 2004 |
D-penicillamine-induced pemphigus vulgaris in a patient with scleroderma-rheumatoid arthritis overlap syndrome.
Topics: Arthritis, Rheumatoid; Female; Follow-Up Studies; Humans; Middle Aged; Pemphigus; Penicillamine; Ris | 2004 |
D-penicillamine-induced pemphigus successfully treated with combination therapy of mizoribine and prednisolone.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Drug Therapy, | 2004 |
Light chain multiple myeloma in a patient with long-standing rheumatoid arthritis.
Topics: Aged; Antineoplastic Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Gold Compounds; Hu | 2005 |
The inhibitory effect of disease-modifying anti-rheumatic drugs and steroids on gliostatin/platelet-derived endothelial cell growth factor production in human fibroblast-like synoviocytes.
Topics: Adrenal Cortex Hormones; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cells; Cells, Cul | 2005 |
Prolactin and autoimmune diseases in humans.
Topics: Aminoquinolines; Animals; Arthritis, Rheumatoid; Autoimmune Diseases; Bromocriptine; Cabergoline; Cy | 2007 |
The importance of the disease process and disease-modifying antirheumatic drug treatment in the development of septic arthritis in patients with rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Infectious; Arthritis, Rheumatoid; Female; Humans; Male; Methotrexa | 2007 |
Mechanism of action of the disease-modifying anti-arthritic thiol agents D-penicillamine and sodium aurothiomalate: restoration of cellular free thiols and sequestration of reactive aldehydes.
Topics: Aldehydes; Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Cell Line; Gold Sodium Thiomalate; | 2008 |
[Behavior of the rheumatoid factor under long-term penicillamine therapy in primary chronic polyarthritis and lupus erythematosus disseminatus].
Topics: Adolescent; Adult; Arthritis, Rheumatoid; Female; Hemagglutination Tests; Humans; Immunosuppressive | 1966 |
[Kidney diseases caused by drugs].
Topics: Acute Kidney Injury; Adult; Anemia; Arthritis, Rheumatoid; Dextrans; Drug-Related Side Effects and A | 1967 |
Neuromuscular transmission and acetylcholine receptor antibodies in rheumatoid arthritis patients on D-penicillamine.
Topics: Arthritis, Rheumatoid; Autoantibodies; Female; Humans; Middle Aged; Myasthenia Gravis; Neuromuscular | 1980 |
On the effects of antirheumatic drugs on protein sulphydryl reactivity in human serum.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Blood Proteins; Gold Sodium Thiomalate; Hu | 1980 |
A biochemical comparison of alclofenac and D-penicillamine in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Blood Sedimentation; Blood Viscosity; C-Reactive Protein; Humans; Penicillami | 1980 |
Anti-acetycholine receptor antibodies in penicillamine treated patients without myasthenia gravis.
Topics: Acetylcholine; Arthritis, Rheumatoid; Autoantibodies; Female; Humans; Male; Penicillamine; Receptors | 1980 |
Penicillamine-the therapeutic paradox.
Topics: Arthritis, Rheumatoid; Lymphocytes; Macrophages; Penicillamine | 1981 |
Reversible renal failure: associated with treatment with a beta-adrenergic receptor blocking drug and non-steroidal anti-inflammatory drugs.
Topics: Acute Kidney Injury; Adrenergic beta-Antagonists; Anti-Inflammatory Agents; Arthritis, Rheumatoid; C | 1982 |
Penicillamine nephropathy and iron.
Topics: Administration, Oral; Arthritis, Rheumatoid; Drug Interactions; Glomerulonephritis; Humans; Intestin | 1982 |
Deficient sulphoxidation status and D-penicillamine toxicity.
Topics: Arthritis, Rheumatoid; Humans; Penicillamine; Proteinuria; Sulfoxides; Thrombocytopenia | 1983 |
Eosinophilia in D-penicillamine therapy.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Cross-Sectional Studies; Dapsone; Eosinophilia; Fem | 1983 |
Rheumatoid arthritis: is serum vitamin B12 high in active disease?
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Penicillamine; Sulfasalazine; | 1984 |
Outcome of attempts to treat rheumatoid arthritis with gold, penicillamine, sulphasalazine, or dapsone.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Dapsone; Female; Gold Sodium Thiomalate; Humans; Mal | 1984 |
Controversy in the treatment of rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Cost-Benefit Analysis; Gold; Humans; Immunosuppressi | 1984 |
The long term effects of sulphasalazine in the treatment of rheumatoid arthritis and a comparative study with penicillamine.
Topics: Adult; Aged; Arthritis, Rheumatoid; Drug Eruptions; Drug Tolerance; Dyspepsia; Female; Humans; Male; | 1984 |
Sequential gold and penicillamine therapy in rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Drug Eruptions; gamma-Globulins; Gold; HLA Antigens; HLA-B Antigens; H | 1982 |
[The HLA-DR determinants in chronic inflammatory rheumatism].
Topics: Adult; Aged; Arthritis, Rheumatoid; Chondrocalcinosis; Drug Hypersensitivity; Epitopes; Female; Gold | 1983 |
The effects of the antirheumatic agents N-(2-carboxyphenyl)-4-chloroanthranilic acid disodium (CCA) and D-penicillamine on the NK and ADCC activities and interferon production of lymphocytes.
Topics: Antibody-Dependent Cell Cytotoxicity; Arthritis, Rheumatoid; Humans; In Vitro Techniques; Interferon | 1984 |
Prior gold therapy does not influence the adverse effects of D-penicillamine in rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Child; Drug Eruptions; Drug Interactions; Dysgeusia; | 1982 |
Multiple side effects of penicillamine therapy in one patient with rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Drug Eruptions; Humans; Lupus Erythematosus, Systemic; Male; Myastheni | 1982 |
[Antigenic markers of immunocompetent cells in rheumatoid synovial membrane].
Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal; Antigens, Surface; Arthritis, Rheumatoid; Glucocor | 1983 |
Cells with immunoregulatory function: the human macrophages and the effects of remittive drugs.
Topics: Arthritis, Rheumatoid; Auranofin; Aurothioglucose; Dose-Response Relationship, Drug; Gold; Gold Sodi | 1983 |
Optic neuropathy associated with penicillamine therapy in a patient with rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Fluorescein Angiography; Humans; Male; Middle Aged; Optic Nerve Diseases; Pap | 1984 |
[Therapy of rheumatoid arthritis].
Topics: Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Drug Administration Schedule; Gold; | 1984 |
[Transient gynecomastia during treatment with D-penicillamine].
Topics: Adult; Arthritis, Rheumatoid; Gynecomastia; Humans; Male; Penicillamine | 1984 |
Penicillamine-associated myasthenia gravis.
Topics: Arthritis, Rheumatoid; Electromyography; Female; Humans; Immunity, Cellular; Lymphocytes; Male; Midd | 1980 |
[Therapy of inflammatory and degenerative joint diseases].
Topics: Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chlorambucil; Cyclopho | 1980 |
Neuromuscular transmission in rheumatoid arthritis, with and without penicillamine treatment.
Topics: Analysis of Variance; Arthritis, Rheumatoid; Electric Stimulation; Electromyography; Humans; Nerve F | 1981 |
[A chemically induced polyneuropathy in chronic polyarthritis treated with D-penicillamine?].
Topics: Antibodies, Antinuclear; Arthritis, Rheumatoid; Cortisone; Female; Humans; Hypesthesia; Leg; Middle | 1983 |
[5-year treatment of rheumatoid polyarthritis with D-penicillamine].
Topics: Arthritis, Rheumatoid; Drug Evaluation; Gold; Humans; Penicillamine; Retrospective Studies; Time Fac | 1983 |
The effect of D-penicillamine on human myeloperoxidase, a mechanism for the efficacy of the drug in rheumatoid arthritis.
Topics: Amino Acids; Arthritis, Rheumatoid; Chlorides; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration | 1983 |
Monocyte superoxide anion production in rheumatoid arthritis: preliminary evidence for enhanced rates of superoxide anion production by monocytes from patients receiving penicillamine, sodium aurothiomalate and corticosteroids.
Topics: Adrenal Cortex Hormones; Anions; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Female; Gold Sodiu | 1984 |
The combined effect of ACTH (gel) and D-penicillamine on the functional disability of patients with RA.
Topics: Adrenocorticotropic Hormone; Aged; Arthritis, Rheumatoid; Drug Therapy, Combination; Gels; Humans; P | 1984 |
[Febrile reaction to D-penicillamine].
Topics: Adult; Arthritis, Rheumatoid; Female; Fever; Humans; Middle Aged; Penicillamine | 1984 |
Arthritis and rheumatism: old questions, new answers.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Aspirin; Go | 1984 |
[Lupus biology: incidence and development in 84 rheumatoid polyarthritis patients treated with D-penicillamine].
Topics: Adult; Aged; Antibodies, Antinuclear; Arthritis, Rheumatoid; DNA; Female; Follow-Up Studies; Humans; | 1984 |
D-Penicillamine induced toxicity in rheumatoid arthritis: the role of sulphoxidation status and HLA-DR3.
Topics: Adult; Aged; Arthritis, Rheumatoid; Biotransformation; Carbocysteine; Cysteine; Female; Histocompati | 1984 |
Dose-related nephrotic syndrome in penicillamine-treated rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Humans; Male; Nephrotic Syndrome; Penicillamine | 1984 |
Extracapillary glomerulonephritis with necrotizing vasculitis in D-penicillamine-treated rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Female; Fluorescent Antibody Technique; Glomerulonephritis; Humans; Microscop | 1983 |
The effect of drugs on serum histidine levels in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Captopril; Clofibrate; Drug Combinations; Female; H | 1983 |
A systematic survey of HLA-A,B,C and D antigens and drug toxicity in rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Cytotoxicity Tests, Immunologic; Dermatitis; Dimerca | 1984 |
The influence of D-penicillamine therapy on numbers of circulating immunoglobulin secreting cells in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Hemolytic Plaque Technique; Humans; Immunoglobulins; Leukocytes; Penicillamin | 1984 |
Immunopathology of penicillamine-induced glomerular disease.
Topics: Arthritis, Rheumatoid; Complement Activation; Fluorescent Antibody Technique; Glomerulonephritis; Hu | 1984 |
HLA antigens and acetylcholine receptor antibodies in penicillamine induced myasthenia gravis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Autoantibodies; Female; Histocompatibility Antigens Class II; HL | 1983 |
[Long-term drug therapy in inflammatory rheumatic diseases using chronic polyarthritis as an example. 2. Basic principles of long-term drug therapy: choice of optimal therapeutic agents].
Topics: Antimalarials; Arthritis, Rheumatoid; Azathioprine; Drug Therapy, Combination; Gold; Gold Sodium Thi | 1983 |
A clinical study of older age rheumatoid arthritis with comparison to a younger onset group.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Arthritis, Rheumatoid; Female; Gold Sodium Thio | 1983 |
Pattern of response to systematised drug therapy in rheumatoid arthritis in Indians.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Cyclophosphamide; Gold Sodium Thiomalate; Humans; I | 1983 |
Medical considerations and management of rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aurothioglucose; Drug Admi | 1983 |
HLA-DR antigens and proteinuria induced by aurothioglucose and D-penicillamine in patients with rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Aurothioglucose; Female; Genes, MHC Class II; Gold; HLA Antigens; HLA-DR Anti | 1983 |
Does second-line therapy affect the radiological progression of rheumatoid arthritis?
Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Sedimentation; Bone and Bones; Female; Gold Sodium Thiomal | 1984 |
HLA DR antigens and disease expression in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Female; Gold Sodium Thiomalate; Histocompatibility Antigens Class II; HLA-DR | 1984 |
A method of comparing the toxicities of disease suppressive agents: possible application to a comparison between D-penicillamine and chloroquine.
Topics: Arthritis, Rheumatoid; Chloroquine; Dose-Response Relationship, Drug; Double-Blind Method; Gold Sodi | 1984 |
Drug treatment of rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Auranofin; Aurothioglucose; Azathioprine; Chlorambu | 1984 |
[Possible mechanism of action of drugs in the basic therapy of rheumatoid arthritis: effect on platelet aggregation].
Topics: Adenosine Diphosphate; Adult; Arthritis, Rheumatoid; Auranofin; Aurothioglucose; Gold; Gold Sodium T | 1984 |
Glutathione and selenium in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Follow-Up Studies; Glutathione; Gold Sodium Thiomalate; | 1984 |
Decreased pokeweed mitogen-induced IgM and IgM rheumatoid factor synthesis in rheumatoid arthritis patients treated with gold sodium thiomalate or penicillamine.
Topics: Arthritis, Rheumatoid; Gold Sodium Thiomalate; Humans; Immunoglobulin M; In Vitro Techniques; Penici | 1984 |
Changes in zinc and zinc-dependent enzymes in rheumatoid patients during penicillamine treatment.
Topics: Adult; Aged; Alkaline Phosphatase; Arthritis, Rheumatoid; Carbonic Anhydrases; Erythrocytes; Female; | 1984 |
HLA antigens and toxicity to gold and penicillamine in rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Chloroquine; Female; Gene Frequency; Genetic Markers; Gold Sodium Thio | 1984 |
The relationship between aurothioglucose- and D-penicillamine-induced proteinuria.
Topics: Arthritis, Rheumatoid; Aurothioglucose; Gold; Histocompatibility Antigens Class II; HLA-DR Antigens; | 1984 |
[HLA antigens and side effects of gold and D-penicillamine in chronic polyarthritis].
Topics: Arthritis, Rheumatoid; Chronic Disease; Gold Sodium Thiomalate; HLA Antigens; Humans; Penicillamine | 1984 |
Changes in the growth and metabolism of cells cultured from normal, sclerotic and rheumatoid connective tissue brought about by D-penicillamine and by sodium salicylate.
Topics: Adult; Arthritis, Rheumatoid; Cell Division; Cells, Cultured; Fibroblasts; Glycosaminoglycans; Human | 1980 |
Morphea-like reaction to D-penicillamine therapy.
Topics: Adult; Arthritis, Rheumatoid; Drug Eruptions; Female; Humans; Penicillamine; Scleroderma, Localized; | 1981 |
Pemphigus-like eruption due to penicillamine.
Topics: Arthritis, Rheumatoid; Diagnosis, Differential; Drug Eruptions; Humans; Male; Middle Aged; Pemphigus | 1981 |
Penicillamine-induced lupus-like reaction in rheumatoid arthritis and vasculitis.
Topics: Adult; Antibodies, Antinuclear; Arthritis, Rheumatoid; Drug Eruptions; Female; Humans; Lupus Erythem | 1981 |
Determination of T lymphocyte subpopulations by monoclonal antibodies in rheumatoid arthritis. Influence of immunomodulating agents.
Topics: Adult; Aged; Antibodies, Monoclonal; Arthritis, Rheumatoid; Cytotoxicity, Immunologic; Humans; Levam | 1981 |
[Chlorbutin, azathioprine, D-penicillamine, and levamisole (Decaris) in the treatment of rheumatoid arthritis patients. I. Comparative analysis of side effects].
Topics: Arthritis, Rheumatoid; Azathioprine; Bronchial Spasm; Chlorambucil; Drug Eruptions; Dyspepsia; Human | 1981 |
[Changes in various humoral immunity indicators during the treatment of rheumatoid arthritis with D-penicillamine (cuprenil)].
Topics: Adult; Aged; Antibodies, Antinuclear; Antigen-Antibody Complex; Arthritis, Rheumatoid; DNA; Humans; | 1981 |
Efficacy and toxicity of D-penicillamine for rheumatoid disease in the elderly.
Topics: Adult; Age Factors; Aged; Arthritis, Rheumatoid; Drug Eruptions; Female; Gastrointestinal Diseases; | 1982 |
[Reactive SH-groups in clinical practice. Methodological notes].
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Citrates; Darkness; Diabetes Mellitus; | 1981 |
[Drugs capable of altering the course of rheumatoid arthritis].
Topics: Antimalarials; Arthritis, Rheumatoid; Dapsone; Gold; Humans; Immunization, Passive; Levamisole; Meta | 1984 |
Prevalence of decreased bone mass in rheumatoid arthritis. Relation to anti-inflammatory treatment.
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Bone and Bones; Calcium; Female; Gold; | 1984 |
[Myasthenic syndrome--complication of D-penicillamine therapy].
Topics: Arthritis, Rheumatoid; Electromyography; Female; Humans; Middle Aged; Muscular Diseases; Penicillami | 1984 |
Comparative therapeutics of canine and human rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; As | 1984 |
Myasthenic pseudo-internuclear ophthalmoplegia due to penicillamine.
Topics: Arthritis, Rheumatoid; Humans; Male; Middle Aged; Myasthenia Gravis; Ophthalmoplegia; Penicillamine | 1984 |
Studies on the metabolism of D-penicillamine and its interaction with probenecid in cystinuria and rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Cysteine; Cystinuria; Drug Therapy, Combination; Female; Humans; Male; Penici | 1984 |
[Drug-induced glomerular diseases].
Topics: Antihypertensive Agents; Arthritis, Rheumatoid; Gold; Humans; Kidney Diseases; Kidney Tubular Necros | 1984 |
[D-penicillamine therapy in rheumatoid arthritis: adverse reactions with 2 different administration regimens].
Topics: Arthritis, Rheumatoid; Drug Administration Schedule; Female; Humans; Male; Penicillamine | 1984 |
Hydroxychloroquine in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Humans; Hydroxychloroquine; Penicillamine | 1984 |
[Penicillamine treatment of rheumatoid arthritis. A clinical and radiological report from a period of 2 years].
Topics: Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Penicillamine; Radiography | 1984 |
Azathioprine as single drug in the treatment of rheumatoid arthritis induces complete suppression of natural killer cell activity.
Topics: Arthritis, Rheumatoid; Azathioprine; Female; Humans; Killer Cells, Natural; Male; Middle Aged; Penic | 1984 |
D-penicillamine in patients with rheumatoid arthritis. Serum levels, pharmacokinetic aspects, and correlation with clinical course and side effects.
Topics: Arthritis, Rheumatoid; Cysteine; Drug Administration Schedule; Humans; Intestinal Absorption; Kineti | 1984 |
Eosinophilia in rheumatoid patients treated with D-penicillamine.
Topics: Adult; Aged; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Eosinophilia; Female; Humans; | 1984 |
Dose, plasma concentration and response relationships of D-penicillamine in patients with rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Female; Humans; Kinetics; Male | 1984 |
D-penicillamine does not chelate gold.
Topics: Arthritis, Rheumatoid; Chelating Agents; Female; Gold; Humans; Male; Penicillamine | 1984 |
The use of slow-acting drugs in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Gold; Humans; Penicillamine; Time Factors | 1984 |
[Obliterative bronchiolitis in rheumatoid arthritis].
Topics: Adult; Arthritis, Rheumatoid; Bronchial Diseases; Female; Humans; Penicillamine | 1984 |
A comparison of therapies which may influence trace metals in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Ethylenediamines; Female; Humans; Male; Middle Aged; Penicillamine; Sulfates; | 1984 |
Clinical response in relation to dose of penicillamine in the treatment of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Follow-Up Studies; Humans; Penicillamine; R | 1984 |
Rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Drainage; Female; Gold; Humans; Male; Peni | 1984 |
Penicillamine-induced myositis. Observations and unique features in two patients and review of the literature.
Topics: Adult; Arthritis, Rheumatoid; Biopsy; Dermatomyositis; Eosinophilia; Histocompatibility Antigens Cla | 1984 |
Penicillamine-induced myasthenia in rheumatoid arthritis: its clinical and genetic features.
Topics: Adult; Aged; Arthritis, Rheumatoid; Complement System Proteins; Female; Histocompatibility Antigens | 1983 |
[D-penicillamine in the treatment of patients with rheumatoid arthritis].
Topics: Adult; Arthritis, Rheumatoid; Female; Humans; Latex Fixation Tests; Male; Middle Aged; Penicillamine | 1983 |
Antibodies to cellular antigens in Greek patients with autoimmune rheumatic diseases: anti-Ro(SSA) antibody a possible marker of penicillamine-D intolerance.
Topics: Adult; Aged; Antigens; Arthritis, Rheumatoid; Autoantibodies; Autoantigens; Autoimmune Diseases; Fem | 1984 |
HLA antigens and drug toxicity in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Gold; Histocompatibility Antigens Class II; HLA Antigens; HLA-DR3 Antigen; Hu | 1984 |
Effect of penicillamine on blood levels and urinary excretion of gold.
Topics: Aged; Arthritis, Rheumatoid; Gold; Humans; Kinetics; Middle Aged; Penicillamine | 1983 |
Medical management of rheumatoid arthritis with emphasis on the Western Pacific Region.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Asia; Aspirin; Gold; Human | 1983 |
[Pemphigus folliaceous following D-penicillamine in rheumatoid arthritis].
Topics: Arthritis, Rheumatoid; Humans; Male; Middle Aged; Pemphigus; Penicillamine | 1983 |
Penicillamine does not chelate gold (I).
Topics: Arthritis, Rheumatoid; Chelating Agents; Drug Interactions; Gold; Humans; Penicillamine; Structure-A | 1983 |
Renal biopsy appearances in rheumatoid disease.
Topics: Adult; Aged; Arthritis, Rheumatoid; Biopsy; Complement C3; Female; Fibrin; Glomerulonephritis; Gold; | 1983 |
Drug therapy in the management of rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Azathioprine; Gol | 1983 |
[Myasthenia gravis induced by D-penicillamine].
Topics: Arthritis, Rheumatoid; Female; Humans; Middle Aged; Myasthenia Gravis; Penicillamine | 1983 |
[Morphology and pathogenesis of penicillamine-induced nephropathy].
Topics: Adult; Alveolitis, Extrinsic Allergic; Arthritis, Rheumatoid; Biopsy; Female; Glomerulonephritis; Hu | 1983 |
Rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Gold; Humans; Penicillamine; Steroid | 1983 |
Diffuse fasciculations induced by D-penicillamine.
Topics: Arthritis, Rheumatoid; Fasciculation; Female; Humans; Middle Aged; Neurologic Manifestations; Penici | 1983 |
IgA deficiency and drug induced IgA deficiency in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Dimercaprol; Dysgammaglobulinemia; Female; Gold; Humans; IgA Def | 1983 |
[Rheumatoid arthritis, obliterating bronchiolitis and D-penicillamine. Apropos of a new case with ultrastructural examination and review of the literature].
Topics: Arthritis, Rheumatoid; Bronchi; Bronchial Diseases; Humans; Male; Middle Aged; Penicillamine; Progno | 1983 |
Penicillamine-induced dermatomyositis. A case history.
Topics: Aged; Arthritis, Rheumatoid; Dermatomyositis; Electromyography; Female; Humans; Penicillamine | 1983 |
Penicillamine: an anti-rheumatoid drug.
Topics: Antigen-Antibody Complex; Arthritis, Rheumatoid; Autoimmune Diseases; Drug Administration Schedule; | 1983 |
Practices, strategies, and motivations in treatment of rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Female; Gold; Humans; Hydroxychloroquine; Middle Aged; Patient Care Pl | 1983 |
Penicillamine in rheumatoid disease.
Topics: Arthritis, Rheumatoid; Gold; Humans; Penicillamine | 1983 |
A comparative trial of timegadine and D-penicillamine in rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Evaluation Studies as Topic; Female; G | 1983 |
Thrombotic thrombocytopenic purpura during penicillamine therapy in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Humans; Male; Middle Aged; Penicillamine; Platelet Count; Purpura, Thrombocyt | 1983 |
Haematuria occurring during antirheumatoid therapy.
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Gold; Hematuria; Humans; Male; Middle Aged; Penicillamin | 1984 |
Low density lymphocytes: their relationship to disease activity and to antirheumatic therapy.
Topics: Adult; Arthritis, Rheumatoid; Densitometry; Female; Gold; Humans; Lymphocyte Activation; Male; Middl | 1984 |
Spontaneous synthesis of IgM rheumatoid factor by blood mononuclear cells from patients with rheumatoid arthritis: effect of treatment with gold salts or D-penicillamine.
Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Sedimentation; Female; Gold; Humans; Immunoglobulin M; Mal | 1984 |
Penicillamine-induced myasthenia gravis.
Topics: Arthritis, Rheumatoid; Humans; Male; Middle Aged; Myasthenia Gravis; Penicillamine | 1984 |
Drug therapy in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Gold; Humans; Penicillamine | 1984 |
[Chlorbutin, azathioprine, d-penicillamine and dekaris (levamisole) in the treatment of rheumatoid arthritis patients. III. A comparative analysis of their effect on the morphological manifestations of synovitis based on puncture biopsy data].
Topics: Adult; Arthritis, Rheumatoid; Azathioprine; Biopsy, Needle; Drug Evaluation; Humans; Knee Joint; Lev | 1984 |
[D-penicillamine-induced myasthenia gravis].
Topics: Adult; Arthritis, Rheumatoid; Female; Humans; Myasthenia Gravis; Penicillamine | 1984 |
Resistant rheumatoid arthritis. What to do when conservative therapy doesn't work.
Topics: Antimalarials; Arthritis, Rheumatoid; Cytotoxins; Drug Resistance; Glucocorticoids; Gold; Humans; Im | 1984 |
Penicillamine therapy in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Hematuria; Humans; Middle Aged; Penicillamine; Proteinuria; Retr | 1984 |
Methods for assaying D-penicillamine in a clinical setting.
Topics: Arthritis, Rheumatoid; Chromatography, Gas; Chromatography, High Pressure Liquid; Cystinuria; Dose-R | 1984 |
Pharmacokinetics of the major metabolites of D-penicillamine in patients with rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Biotransformation; Chromatography, High Pressure Liquid; Cystein | 1984 |
Penicillamine metal chelates and their possible importance in rheumatoid arthritis--a brief review.
Topics: Arthritis, Rheumatoid; Chelating Agents; Copper; Gold; Humans; Metabolic Clearance Rate; Penicillami | 1984 |
Effects of D-penicillamine on inflammatory and immune reactions.
Topics: Antibody Formation; Antigen-Antibody Complex; Arthritis, Rheumatoid; Autoantibodies; Chemotaxis, Leu | 1984 |
Penicillamine and other remittive agents in rheumatoid arthritis: comparisons and interaction.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Drug Interactions; Gold; Humans; Penicillamine | 1984 |
Circulating immune complexes in patients with rheumatoid arthritis and the effect of penicillamine in vitro.
Topics: Antigen-Antibody Complex; Arthritis, Rheumatoid; Complement C3; Complement C4; Humans; Immunoglobuli | 1984 |
Selected adverse reactions of D-penicillamine.
Topics: Adult; Arthritis, Rheumatoid; Autoimmune Diseases; Bronchiolitis, Viral; Cholestasis; Female; Humans | 1984 |
Bio-inorganic effects of D-penicillamine in children and in the elderly.
Topics: Abnormalities, Drug-Induced; Aged; Arthritis, Juvenile; Arthritis, Rheumatoid; Child; Cystinuria; Fe | 1984 |
Emergencies in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Infectious; Arthritis, Rheumatoid; Carpal Tunnel Syndrome; Cerv | 1984 |
Lichenoid lesions of the oral mucosa in rheumatoid arthritis patients treated with penicillamine.
Topics: Administration, Topical; Adult; Aged; Arthritis, Rheumatoid; Betamethasone; Female; Humans; Lichen P | 1984 |
Thrombokinetics in patients with rheumatoid arthritis treated with D-penicillamine.
Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Platelets; Cell Survival; Humans; Middle Aged; Penicillami | 1984 |
Diffuse alveolitis on a small dose of penicillamine.
Topics: Arthritis, Rheumatoid; Humans; Male; Middle Aged; Penicillamine; Prednisolone; Pulmonary Fibrosis; R | 1984 |
Defective monocyte accessory function due to surface sulphydryl (SH) oxidation in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Cells, Cultured; Humans; Immunoglobulin G; Mercaptoethanol; Monocytes; Penici | 1984 |
Cardiac involvement in rheumatoid patients before and after D-penicillamine treatment--an echocardiographic study.
Topics: Adult; Aged; Arthritis, Rheumatoid; Echocardiography; Female; Heart Diseases; Heart Valve Diseases; | 1984 |
Scavenging of hydrogen peroxide--a new mechanism of action for D-penicillamine in rheumatoid arthritis?
Topics: Arthritis, Rheumatoid; Humans; Hydrogen Peroxide; Penicillamine | 1984 |
[Interactions between rheumatoid factors and antinuclear autoantibodies: their occurrence in a concealed state in rheumatoid disease (arthritis); effect of D-penicillamine].
Topics: Animals; Antibodies, Antinuclear; Arthritis, Rheumatoid; Humans; Immunoglobulin G; Immunoglobulin M; | 1980 |
HLA-DR antigens and toxic reaction to sodium aurothiomalate and D-penicillamine in patients with rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Gold Sodium Thiomalate; Histocompatibility Testing; HLA | 1980 |
Adverse reactions to D-penicillamine after gold toxicity.
Topics: Arthritis, Rheumatoid; Gold Sodium Thiomalate; Humans; Penicillamine; Proteinuria; Skin Diseases | 1980 |
The glomerular filtration rate during penicillamine therapy in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Chromium Radioisotopes; Creatinine; Edetic Acid; Female; Glomeru | 1980 |
Successful treatment of D-penicillamine-induced breast gigantism with danazol.
Topics: Adult; Arthritis, Rheumatoid; Breast; Breast Diseases; Danazol; Estradiol; Female; Humans; Hypertrop | 1981 |
[Is myositis in chronic polyarthritis using d-penicillamine drug-induced?].
Topics: Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Gold Sod | 1981 |
Relationship of gold and penicillamine therapy to diffuse interstitial lung disease.
Topics: Adult; Arthritis, Rheumatoid; Dyspnea; Female; Gold Sodium Thiomalate; Humans; Lung; Male; Middle Ag | 1981 |
Proteinuria in rheumatoid arthritis--drug-induced or amyloid?
Topics: Adult; Aged; Amyloidosis; Arthritis, Rheumatoid; Gold Sodium Thiomalate; Humans; Kidney Diseases; Ki | 1981 |
[Rheumatology forum. 5. Alternatives in rheumatism therapy].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aurothioglucose; Humans; Penicillamine | 1981 |
Enteric-coated aspirin in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Aspirin; Blood Sedimentation; Gold Sodium Thiomalate; Humans; Hydroxychloroqu | 1981 |
[Effect of D-penicillamine on serum immunoglobulins in rheumatoid arthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Humans; Immunodiffusion; Immunoglobulin A; Immunoglobuli | 1981 |
Interim observations on benefit/risk of azathioprine versus D-penicillamine in the treatment of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Azathioprine; Double-Blind Method; Humans; Long-Term Care; Middle Aged; Penic | 1982 |
Drugs in the management of rheumatoid arthritis.
Topics: Antibiotics, Antineoplastic; Antimalarials; Arthritis, Rheumatoid; Gold Sodium Thiomalate; Humans; P | 1982 |
Reversible gynaecomastia associated with D-penicillamine in a man with rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Gynecomastia; Humans; Male; Penicillamine | 1982 |
Influence of previous gold toxicity on subsequent development of penicillamine toxicity.
Topics: Arthritis, Rheumatoid; Gold; Humans; Penicillamine | 1982 |
Rheumatoid arthritis V: therapy with remission-inducing agents.
Topics: Arthritis, Rheumatoid; Gold Sodium Thiomalate; Humans; Hydroxychloroquine; Penicillamine | 1982 |
Altered thiol status in patients with rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Cells; Copper; Female; Gold Sodium Thiomalate; Humans; Lev | 1982 |
Fatal polymyositis in D-penicillamine-treated rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Female; Heart Block; Humans; Middle Aged; Myocarditis; Myositis; Penicillamin | 1983 |
IgG and IgM rheumatoid factors in rheumatoid arthritis. Quantitative response to penicillamine therapy and relationship to disease activity.
Topics: Adult; Arthritis, Rheumatoid; Blood Sedimentation; Female; Humans; Immunoglobulin G; Immunoglobulin | 1983 |
[Basic therapy of rheumatoid arthritis with D-penicillamine. Personal contribution and critical observations].
Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Arthritis, Rheumatoid; Child; Female; Fever; Humans; | 1983 |
Penicillamine compared to previous chrysotherapy in rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Female; Gold; Humans; Male; Middle Aged; Penicillami | 1983 |
Risk/benefit analysis of hydroxychloroquine sulfate treatment in rheumatoid arthritis.
Topics: Actuarial Analysis; Arthritis, Rheumatoid; Gastrointestinal Diseases; Gold; Humans; Hydroxychloroqui | 1983 |
[Retrospective study of the effects of D-penicillamine and pyrithioxin in the treatment of rheumatoid arthritis].
Topics: Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Penicillamine; Pyridines; Pyrithioxin; Ret | 1983 |
Role of penicillamine for the induction of myasthenia gravis.
Topics: Animals; Arthritis, Rheumatoid; Autoantibodies; DNA; Lymphocytes; Mice; Mice, Inbred Strains; Mice, | 1983 |
Upper and lower airway disease in penicillamine treated patients with rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Biopsy; Bronchitis; Female; Gold; Humans; Lung; Lung Diseases; Male; Middle A | 1983 |
Slow-acting antirheumatic drugs.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Azathioprine; Chloroquine; Cyclophosphamide; Gold; | 1982 |
Autoimmune associations in primary biliary cirrhosis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Autoimmune Diseases; Female; Humans; Immunoglobulins; Keratoconj | 1982 |
The year's new drugs.
Topics: Analgesics; Anti-Bacterial Agents; Arthritis, Rheumatoid; Dantrolene; Humans; Metoclopramide; Penici | 1980 |
Pharmacist on call. Penicillamine: newest weapon against rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Humans; Penicillamine | 1980 |
[Drug therapy of rheumatoid arthritis].
Topics: Antineoplastic Agents; Arthritis, Rheumatoid; Bee Venoms; Chloroquine; Chronic Disease; Drug Therapy | 1980 |
Therapeutic uses of copper-chelating agents.
Topics: Arthritis, Rheumatoid; Chemical Phenomena; Chemistry; Copper; Glutathione; Humans; Hydrogen-Ion Conc | 1980 |
Association of HLA-DRw4 with rheumatoid arthritis in black and white patients.
Topics: Adult; Aged; Arthritis, Rheumatoid; Black People; Gold; Histocompatibility Antigens Class II; HLA An | 1980 |
Treatment of rheumatoid arthritis with levamisole.
Topics: Arthritis, Rheumatoid; Blood Sedimentation; Dose-Response Relationship, Drug; Humans; Levamisole; Pe | 1980 |
HLA antigens in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Gold; HLA Antigens; Humans; Inflammation; Major Histocompatibility Complex; P | 1980 |
Microscopic haematuria in patients with rheumatoid arthritis on d-penicillamine.
Topics: Arthritis, Rheumatoid; False Positive Reactions; Hematuria; Humans; Penicillamine; Urinary Tract Inf | 1981 |
Medical management and its impact on work.
Topics: Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Female; | 1982 |
Systemic lupus erythematosus during penicillamine therapy for rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Drug Hypersensitivity; Female; Histocompatibility Antigens Class | 1982 |
HLA system and side effects of gold salts and D-penicillamine treatment of rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Dimercaprol; Female; Gold; Histocompatibility Antigens Class II; | 1982 |
Therapeutics of antirheumatic agents.
Topics: Arthritis, Rheumatoid; Humans; Naproxen; Penicillamine; Rheumatic Diseases | 1980 |
Circulating protein complexes in D-penicillamine therapy of rheumatoid arthritis. Correlation between IgG- and alpha 1-antitrypsin-IgA complexes and clinical response.
Topics: alpha 1-Antitrypsin; Arthritis, Rheumatoid; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobul | 1980 |
Drug effects on autoantibodies and immune complexes.
Topics: Acetylation; Antibodies, Antinuclear; Antigen-Antibody Complex; Arthritis, Rheumatoid; Autoantibodie | 1980 |
The heterogeneity of serologic findings and predisposing host factors in drug-induced lupus erythematosus.
Topics: Acetylation; Antibodies, Antinuclear; Antilymphocyte Serum; Arthritis, Rheumatoid; Complement Fixati | 1981 |
Hidden anti-nuclear antibodies in rheumatic diseases.
Topics: Antibodies, Antinuclear; Arthritis, Rheumatoid; Collagen Diseases; Fluorescent Antibody Technique; H | 1980 |
Penicillamine-associated pemphigus: is it really pemphigus?
Topics: Arthritis, Rheumatoid; Diagnosis, Differential; Female; Fluorescent Antibody Technique; Humans; Midd | 1981 |
Herpetiform pemphigus-like skin lesions induced by D-penicillamine.
Topics: Adult; Arthritis, Rheumatoid; Diagnosis, Differential; Female; Humans; Male; Middle Aged; Pemphigus; | 1980 |
D-Penicillamine-induced severe pneumonitis.
Topics: Aged; Arthritis, Rheumatoid; Female; Gold; Humans; Penicillamine; Pneumonia; Pulmonary Alveoli; Pulm | 1982 |
Effects of levamisole and D-penicillamine on contact sensitivity to oxazolone in rats.
Topics: Anaphylaxis; Animals; Arthritis, Rheumatoid; Dermatitis, Contact; Female; Levamisole; Oxazoles; Oxaz | 1982 |
An overview of benefit/risk of disease modifying treatment of rheumatoid arthritis as of today.
Topics: Arthritis, Rheumatoid; Azathioprine; Chloroquine; Cyclophosphamide; Female; Gold; Humans; Hydroxychl | 1982 |
Pharmacokinetics of reduced D-penicillamine in patients with rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Humans; Kinetics; Male; Middle Aged; Oxidation-Reduction | 1982 |
Hypocupremia-related hypochromic anemia during D-penicillamine treatment.
Topics: Anemia, Hypochromic; Arthritis, Rheumatoid; Copper; Female; Humans; Middle Aged; Penicillamine | 1982 |
D-Penicillamine--induced pemphigus syndrome.
Topics: Aged; Arthritis, Rheumatoid; Complement C3; Erythema; Humans; Immunoglobulin G; Male; Pemphigus; Pen | 1982 |
Serum concanavalin-A binding in rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Blood Viscosity; C-Reactive Protein; Concanavalin A; | 1982 |
Age and arthritis.
Topics: Adult; Age Factors; Aged; Arthritis; Arthritis, Rheumatoid; England; Female; Gold; Humans; Male; Mid | 1982 |
[Minimal lesion nephrotic syndrome following treatment with D-penicillamine].
Topics: Adult; Arthritis, Rheumatoid; Female; Humans; Kidney Glomerulus; Middle Aged; Nephrosis, Lipoid; Pen | 1982 |
D-Penicillamine-associated myasthenia gravis: immunological and electrophysiological studies.
Topics: Adult; Arthritis, Rheumatoid; Autoantibodies; Electromyography; Female; Humans; Immunoglobulin G; Im | 1982 |
Gold and penicillamine therapy: is shared care with general practitioners effective and safe?
Topics: Arthritis, Rheumatoid; Communication; Drug Therapy, Combination; Gold; Humans; Outpatient Clinics, H | 1982 |
[Membranous glomerulonephritis caused by D-penicillamine].
Topics: Adult; Arthritis, Rheumatoid; Female; Glomerulonephritis; Humans; Kidney Glomerulus; Nephrotic Syndr | 1982 |
[Chlorbutin, azathioprine, D-penicillamine and dekaris (levamisole) in the treatment of rheumatoid arthritis. Comparative analysis of their effect on the indices of disease activity and progression].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Azathioprine; Chlorambucil; Chronic Disease; Drug E | 1982 |
Concurrent naproxen- and penicillamine-induced renal disease in rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Female; Glomerulonephritis; Humans; Kidney Diseases; Naproxen; Nephrit | 1982 |
Controlled multicenter trial of tiopronin and d-penicillamine for rheumatoid arthritis.
Topics: Aged; Amino Acids, Sulfur; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Blood Sedimentation; Cli | 1982 |
D-penicillamine-induced polymyositis.
Topics: Adult; Arthritis, Rheumatoid; Female; Humans; Myositis; Penicillamine | 1982 |
Obliterative bronchiolitis in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Bronchitis; Female; Humans; Middle Aged; Penicillamine; Respiratory Function | 1982 |
[Penicillin-induced liver involvement in rheumatoid arthritis. A review illustrated by a case report].
Topics: Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Female; Humans; Male; Middle Aged; Pe | 1982 |
[Pemphigus caused by D-penicillamine].
Topics: Arthritis, Rheumatoid; Female; Humans; Middle Aged; Pemphigus; Penicillamine | 1982 |
Repigmentation of vitiligo under penicillamine therapy for rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Humans; Male; Penicillamine; Vitiligo | 1982 |
[Determination of glutathione and D-penicillamine using a high performance liquid chromatography with a voltammetric detector].
Topics: Adult; Arthritis, Rheumatoid; Chromatography, High Pressure Liquid; Glutathione; Humans; Male; Penic | 1982 |
D-penicillamine in rheumatoid arthritis: laboratory findings with particular reference to complement and immunoglobulins.
Topics: Adult; Aged; Arthritis, Rheumatoid; Complement System Proteins; Female; Humans; Immunoglobulins; Mal | 1982 |
[Myasthenia gravis pseudoparalytica as a result of penicillamine treatment of rheumatoid arthritis].
Topics: Arthritis, Rheumatoid; Female; Humans; Middle Aged; Myasthenia Gravis; Penicillamine | 1982 |
[Strategy of treatment of rheumatoid polyarthritis].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Gold; Humans; Levamisole; | 1982 |
Therapeutic update. Clinical strategy in rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Gold; Humans; Imm | 1982 |
[A case of rheumatoid arthritis associated with leukocytopenia during D-penicillamine treatment].
Topics: Arthritis, Rheumatoid; Female; Humans; Leukopenia; Middle Aged; Penicillamine | 1982 |
Concept of conservative treatment.
Topics: Antidepressive Agents; Arthritis, Rheumatoid; Azathioprine; Gold; Humans; Penicillamine; Prednisone | 1982 |
Levamisole: possibilities of immunomodulation in the basic treatment of rheumatoid arthritis. Clinical and immunological observations in a one-year decaris treatment of rheumatoid arthritis patients.
Topics: Arthritis, Rheumatoid; Female; Humans; Levamisole; Male; Penicillamine | 1981 |
The relationship between D-penicillamine--induced proteinuria and prior gold nephropathy.
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Gold; HLA Antigens; Humans; Kidney Diseases; Male; Middl | 1981 |
[Extramembranous glomerulonephritis induced by D-penicillamine. Description of a case].
Topics: Arthritis, Rheumatoid; Diabetes Complications; Female; Glomerulonephritis; Humans; Middle Aged; Peni | 1981 |
Nephrotic syndrome in a patient with rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; Biopsy; Female; Humans; Hyperlipoproteinemias; Kidney; Kidney Glomerulu | 1981 |
Cholestasis associated with D-penicillamine therapy: case report and review of the literature.
Topics: Adult; Arthritis, Rheumatoid; Cholestasis; Drug Hypersensitivity; Eosinophils; Female; Humans; Leuko | 1981 |
Obliterative bronchiolitis in two rheumatoid arthritis patients treated with penicillamine.
Topics: Arthritis, Rheumatoid; Bronchitis; Drug Hypersensitivity; Female; Humans; Middle Aged; Necrosis; Pen | 1981 |
[Pharmacology of collagen].
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Colchicine; Collagen; Humans; Levamisole; | 1981 |
[Polymyositis induced by D-penicillamine].
Topics: Adrenal Cortex Hormones; Adult; Aged; Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Musc | 1981 |
Good response to D-penicillamine in IgA-deficient rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Dysgammaglobulinemia; Female; Humans; IgA Deficiency; Middle Aged; Penicillam | 1981 |
Penicillamine in 1980.
Topics: Animals; Antigen-Antibody Complex; Arthritis, Rheumatoid; Autoantibodies; Disease Models, Animal; Dr | 1981 |
Penicillamine-induced dermatomyositis.
Topics: Arthritis, Rheumatoid; Humans; Male; Middle Aged; Myositis; Penicillamine | 1981 |
Pemphigus in rheumatoid arthritis treated with penicillamine.
Topics: Arthritis, Rheumatoid; Female; Humans; Middle Aged; Pemphigus; Penicillamine; Skin | 1981 |
Cholestatic hepatitis caused by penicillamine.
Topics: Arthritis, Rheumatoid; Bile Ducts, Intrahepatic; Chemical and Drug Induced Liver Injury; Cholestasis | 1981 |
[D-penicillamine induced myasthenic syndromes in rheumatoid arthritis. Two cases (author's transl)].
Topics: Adult; Arthritis, Rheumatoid; Autoantibodies; Female; Humans; Middle Aged; Muscles; Myasthenia Gravi | 1981 |
[Severe bronchiolitis in 3 cases of rheumatoid polyarthritis treated with D-penicillamine].
Topics: Adult; Arthritis, Rheumatoid; Bronchopneumonia; Female; Humans; Middle Aged; Penicillamine | 1981 |
D-penicillamine in pregnancy--to ban or not to ban?
Topics: Arthritis, Rheumatoid; Connective Tissue Diseases; Cystinuria; Female; Hepatolenticular Degeneration | 1981 |
Rheumatoid arthritis. Guidelines for office management.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Gold; Humans; Penicillamine; Physical Ther | 1981 |
Pulmonary eosinophilia caused by penicillamine.
Topics: Arthritis, Rheumatoid; Female; Humans; Middle Aged; Penicillamine; Pulmonary Eosinophilia | 1980 |
Penicillamine-induced myasthenia gravis in a patient with rheumatoid arthritis. A case report.
Topics: Adult; Arthritis, Rheumatoid; Female; Humans; Myasthenia Gravis; Penicillamine | 1981 |
Penicillamine-induced neuropathy in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Female; Humans; Middle Aged; Nervous System Diseases; Neural Conduction; Peni | 1981 |
Penicillamine-induced polymyositis in a patient with rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Humans; Male; Middle Aged; Myositis; Penicillamine | 1981 |
[Long-term clinical follow-up studies of basic therapy in rheumatoid arthritis].
Topics: Adult; Aged; Anti-Inflammatory Agents; Antineoplastic Agents; Arthritis, Rheumatoid; Female; Follow- | 1981 |
[Age factors and basic therapy of rheumatoid arthritis].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Age Factors; Aged; Arthritis, Rheumatoid; Gold; Humans; | 1981 |
[Indices of nonspecific resistance in the basic therapy of rheumatoid arthritis].
Topics: Adrenal Cortex Hormones; Antilymphocyte Serum; Arthritis, Rheumatoid; Female; Humans; Immunity, Inna | 1981 |
[Follow-up study of patients with rheumatoid arthritis over a period of more than 10 years (1966-1978): analysis of disease progression and treatment in 100 cases (author's transl)].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Chlorambuci | 1981 |
[Basic therapeutic drugs for rheumatoid arthritis].
Topics: Arthritis, Rheumatoid; Chloroquine; Gold; Humans; Immunosuppressive Agents; Penicillamine | 1981 |
[Respiratory complications in the course of treatment with D-penicillamine : alveolitis and bronchiolitis. A report of 4 cases (author's transl)].
Topics: Aged; Arthritis, Rheumatoid; Bronchial Diseases; Female; Humans; Lung Diseases; Male; Middle Aged; P | 1981 |
Action of D-penicillamine on immunocomplexes containing rheumatoid factor.
Topics: Antigen-Antibody Complex; Antigen-Antibody Reactions; Arthritis, Rheumatoid; Humans; Immunoglobulin | 1981 |
Rheumatoid vasculitis.
Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Cyclophosphamide; Humans; Penicillamine; Vasculitis | 1981 |
[Obliterating bronchiolitis in rheumatoid arthritis. Responsibility of D-penicillamine].
Topics: Adult; Arthritis, Rheumatoid; Bronchitis; Female; Humans; Penicillamine; Pulmonary Fibrosis | 1981 |
[Pregnancy and rheumatic disease (author's transl)].
Topics: Arthritis, Rheumatoid; Female; Gold; Humans; Penicillamine; Pregnancy; Pregnancy Complications; Scle | 1981 |
[Agranulocytosis and myasthenia gravis probably induced by D-penicillamine in rheumatoid patients (author's transl)].
Topics: Agranulocytosis; Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Myasthenia Gravis; Penici | 1981 |
D-penicillamine and the ocular myasthenic syndrome.
Topics: Arthritis, Rheumatoid; Blepharoptosis; Diplopia; Female; Humans; Middle Aged; Myasthenia Gravis; Pen | 1981 |
D-penicillamine: before, during, or after?
Topics: Arthritis, Rheumatoid; Humans; Penicillamine | 1981 |
[Myasthenia in rheumatoid arthritis treated with D-penicillamine: 2 cases].
Topics: Adult; Arthritis, Rheumatoid; Female; Humans; Middle Aged; Myasthenia Gravis; Penicillamine | 1981 |
Serum SH reactivity: a simple assessment of D-penicillamine absorption?
Topics: Absorption; Arthritis, Rheumatoid; Drug Therapy, Combination; Evaluation Studies as Topic; Ferrous C | 1981 |
Toxicity of D-penicillamine in rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Drug Interactions; Gold; Humans; Kid | 1980 |
Adverse effects of D-penicillamine in rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Drug Administration Schedule; Gastrointestinal Disea | 1980 |
[Penicilliamine in rheumatoid arthritis].
Topics: Arthritis, Rheumatoid; Humans; Penicillamine | 1980 |
The toxicity pattern of D-penicillamine therapy. A guide to its use in rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Blood Sedimentation; Child; Digestive System; Dose-R | 1980 |
Polymyositis with acute myolysis in a patient with rheumatoid arthritis treated with penicillamine and ampicillin.
Topics: Acute Disease; Adult; Ampicillin; Arthritis, Rheumatoid; Female; Humans; Muscular Diseases; Myositis | 1980 |
[D-penicillamine-induced pemphigus].
Topics: Arthritis, Rheumatoid; Female; Humans; Middle Aged; Pemphigus; Penicillamine; Recurrence; Skin | 1980 |
[Penicillamine and rheumatoid arthritis. Recent research results].
Topics: Arthritis, Rheumatoid; Drug Evaluation; Humans; Immunoglobulin M; Norway; Penicillamine | 1980 |
Penicillamine treatment in rheumatoid arthritis. A retrospective study.
Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Sedimentation; Female; Humans; Male; Middle Aged; Orosomuc | 1980 |
Early rheumatoid arthritis in the USSR and in Finland.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Antineoplastic Agents; Arthritis, Rheumatoid; Chloroquin | 1980 |
Penicillamine-induced pemphigus.
Topics: Arthritis, Rheumatoid; Female; Humans; Middle Aged; Pemphigus; Penicillamine | 1980 |
Effect of homologous synovial membrane on adult human articular cartilage in organ culture, and failure to influence it with D-penicillamine.
Topics: Adult; Arthritis, Rheumatoid; Cartilage, Articular; Galactosamine; Glucosamine; Humans; Organ Cultur | 1980 |
Drug treatment in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Gold; Humans; Penicillamine | 1980 |
[Sulfhydryl-based treatment of rheumatoid arthritis (penicillamine, pyrithioxin, thiopronine)].
Topics: Amino Acids, Sulfur; Arthritis, Rheumatoid; Humans; Penicillamine; Pyridines; Pyrithioxin; Sulfhydry | 1980 |
[Tiopronine: new basic treatment for rheumatoid arthritis. Open study of 158 cases].
Topics: Adult; Aged; Amino Acids, Sulfur; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Double-Bl | 1980 |
A comparison of clinical assessments of disease activity in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Blood Sedimentation; C-Reactive Protein; Humans; Hydroxychloroquine; Penicill | 1980 |
Hepatotoxicity associated with use of D-penicillamine in rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Female; Humans; Male; Middle A | 1980 |
Renal disease in rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Glomerulonephritis; Gold; Humans; Kidney; Male; Microscopy, Electron; | 1980 |
Progressive rheumatoid arthritis: how far should we go with medical therapy?
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Gold; Humans; Penicillamin | 1980 |
D-penicillamine-induced bronchial spasm.
Topics: Adolescent; Arthritis, Rheumatoid; Bronchial Spasm; Edema; Female; Humans; Male; Middle Aged; Penici | 1980 |
Penicillamine in rheumatoid arthritis: a clinical guide.
Topics: Arthritis, Rheumatoid; Humans; Monitoring, Physiologic; Penicillamine; Proteinuria | 1980 |
[Use of D-penicillamine for the treatment of rheumatoid arthritis and the study of various mechanisms of its action].
Topics: Adult; Arthritis, Rheumatoid; Cells, Cultured; Collagen; Female; Fibroblasts; Humans; Middle Aged; P | 1980 |
[Our experience in the treatment of rheumatoid arthritis with D-penicillamine].
Topics: Adult; Aged; Arthritis, Rheumatoid; Humans; Middle Aged; Penicillamine | 1980 |
Penicillamine: twenty-five years later.
Topics: Arthritis, Juvenile; Arthritis, Rheumatoid; Hepatolenticular Degeneration; Humans; Penicillamine | 1980 |
[Treatment of rheumatoid arthritis with prolonged-action drugs].
Topics: Aminoquinolines; Arthritis, Rheumatoid; Chlorambucil; Chloroquine; Glucocorticoids; Gold; Humans; Im | 1980 |
[A case of malignant rheumatoid arthritis associated with myasthenia gravis by D-penicillamine treatment (author's transl)].
Topics: Arthritis, Rheumatoid; Female; Humans; Middle Aged; Myasthenia Gravis; Penicillamine | 1980 |
Myasthenia gravis and penicillamine therapy of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Autoantibodies; Humans; Male; Middle Aged; Myasthenia Gravis; Penicillamine; | 1980 |
[Fatal medullary aplasia after administration of D penicillamine for rheumatoid arthritis].
Topics: Aged; Arthritis, Rheumatoid; Bone Marrow Diseases; Female; Humans; Penicillamine | 1980 |
[Prolonged neuromuscular blockade during a D. penicillamine-induced myasthenia (author's transl)].
Topics: Adult; Alcuronium; Arthritis, Rheumatoid; Female; Humans; Myasthenia Gravis; Neuromuscular Junction; | 1980 |
[Squamous eruption of the lichen planus histological type during treatment with pyritinol].
Topics: Aged; Arthritis, Rheumatoid; Humans; Lichen Planus; Male; Penicillamine; Pyridines; Pyrithioxin | 1980 |
[Administration of D-penicillamine instead of penicillin with fatal results: allergy of the delayed type with protracted shock as fatal complication of treatment with D-penicillamine for rheumatoid arthritis in a child (author's transl)].
Topics: Arthritis, Rheumatoid; Autopsy; Child; Drug Hypersensitivity; Female; Humans; Malpractice; Penicilla | 1980 |
Penicillamine nephropathy.
Topics: Adult; Aged; Arthritis, Rheumatoid; Biopsy; Female; Humans; Kidney; Kidney Diseases; Male; Middle Ag | 1980 |
[Obliterating bronchiolitis during D-penicillamine treatments].
Topics: Adrenal Cortex Hormones; Adult; Arthritis, Rheumatoid; Female; Humans; Lung Diseases, Obstructive; M | 1980 |
Discriminatory indices of response of patients with rheumatoid arthritis treated with D-penicillamine.
Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Sedimentation; C-Reactive Protein; Drug Administration Sch | 1980 |
Plasma zinc and its relationship to clinical symptoms and drug treatment in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Blood Proteins; Blood Sedimentation; Female; Humans | 1980 |
Dermatomyositis induced by penicillamine.
Topics: Arthritis, Rheumatoid; Dermatomyositis; Female; Humans; Middle Aged; Penicillamine | 1980 |
[Hematotoxic lesions caused by non-steroidal antirheumatic agents].
Topics: Adult; Aged; Agranulocytosis; Anemia, Aplastic; Arthritis, Rheumatoid; Aspirin; Diclofenac; Female; | 1980 |
Survival analysis of disease modifying antirheumatic drugs in Spanish rheumatoid arthritis patients.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Female; Humans; Male; Methotrexate; | 1995 |
Acquired sideroblastic anaemia associated with penicillamine therapy for rheumatoid arthritis.
Topics: Anemia, Sideroblastic; Arthritis, Rheumatoid; Diabetes Mellitus, Type 2; Humans; Male; Middle Aged; | 1995 |
D-penicillamine induced myasthenia gravis in rheumatoid arthritis: an unpredictable common occurrence?
Topics: Aged; Arthritis, Rheumatoid; Female; HLA Antigens; Humans; Male; Middle Aged; Myasthenia Gravis; Pen | 1994 |
Antimalarial drug induced decrease in creatinine clearance.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Chloroquine; Creatinine; Fema | 1995 |
[A case of agranulocytosis which occurred several hours after the readministration of D-penicillamine accompanied by shivering-chillness].
Topics: Agranulocytosis; Arthritis, Rheumatoid; Female; Humans; Middle Aged; Penicillamine | 1995 |
Microalbuminuria in patients with rheumatoid arthritis.
Topics: Adult; Aged; Aged, 80 and over; Albuminuria; Antirheumatic Agents; Arthritis, Rheumatoid; Blood Sedi | 1995 |
Reduced sulphoxidation capacity in D-penicillamine induced myasthenia gravis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Myasthenia Gravis; Penicillam | 1994 |
Combination therapy for rheumatoid arthritis and drug-induced systemic lupus erythematosus.
Topics: Adult; Arthritis, Rheumatoid; Drug Therapy, Combination; Female; Humans; Lupus Erythematosus, System | 1994 |
The total costs of drug therapy for rheumatoid arthritis. A model based on costs of drug, monitoring, and toxicity.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Boston; Decision Trees; Diagnosis-Related | 1995 |
D-penicillamine-induced myasthenia gravis: diagnosis obscured by coexisting chronic obstructive pulmonary disease.
Topics: Aged; Arthritis, Rheumatoid; Female; Humans; Hypoventilation; Lung Diseases, Obstructive; Male; Midd | 1995 |
A disease activity index: its use in clinical trials and disease assessment in patients with rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Drug Therapy, Combination; Hu | 1993 |
The use of the disease activity score in the analysis of clinical trials in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Blood Sedimentation; Clinical Trials as Topic; Gold Sodium Thiomalate; Humans | 1993 |
Rheumatoid arthritis and AIDS.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Arthritis, Rheumatoid; CD | 1994 |
[Myasthenia caused by D-penicillamine in rheumatoid arthritis].
Topics: Adult; Arthritis, Rheumatoid; Female; Humans; Myasthenia Gravis; Penicillamine | 1994 |
Sulphoxidation status in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Humans; Penicillamine; Sulfasalazine; Sulfoxides | 1993 |
Optimizing the assessment of disease activity during treatment with anti-rheumatoid drugs.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Cytidine Deaminase; Female; Gold; Humans; Hydroxych | 1993 |
Suspected cutaneous drug toxicity in rheumatoid arthritis--an evaluation.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, | 1993 |
Variability in individual responses of 532 patients with rheumatoid arthritis to first-line and second-line drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; | 1993 |
Reduced joint counts in controlled clinical trials in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Gold Sodium Thiomalate; Humans; Joints; Methotrexate; Penicillamine; Randomiz | 1994 |
Unilateral ptosis as an initial manifestation of D-penicillamine induced myasthenia gravis.
Topics: Adult; Arthritis, Rheumatoid; Blepharoptosis; Female; Humans; Myasthenia Gravis; Penicillamine; Scle | 1993 |
D-penicillamine induced polymyositis causing complete heart block.
Topics: Arthritis, Rheumatoid; Complement System Proteins; Female; Heart Block; Humans; Immunoglobulins; Mid | 1994 |
A western blot approach to detection of human plasma protein conjugates derived from D-penicillamine.
Topics: Arthritis, Rheumatoid; Blood Proteins; Blotting, Western; Cells, Cultured; Dose-Response Relationshi | 1994 |
[Morphological pictures of renal biopsy specimens in glomerulopathies related to rheumatoid arthritis (RA)].
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Biopsy; Female; G | 1994 |
[D-penicillamine-induced myasthenia gravis].
Topics: Aged; Arthritis, Rheumatoid; Autoantibodies; Female; Humans; Myasthenia Gravis; Penicillamine; Pyrid | 1994 |
D-penicillamine and polymyositis: the significance of the anti-Jo-1 antibody.
Topics: Antibodies; Antibodies, Antinuclear; Arthritis, Rheumatoid; Female; Humans; Middle Aged; Penicillami | 1993 |
[A case of rheumatoid arthritis with obstructive bronchiolitis appearing after D-penicillamine therapy].
Topics: Arthritis, Rheumatoid; Bronchiolitis; Female; Humans; Middle Aged; Oxygen Inhalation Therapy; Penici | 1993 |
Penicillamine-induced rapidly progressive glomerulonephritis in a patient with rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; Female; Glomerulonephritis; Humans; Penicillamine | 1993 |
[Analysis of the state of patients with rheumatoid arthritis using a personal computer].
Topics: Age Factors; Arthritis, Rheumatoid; Cysteine; Databases, Factual; Female; Gold Sodium Thiomalate; Hu | 1993 |
The long-term use of D-penicillamine for treating rheumatoid arthritis: is continuous therapy necessary?
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Chromatography, High Pressure Liquid; Clinica | 1993 |
Regulation of B cell function by bucillamine, a novel disease-modifying antirheumatic drug.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; B-Lymphocytes; Copper; Cystei | 1993 |
Apparent cure of rheumatoid arthritis by bone marrow transplantation.
Topics: Adult; Anemia, Aplastic; Arthritis, Rheumatoid; Bone Marrow Transplantation; Female; Gold; Hand; Hem | 1993 |
Systemic lupus erythematosus-like syndrome with focal proliferative glomerulonephritis during D-penicillamine therapy.
Topics: Arthritis, Rheumatoid; Cyclophosphamide; Female; Glomerulosclerosis, Focal Segmental; Humans; Lupus | 1993 |
[Pemphigus foliaceus caused by penicillamine].
Topics: Aged; Aged, 80 and over; Arthritis, Rheumatoid; Complement C3; Drug Eruptions; Female; Fluorescent A | 1993 |
Concurrent pemphigus and myasthenia gravis as manifestations of penicillamine toxicity.
Topics: Arthritis, Rheumatoid; Female; Humans; Middle Aged; Myasthenia Gravis; Pemphigus; Penicillamine | 1993 |
[Myasthenia induced by penicillamine: does an interaction with tricyclic antidepressants exist?].
Topics: Aged; Antidepressive Agents, Tricyclic; Arthritis, Rheumatoid; Autoimmune Diseases; Drug Interaction | 1993 |
D-penicillamine and gold salt treatments were complicated by myasthenia and pemphigus, respectively, in the same patient with rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Immunocompromised Host; Middle Aged; My | 1995 |
Factors associated with the development of vasculitis in rheumatoid arthritis: results of a case-control study.
Topics: Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid | 1996 |
[Myasthenia gravis caused by D-penicillamine].
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Myasthenia Gravis; Penicillamine | 1996 |
Rheumatoid arthritis lung disease. Determinants of radiographic and physiologic abnormalities.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Cohort Studies; Female; Gold; Humans; Lung Disea | 1996 |
Membranous glomerulonephritis in rheumatoid arthritis unrelated to gold, D-penicillamine or other connective tissue disease.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Female; Glomerulonephritis, Membranous; Gold; Humans; I | 1996 |
Bone alkaline phosphatase in rheumatoid arthritis: a longitudinal study.
Topics: Aged; Alkaline Phosphatase; Arthritis, Rheumatoid; Bone and Bones; Female; gamma-Glutamyltransferase | 1996 |
C1 inhibitor deficiency in a patient with rheumatoid arthritis--increased risk of adverse effects of penicillamine?
Topics: Angioedema; Arthritis, Rheumatoid; Child; Complement C1 Inactivator Proteins; Glomerulonephritis; Hu | 1996 |
Pancytopenia related eosinophilia in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Eosinophilia; Humans; Methotrexate; Pancytopenia; Penicillamine | 1996 |
Human gelatinase B, a marker enzyme in rheumatoid arthritis, is inhibited by D-penicillamine: anti-rheumatic activity by protease inhibition.
Topics: Anti-Bacterial Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Biomarkers; Collagenases; Deferi | 1996 |
D-penicillamine-induced myositis in rheumatoid arthritis.
Topics: Adult; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Biopsy, Needle; Electr | 1996 |
Variations and trends in the prescription of initial second line therapy for patients with rheumatoid arthritis.
Topics: Antimalarials; Antirheumatic Agents; Arthritis, Rheumatoid; Auranofin; Female; Gold; Humans; Male; M | 1997 |
Urinary 6 beta-hydroxycortisol excretion in rheumatoid arthritis.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Energy Metabolism; Female; Gold Sodium Thi | 1997 |
Response to therapy in rheumatoid arthritis is influenced by immediately prior therapy.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, | 1997 |
Effect of resumption of second line drugs in patients with rheumatoid arthritis that flared up after treatment discontinuation.
Topics: Acute Disease; Aged; Antimalarials; Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Femal | 1997 |
[Focal segmental glomerulosclerosis presenting nephrotic syndrome and acute renal failure in a patient with rheumatoid arthritis].
Topics: Acute Kidney Injury; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumati | 1997 |
Matrix metalloproteinase 13 (collagenase 3) in human rheumatoid synovium.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Cartilage, Articular; Clodronic Acid; Collage | 1997 |
[Rheumatoid arthritis. Conservative therapeutic possibilities today and in the future].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, R | 1998 |
Therapeutic effect of tiopronin following D-penicillamine toxicity in a patient with rheumatoid arthritis.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Humans; Jaundice; Male; Penicillamine; Retreatme | 1998 |
Methotrexate in rheumatoid arthritis: a 2 year experience at a university hospital in Pakistan.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Drug Therapy, Combination; Fe | 1998 |
Thymoma associated with rheumatoid arthritis after D-penicillamine treatment.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Penicillamine; Thymoma; Thymus Ne | 1998 |
Pharmacological effects of SA96 (bucillamine) and its metabolites as immunomodulating drugs--the disulfide structure of SA-96 metabolites plays a critical role in the pharmacological action of the drug.
Topics: Adjuvants, Immunologic; Adult; Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic | 1998 |
Penicillamine in the etiology of bullous pemphigoid.
Topics: Administration, Oral; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Glucocorticoids; Humans; | 1998 |
The therapeutic response to D-penicillamine in rheumatoid arthritis: influence of glutathione S-transferase polymorphisms.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Female; Genotype; Glutathione Transferase; Haplotypes; | 1999 |
[D-penicillamine-induced pemphigus, polymyositis and myasthenia].
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Biopsy; Female; Humans; Muscles; Myasthenia Gravi | 1999 |
Successful treatment of methotrexate induced nodulosis with D-penicillamine.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Methotrexate; Middle Aged; Penici | 1999 |
Successful treatment of recalcitrant penicillamine-induced pemphigus foliaceus by low-dose intravenous immunoglobulins.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Drug Eruptions; Female; Humans; Immunoglobulins, Intrav | 1999 |
Long-term application of disease modifying antirheumatic drugs (DMARD). A single-center, observational study of 1681 patients with rheumatoid arthritis (RA).
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Chloroquine; Dose-Response R | 1999 |
[MPO-ANCA positive rapidly progressive glomerulonephritis in a patient with rheumatoid arthritis during treatment with D-penicillamine].
Topics: Adult; Antibodies, Antineutrophil Cytoplasmic; Antirheumatic Agents; Arthritis, Rheumatoid; Chronic | 1999 |
Induction of COX-2 expression by nitric oxide in rheumatoid synovial cells.
Topics: Arthritis, Rheumatoid; Base Sequence; Cells, Cultured; Cyclooxygenase 2; DNA Primers; Enzyme Inducti | 2000 |
Bucillamine suppresses human Th1 cell development by a hydrogen peroxide-independent mechanism.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; CD4-Positive T | 2000 |
In vitro and in vivo inhibition of activation induced T cell apoptosis by bucillamine.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies; Antirheumatic Agents; Apoptosis; Arthr | 2000 |
Rapidly progressive glomerulonephritis with D-penicillamine.
Topics: Adult; Antibodies, Antineutrophil Cytoplasmic; Antirheumatic Agents; Arthritis, Rheumatoid; Disease | 2000 |
Effects of nitric oxide on matrix metalloproteinase-2 production by rheumatoid synovial cells.
Topics: Arthritis, Rheumatoid; Cell Culture Techniques; Culture Media, Conditioned; Humans; Matrix Metallopr | 2001 |
Nitric oxide protects cultured rheumatoid synovial cells from Fas-induced apoptosis by inhibiting caspase-3.
Topics: Apoptosis; Arthritis, Rheumatoid; Caspase 3; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cel | 2001 |
[A case of rheumatoid arthritis associated with minimal change nephrotic syndrome].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans | 2001 |
Clinical aspects: specificity and mode of action of immunosuppressives.
Topics: Animals; Antimalarials; Arthritis, Rheumatoid; Azathioprine; Gold; Humans; Immunosuppressive Agents; | 1976 |
[Vascular polyneuropathy in rheumatoid arthritis (author's transl)].
Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Azathioprine; Humans; Male; Middle Aged; Penicillami | 1977 |
If I had... Severe rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Dapsone; Gold; Humans; Pen | 1978 |
Gamma glutamyl transpeptidase levels in arthritis: a correlation with clinical and laboratory indices of disease activity.
Topics: Aged; Arthritis, Rheumatoid; Female; gamma-Glutamyltransferase; Humans; Male; Middle Aged; Osteoarth | 1978 |
Limited plasmapheresis in rheumatoid arthritis with vasculitis.
Topics: Antigen-Antibody Complex; Arthritis, Rheumatoid; Azathioprine; Blood Sedimentation; Complement C3; C | 1979 |
Effects of antirheumatic drugs on protein sulphydryl reactivity of human serum.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Blood Proteins; Gold Sodium Thiomalate; Humans; In | 1979 |
Connective tissue changes in rheumatoid arthritis and the use of penicillamine. Proceedings of a Review Symposium held in Rotterdam, 9-10 March 1979, under the auspices of the "Gerrit Jan Mulder Foundation".
Topics: Animals; Arthritis, Rheumatoid; Congresses as Topic; Connective Tissue; Humans; Netherlands; Penicil | 1979 |
[Panarteritis nodosa in rheumatoid arthritis. Report of a case].
Topics: Arthritis, Rheumatoid; Chlorambucil; Female; Humans; Middle Aged; Penicillamine; Polyarteritis Nodos | 1979 |
Letter: Effect of penicillamine on peripheral-blood lymphocytes in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Drug Therapy, Combination; Female; Humans; Immunosuppression The | 1975 |
Drug treatment of rheumatoid arthritis. A systematic approach.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Drug Evalua | 1975 |
Letter: D-penicillamine-induced membranous glomerulonephritis.
Topics: Arthritis, Rheumatoid; Glomerulonephritis; Hepatitis; Humans; Penicillamine; Proteinuria | 1975 |
Editorial: D-penicillamine in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Blood Cell Count; Drug Eruptions; Humans; Penicillamine; Proteinuria; Thrombo | 1975 |
Letter: Marrow aplasia and penicillamine.
Topics: Anemia, Aplastic; Arthritis, Rheumatoid; Bone Marrow; Female; Humans; Middle Aged; Penicillamine; Sc | 1976 |
Letter: Zinc, penicillamine, and rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Drug Interactions; Humans; Penicillamine; Zinc | 1976 |
Fatal marrow aplasia in patient on penicillamine.
Topics: Aged; Anemia, Aplastic; Arthritis, Rheumatoid; Female; Humans; Penicillamine | 1976 |
Toxic hepatitis after therapeutic doses of benorylate and D-penicillamine.
Topics: Adolescent; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Drug Synergism; Drug Ther | 1977 |
Drug-induced IgA deficiency in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Dysgammaglobulinemia; Female; Gold Sodium Thiomalate; Humans; Immunoglobulin | 1977 |
Penicillamine and iron.
Topics: Arthritis, Rheumatoid; Copper; Drug Antagonism; Humans; Intestinal Absorption; Iron; Penicillamine | 1976 |
Inhibition of the denaturation of human gamma globulin by a mixture of D-penicillamine disulfide and copper. A possible mechanism of action of D-penicillamine in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Blood Viscosity; Copper; Depression, Chemical; gamma-Globulins; Hot Temperatu | 1978 |
Anti-acetylcholine receptor antibodies in D-penicillamine-associated myasthenia gravis.
Topics: Acetylcholine; Adult; Arthritis, Rheumatoid; Autoantibodies; Female; Humans; Male; Middle Aged; Myas | 1978 |
Chronic lymphocytic leukaemia after treatment with penicillamine.
Topics: Arthritis, Rheumatoid; Female; Humans; Leukemia, Lymphoid; Middle Aged; Penicillamine | 1978 |
Contact reaction to penicillamine in vaginal secretions.
Topics: Adult; Arthritis, Rheumatoid; Coitus; Drug Hypersensitivity; Female; Humans; Male; Menstruation; Pen | 1979 |
Increased intracellular glutathione during penicillamine treatment for rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; Erythrocytes; Female; Glutathione; Humans; Penicillamine; Time Factors | 1979 |
Dermatomyositis induced by penicillamine.
Topics: Arthritis, Rheumatoid; Dermatomyositis; Female; Humans; Middle Aged; Penicillamine | 1979 |
Precipitating autoantibody to a ubiquitous tissue antigen: association with rheumatoid arthritis treated with sodium aurothiomalate or d-penicillamine.
Topics: Adolescent; Adult; Aged; Animals; Antigen-Antibody Reactions; Arthritis, Rheumatoid; Autoantibodies; | 1978 |
Do penicillamine and Myocrisin act the same way in rheumatoid arthritis?
Topics: Animals; Arthritis, Rheumatoid; Gold Sodium Thiomalate; Humans; In Vitro Techniques; Penicillamine; | 1978 |
Trace elements in serum and urine of patients with rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Copper; Gold Sodium Thiomalate; Humans; Iron; Penicillamine; Protein Binding; | 1978 |
Gold and penicillamine: a proposed mode of action in rheumatoid arthritis, based on synovial fluid analysis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Gold Sodium Thiomalate; Humans; Immu | 1978 |
Gold and thiol compounds in the treatment of rheumatoid arthritis: excretory fate and tissue distribution of thiomalate in relation to gold after administration of myocrisin (auro-thiomalate).
Topics: Animals; Arthritis, Rheumatoid; Cell Membrane; Cell Membrane Permeability; Chromatography, Gas; Gold | 1979 |
Gold in the treatment of rheumatoid arthritis -- why, when and how?
Topics: Arthritis, Rheumatoid; Chloroquine; Dose-Response Relationship, Drug; Gold; Gold Sodium Thiomalate; | 1979 |
Effect of penicillamine on the kidney.
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Humans; Kidney Diseases; Male; Middle Aged; Penicillamin | 1977 |
Myasthenia associated with D-penicillamine therapy in rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Humans; Male; Middle Aged; Myasthenia Gravis; Penicillamine | 1977 |
Penicillamine treatment of rheumatoid arthritis: relationship of proteinuria and autoantibodies to immune status.
Topics: Arthritis, Rheumatoid; Autoantibodies; Humans; Immunoglobulins; Penicillamine; Proteinuria | 1977 |
Penicillamine treatment of rheumatoid arthritis with a single daily dose of 250 mg.
Topics: Arthritis, Rheumatoid; Humans; Penicillamine | 1977 |
Rheumatoid arthritis treated with small doses of penicillamine.
Topics: Arthritis, Rheumatoid; Humans; Penicillamine | 1977 |
The influence of drug therapy on serum immunoglobulin profiles in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Humans; Immunoglobulins; Penicillamine | 1977 |
Pemphigus-like syndrome induced by D-penicillamine.
Topics: Arthritis, Rheumatoid; Drug Eruptions; Female; Humans; Middle Aged; Pemphigus; Penicillamine; Syndro | 1976 |
[Glomerulopathy in rheumatic patients due to penicillamine].
Topics: Adult; Antigen-Antibody Complex; Arthritis, Rheumatoid; Female; Glomerulonephritis; Humans; Kidney; | 1976 |
Side-effects of long-term D-penicillamine therapy in rheumatoid arthritis.
Topics: Agranulocytosis; Arthritis, Rheumatoid; Drug Eruptions; Female; Humans; Middle Aged; Neutropenia; Pe | 1977 |
Simultaneous occurrence of perimembranous glomerulonephritis and glomerular amyloidosis.
Topics: Amyloidosis; Arthritis, Rheumatoid; Biopsy; Female; Glomerulonephritis; Humans; Kidney; Kidney Disea | 1978 |
Penicillamine and previous treatment with gold.
Topics: Arthritis, Rheumatoid; Bone Marrow Diseases; Drug Eruptions; Gold; Humans; Penicillamine; Sjogren's | 1978 |
[Pemphigus syndrome in D-penicillamine treated rheumatoid arthritis].
Topics: Adult; Arthritis, Rheumatoid; Drug Eruptions; Female; Humans; Pemphigus; Penicillamine; Syndrome | 1978 |
Two cases of penicillamine-induced pemphigus erythematosus.
Topics: Aged; Arthritis, Rheumatoid; Azathioprine; Drug Eruptions; Female; Humans; Middle Aged; Pemphigus; P | 1979 |
D-penicillamine and immune complex deposition.
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Humans; Immune Complex Diseases; Lupus Erythematosus, Sy | 1979 |
Nursing care study. Rheumatoid arthritis treated with penicillamine.
Topics: Adrenocorticotropic Hormone; Adult; Arthritis, Rheumatoid; Aspirin; Humans; Male; Penicillamine | 1975 |
[Pharmacotherapy of progressive polyarthritis].
Topics: Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Gold; H | 1977 |
Gold-induced thrombocytopenia.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Arthritis, Rheumatoid; Dimercaprol; Female; Gold Sodium Th | 1978 |
[Rheumatoid polyarthritis].
Topics: Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Cortiso | 1978 |
Effects of D-penicillamine on lymphocyte modulation of synovial collagenase production.
Topics: Arthritis, Rheumatoid; Humans; In Vitro Techniques; Lymphocytes; Microbial Collagenase; Penicillamin | 1979 |
A study of the influence of various antirheumatic drug regimens on serum acute-phase proteins, plasma tryptophan, and erythrocyte sedimentation rate in rheumatoid arthritis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Blood Proteins; Bloo | 1975 |
Drugs: distamine.
Topics: Adult; Arthritis, Rheumatoid; Child; Hepatolenticular Degeneration; Humans; Lead Poisoning; Penicill | 1979 |
New non-steroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Fenoprofen; Humans; Ibuprofen; Naproxen; Penicillam | 1977 |
Clinical evaluation of novel anti-rheumatic drugs.
Topics: Arthritis, Rheumatoid; Double-Blind Method; Drug Evaluation; Female; Humans; Levamisole; Penicillami | 1977 |
The place of levamisole in the armamentarium for rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Chloroquine; Gold; Humans; Levamisole; Penicillamine | 1978 |
Adverse reactions to the principal drugs used in rheumatoid arthritis--a review.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chloroquine; Gold; Humans; Immunosuppressive Agents | 1978 |
D-penicillamine in the treatment of rheumatoid vasculitis.
Topics: Arthritis, Rheumatoid; Humans; Male; Middle Aged; Penicillamine; Vasculitis | 1979 |
D-penicillamine: biochemical, metabolic and pharmacological aspects.
Topics: Aldehydes; Arthritis, Rheumatoid; Chemical Phenomena; Chemistry; Chromatography, Gel; Collagen; Huma | 1979 |
Liver abnormalities in penicillamine treated rheumatoid arthritis.
Topics: Aged; Alanine Transaminase; Alkaline Phosphatase; Arthritis, Rheumatoid; Aspartate Aminotransferases | 1979 |
Influence of D-penicillamine treatment on the humoral immune system.
Topics: Administration, Oral; Animals; Antibody Formation; Arthritis, Rheumatoid; Humans; Immunoglobulin A; | 1979 |
The inhibitory effect of D-penicillamine on human lymphocyte cultures stimulated by phytohaemagglutinin, the antagonistic action of L-cysteine and synergistic inhibition by copper sulphate.
Topics: Adult; Arthritis, Rheumatoid; Blood; Cells, Cultured; Copper; Culture Media; Cysteine; Drug Synergis | 1979 |
Penicillamine in rheumatoid arthritis: clinical pharmacology and biochemical properties.
Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Collagen; Cystine; Drug Evaluation; Humans; Penicillamin | 1979 |
Some aspects of the mechanism of action of penicillamine in rheumatoid arthritis.
Topics: Aldehydes; Animals; Arthritis, Rheumatoid; Cell Membrane; Chemical Phenomena; Chemistry; Collagen; D | 1979 |
Myasthenia associated with D-penicillamine therapy in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Humans; Myasthenia Gravis; Penicillamine | 1979 |
Surveillance costs of gold and penicillamine.
Topics: Arthritis, Rheumatoid; Costs and Cost Analysis; Gold; Humans; Penicillamine; Proteinuria; Reagent Ki | 1979 |
Some aspects of slow-acting drugs in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Chloroquine; Dapsone; Gold; Humans; Immunosuppression Therapy; Levamisole; Pe | 1979 |
Blood levels and side-effects of D-penicillamine.
Topics: Arthritis, Rheumatoid; Copper; Cysteine; Humans; Kinetics; Penicillamine | 1979 |
Proliferative lesion of arthritis: a target for therapy?
Topics: Arthritis, Rheumatoid; Connective Tissue; Humans; Penicillamine; Phagocytosis; Synovial Membrane | 1979 |
Difficulties in the use of D-penicillamine in the treatment of rheumatoid arthritis.
Topics: Adolescent; Adult; Arthritis, Rheumatoid; Biopsy; Dose-Response Relationship, Drug; Female; Humans; | 1979 |
[Are antinuclear factors a contraindication for penicillamine treatment in patients with rheumatoid arthritis? (author's transl)].
Topics: Antibodies, Antinuclear; Antibody Formation; Antibody Specificity; Arthritis, Rheumatoid; DNA; Human | 1978 |
Rheumatoid arthritis therapy: the risk/benefit ratio.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Gold; Huma | 1978 |
[Number of T and B-lymphocytes in the peripheral blood in rheumatoid arthritis relative to the disease activity, the serum immunoglobulin level and the drug therapy].
Topics: Arthritis, Rheumatoid; Azathioprine; B-Lymphocytes; Cell Count; Gold; Humans; Ifosfamide; Immunoglob | 1978 |
The management of rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; | 1978 |
[Effect of Cuprenil (penicillamine) on peripheral blood lymphocytes and their T and B populations in patients with rheumatoid arthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; B-Lymphocytes; Female; Humans; Male; Middle Aged; Penicillamine; | 1978 |
Factors affecting the development of penicillamine side-effects.
Topics: Agglutination Tests; Antibodies, Antinuclear; Arthritis, Rheumatoid; Humans; Immunoglobulins; Latex | 1978 |
Antirheumatic therapy.
Topics: Antimalarials; Arthritis, Rheumatoid; Gold; Humans; Penicillamine; Rheumatic Diseases | 1979 |
D-penicillamine treatment in rheumatoid arthritis monitored by plasma alfa-1-antitrypsin-IgA complexes and plasma and urinary sulphur containing aminoacids.
Topics: alpha 1-Antitrypsin; Amino Acids, Sulfur; Arthritis, Rheumatoid; Collagen; Cystine; Humans; Immunogl | 1979 |
Effects of oral administration of D-penicillamine on T- and B-lymphocytes in peripheral blood of rheumatoid patients.
Topics: Adult; Arthritis, Rheumatoid; B-Lymphocytes; Dose-Response Relationship, Drug; Female; Humans; Immun | 1979 |
Drug treatment of arthritis in the elderly.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Gold; Humans; Immunos | 1979 |
[Muscular changes in rheumatoid arthritis and other rheumatic disorders].
Topics: Arthritis, Rheumatoid; Chloroquine; Humans; Muscles; Muscular Diseases; Penicillamine; Rheumatic Dis | 1979 |
Changes in the collagen of synovial membrane in rheumatoid arthritis and effect of D-penicillamine.
Topics: Aged; Aging; Arthritis, Rheumatoid; Collagen; Culture Techniques; Electrophoresis, Polyacrylamide Ge | 1978 |
Interactions between IgM antiglobulins and IgG antinuclear antibodies. Some aspects of D-penicillamine activities.
Topics: Antibodies, Anti-Idiotypic; Antibodies, Antinuclear; Antigen-Antibody Complex; Arthritis, Rheumatoid | 1979 |
Cytogenetic studies in patients treated with penicillamine.
Topics: Arthritis, Rheumatoid; Bone Marrow; Chromosome Aberrations; Chromosomes, Human; Dose-Response Relati | 1979 |
[Long-term treatment of chronic rheumatoid arthritis with D-penicillamin (author's transl)].
Topics: Adult; Aged; Arthritis, Rheumatoid; Chronic Disease; Female; Humans; Long-Term Care; Male; Middle Ag | 1977 |
Penicillamine-induced myasthenia gravis.
Topics: Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Myasthenia Gravis; Penicillamine | 1979 |
Cholestasis associated with d-penicillamine therapy for rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Cholestasis; Female; Humans; Penicillamine | 1979 |
Rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Gold; Humans; Imm | 1979 |
Bronchiolitis and bronchitis in connective tissue disease. A possible relationship to the use of penicillamine.
Topics: Adult; Arthritis, Rheumatoid; Bronchitis; Collagen Diseases; Eosinophils; Fascia; Female; Humans; In | 1979 |
Skin collagen biosynthesis in patients with rheumatoid arthritis treated with D-penicillamine.
Topics: Adult; Aged; Arthritis, Rheumatoid; Collagen; Female; Humans; Male; Middle Aged; Penicillamine; Prot | 1979 |
Plasmapheresis and lymphoplasmapheresis in the management of rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Evaluation Studies as Topic; Female; Gold; Humans; Immunoglobulins; In | 1979 |
Determination of D-penicillamine in serum and urine of patients with rheumatoid arthritis.
Topics: Amino Acids; Arthritis, Rheumatoid; Chromatography, Ion Exchange; Humans; Penicillamine | 1979 |
Penicillamine-induced neuromyotonia.
Topics: Arthritis, Rheumatoid; Female; Humans; Middle Aged; Myotonia; Neuromuscular Diseases; Penicillamine | 1979 |
[D-penicillamine in rheumatoid arthritis].
Topics: Arthritis, Rheumatoid; Humans; Penicillamine | 1979 |
[Pemphigus caused by D-penicillamine during treatment of rheumatoid arthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Pemphigus; Penicillamine; Pru | 1979 |
Resumption of treatment with penicillamine after proteinuria.
Topics: Arthritis, Rheumatoid; Drug Administration Schedule; Female; Humans; Penicillamine; Proteinuria | 1979 |
Myelotoxicity of D-penicillamine.
Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Cell Count; Bone Marrow Diseases; Female; Humans; Male; Mi | 1979 |
Penicillamine causing acute colitis.
Topics: Acute Disease; Arthritis, Rheumatoid; Colitis; Female; Humans; Middle Aged; Penicillamine | 1979 |
Management of rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antimalarials; Antineoplastic Agents; Arthritis, | 1979 |
[Acetylation phenotype in rheumatoid arthritis and the D-penicillamine treatment].
Topics: Acetylation; Acetyltransferases; Adolescent; Adult; Arthritis, Rheumatoid; Female; Humans; Male; Mid | 1979 |
[D-Penacillamine. From constituent of penicillins to significant drug].
Topics: Arthritis, Rheumatoid; Cystinuria; Hepatitis; Hepatolenticular Degeneration; Humans; Multiple Sclero | 1979 |
[Effect of clinical activity and D-penicillamine or gold treatment on the occurrence of serum immune complexes in patients with rheumatoid arthritis].
Topics: Antigen-Antibody Complex; Arthritis, Rheumatoid; Gold; Humans; Immunoglobulin G; Penicillamine | 1979 |
Maintenance dose of penicillamine in rheumatoid arthritis: a comparison between a standard and a response-related flexible regimen.
Topics: Adult; Aged; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Drug Administration Schedule; | 1979 |
D-penicillamine in the treatment of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Humans; Penicillamine | 1979 |
[Iatrogenic pulmonary pathology in patients with rheumatoid arthritis treated with D-penicillamine].
Topics: Arthritis, Rheumatoid; Humans; Lung Diseases; Penicillamine | 1979 |
[Rheumatoid arthritis with vasculitis treated with penicillamine and corticosteroids].
Topics: Adrenal Cortex Hormones; Aged; Arteritis; Arthritis, Rheumatoid; Humans; Male; Penicillamine; Skin U | 1979 |
[Granulomatous hepatitis and parotiditis induced by d-penicillamine in a case of rheumatoid arthritis].
Topics: Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Female; Humans; Indoleacetic Acids; M | 1979 |
Penicillamine-induced myasthenia gravis associated with antibodies to acetylcholine receptor.
Topics: Adult; Arthritis, Rheumatoid; Autoantibodies; Female; Humans; Myasthenia Gravis; Penicillamine; Rece | 1978 |
[Undesirable effects of D-penicillamine in the therapy of rheumatoid arthritis].
Topics: Ageusia; Arthritis, Rheumatoid; Humans; Kidney Diseases; Myasthenia Gravis; Penicillamine; Proteinur | 1979 |
[Azapropazone plasma levels in rheumatologic therapy with D-penicillamine combined with immunosuppressive agents].
Topics: Adult; Apazone; Arthritis, Rheumatoid; Azathioprine; Drug Therapy, Combination; Humans; Immunosuppre | 1977 |
[Urinary xanthurenic acid levels].
Topics: Age Factors; Aged; Alcoholism; Arthritis, Rheumatoid; Child; Contraceptives, Oral; Diabetes Mellitus | 1978 |
Herpetiform pemphigus induced by penicillamine.
Topics: Arthritis, Rheumatoid; Dermatitis Herpetiformis; Diagnosis, Differential; Humans; Male; Middle Aged; | 1977 |
Penicillamine in seronegative polyarthritis.
Topics: Arthritis, Rheumatoid; Humans; Penicillamine; Spondylitis, Ankylosing | 1977 |
Penicillamine in rheumatoid arthritis: wound healing, skin thickness and osteoporosis.
Topics: Arthritis, Rheumatoid; Arthroplasty; Humans; Osteoporosis; Penicillamine; Postoperative Care; Skinfo | 1977 |
[Study of optimal posology of penicillamine in the treatment of common rheumatoid polyarthritis (apropos of a personal series of 200 cases)].
Topics: Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Penicillamine | 1977 |
Penicillamine: its place in rheumatology.
Topics: Arthritis, Rheumatoid; Humans; Penicillamine | 1978 |
Toxicity of D-penicillamine in rheumatoid arthritis. A report of 63 patients including two with aplastic anemia and one with the nephrotic syndrome.
Topics: Adult; Aged; Anemia, Aplastic; Arthritis, Rheumatoid; Blood Platelets; Female; Humans; Leukocytes; M | 1978 |
Determination of penicillamine in blood and urine by high performance liquid chromatography.
Topics: Arthritis, Rheumatoid; Chromatography, High Pressure Liquid; Drug Stability; Humans; Oxidation-Reduc | 1978 |
How to treat rheumatoid arthritis with penicillamine.
Topics: Arthritis, Rheumatoid; Female; Humans; Middle Aged; Penicillamine | 1978 |
Penicillamine: its place in rheumatology.
Topics: Arthritis, Rheumatoid; Humans; Penicillamine | 1978 |
[Myasthenic syndrome during penicillamine treatment (author's transl)].
Topics: Adult; Arthritis, Rheumatoid; Cholinesterase Inhibitors; Electrophysiology; Humans; Male; Middle Age | 1978 |
Neutrophil chemotaxis in rheumatoid arthritis. Effect of D-penicillamine, gold salts, and levamisole.
Topics: Adult; Aged; Arthritis, Rheumatoid; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Female; | 1978 |
Cholestatic jaundice caused by D-penicillamine.
Topics: Arthritis, Rheumatoid; Cholestasis; Humans; Liver; Male; Middle Aged; Penicillamine | 1978 |
Effect of penicillamine after gold treatment.
Topics: Adult; Arthritis, Rheumatoid; Drug Interactions; Female; Gold; Humans; Penicillamine | 1978 |
[Therapy of rheumatoid arthritis using D-penicillamine].
Topics: Arthritis, Rheumatoid; Humans; Penicillamine | 1978 |
[Our experience in the treatment of rheumatoid polyarthritis with D-penicillamine].
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Penicillamine | 1978 |
D-penicillamine and zinc.
Topics: Arthritis, Rheumatoid; Humans; Penicillamine; Zinc | 1978 |
Towards safer penicillamine prescribing.
Topics: Arthritis, Rheumatoid; Humans; Penicillamine; Safety | 1978 |
[Our experience with D penicillamine in the treatment of rheumatoid polyarthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Drug Evaluation; Humans; Middle Aged; Penicillamine | 1978 |
[The failures of D penicillamine].
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Drug Evaluation; Female; Humans; Male; Middle Aged; | 1978 |
[Myasthenic reactions during penicillin therapy].
Topics: Arthritis, Rheumatoid; Female; Humans; Middle Aged; Myasthenia Gravis; Penicillamine | 1978 |
[D-penicillamine and steroids in the treatment of rheumatoid arthritis].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Arthritis, Rheumatoid; Drug Therapy, Combination; | 1978 |
Rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Bed Rest; Gold; H | 1978 |
Is penicillamine therapy in rheumatoid arthritis influenced by previous treatment with gold?
Topics: Arthritis, Rheumatoid; Gold; Humans; Penicillamine | 1978 |
[Initiation of myasthentic reactions by means of d-penicillamine (author's transl1].
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Cholinesterase Inhibitors; Female; Humans; Male; Mid | 1978 |
[Correlation between serum copper level and enzymatic activity as well as the level of protein in ceruloplasmin].
Topics: Arthritis, Rheumatoid; Carrier Proteins; Ceruloplasmin; Copper; Humans; Penicillamine | 1978 |
Cutaneous lupus induced by penicillamine.
Topics: Arthritis, Rheumatoid; Female; Humans; Lupus Vulgaris; Middle Aged; Penicillamine | 1978 |
Taste dysfunction and changes in zinc and copper metabolism during penicillamine therapy for generalized scleroderma.
Topics: Adult; Aged; Arthritis, Rheumatoid; Copper; Female; Humans; Male; Metabolic Diseases; Middle Aged; P | 1978 |
Toxicity of penicillamine. A serious limitation to therapy in rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Female; Gastrointestinal Diseases; H | 1978 |
[D-penicillamine in the treatment of early stages of rheumatoid arthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Humans; Middle Aged; Penicillamine | 1978 |
[Effect of penicillamine on the blood serum copper level and acute phase tests in patients with rheumatoid arthritis].
Topics: Acute Disease; Adolescent; Adult; Aged; Arthritis, Rheumatoid; Blood Sedimentation; Copper; Female; | 1978 |
Penicillamine-induced polymyositis-dermatomyositis.
Topics: Action Potentials; Arthritis, Rheumatoid; Dermatomyositis; Female; Humans; Middle Aged; Muscle Contr | 1978 |
[Immunosuppressive treatment of rheumatoid arthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Azathioprine; Drug Therapy, Combination; Follow-Up Studies; Huma | 1978 |
[Evaluation and the future of new antirheumatic drugs].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Drug Evaluation; Gold; Humans; Imipramine; Penicill | 1978 |
[Scintigraphic studies of the course of primary chronic polyarthritis after basic therapy with gold salts and with D-penicillamine].
Topics: Adult; Aged; Arthritis; Arthritis, Rheumatoid; Female; Gold; Humans; Male; Middle Aged; Penicillamin | 1978 |
Miliary pulmonary infiltrates and penicillamine.
Topics: Arthritis, Rheumatoid; Female; Humans; Lung Diseases; Middle Aged; Penicillamine; Radiography | 1978 |
Penicillamine and previous treatment with gold.
Topics: Arthritis, Rheumatoid; Gold; Humans; Penicillamine | 1978 |
Rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antimalarials; Arthr | 1978 |
D-penicillamine and lupus erythematosuslike syndrome.
Topics: Adult; Arthritis, Rheumatoid; Female; Humans; Lupus Erythematosus, Systemic; Penicillamine; Syndrome | 1978 |
Treatment of rheumatoid arthritis with D-penicillamine.
Topics: Arthritis, Rheumatoid; Humans; Penicillamine | 1978 |
[Treatment of rheumatoid arthritis and other connective tissue diseases in Japan (author's transl)].
Topics: Arthritis, Rheumatoid; Collagen Diseases; Humans; Japan; Penicillamine; Surveys and Questionnaires | 1978 |
Modern management of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Humans; Occupational Therapy; Penicillamine; Physical Therapy Modalities | 1978 |
[Myasthenia gravis as a complication of D-penicillamine treatment in rheumatoid arthritis].
Topics: Arthritis, Rheumatoid; Female; Humans; Middle Aged; Myasthenia Gravis; Penicillamine | 1978 |
[The serum copper level and the therapeutic effect of D-penicylamine in patients with rheumatoid arthritis (author's transl)].
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Copper; Female; Humans; Male; Middle Aged; Penicilla | 1978 |
[Myasthenia syndrome after peroral treatment with penicillamine].
Topics: Arthritis, Rheumatoid; Blepharoptosis; Female; Humans; Middle Aged; Myasthenia Gravis; Penicillamine | 1978 |
[Myasthenic syndrome following oral treatment with penicillamine].
Topics: Arthritis, Rheumatoid; Blepharoptosis; Deglutition Disorders; Diplopia; Female; Humans; Middle Aged; | 1978 |
[On the mode of action of antirheumatic drugs (author's transl)].
Topics: Antibiotics, Antineoplastic; Arthritis, Rheumatoid; Azathioprine; Chloroquine; Gold; Gold Sodium Thi | 1976 |
[Medical treatment of rheumatoid arthritis].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Chloroquine | 1976 |
Neonatal abnormalities associated with D-penicillamine treatment during pregnancy.
Topics: Abnormalities, Drug-Induced; Adult; Arthritis, Rheumatoid; Female; Fetus; Humans; Infant, Newborn; P | 1977 |
[Clinical experiences with d-penicillamine in rheumatoid arthritis (author's transl)].
Topics: Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Nausea; Penicillamine; Proteinuria; Skin M | 1977 |
Dermatomyositis complicating penicillamine treatment.
Topics: Arthritis, Rheumatoid; Dermatomyositis; Female; Humans; Middle Aged; Penicillamine | 1977 |
[The effect of treatment on circulating immune complexes in rheumatoid arthritis (author's transl)].
Topics: Antigen-Antibody Complex; Arthritis, Rheumatoid; Gold; Humans; Immunosuppressive Agents; Levamisole; | 1977 |
D-penicillamine in the treatment of rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; Drug Tolerance; Female; Humans; Male; Middle Aged; Penicillamine | 1977 |
Pemphigus erythematosus-like rash in a patient on penicillamine.
Topics: Arthritis, Rheumatoid; Erythema; Female; Humans; Middle Aged; Pemphigus; Penicillamine | 1977 |
Penicillamine in the treatment of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Gold; Humans; Penicillamine | 1977 |
[Effect of D-penicillamine on rheumatoid factor, necrotizing factor and vascular permeability factor].
Topics: Arthritis, Rheumatoid; Capillary Permeability; Humans; Immunoglobulin M; In Vitro Techniques; Mercap | 1977 |
[D-pencillamine therapy in rheumatoid arthritis].
Topics: Adult; Arthritis, Rheumatoid; Drug Evaluation; Female; Humans; Male; Middle Aged; Penicillamine | 1977 |
[Drug therapy for chronic polyarthritis].
Topics: Arthritis, Rheumatoid; Chloroquine; Gold; Humans; Immunosuppressive Agents; Penicillamine | 1977 |
D-Penicillamine-induced myasthenia gravis in rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Female; Humans; Myasthenia Gravis; Penicillamine | 1977 |
Ulceration of the cornea in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Azathioprine; Corneal Ulcer; Female; Humans; Male; Penicillamine | 1977 |
Effect of penicillamine on complement in vitro and in vivo.
Topics: Animals; Antigen-Antibody Complex; Arthritis, Rheumatoid; Complement Fixation Tests; Complement Inac | 1977 |
The treatment of rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Child; Chloroquine; Female; Gold; Humans; Hydroxychl | 1977 |
[Actual results of the rheumatoid polyarthritis therapy with immuno-suppressive drugs: d-penicillamine and cytostatics (author's transl)].
Topics: Arthritis, Rheumatoid; Humans; Immunosuppressive Agents; Penicillamine | 1977 |
[Laboratory findings in patients with rheumatoid arthritis during D-penicillamine- and goldtherapy (author's transl)].
Topics: Arthritis, Rheumatoid; Blood Chemical Analysis; Gold; Humans; Penicillamine | 1977 |
[Effects and adverse effects in D-penicillamine therapy].
Topics: Arthritis, Rheumatoid; Blood Coagulation Disorders; Female; Hepatolenticular Degeneration; Humans; M | 1977 |
Penicillamine-associated myasthenia gravis, antiacetylcholine receptor and antistriational antibodies.
Topics: Acetylcholine; Adult; Aged; Antibodies; Arthritis, Rheumatoid; Female; Humans; Immunoglobulin G; Mal | 1977 |
Ambivalent role of copper in inflammatory disorders.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Copper; Humans; Inflammation; Irritants; P | 1976 |
Immunopathology of penicillamine-induced glomerular disease.
Topics: Arthritis, Rheumatoid; Biopsy, Needle; Female; Humans; Kidney; Kidney Glomerulus; Male; Middle Aged; | 1976 |
[Ocular myasthenia caused by D-penicillamine (author's transl)].
Topics: Adult; Arthritis, Rheumatoid; Eye Diseases; Female; Humans; Male; Middle Aged; Myasthenia Gravis; Pe | 1976 |
Symposium on specific therapy for rheumatoid arthritis: specific therapy in new conventional animal models.
Topics: Animals; Arthritis, Rheumatoid; Clotrimazole; Dexamethasone; Disease Models, Animal; Gold; Indometha | 1976 |
Specific therapy for rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Chloroquine; Gold; Humans; Levamisole; Penicillamine | 1976 |
Application of visual-analogue scales to the measurement of functional capacity.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Humans; Methods; Pain; Penicillamine; Time Factors | 1976 |
Application of visual-analogue scales to the measurement of functional capacity.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Humans; Methods; Pain; Penicillamine; Time Factors | 1976 |
Application of visual-analogue scales to the measurement of functional capacity.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Humans; Methods; Pain; Penicillamine; Time Factors | 1976 |
Application of visual-analogue scales to the measurement of functional capacity.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Humans; Methods; Pain; Penicillamine; Time Factors | 1976 |
Development of models for penicillamine-like drugs.
Topics: Animals; Arthritis, Rheumatoid; Disease Models, Animal; Levamisole; Penicillamine; Pertussis Vaccine | 1976 |
D-Penicillamine does not have a lathyritic effect on the rheumatoid synovium.
Topics: Arthritis, Rheumatoid; Collagen; Humans; Penicillamine; Synovial Membrane | 1976 |
Cyclophosphamide, gold and penicillamine--disease-modifying drugs in rheumatoid arthritis--tailored dosage and ultimate success.
Topics: Arthritis, Rheumatoid; Cyclophosphamide; Gold; Humans; Penicillamine; Time Factors | 1976 |
The pathogenesis of rheumatoid arthritis and the mode of action of various drugs: an hypothesis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Gold; Humans; Penicillamine | 1976 |
[Penicillamine-induced myasthenia in chronic rheumatoid arthritis (author's transl)].
Topics: Adult; Aged; Arthritis, Rheumatoid; Cholinesterase Inhibitors; Chronic Disease; Female; Humans; Midd | 1976 |
[D-penicillamine].
Topics: Arthritis, Rheumatoid; Humans; Penicillamine; Thrombocytopenia | 1976 |
[Experiences in the treatment of chronic polyarthritis using D-penicillamine (proceedings)].
Topics: Adult; Arthritis, Rheumatoid; Blood Sedimentation; Copper; Female; Glucocorticoids; Humans; Male; Mi | 1976 |
D-penicillamine-induced polymyositis in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Bundle-Branch Block; Electromyography; Female; Humans; Middle Aged; Myositis; | 1976 |
Treatment of rheumatoid polyarthritis with synthetic D-penicillamine 'Ho-Bay 950' [Proceedings].
Topics: Arthritis, Rheumatoid; Drug Evaluation; Humans; Penicillamine | 1976 |
[Glomerulopathy due to D-penicillamine--clinical findings and renal biopsy].
Topics: Adult; Aged; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Female; Glomerulonephritis; Hu | 1976 |
[Experiences in the treatment of chronic polyarthritis using D-penicillamine].
Topics: Adult; Arthritis, Rheumatoid; Chronic Disease; Female; Humans; Male; Penicillamine | 1976 |
D-Penicillamine.
Topics: Adult; Arthritis, Rheumatoid; Humans; Penicillamine; Pulmonary Fibrosis | 1976 |
[D-penicillamine and glomerulonephritis].
Topics: Adult; Arthritis, Rheumatoid; Female; Glomerulonephritis; Humans; Kidney; Male; Middle Aged; Penicil | 1976 |
[Current treatment of rheumatoid arthritis].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antidepressive Agents; Arthritis, Rheumatoid; Gol | 1976 |
Penicillamine nephropathy in rheumatoid arthritis. A clinical, pathological and immunological study.
Topics: Adult; Antigen-Antibody Complex; Arthritis, Rheumatoid; Female; Humans; Kidney; Kidney Diseases; Kid | 1976 |
[Myasthenia gravis and autoimmune thyroiditis during the treatment of rheumatoid polyarthritis withD-penicillamine. Anatomoclinical study of 1 case].
Topics: Arthritis, Rheumatoid; Autoantibodies; Autoimmune Diseases; Female; Humans; Middle Aged; Myasthenia | 1976 |
Penicillamine in rheumatoid arthritis: comparison of two dose schedules [proceedings].
Topics: Adult; Aged; Arthritis, Rheumatoid; Drug Administration Schedule; Humans; Middle Aged; Penicillamine | 1976 |
Pemphigus foliaceus induced by penicillamine.
Topics: Aged; Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Pemphigus; Penicillamine | 1976 |
Penicillamine in rheumatoid arthritis. Connective tissue changes and alterations in serum copper and phase reactants in relation to clinical improvement.
Topics: Adult; Aged; Arthritis, Rheumatoid; Collagen; Complement C3; Complement C4; Connective Tissue; Coppe | 1976 |
Penicillamine treatment of rheumatoid arthritis: effect on immune complexes.
Topics: Antigen-Antibody Complex; Arthritis, Rheumatoid; Chemical Phenomena; Chemistry; Humans; Immunoglobul | 1975 |
[Clinical and prognostic significance of antinuclear factors during D-penicillamine treatment (author's transl)].
Topics: Adult; Antibodies, Antinuclear; Arthritis, Rheumatoid; Humans; Kidney Diseases; Male; Middle Aged; P | 1975 |
Sensible prescribing. The treatment of rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Arthroplast | 1975 |
[Immunosuppressive treatment of rheumatologic diseases].
Topics: Arthritis; Arthritis, Rheumatoid; Drug Evaluation; Female; Humans; Immunity, Cellular; Immunosuppres | 1976 |
[Autoimmune phenomena in D-penicillamine therapy].
Topics: Antibodies, Antinuclear; Antibody Formation; Antigen-Antibody Reactions; Arthritis, Rheumatoid; Exan | 1975 |
New approaches to anti-rheumatic drugs.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Humans; Pe | 1976 |
Autoantibodies in D-penicillamine treated rheumatoid arthritis.
Topics: Adult; Aged; Antibodies, Antinuclear; Arthritis, Rheumatoid; Autoantibodies; DNA; Female; Humans; Lu | 1976 |
Effect of penicillamine therapy on circulating immune complexes in rheumatoid arthritis.
Topics: Adult; Aged; Antibodies, Antinuclear; Antigen-Antibody Complex; Arthritis, Rheumatoid; Blood Sedimen | 1975 |
Bone and joint diseases in the elderly.
Topics: Activities of Daily Living; Adrenal Cortex Hormones; Age Factors; Aged; Anti-Inflammatory Agents; Ar | 1976 |
Myasthenia gravis associated with penicillamine treatment for rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Cholinesterase Inhibitors; Female; Humans; Male; Middle Aged; Myasthen | 1975 |
Nursing care of outpatients taking penicillamine as a trial drug in the treatment of rheumatoid arthritis.
Topics: Ambulatory Care; Arthritis, Rheumatoid; Humans; Penicillamine | 1975 |
[Penicillamine in the treatment of rheumatoid arthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Drug Evaluation; Drug Hypersensitivity; Humans; Middle Aged; Pen | 1975 |
Editorial: Penicillamine: more lessons from experience.
Topics: Arthritis, Rheumatoid; Blood Cell Count; Drug Hypersensitivity; Humans; Penicillamine; Proteinuria; | 1975 |
Proceedings: Antiarthritic properties of cystein derivatives in comparison with D-penicillamin in rats.
Topics: Animals; Arthritis, Rheumatoid; Cysteine; Elasticity; Female; Freund's Adjuvant; Penicillamine; Rats | 1975 |
Rheumatoid arthritis, vasculitis and paroxysmal hypertension.
Topics: Adrenal Gland Neoplasms; Aged; Arteritis; Arthritis, Rheumatoid; Diagnosis, Differential; Gangrene; | 1975 |
[Moschcowitz's syndrome following D-penicillamine medication].
Topics: Aged; Anemia, Hemolytic; Arthritis, Rheumatoid; Female; Humans; Intracranial Embolism and Thrombosis | 1975 |
[Severe side-effects of treatment with D-penicillamine (author's transl)].
Topics: Acute Disease; Adult; Arthritis, Rheumatoid; Drug Hypersensitivity; Female; Humans; Male; Middle Age | 1975 |
[Penicillamine in rheumatoid arthritis].
Topics: Arthritis, Rheumatoid; Humans; Penicillamine | 1975 |
[Early recognition of adverse effects, especially of kidney lesions, in patients with progressive chronic polyarthritis under D-Penicillamine therapy].
Topics: Arthritis, Rheumatoid; Chronic Disease; Humans; Kidney Diseases; Penicillamine; Proteinuria; Time Fa | 1975 |
Urinary copper excretion in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Ceruloplasmin; Contraceptives, Oral, Hormonal; Copper; Estrogens | 1975 |
[Critical evaluation of rheumatism therapy. Basic drugs].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Azathioprine; Chloroquine; Evaluation Studies as To | 1975 |
[Pharmacotherapy of rheumatic diseases].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chronic Disease; Gold; Hum | 1975 |
[Cure of scleromalacia perforans manifesting in the course of rheumatoid arthritis with d-penicillamine and fascia lata-autograft (author's transl)].
Topics: Aged; Arthritis, Rheumatoid; Eye Diseases; Fascia; Fascia Lata; Female; Humans; Penicillamine; Predn | 1975 |
[Letter: Myasthenia and autoimmune thyroiditis during rheumatoid polyarthritis treated by D-penicillamine].
Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Female; Humans; Middle Aged; Myasthenia Gravis; Penicill | 1975 |
[D-penicillamine in rheumatoid arthritis (author's transl)].
Topics: Arthritis, Rheumatoid; Humans; Penicillamine | 1975 |
[Pemphigus induced by D-penicillamine in rheumatoid arthritis. Study of 5 cases and systematic study of anti-intercellular substance antibodies of the skin in the course of treatment].
Topics: Adult; Arthritis, Rheumatoid; Autoantibodies; Autoimmune Diseases; Female; Humans; Pemphigus; Penici | 1975 |
[Mechanism of action and clinical effectiveness of D-penicillamine in infectious nonspecific (rheumatoid) polyarthritis].
Topics: Arthritis, Rheumatoid; Drug Evaluation; Female; Humans; Male; Penicillamine | 1975 |
[Treatment of rheumatoid arthritis with kuprenyl (D-penicillamine)].
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Penicillamine | 1975 |
[The drug spectrum in rheumatoid arthritis therapy].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chloroquine; Cortisone; Gold; Humans; Immunosuppres | 1975 |
[The effect of D-penicillamine on the course of chronic polyarthritis].
Topics: Arthritis, Rheumatoid; Humans; Immunosuppressive Agents; Penicillamine | 1975 |
[Differential indications in rheumatism therapy on the basis of well-known drug side effects].
Topics: Arthritis, Rheumatoid; Azathioprine; Chloroquine; Glucocorticoids; Gold; Humans; Lupus Erythematosus | 1975 |
[D-penicillamine in the treatment of rheumatoid arthritis: preliminary note].
Topics: Arthritis, Rheumatoid; Drug Evaluation; Female; Humans; Male; Penicillamine | 1975 |
Letter: Goodpasture syndrome and D-penicillamine.
Topics: Anti-Glomerular Basement Membrane Disease; Arthritis, Rheumatoid; Humans; Male; Middle Aged; Penicil | 1976 |
[Intrahepatic cholestasis following treatment with D-penicillamine and indomethacin].
Topics: Adult; Arthritis, Rheumatoid; Cholestasis; Drug Therapy, Combination; Female; Humans; Indomethacin; | 1976 |
[Penicillamine on the decline?].
Topics: Arthritis, Rheumatoid; Humans; Penicillamine | 1976 |
[Effect of d-penicilamine treatment on desmofibrinogenesis disorders in patients with rheumatoid arthritis].
Topics: Adult; Arthritis, Rheumatoid; Blood Coagulation; Fibrin; Humans; Middle Aged; Penicillamine | 1976 |
[Penicillamine D in primary chronic polyarthritis. A long-term study].
Topics: Adult; Arthritis, Rheumatoid; Follow-Up Studies; Humans; Middle Aged; Penicillamine | 1976 |
[Penicillamine nephropathy].
Topics: Arthritis, Rheumatoid; Diagnosis, Differential; Humans; Immunoglobulin G; Nephrosis; Nephrotic Syndr | 1976 |
Studies on D-penicillamine metabolism in cystinuria and rheumatoid arthritis: isolation of S-methyl-D-penicillamine.
Topics: Arthritis, Rheumatoid; Cystinuria; Feces; Hepatolenticular Degeneration; Humans; Oxidation-Reduction | 1976 |
Objective measurement of rheumatoid arthritis using technetium index.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Drug Evaluation; Humans; Penicillamine; Technetium | 1976 |
Diffuse alveolitis as complication of penicillamine treatment for rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Female; Humans; Lung Diseases; Middle Aged; Penicillamine | 1976 |
[Proteinuria in immunopathological diseases during long-term penicillamine therapy (author's transl)].
Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Humans; Penicillamine; Proteinuria; Scleroderma, Systemi | 1976 |
D-penicillamine and rheumatoid factor.
Topics: alpha 1-Antitrypsin; Antigen-Antibody Complex; Arthritis, Rheumatoid; Humans; Immunoglobulin A; Peni | 1992 |
Longterm drug therapy for rheumatoid arthritis in seven rheumatology private practices: II. Second line drugs and prednisone.
Topics: Age Factors; Arthritis, Rheumatoid; Azathioprine; Drug Therapy, Combination; Gold; Humans; Hydroxych | 1992 |
D-penicillamine therapy associated with rapidly progressive glomerulonephritis.
Topics: Arthritis, Rheumatoid; Female; Glomerulonephritis; Hemoptysis; Humans; Methylprednisolone; Middle Ag | 1992 |
Long-term second-line treatment: a prospective drug survival study.
Topics: Arthritis, Rheumatoid; Aurothioglucose; Humans; Hydroxychloroquine; Penicillamine; Prospective Studi | 1992 |
Variations among rheumatologists in prescribing and monitoring of disease modifying antirheumatoid drugs.
Topics: Antimalarials; Arthritis, Rheumatoid; Drug Administration Schedule; Drug Monitoring; Drug Prescripti | 1992 |
Rheumatoid arthritis: an association with pemphigus foliaceous.
Topics: Adult; Arthritis, Rheumatoid; Female; HLA-DR4 Antigen; Humans; Immunoglobulin G; Male; Middle Aged; | 1992 |
The effect of second-line antirheumatic drugs on interleukin-8 mRNA synthesis and protein secretion in human endothelial cells.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Endothelium, Vascular; Gene Expression; Gold Sodium | 1992 |
Impaired suppressor cell activity due to surface sulphydryl oxidation in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Concanavalin A; Humans; Immunoglobul | 1992 |
Recurrent episodes of pseudoseptic arthritis in rheumatoid arthritis: response to D-penicillamine and methotrexate.
Topics: Arthritis, Infectious; Arthritis, Rheumatoid; Female; Humans; Methotrexate; Middle Aged; Penicillami | 1992 |
Isolation of the first crystalline D-penicillamine complex of iron and some remarks on relevant aspects of metal-chelating drugs as well as metabolism disorders.
Topics: Arthritis, Rheumatoid; Chelating Agents; Drug Design; Humans; Iron; Models, Molecular; Molecular Con | 1992 |
A longitudinal study of pulmonary function in patients with rheumatoid arthritis treated with gold and D-penicillamine.
Topics: Arthritis, Rheumatoid; Azathioprine; Female; Gold; Humans; Longitudinal Studies; Lung; Male; Middle | 1992 |
Frequent induction of insulin autoantibodies by D-penicillamine in patients with rheumatoid arthritis.
Topics: Adult; Aged; Aged, 80 and over; Antibody Formation; Arthritis, Rheumatoid; Autoantibodies; Female; H | 1992 |
Monitoring of patients with rheumatoid arthritis in longterm administration of D-penicillamine.
Topics: Aged; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Pe | 1992 |
Drug therapy in the rheumatic diseases.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Gold; Huma | 1992 |
Stimulation single fiber EMG study in patients receiving a long-term D-penicillamine treatment for rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Electromyography; Female; Humans; Male; Middle Aged; Neuromuscul | 1992 |
[Progress on diagnosis and therapy of kidney diseases complicated with rheumatoid arthritis and Sjogren's syndrome].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Gold; Humans; Kidney Diseases; Penic | 1992 |
HLA system and penicillamine induced pemphigus in nine cases of rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; HLA Antigens; HLA-A Antigens; HLA-B Antigens; HLA-DR Ant | 1992 |
Effect of penicillamine on the titre of the rheumatoid factor: a historical perspective.
Topics: Arthritis, Rheumatoid; History, 20th Century; Humans; Penicillamine; Rheumatoid Factor | 1992 |
Clinical analysis by 1H spin-echo NMR. 2. Oxidation of intracellular glutathione as a consequence of penicillamine therapy in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Erythrocytes; Female; Glutathione; Humans; Magnetic Resonance Spectroscopy; M | 1992 |
Management of proteinuria secondary to penicillamine therapy in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Edema; Humans; Penicillamine; Proteinuria | 1992 |
A controlled study of lymphocyte subsets in rheumatoid arthritis.
Topics: Aging; Antineoplastic Agents; Arthritis, Rheumatoid; Gold; Humans; Hydroxychloroquine; Lymphocyte Su | 1992 |
Drugs for rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, | 1991 |
[Clinicopathological study of nephropathy in patients with rheumatoid arthritis].
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; F | 1991 |
[Rheumatoid arthritis developing into systemic lupus erythematosus during long-term treatment with penicillamine and sulfasalazine].
Topics: Adult; Arthritis, Rheumatoid; Female; Humans; Lupus Erythematosus, Systemic; Penicillamine; Sulfasal | 1991 |
[Rheumatoid arthritis. Diagnosis, anatomopathology, evolution, prognosis, treatment].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Antirheumatic Agent | 1991 |
The gold standard in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Gold; Humans; Penicillamine; Prognosis; Sulfasalazine | 1991 |
Nonsteroidal peptic damage in rheumatoid patients receiving second-line drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Drug Therapy, Combination; Endoscopy | 1991 |
[Bottom-line treatments in rheumatoid arthritis].
Topics: Antimalarials; Antirheumatic Agents; Arthritis, Rheumatoid; Humans; Immunosuppressive Agents; Organo | 1991 |
Disease-modifying anti-rheumatic drug therapy. An expensive therapy despite inexpensive drugs.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; Costs and Cost Analysis; Fema | 1990 |
Complement C4 null alleles as a marker of gold or D-penicillamine toxicity in the treatment of rheumatoid arthritis.
Topics: Alleles; Amino Acid Sequence; Arthritis, Rheumatoid; Complement C4; Gene Frequency; Genetic Markers; | 1992 |
Mortality predictors among 263 patients with rheumatoid arthritis.
Topics: Adult; Age Factors; Aged; Arthritis, Rheumatoid; Cohort Studies; Female; Health Status Indicators; H | 1991 |
Relationship between severity of rheumatoid arthritis and serum alpha 1-antitrypsin.
Topics: Adult; Aged; Aged, 80 and over; alpha 1-Antitrypsin; Arthritis, Rheumatoid; Female; Gold; Humans; Ma | 1991 |
Pathogenesis of peptic ulcer in rheumatoid arthritis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Castor Oil; Female; Gastric M | 1991 |
Rheumatoid nodules do not predict response to treatment with slow-acting anti-rheumatic drugs.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Cohort Studies; Female; Forecasting; Humans; Male; | 1991 |
D-penicillamine toxicity in Greek patients with rheumatoid arthritis: anti-Ro(SSA) antibodies and cryoglobulinemia are predictive factors.
Topics: Antibodies, Antinuclear; Arthritis, Rheumatoid; Cryoglobulinemia; Drug Eruptions; Female; Fluorescen | 1991 |
Low back pain associated with penicillamine.
Topics: Aged; Arthritis, Rheumatoid; Back Pain; Drug Hypersensitivity; Female; Humans; Penicillamine | 1991 |
Complete reversal of rheumatoid nodulosis.
Topics: Arthritis, Rheumatoid; Female; Humans; Hydroxychloroquine; Middle Aged; Penicillamine; Pyridoxine; R | 1991 |
Penicillamine induced lupus-like syndrome in a patient with classical rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Female; Humans; Lupus Erythematosus, Systemic; Penicillamine | 1991 |
Penicillamine induced myositis: correlation between urinary zinc excretion and serum creatine.
Topics: Adult; Arthritis, Rheumatoid; Creatine; Female; Humans; Myositis; Penicillamine; Zinc | 1991 |
Pure red cell aplasia caused by D-penicillamine treatment of rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Female; Humans; Penicillamine; Prednisolone; Red-Cell Aplasia, Pure | 1991 |
D-penicillamine-induced lupus erythematosus.
Topics: Arthritis, Rheumatoid; Humans; Lupus Erythematosus, Systemic; Penicillamine | 1991 |
Can we develop simple response criteria for slow acting antirheumatic drugs?
Topics: Arthritis, Rheumatoid; Cohort Studies; Female; Humans; Male; Middle Aged; Penicillamine; Prospective | 1990 |
[New principle of the treatment of rheumatoid arthritis: combined basic therapy].
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Delayed-Action Preparations; Dru | 1990 |
[Interstitial lung disease in rheumatoid arthritis].
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Bronchiolitis Obliterans; Bronchoalveolar Lavage | 1990 |
Assessing combination therapy in rheumatoid arthritis: treatment with sulphasalazine and penicillamine.
Topics: Arthritis, Rheumatoid; Drug Therapy, Combination; Female; Humans; Male; Penicillamine; Prospective S | 1990 |
Termination of slow acting antirheumatic therapy in rheumatoid arthritis: a 14-year prospective evaluation of 1017 consecutive starts.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, | 1990 |
Long-term radiographic progression in treated rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Humans; Hydroxychloroquine; Penicillamine; Radiography; Sulfasalazine; Time F | 1990 |
[Maintenance treatments of rheumatoid arthritis].
Topics: Antimalarials; Antineoplastic Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Humans; Methotrex | 1990 |
Clinical and laboratory effects of prolonged therapy with sulfasalazine, gold or penicillamine: the effects of disease duration on treatment response.
Topics: Arthritis, Rheumatoid; Blood Sedimentation; C-Reactive Protein; Female; Gold; Humans; Male; Penicill | 1990 |
Autoantibodies in D-penicillamine-induced myasthenia gravis: a comparison with idiopathic myasthenia and rheumatoid arthritis.
Topics: Adult; Aged; Antibodies, Antinuclear; Arthritis, Rheumatoid; Autoantibodies; Enzyme-Linked Immunosor | 1991 |
Cutaneous problems with drug therapy in rheumatoid arthritis.
Topics: Acute Disease; Adult; Arthritis, Rheumatoid; Dermatomyositis; Female; Humans; Penicillamine | 1991 |
[Side-effects of treatment of 74 rheumatoid polyarthritis with tiopronin].
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Drug Interactions; Female; Follow-Up Studies; | 1991 |
[Frequency and prognostic features of rheumatoid patients with remission-inducing agents--a comparison of different kinds of medication].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Female; Humans; Male; Middle | 1990 |
Is there a need to reclassify adult rheumatoid arthritis?
Topics: Arthritis, Rheumatoid; Female; Genes; Genetic Predisposition to Disease; Gold; HLA-DQ Antigens; HLA- | 1990 |
[New diagnostic standards in rheumatoid arthritis and recent trends in drug therapy].
Topics: Arthritis, Rheumatoid; Gold Sodium Thiomalate; Humans; Penicillamine; Prednisolone; Prognosis; Refer | 1990 |
In vitro effects of two gold compounds, and D-penicillamine on the production of interferon gamma.
Topics: Adult; Aged; Arthritis, Rheumatoid; Auranofin; Concanavalin A; Female; Gold Sodium Thiomalate; Human | 1990 |
[Cutaneous side effects induced by D-penicillamine in the treatment of rheumatoid arthritis].
Topics: Antibodies; Arthritis, Rheumatoid; Cell Nucleus; DNA; Drug Eruptions; Female; Humans; Middle Aged; P | 1990 |
[Long-term tolerability of tiopronin (Acadione) in the treatment of rheumatoid arthritis. Apropos of 140 personal cases].
Topics: Arthritis, Rheumatoid; Drug Eruptions; Drug Hypersensitivity; Female; Follow-Up Studies; Humans; Mal | 1990 |
Penicillamine-induced ocular myasthenia gravis in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Diplopia; Female; Humans; Middle Aged; Myasthenia Gravis; Ocular Motility Dis | 1990 |
Combination D-penicillamine and methotrexate therapy: proposal for early and aggressive treatment for rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Drug Therapy, Combination; Female; Humans; Methotrexate; Middle | 1990 |
Elastic fibre damage induced by low-dose D-penicillamine.
Topics: Adult; Aged; Arthritis, Rheumatoid; Drug Administration Schedule; Elastic Tissue; Female; Humans; Jo | 1990 |
Effects of D-penicillamine treatment on antioxidant enzymes in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Glutathione Peroxidase; Humans; Penicillamine; Superoxide Dismutase | 1990 |
[Methylprednisolone-pulse therapy in a patient with rheumatoid arthritis and diffuse interstitial pneumonia/pulmonary fibrosis].
Topics: Arthritis, Rheumatoid; Chronic Disease; Drug Therapy, Combination; Female; Humans; Infusions, Intrav | 1990 |
[The effect of D-penicillamine on the immunological indices of rheumatoid arthritis patients].
Topics: Antibody Formation; Arthritis, Rheumatoid; Capsules; Drug Evaluation; Female; Humans; Immunity, Cell | 1990 |
D-penicillamine and D-penicillamine-protein disulphide in plasma and synovial fluid of patients with rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Chromatography, High Pressure Liquid; Electrochemistry; Humans; | 1990 |
Penicillamin-induced neuropathy in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Demyelinating Diseases; Dose-Response Relationship, Drug; Evoked Potentials, | 1990 |
The relationship of sulfoxidation status to efficacy and toxicity of penicillamine in the treatment of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Carbocysteine; Humans; Penicillamine; Prospective Studies; Sulfoxides | 1990 |
[The healing of the bone erosions during therapy with gold preparations and D-penicillamine in rheumatoid arthritis patients].
Topics: Adult; Arthritis, Rheumatoid; Bone Regeneration; Dose-Response Relationship, Drug; Drug Therapy, Com | 1990 |
The relationship between the complex of immunoglobulin A and alpha-1-antitrypsin, its constituent components and the acute-phase response as measured by C-reactive protein in rheumatoid arthritis treated with gold or D-penicillamine.
Topics: Acute-Phase Proteins; alpha 1-Antitrypsin; Arthritis, Rheumatoid; C-Reactive Protein; Female; Gold S | 1987 |
Adult rheumatoid arthritis is associated with MC1, a new HLA-D encoded determinant.
Topics: Arthritis, Rheumatoid; Chromosome Mapping; Epitopes; Genetic Code; Gold; HLA-D Antigens; HLA-DR Anti | 1988 |
Fine antigenic specificities of antibodies in sera from patients with D-penicillamine-induced myasthenia gravis.
Topics: Adult; Aged; Aged, 80 and over; Antibody Formation; Arthritis, Rheumatoid; Binding, Competitive; Epi | 1988 |
Should one use second-line agents such as gold and D-penicillamine in a patient with active rheumatoid arthritis and asymptomatic microscopic haematuria for which no cause can be determined?
Topics: Arthritis, Rheumatoid; Gold Sodium Thiomalate; Hematuria; Humans; Penicillamine | 1989 |
Blood monocyte elastolytic activity enhanced by immune complex stimulation in patients with rheumatoid arthritis and normal controls. Effect of aurothiomalate or D-penicillamine.
Topics: Adult; Aged; Aged, 80 and over; Antigen-Antibody Complex; Arthritis, Rheumatoid; Cells, Cultured; El | 1989 |
Comparison of serum and synovial fluid concentrations of beta 2-microglobulin and C reactive protein in relation to clinical disease activity and synovial inflammation in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; beta 2-Microglobulin; C-Reactive Protein; Gold Sodium Thiomalate; Humans; Kne | 1989 |
Drugs for rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Azathioprin | 1989 |
Nail-changes induced by penicillamine.
Topics: Aged; Arthritis, Rheumatoid; Female; Humans; Nail Diseases; Penicillamine; Recurrence | 1989 |
Sulphasalazine in rheumatoid arthritis: haematological problems.
Topics: Arthritis, Rheumatoid; Hepatolenticular Degeneration; Humans; Penicillamine; Sulfasalazine | 1989 |
Rheumatoid arthritis and AIDS.
Topics: Acquired Immunodeficiency Syndrome; Arthritis, Rheumatoid; CD4-Positive T-Lymphocytes; Humans; Penic | 1989 |
Penicillamine-induced polymyositis with complete heart block.
Topics: Aged; Arthritis, Rheumatoid; Bundle-Branch Block; Electrocardiography; Heart Block; Humans; Male; My | 1989 |
Development of morphoea in rheumatoid arthritis treated with penicillamine.
Topics: Aged; Arthritis, Rheumatoid; Female; Humans; Penicillamine; Scleroderma, Localized | 1989 |
Penicillamine for interstitial lung disease in rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Mid | 1989 |
[Association of immunomodulators and HLA antigens in rheumatoid arthritis].
Topics: Adjuvants, Immunologic; Adult; Aged; Arthritis, Rheumatoid; Auranofin; Female; HLA Antigens; Humans; | 1989 |
Penicillamine-induced bullous pemphigoid with pemphigus-like antibodies.
Topics: Aged; Antibodies; Arthritis, Rheumatoid; Biopsy; Fluorescent Antibody Technique; Humans; Male; Pemph | 1989 |
[Evaluation of the usefulness of delayed-action preparations in the treatment of rheumatoid polyarthritis by analyzing the therapeutic maintenance dose].
Topics: Aged; Arthritis, Rheumatoid; Delayed-Action Preparations; Drug Evaluation; Female; Gold; Humans; Hyd | 1989 |
[Clinicopathological study of renal disorders in patients with rheumatoid arthritis].
Topics: Adolescent; Adult; Aged; Amyloidosis; Arthritis, Rheumatoid; Female; Gold; Humans; Kidney; Kidney Di | 1989 |
Fatal aplastic anaemia and liver toxicity caused by D-penicillamine treatment of rheumatoid arthritis.
Topics: Aged; Anemia, Aplastic; Arthritis, Rheumatoid; Female; Humans; Jaundice; Liver; Penicillamine | 1989 |
The natural course of gold and penicillamine nephropathy: a longterm study of 54 patients.
Topics: Adult; Arthritis, Rheumatoid; Creatinine; Female; Gold; Humans; Kidney; Kidney Diseases; Male; Middl | 1989 |
Induction of anticentromere antibody in patients receiving treatment with D-penicillamine.
Topics: Adult; Aged; Antibodies, Antinuclear; Arthritis, Rheumatoid; Autoantibodies; Autoimmune Diseases; Ce | 1989 |
D-penicillamine-induced oesophageal ulcers.
Topics: Arthritis, Rheumatoid; Esophageal Diseases; Female; Humans; Middle Aged; Penicillamine; Stomatitis, | 1989 |
Antirheumatic drugs and eicosanoid synthesis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cells, Cultured; Eicosanoic Acids; H | 1987 |
Serum amyloid A protein during the treatment of rheumatoid arthritis with second-line drugs.
Topics: Adult; Aged; Amyloid; Arthritis, Rheumatoid; Blood Sedimentation; C-Reactive Protein; Female; Gold S | 1985 |
Biochemical and clinical changes occurring during the treatment of rheumatoid arthritis with novel antirheumatoid drugs.
Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Viscosity; Captopril; Cysteine; Female; Humans; Male; Midd | 1985 |
False-positive Waaler-Rose test in IgA deficiency.
Topics: Antibodies, Anti-Idiotypic; Arthritis, Rheumatoid; Drug Combinations; Dysgammaglobulinemia; False Po | 1985 |
"Disease-modifying" drugs in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Chloroquine; Gold Sodium Thiomalate; Humans; Hydroxychloroquine; Immunosuppre | 1985 |
Overlap between non-steroidal anti-inflammatory drugs (NSAIDs) and anti-rheumatoid drugs (ARDs).
Topics: Aminosalicylic Acids; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Auranofin; Aurothioglucose; G | 1985 |
The effect of antirheumatic drugs on circulating immune complexes in rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents; Antigen-Antibody Complex; Arthritis, Rheumatoid; Blood Sedime | 1986 |
[Early detection of chronic polyarthritis. Does early treatment change the course?].
Topics: Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Diagnosis, Differential; Follow-Up S | 1986 |
Sulphasalazine alone or in combination with D-penicillamine in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Drug Therapy, Combination; Female; Humans; Male; Penicillamine; Sulfasalazine | 1987 |
Slow-acting anti-rheumatic drug therapy for rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Azathioprine; Cyclophosphamide; Gold; Humans; Hydroxychloroquine; Methotrexat | 1987 |
Long-term treatment of rheumatoid arthritis with sulphasalazine, gold, or penicillamine: a comparison using life-table methods.
Topics: Actuarial Analysis; Arthritis, Rheumatoid; Gold; Humans; Penicillamine; Sulfasalazine; Time Factors | 1987 |
Combination chemotherapy in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Drug Therapy, Combination; Humans; Penicillamine; Sulfasalazine | 1988 |
Rheumatoid arthritis: a pharmacologic overview.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Gold; Human | 1988 |
[The basic therapy of rheumatoid arthritis].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Drug Combinations; Drug Evaluation; Glucosamine; Go | 1988 |
Sulphasalazine in rheumatoid arthritis: combination therapy with D-penicillamine or sodium aurothiomalate.
Topics: Adult; Aged; Arthritis, Rheumatoid; Drug Administration Schedule; Drug Therapy, Combination; Female; | 1988 |
How reliable is ESR as a measure of disease activity in rheumatoid arthritis treated with hydroxychloroquine?
Topics: Arthritis, Rheumatoid; Blood Sedimentation; Blood Viscosity; Chloroquine; Drug Administration Schedu | 1988 |
Are slow-acting antirheumatic drugs being given earlier in rheumatoid arthritis?
Topics: Antimalarials; Arthritis, Rheumatoid; Autacoids; Azathioprine; Gold; Humans; Penicillamine; Time Fac | 1988 |
[Basic and clinical study on combined immunomodulator therapy in rheumatoid arthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Drug Therapy, Combination; Female; Gold Sodium Thiomalate; Human | 1988 |
[Treatment of rheumatoid arthritis: drugs which induce remission].
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Cyclophosphamide; Cyclosporins; Humans; M | 1988 |
The effect of continuing penicillamine and gold treatment on the course of penicillamine and gold nephropathy.
Topics: Aged; Arthritis, Rheumatoid; Biopsy; Creatinine; Female; Gold; Humans; Kidney; Kidney Diseases; Male | 1989 |
Type II collagen induced arthritis in rats: clinical and immunological studies.
Topics: Animals; Anti-Inflammatory Agents; Antigen-Antibody Complex; Arthritis, Rheumatoid; Autoimmune Disea | 1985 |
The toxicity of D-penicillamine in systemic sclerosis.
Topics: Arthritis, Rheumatoid; Digestive System Diseases; Dose-Response Relationship, Drug; Drug Eruptions; | 1986 |
European League against Rheumatism study of adverse reactions to D-penicillamine.
Topics: Aged; Arthritis, Rheumatoid; Drug Eruptions; Europe; Female; Gastrointestinal Diseases; Hematologic | 1986 |
[D-penicillamine and dermatopolymyositis. Value of the study of anti-JO 1 antibodies].
Topics: Antibodies; Arthritis, Rheumatoid; Dermatomyositis; Humans; Male; Middle Aged; Penicillamine | 1986 |
Elevated antigalactosyl antibody titers reflect renal injury after gold or D-penicillamine in rheumatoid arthritis.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; Antibody Formation; Antibody Specificit | 1986 |
Second-line drug treatment in rheumatoid arthritis associated with depressed autologous mixed lymphocyte reaction.
Topics: Arthritis; Arthritis, Rheumatoid; Gold Sodium Thiomalate; Humans; Lymphocyte Culture Test, Mixed; Pe | 1986 |
Penicillamine-induced bullous pemphigoid-like eruption.
Topics: Arthritis, Rheumatoid; Drug Eruptions; Humans; Male; Middle Aged; Pemphigoid, Bullous; Penicillamine | 1987 |
Toxicity to D-penicillamine in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Drug Eruptions; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; | 1987 |
[Syndrome of acute respiratory distress with a fatal development in a treatment with D-penicillamine].
Topics: Adult; Arthritis, Rheumatoid; Female; Humans; Penicillamine; Respiratory Distress Syndrome | 1988 |
[Pemphigus herpetiformis following D-penicillamine in a patient with HLA B8].
Topics: Arthritis, Rheumatoid; Dermatitis Herpetiformis; Drug Eruptions; HLA-B Antigens; HLA-B8 Antigen; Hum | 1988 |
Suggested mode of action of D-penicillamine as an immunosuppressive agent in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Ceruloplasmin; Copper; Copper Sulfate; DNA Replication; Humans; Hydrogen Pero | 1988 |
Antiarthritic drugs containing thiol groups scavenge hypochlorite and inhibit its formation by myeloperoxidase from human leukocytes. A therapeutic mechanism of these drugs in rheumatoid arthritis?
Topics: Amino Acids, Sulfur; Arthritis, Rheumatoid; Aurothioglucose; Cyclohexanones; Gold Sodium Thiomalate; | 1985 |
Studies of the effect of D-penicillamine and sodium aurothiomalate therapy on superoxide anion production by monocytes from patients with rheumatoid arthritis: evidence for in vivo stimulation of monocytes.
Topics: Arthritis, Rheumatoid; Gold Sodium Thiomalate; Humans; Monocytes; Penicillamine; Sulfhydryl Compound | 1986 |
Serum osteocalcin in rheumatoid arthritis and other inflammatory arthritides: relation between inflammatory activity and the effect of glucocorticoids and remission inducing drugs.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Arthritis; Arthritis, Rheumatoid; Azathioprine; Calcium-Bi | 1986 |
Assessment of kininases in rheumatic diseases and the effect of therapeutic agents.
Topics: Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Bradykini | 1987 |
[D-penicillamine--a retrospective view].
Topics: Arthritis, Rheumatoid; Europe; History, 20th Century; Humans; Penicillamine; United States | 1988 |
Massive eosinophilia in rheumatoid arthritis: report of four cases.
Topics: Adult; Aged; Arthritis, Rheumatoid; Eosinophilia; Female; Gold Sodium Thiomalate; Humans; Male; Midd | 1986 |
Peripheral blood T lymphocyte subsets in active rheumatoid arthritis--effects of different therapies on previously untreated patients.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Antigens, Differentiation, T-Lymphocyte; Antigens | 1986 |
An investigation of the action of disease modifying antirheumatic drugs on the rheumatoid synovial membrane: reduction in T lymphocyte subpopulations and HLA-DP and DQ antigen expression after gold or penicillamine therapy.
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Gold Sodium Thiomalate; HLA-D Antigens; HLA-DP Antigens; | 1987 |
Rheumatoid arthritis: a disturbance in copper homeostasis.
Topics: Arthritis, Rheumatoid; Copper; Gold Sodium Thiomalate; Homeostasis; Humans; Immunoglobulin G; Penici | 1987 |
Acetylator phenotypes in rheumatoid arthritis patients with or without adverse drug reactions to sodium-aurothiomalate or d-penicillamine.
Topics: Acetylation; Adult; Aged; Arthritis, Rheumatoid; Chromatography, High Pressure Liquid; Dapsone; Fema | 1987 |
ELISA assays for IgM and IgG rheumatoid factors: their clinical correlations during therapy with slow-acting anti-rheumatic drugs.
Topics: Arthritis, Rheumatoid; Enzyme-Linked Immunosorbent Assay; Gold Sodium Thiomalate; Humans; Immunoglob | 1987 |
Renal changes in patients with rheumatoid arthritis treated with sodium thiomalate and D-penicillamine.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Female; Gold Sodium Thiomalate; Humans; Male; Middle | 1987 |
Natural course of penicillamine nephropathy: a long term study of 33 patients.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Female; HLA Antigens; Humans; Kidney; Kidney Disease | 1988 |
Cyclosporine A in rheumatoid arthritis: results at 30 months.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antineoplastic; Arthr | 1988 |
Histocompatibility antigens in adult obliterative bronchiolitis with or without rheumatoid arthritis.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Bronchiolitis Obliterans; Disease Susceptibil | 1986 |
HLA-A,-B, and -DR antigens in relation to gold and D-penicillamine toxicity in Greek patients with RA.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Disease Susceptibility; Female; Gold Sodium Thiomala | 1986 |
Effects of antirheumatic drugs on renal function and eicosanoid excretion.
Topics: Arthritis, Rheumatoid; beta 2-Microglobulin; Dinoprostone; Gold Sodium Thiomalate; Humans; Kidney; P | 1987 |
Penicillamine nephropathy.
Topics: Arthritis, Rheumatoid; HLA-DR Antigens; Humans; Penicillamine | 1988 |
[Tiopronin in 69 cases of rheumatoid polyarthritis treated earlier with D-penicillamine].
Topics: Adult; Aged; Aged, 80 and over; Amino Acids, Sulfur; Arthritis, Rheumatoid; Drug Tolerance; Female; | 1988 |
Effects of long-term aurothiomalate and D-penicillamine treatments on renal function and urinary excretion of prostanoids in patients with rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Gold Sodium Thiomalate; Humans; Kidney Diseases; Kidney | 1988 |
Auranofin in rheumatoid arthritis: use in patients with side-effects or lack of effect to gold sodium thiomalate or gold thioglucose and/or D-penicillamine. A prospective one year investigation.
Topics: Arthritis, Rheumatoid; Auranofin; Aurothioglucose; Drug Resistance; Female; Gastrointestinal Disease | 1988 |
[The concept of basic therapy of chronic polyarthritis with D-penicillamine: clinical experiences over 10 years].
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Arthrography; Blood Sedimentation; C-Reactive Protei | 1988 |
Histidine analogues as potential novel antirheumatic agents.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Chelating Agents; Copper; Edetic Aci | 1986 |
Correlation of disease activity and drug therapy with the autologous mixed lymphocyte reaction in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Reactive; Arthritis, Rheumatoid; Female; Gold; Humans; Lymphocy | 1985 |
HLA antigens and adverse drug reactions to sodium aurothiomalate and D-penicillamine in patients with rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Diarrhea; Drug Eruptions; Female; Gold Sodium Thiomalate; Histoc | 1985 |
Penicillamine induced pemphigus--a report of 2 cases.
Topics: Aged; Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Pemphigus; Penicillamine | 1988 |
Progressive joint damage during penicillamine therapy for rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Arthrography; Blood Sedimentation; Female; Hemoglobins; Humans; | 1988 |
The use of a pharmacological indicator to investigate compliance in patients with a poor response to antirheumatic therapy.
Topics: Adult; Aged; Arthritis, Rheumatoid; Humans; Middle Aged; Monitoring, Physiologic; Patient Compliance | 1988 |
Penicillamine induced mammary hyperplasia: report of a case and review of the literature.
Topics: Adult; Arthritis, Rheumatoid; Breast; Danazol; Female; Humans; Hyperplasia; Penicillamine; Time Fact | 1988 |
[D-penicillamine in the treatment of rheumatism. Its value and side-effects. A discussion by international experts. Berlin].
Topics: Arthritis, Rheumatoid; Humans; Penicillamine | 1988 |
[Effectiveness and limits of D-penicillamine therapy].
Topics: Adult; Aged; Arthritis, Rheumatoid; Combined Modality Therapy; Dose-Response Relationship, Drug; Dru | 1988 |
[Basic therapy of chronic inflammatory joint diseases with D-penicillamine and disorders of wound healing in rheumatoid orthopedic interventions].
Topics: Arthritis, Rheumatoid; Combined Modality Therapy; Female; Hip Prosthesis; Humans; Joints; Male; Midd | 1988 |
Current status of D-penicillamine therapy in Japan.
Topics: Activities of Daily Living; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Female; Humans; | 1988 |
[Antibodies to D-penicillamine in patients with chronic polyarthritis--diagnostic aid in undesired and insufficient drug effects?].
Topics: Adult; Aged; Antibodies; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Female; Humans; Ma | 1988 |
Breath pentane excretion as a marker of disease activity in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Breath Tests; Gold; Humans; Lipid Pe | 1988 |
Antibodies to histones in rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antibodies; Arthritis, Rheumatoid; Enzyme-Link | 1988 |
The clinical value of measuring immunoglobulins when assessing penicillamine therapy in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Follow-Up Studies; Humans; Immunoglobulins; Male; Middle | 1988 |
[Rheumatoid arthritis treated with penicillamine and bronchiolitis obliterans].
Topics: Aged; Arthritis, Rheumatoid; Bronchiolitis Obliterans; Female; Humans; Penicillamine; Respiratory Fu | 1988 |
Assay for D-penicillamine-protein conjugate in human plasma utilising chemical reduction followed by high-performance liquid chromatography with gold/mercury electrochemical detection.
Topics: Arthritis, Rheumatoid; Blood Proteins; Borohydrides; Chromatography, High Pressure Liquid; Disulfide | 1988 |
Penicillamine-induced pseudo-pseudoxanthoma elasticum in a patient with rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Female; Humans; Middle Aged; Penicillamine; Pseudoxanthoma Elasticum | 1988 |
Effects of piroxicam and D-penicillamine on T lymphocyte subpopulations, natural killer cells and rheumatoid factor production in rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Antibody Formation; Arthritis, Rheumatoid; Humans; Immunity, Cellular; Kill | 1988 |
D-penicillamine pharmacokinetics and action.
Topics: Animals; Arthritis, Rheumatoid; Biotransformation; Disulfides; Humans; In Vitro Techniques; Penicill | 1988 |
[Among the antinuclear antibodies in rheumatoid polyarthritis: antihistone antibodies detected by an immunoenzymatic technic].
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Antinuclear; Arthritis, Rheumatoid; Enzyme-Linked Immuno | 1988 |
Clinical implications of the presence of anti-Ro (SSA) antibodies in patients with rheumatoid arthritis.
Topics: Adult; Aged; Antibodies, Antinuclear; Arthritis, Rheumatoid; Greece; Humans; Lupus Erythematosus, Sy | 1988 |
Impaired glucose handling in active rheumatoid arthritis: effects of corticosteroids and antirheumatic treatment.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Azathiopri | 1987 |
[Penicillamine-induced pemphigus].
Topics: Arthritis, Rheumatoid; Biopsy; Female; Fluorescent Antibody Technique; Humans; Middle Aged; Pemphigu | 1987 |
Prolonged remission of severe refractory rheumatoid arthritis following allogeneic bone marrow transplantation for drug-induced aplastic anaemia.
Topics: Adult; Anemia, Aplastic; Arthritis, Rheumatoid; Bone Marrow Transplantation; Female; Gold; Humans; P | 1986 |
[Long-term course of chronic polyarthritis under basic drug therapy].
Topics: Adult; Age Factors; Arthritis, Rheumatoid; Azathioprine; Chloroquine; Female; Follow-Up Studies; Gol | 1988 |
Serum amino terminal type III procollagen peptide and serum hyaluronan in rheumatoid arthritis: relation to clinical and serological parameters of inflammation during 8 and 24 months' treatment with levamisole, penicillamine, or azathioprine.
Topics: Adult; Aged; Arthritis, Rheumatoid; Azathioprine; Female; Humans; Hyaluronic Acid; Levamisole; Male; | 1988 |
Postmarketing surveillance in rheumatology: analysis of purpura and upper abdominal pain.
Topics: Abdomen; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Drug Information Services; Gold; Humans; P | 1988 |
Therapeutic intervention in rheumatoid arthritis: a case-controlled comparison of seronegative and seropositive disease.
Topics: Arthritis, Rheumatoid; Female; Gold; Humans; Hydroxychloroquine; Male; Middle Aged; Penicillamine; R | 1988 |
[Treatment of chronic polyarthritis with low-dose methotrexate].
Topics: Adrenal Cortex Hormones; Adult; Aged; Antineoplastic Agents; Arthritis, Rheumatoid; Chloroquine; Dru | 1988 |
Identification of factors limiting the accurate measurement of plasma D-penicillamine in rheumatoid arthritis patients.
Topics: Arthritis, Rheumatoid; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Humans; O | 1988 |
[Bronchiolitis obliterans].
Topics: Arthritis, Rheumatoid; Bronchiolitis Obliterans; Humans; Penicillamine | 1988 |
[Acadione, a new long-term treatment of rheumatoid polyarthritis].
Topics: Amino Acids, Sulfur; Arthritis, Rheumatoid; Chemical Phenomena; Chemistry; Dose-Response Relationshi | 1988 |
[Immunotropic therapy of rheumatoid arthritis (prerequisites, results and principles)].
Topics: Adrenal Cortex Hormones; Antilymphocyte Serum; Arthritis, Rheumatoid; Autoimmune Diseases; Humans; I | 1988 |
Minimal change nephropathy and pemphigus vulgaris associated with penicillamine treatment of rheumatoid arthritis.
Topics: Acute Kidney Injury; Arthritis, Rheumatoid; Autoimmune Diseases; Humans; Kidney Tubular Necrosis, Ac | 1988 |
Penicillamine nephropathy.
Topics: Arthritis, Rheumatoid; HLA Antigens; Humans; Kidney Diseases; Penicillamine | 1988 |
Longterm followup of treatment with D-penicillamine for rheumatoid arthritis: effectivity and toxicity in relation to HLA antigens.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Female; Follow-Up Studies; HLA Antigens; HLA- | 1987 |
[3 cases of myasthenic syndrome induced by D-penicillamine].
Topics: Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Myasthenia Gravis; Penicillamine | 1987 |
Genetic markers in rheumatoid arthritis relationship to toxicity from D-penicillamine.
Topics: Arthritis, Rheumatoid; Disease Susceptibility; Genetic Markers; Histocompatibility Antigens Class II | 1986 |
HLA and disease manifestations in rheumatoid arthritis--a Canadian experience.
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Gold; Histocompatibility Antigens Class II; HLA Antigens | 1986 |
D-penicillamine effects on prostanoid production in adherent rheumatic synovial cells in primary culture.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Arthritis, Rheumatoid; Cells, Cultured; Dinoprost; Dinoprostone | 1987 |
[HLA system and complications of the treatment of rheumatoid polyarthritis with D-penicillamine].
Topics: Arthritis, Rheumatoid; Histocompatibility Antigens Class II; HLA Antigens; HLA-B8 Antigen; HLA-DR3 A | 1986 |
Penicillamine-induced proteinuria: risk factors.
Topics: Adult; Aged; Arthritis, Rheumatoid; Disease Susceptibility; Female; Histocompatibility Antigens Clas | 1986 |
D-penicillamine-induced polymyositis occurring in patients with rheumatoid arthritis: a report of two cases and demonstration of a positive lymphocyte stimulation test to D-penicillamine.
Topics: Arthritis, Rheumatoid; Female; HLA-DR Antigens; HLA-DR4 Antigen; Humans; Lymphocyte Activation; Midd | 1986 |
HLA-DR antigens in rheumatoid arthritis. A Swiss collaborative study; final report. Swiss Federal Commission for the Rheumatic Diseases, Subcommission for Research.
Topics: Aged; Arthritis, Rheumatoid; Female; Gold; HLA-D Antigens; HLA-DR Antigens; HLA-DR1 Antigen; HLA-DR4 | 1986 |
HLA-D antigens in rheumatoid arthritis and toxicity to gold and penicillamine.
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Gold; HLA-D Antigens; HLA-DR Antigens; HLA-DR4 Antigen; | 1986 |
[Polymyositis induced by D-penicillamine treatment of rheumatoid arthritis: apropos of 2 cases with antinuclear antibodies].
Topics: Adult; Antibodies, Antinuclear; Arthritis, Rheumatoid; Female; Humans; Myositis; Penicillamine | 1986 |
Association of HLA DR1 with high D-penicillamine binding to monocytes in females.
Topics: Arthritis, Rheumatoid; Female; Flow Cytometry; HLA-D Antigens; HLA-DR Antigens; HLA-DR1 Antigen; Hum | 1987 |
Phenotype of peripheral blood lymphocytes in patients with progressive systemic sclerosis: activated T lymphocytes and the effect of D-penicillamine therapy.
Topics: Adult; Antibodies, Monoclonal; Antigens, Surface; Arthritis, Rheumatoid; Female; Humans; Lymphocyte | 1987 |
Penicillamine induced polymyositis and dermatomyositis.
Topics: Adult; Aged; Antibodies, Antinuclear; Arthritis, Rheumatoid; Autoantibodies; Dermatomyositis; Female | 1987 |
Cicatricial pemphigoid in a patient with rheumatoid arthritis treated with D-penicillamine.
Topics: Arthritis, Rheumatoid; Female; Humans; Middle Aged; Pemphigoid, Benign Mucous Membrane; Penicillamin | 1986 |
[Long-term results of D-penicillamine treatment in rheumatoid arthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Drug Evaluation; Female; Follow-Up Studies; Humans; Male; Middle | 1986 |
Nephrotic syndrome in a woman with diabetes mellitus and rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Diabetic Nephropathies; Diagnosis, Differential; Female; Humans; Kidney; Lupu | 1987 |
[Induced pemphigus].
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Follow-Up Studies; Humans; Male; Middle Aged; Pemphigus; | 1987 |
Failure to show a fall in peripheral blood lymphocytes in patients receiving gold or penicillamine for rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Gold; Humans; Leukocyte Count; Lymphocytes; Male; Middle | 1987 |
Goodpasture's syndrome in a patient receiving penicillamine and carbimazole.
Topics: Anti-Glomerular Basement Membrane Disease; Arthritis, Rheumatoid; Autoantibodies; Biopsy; Carbimazol | 1987 |
[Myasthenia as a complication of D-penicillamine therapy of rheumatoid arthritis].
Topics: Arthritis, Rheumatoid; Humans; Male; Middle Aged; Myasthenia Gravis; Penicillamine | 1987 |
Lipid peroxidation and malondialdehyde in the synovial fluid and plasma of patients with rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Azathioprine; Glucuronidase; Gold; H | 1987 |
The induction of an erosive arthropathy in the guinea pig with copper II bisglycinate and its treatment with antirheumatic drugs.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Disease Models, Animal; Glycine | 1987 |
Serum concentration of vitamin D metabolites in rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Female; Glucocorticoids; Gold; Humans; Male; Middle Aged; Penicillamin | 1987 |
[Penicillamine].
Topics: Animals; Arthritis, Rheumatoid; Humans; Penicillamine | 1987 |
Concomitant rheumatoid arthritis and Marfan's syndrome.
Topics: Adult; Arthritis, Rheumatoid; Drug Therapy, Combination; Humans; Male; Marfan Syndrome; Penicillamin | 1987 |
Serum lipoprotein in active rheumatoid arthritis and other chronic inflammatory arthritides. II. Effects of anti-inflammatory and disease-modifying drug treatment.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis | 1987 |
[Liver complications caused by D-penicillamine. Apropos of a case].
Topics: Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Humans; Middle A | 1986 |
[3 cases of obliterating bronchiolitis during treatment of rheumatoid polyarthritis with D-penicillamine].
Topics: Adult; Arthritis, Rheumatoid; Bronchitis; Female; Humans; Middle Aged; Penicillamine; Pulmonary Fibr | 1986 |
[Sulfhydryl maintenance treatment in rheumatoid polyarthritis. A series of 120 cases followed for 10 years and a study of possibilities of changing the drug].
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Follow-Up Studies; Gold; Humans; Male; Middle Aged; Peni | 1986 |
[Tiopronine and rheumatoid polyarthritis].
Topics: Adrenal Cortex Hormones; Amino Acids, Sulfur; Arthritis, Rheumatoid; Female; Humans; Male; Middle Ag | 1986 |
[D-penicillamine in the treatment of rheumatoid polyarthritis. 104 cases with a 5-year follow-up].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Arthritis, Juvenile; Arthritis, Rheumatoid; Blood | 1986 |
D-penicillamine-induced polymyositis in patients with rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Female; Humans; Middle Aged; M | 1986 |
Toxic epidermal necrolysis with extensive mucosal erosions of the gastrointestinal and respiratory tracts.
Topics: Acetaminophen; Arthritis, Rheumatoid; Biopsy; Chlormezanone; Drug Combinations; Female; Humans; Inte | 1986 |
Penicillamine-induced exacerbation of rheumatoid arthritis.
Topics: Acute Disease; Aged; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Humans; Knee Joint; Ma | 1986 |
Serum amino-terminal type III procollagen peptide in rheumatoid arthritis. Relationship to disease activity, treatment, and development of joint erosions.
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Humans; Joints; Male; Middle Aged; Penicillamine; Peptid | 1986 |
Impact of specific therapy upon rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Drug Evaluation; Drug Therapy; Female; Gold; Humans | 1986 |
The use of D-penicillamine in patients with rheumatoid arthritis undergoing hemodialysis.
Topics: Arthritis, Rheumatoid; Cysteine; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Penicil | 1986 |
Bone loss in rheumatoid arthritis and primary generalized osteoarthrosis: effects of corticosteroids, suppressive antirheumatic drugs and calcium supplements.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Bone Resorption; Calcium; | 1986 |
[Surveys of the epidemiological team of the French Rheumatology Society (RESFR) on the prescription of D-penicillamine in the treatment of rheumatoid polyarthritis].
Topics: Adult; Arthritis, Rheumatoid; Drug Utilization; Female; France; Humans; Male; Middle Aged; Penicilla | 1986 |
[Myasthenia induced by D-penicillamine during the treatment of rheumatoid polyarthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Myasthenia Gravis; Penicillam | 1986 |
Changes in glutathione in intact erythrocytes during incubation with penicillamine as detected by 1H spin-echo NMR spectroscopy.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Erythrocytes; Glutathione; Humans; Lactates; Magnet | 1986 |
Determination of D-penicillamine with an amino acid analyser using fluorescence detection.
Topics: Amino Acids; Arthritis, Rheumatoid; Autoanalysis; Humans; Penicillamine; Spectrometry, Fluorescence | 1986 |
[Long-term use of D-penicillamine in systemic scleroderma and rheumatoid arthritis].
Topics: Adolescent; Adult; Aged; Arthritis, Juvenile; Arthritis, Rheumatoid; Female; Humans; Male; Middle Ag | 1986 |
Myasthenia gravis caused by penicillamine and chloroquine therapy for rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Chloroquine; Dose-Response Relationship, Drug; Humans; Male; Myastheni | 1986 |
D-penicillamine induced myasthenia gravis. Its relevance for the anaesthetist.
Topics: Apnea; Arthritis, Rheumatoid; Female; Humans; Middle Aged; Myasthenia Gravis; Penicillamine; Postope | 1986 |
The influence of D-penicillamine on trace element excretion.
Topics: Arthritis, Rheumatoid; Cobalt; Female; Humans; Penicillamine; Selenium; Trace Elements; Zinc | 1986 |
Selenium treatment in rheumatoid arthritis.
Topics: Antimalarials; Arthritis, Rheumatoid; Double-Blind Method; Gold; Humans; Penicillamine; Selenium | 1986 |
Drugs for rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites; Arthritis, Rheum | 1987 |
[Physiopathology of rheumatoid polyarthritis for today's and tomorrow's therapists].
Topics: Adrenal Cortex Hormones; Antimalarials; Arthritis, Rheumatoid; Gold; Humans; Penicillamine; Sulfhydr | 1986 |
Disease-modifying drug therapy in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Antineoplastic Age | 1986 |
Recurrent acute renal failure with interstitial nephritis due to D-penicillamine.
Topics: Acute Kidney Injury; Arthritis, Rheumatoid; Humans; Male; Middle Aged; Nephritis, Interstitial; Peni | 1987 |
Acquired sideroblastic anaemia after aplastic anaemia caused by D-penicillamine therapy for rheumatoid arthritis.
Topics: Aged; Anemia, Aplastic; Anemia, Sideroblastic; Arthritis, Rheumatoid; Humans; Male; Penicillamine | 1987 |
Membranous glomerulonephritis in rheumatoid arthritis not related to gold or D-penicillamine therapy: a report of four cases and review of the literature.
Topics: Adult; Arthritis, Rheumatoid; Biopsy; Female; Glomerulonephritis; Gold; HLA Antigens; Humans; Kidney | 1987 |
Hypocholesterolaemia and abnormal high-density lipoprotein in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Apolipoproteins B; Arthritis, Rheumatoid; Cholesterol; Cholesterol, LDL; C | 1985 |
Anti-Ro(SSA) positive rheumatoid arthritis (RA): a clinicoserological group of patients with high incidence of D-penicillamine side effects.
Topics: Adult; Antibodies, Antinuclear; Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Penicillam | 1985 |
Lung biopsy in rheumatoid arthritis.
Topics: Antibodies, Antinuclear; Arthritis, Rheumatoid; Biopsy; Female; Gold; Humans; Lung; Lung Diseases; M | 1985 |
Rheumatoid factors and HLA-DR4 in RA.
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Gold; Histocompatibility Antigens Class II; HLA-DR4 Anti | 1985 |
HLA antigens and toxic reactions to sodium aurothiopropanol sulphonate and D-penicillamine in patients with rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Dimercaprol; Female; Gold; Histocompat | 1985 |
D-penicillamine induced suppression of B cell function: in vivo effect of D-penicillamine.
Topics: Adult; Aged; Arthritis, Rheumatoid; B-Lymphocytes; Female; Humans; Immunoglobulins; Male; Middle Age | 1985 |
Neoplasms of the immune system in rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Adult; Age Factors; Aged; Antineoplastic Agents; Arthritis, Rheumatoid; Fem | 1985 |
Effect of drug therapy on circulating and synovial fluid Ig-secreting cells in rheumatoid arthritis.
Topics: Adult; Anti-Inflammatory Agents; Antibody-Producing Cells; Arthritis, Rheumatoid; Female; Gold; Hemo | 1985 |
Cicatricial pemphigoid in D-penicillamine treated patients with rheumatoid arthritis--a report of three cases.
Topics: Aged; Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Pemphigoid, Benign Mucous Membrane; | 1985 |
Practical results of treatment with disease-modifying antirheumatoid drugs.
Topics: Arthritis, Rheumatoid; Azathioprine; Chloroquine; Drug Evaluation; Gold Sodium Thiomalate; Humans; P | 1985 |
Second line therapy in rheumatoid arthritis--a four year prospective study.
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Blood Sedimentation; Follow-Up Studies | 1985 |
Effect of antirheumatic agents on the mitogen response of arthritic rat spleen cells.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Arthritis, Rheumatoid; Chloro | 1985 |
HLA associations in aurothioglucose- and D-penicillamine-induced haematotoxic reactions in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Aurothioglucose; Female; Gene Frequency; Gold; Histocompatibilit | 1985 |
Ankylosing spondylitis and rheumatoid arthritis in a patient with Paget's disease. Differential effects of indomethacin, D-penicillamine, or gold sodium thiomalate in the respective arthritides.
Topics: Aged; Arthritis, Rheumatoid; Gold Sodium Thiomalate; Histocompatibility Antigens Class II; HLA Antig | 1985 |
Slow acting anti-rheumatic drugs in the treatment of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Aurothioglucose; Azathioprine; Cyclophosphamide; Gold; Gold Sodium Thiomalate | 1985 |
Rheumatoid arthritis: treatment which controls the C-reactive protein and erythrocyte sedimentation rate reduces radiological progression.
Topics: Arthritis, Rheumatoid; Blood Sedimentation; C-Reactive Protein; Chloroquine; Dapsone; Drug Evaluatio | 1986 |
Increased binding of D-penicillamine to monocytes in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Carrier Proteins; Female; Flow Cytometry; Humans; Male; Middle A | 1986 |
Progressive proliferative glomerulonephritis in a patient with rheumatoid arthritis treated with D-penicillamine.
Topics: Arthritis, Rheumatoid; Creatinine; Glomerulonephritis; Humans; Male; Middle Aged; Penicillamine | 1986 |
Anti-Ro positive rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Humans; Penicillamine | 1986 |
Differential effects of therapeutic regimens on specific classes of rheumatoid factor.
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Drug Therapy, Combination; Female; Gol | 1986 |
Influence of previous gold treatment and other patient variables on outcome of treatment with disease modifying anti-rheumatic drugs (DMARD) in patients with rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Azathioprine; Female; Gold; HLA Antigens; Humans; Levamisole; Male; Middle Ag | 1986 |
Measurement of penicillamine and N-acetylcysteine in human blood by high-performance liquid chromatography and electrochemical detection.
Topics: Acetylcysteine; Arthritis, Rheumatoid; Chromatography, High Pressure Liquid; Drug Stability; Electro | 1986 |
IgM nephropathy associated with penicillamine.
Topics: Arthritis, Rheumatoid; Humans; Immunoglobulin M; Kidney Glomerulus; Male; Middle Aged; Nephrotic Syn | 1986 |
Treating joint inflammation in the elderly: an update.
Topics: Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antimalarials; Arthritis; Arthritis, Infectio | 1985 |
Beneficial effect of intravenous cyclophosphamide and oral prednisone on D-penicillamine-associated bronchiolitis obliterans.
Topics: Administration, Oral; Adult; Arthritis, Rheumatoid; Bronchitis; Constriction, Pathologic; Cyclophosp | 1985 |
Free thiomalate levels in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Humans; Penicillamine | 1985 |
The effect of glucocorticoids on bone mass in rheumatoid arthritis patients. Influence of menopausal state.
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Bone and Bones; Drug Therapy, Combinat | 1985 |
Insulin antibodies in patients receiving penicillamine.
Topics: Adult; Arthritis, Rheumatoid; Autoantibodies; Female; Humans; Hypoglycemia; Insulin Antibodies; Male | 1985 |
The development of screening tests for D-penicillamine-like antirheumatic activity based on in vivo interactions with copper.
Topics: Animals; Arthritis, Rheumatoid; Capillary Permeability; Copper; Drug Interactions; Extremities; Fema | 1985 |
A case of cholestatic hepatitis associated with D-penicillamine therapy for rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Huma | 1985 |
[Adverse effects of D-penicillamine in rheumatoid arthritis with reference to prior gold therapy].
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Female; Gold; Humans; Male; Middle Aged; Penicillami | 1985 |
Rapidly progressive glomerulonephritis in a patient with rheumatoid arthritis during treatment with high-dosage D-penicillamine.
Topics: Arthritis, Rheumatoid; Female; Glomerulonephritis; Hematuria; Humans; Kidney Glomerulus; Middle Aged | 1985 |
[Superficial pemphigus during the treatment of rheumatoid polyarthritis with D-penicillamine and piroxicam (Feldene)].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Azathioprine; Drug Therapy, Combination; H | 1985 |
Neuromuscular disorders associated with D-penicillamine treatment for rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Myasthenia Gravis; Myositis; Neurom | 1985 |
Remission of arthritis and radiological improvement after combination therapy for non-Hodgkin's lymphoma in a patient with rheumatoid arthritis undergoing treatment with D-penicillamine.
Topics: Antineoplastic Combined Chemotherapy Protocols; Arthritis, Rheumatoid; Humans; Lymphoma; Male; Middl | 1985 |
Remission in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Female; Gold; Humans; Male; Middle Aged; Penicillamine; Remission, Spontaneou | 1985 |
The clinical features of elderly-onset rheumatoid arthritis. A comparison with younger-onset disease of similar duration.
Topics: Adrenal Cortex Hormones; Adult; Age Factors; Aged; Antineoplastic Agents; Arthritis, Rheumatoid; Fem | 1985 |
[Influence of treatment on the chemotaxis of polymorphonuclear neutrophils in rheumatoid arthritis].
Topics: Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chemotaxis, L | 1985 |
Antimalarial treatment of rheumatoid arthritis: 1985 status.
Topics: Antimalarials; Arthritis, Rheumatoid; Chloroquine; Drug Combinations; Gold; Humans; Hydroxychloroqui | 1985 |
[Serum levels of zinc and copper in rheumatoid arthritis].
Topics: Arthritis, Rheumatoid; Copper; Female; Gold; Humans; Male; Penicillamine; Zinc | 1985 |
Azathioprine in 50 rheumatoid arthritic patients intolerant or unresponsive to gold or penicillamine.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Azathioprine; Blood Sedimentation; Female; Gold; Hem | 1985 |
C-reactive protein levels in patients with rheumatoid arthritis: the impact of therapy.
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Blood Sedimentation; C-Reactive Protei | 1985 |
[Drug therapy of rheumatoid arthritis].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Gold; Humans; Immunosuppre | 1985 |
Lupus-like syndrome induced by D-penicillamine in Wilson's disease.
Topics: Adult; Antigen-Antibody Reactions; Arthritis, Rheumatoid; Autoantibodies; Cystinuria; Female; Hapten | 1971 |
Rheumatoid neuropathy.
Topics: Arteritis; Arthritis, Rheumatoid; Blood Sedimentation; Foot Diseases; gamma-Globulins; Humans; Neura | 1971 |
D(-)penicillamine in morphoea (localised scleroderma).
Topics: Arthritis, Rheumatoid; Humans; Penicillamine; Scleroderma, Localized | 1973 |
Penicillamine in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Humans; Penicillamine | 1973 |
Effects of D(-) penicillamine on polymeric structural collagen of skin.
Topics: Arthritis, Rheumatoid; Collagen; Humans; Penicillamine; Prednisolone; Skin | 1973 |
Penicillamine in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Humans; Penicillamine | 1973 |
Penicillamine in rheumatoid arthritis.
Topics: Agranulocytosis; Anemia, Aplastic; Arthritis, Rheumatoid; Humans; Penicillamine | 1973 |
Letter: Peptic ulceration and D-penicillamine.
Topics: Arthritis, Rheumatoid; Hepatolenticular Degeneration; Humans; Penicillamine; Peptic Ulcer; Peptic Ul | 1974 |
[D-penicillamine induced lupus during the treatment of rheumatoid arthritis. Report of 2 cases and systematic immunologic study during the treatment].
Topics: Antibodies, Antinuclear; Arthritis, Rheumatoid; Female; Fluorescent Antibody Technique; Follow-Up St | 1974 |
Letter: Penicillamine and zinc.
Topics: Administration, Oral; Arthritis, Rheumatoid; Drug Therapy, Combination; Humans; Penicillamine; Taste | 1974 |
Letter: Penicillamine and zinc.
Topics: Arthritis, Rheumatoid; Humans; Penicillamine; Taste Disorders; Zinc | 1974 |
Letter: Anti-inflammatory drugs and tissue copper.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Copper; Humans; Liver Cirrhosis; Penicillamine; Pro | 1974 |
[Short report on the possibilities of an immunosuppressive treatment in pulmonary diseases].
Topics: Adolescent; Adrenal Cortex Hormones; Alkylating Agents; Antimetabolites; Arthritis, Rheumatoid; Aspa | 1974 |
[Rheumatic and pararheumatic diseases. Problems of diagnosis and therapy].
Topics: Antineoplastic Agents; Arthritis, Rheumatoid; Collagen Diseases; Dermatomyositis; Humans; Lupus Eryt | 1973 |
[DNA-synthesizing lymphocytes in the blood of patients with disseminated lupus erythematosus, rheumatoid arthritis, and panarteritis nodosa (author's transl)].
Topics: Adult; Aged; Arthritis, Rheumatoid; Azathioprine; Chloroquine; DNA; Female; Gold; Humans; Indomethac | 1973 |
Effect of penicillamine on human collagen and its possible application to treatment of scleroderma.
Topics: Adult; Aged; Arthritis, Rheumatoid; Collagen; Cystinuria; Female; Hepatolenticular Degeneration; Hum | 1966 |
Decreased taste sensitivity after D-penicillamine reversed by copper administration.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Ceruloplasmin; Child; Copper; Cystinuria; Female; He | 1967 |
Rheumatoid arthritis with secondary amyloidosis and malabsorption syndrome. Effect of D-penicillamine.
Topics: Adult; Amyloidosis; Arthritis, Rheumatoid; Digestive System; gamma-Globulins; Hemoglobinometry; Huma | 1968 |
Nephropathy induced by D-penicillamine.
Topics: Adult; Arthritis, Rheumatoid; Complement System Proteins; Female; Fluorescent Antibody Technique; ga | 1968 |
Cryoglobulinemia and disease.
Topics: Adult; Anemia, Hemolytic; Arthritis, Rheumatoid; Autoantibodies; Autoimmune Diseases; Beta-Globulins | 1970 |
D-penicillamine for the treatment of gold dermatitis.
Topics: Activation Analysis; Arthritis, Rheumatoid; Drug Eruptions; Feces; Female; Gold; Humans; Middle Aged | 1969 |
Tryptophan metabolism in man (with special reference to rheumatoid arthritis and scleroderma).
Topics: Arthritis, Rheumatoid; Aspirin; Cystinuria; Drug Synergism; Edetic Acid; Humans; Kynurenic Acid; Kyn | 1973 |
[Treatment of chronic polyarthritis].
Topics: Adrenocorticotropic Hormone; Arthritis, Rheumatoid; Chloroquine; Gold; Humans; Hydrotherapy; Immunos | 1967 |
[Rheumatoid polyarthritis with diffuse arteritis. Dissociated action of penicillamine].
Topics: Adult; Arteritis; Arthritis, Rheumatoid; Autopsy; Female; Humans; Methylprednisolone; Penicillamine; | 1971 |
Recent drugs and the rheumatic diseases.
Topics: Acetaminophen; Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non- | 1974 |
[Favorable course of a case of periarteritis nodosa occurring during rheumatoid arthritis and treated with penicillamine and chlorambucil. Presentation of patient].
Topics: Adult; Arthritis, Rheumatoid; Chlorambucil; Humans; Male; Penicillamine; Polyarteritis Nodosa | 1965 |
Letter: Penicillamine and creaking joints.
Topics: Arthritis, Rheumatoid; Humans; Joint Diseases; Penicillamine; Rheology; Synovial Fluid | 1974 |
[To be noted in D-penicillamine therapy].
Topics: Arthritis, Rheumatoid; Blood Platelets; Chronic Disease; Hepatitis; Humans; Leukocytes; Penicillamin | 1974 |
[D-Penicillamine in adjuvant arthritis of rats].
Topics: Adjuvants, Immunologic; Animals; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Edema; Fem | 1974 |
[Clinical experiences in the use of the synthetic D-Penicillamine Trolovol in the treatment of chronic polyarthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Chemical Analysis; Drug Evaluation; Female; Humans; Male; | 1974 |
Observations on lactic dehydrogenase activity in blood of patients treated with D-penicillamine for rheumatoid arthritis.
Topics: Acid Phosphatase; Alkaline Phosphatase; Arthritis, Rheumatoid; Aspartate Aminotransferases; Creatine | 1974 |
The actionof D-penicillamine on collagen in scleroderma and osteoarthrosis.
Topics: Arthritis, Rheumatoid; Collagen; Humans; In Vitro Techniques; Osteoarthritis; Penicillamine; Sclerod | 1974 |
Effects of D(-)penicillamine on skin collagen in man.
Topics: Adult; Aged; Arthritis, Rheumatoid; Collagen; Female; Humans; Male; Middle Aged; Penicillamine; Skin | 1974 |
Observations on in vivo skin elasticity and skin thickness of patients with rheumatoid arthritis treated with D-penicillamine and gold salts.
Topics: Adult; Arthritis, Rheumatoid; Elasticity; Female; Gold; Humans; Male; Middle Aged; Penicillamine; Sk | 1974 |
Some immunological changes in rheumatoid arthritis among patients receiving penicillamine and gold.
Topics: Arthritis, Rheumatoid; Complement C3; Gold; Humans; Immunoglobulins; Immunosuppressive Agents; Penic | 1974 |
Experience with penicillamine and azathioprine in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Azathioprine; Drug Therapy, Combination; Humans; Penicillamine; Proteinuria | 1974 |
Hazards of penicillamine therapy in the treatment of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Humans; Penicillamine | 1974 |
[Our 1st experiences with the use of D-penicillamine in the treatment of rheumatoid arthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Drug Evaluation; Humans; Middle Aged; Penicillamine | 1974 |
Penicillamine in the hands of the family doctor.
Topics: Albuminuria; Arthritis, Rheumatoid; Blood Platelet Disorders; Follow-Up Studies; Humans; Leukopenia; | 1974 |
[Stomatitis caused by D-penicillamine].
Topics: Arthritis, Rheumatoid; Drug Hypersensitivity; Epidermolysis Bullosa; Female; Hepatolenticular Degene | 1973 |
Selection of patients with rheumatoid arthritis to be treated with penicillamine, and their management.
Topics: Administration, Oral; Arthritis, Rheumatoid; Blood Platelet Disorders; Feeding and Eating Disorders; | 1974 |
[Penicillamine-induced polymyositis (author's transl)].
Topics: Aged; Antibodies; Antibodies, Antinuclear; Arthritis, Rheumatoid; Autoimmune Diseases; Collagen; Cor | 1974 |
[Panmyelophthisis induced by the treatment of primary-chronic polyarthritis with gold and D-penicillamine].
Topics: Anemia, Myelophthisic; Arthritis, Rheumatoid; Aurothioglucose; Bone Marrow; Bone Marrow Examination; | 1973 |
[Optimal therapy for rheumatoid arthritis in the Peoples' Republic of Poland].
Topics: Arthritis, Rheumatoid; Aspirin; Cyclophosphamide; Gold; Health Resorts; Humans; Indomethacin; Penici | 1972 |
[Therapy of chronic polyarthritis. 1. Causal therapy, basic drug therapy].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chloroquine; Gold; Humans; Immunosuppressive Agents | 1972 |
Combined treatment of scleromalacia perforans in rheumatoid arthritis with penicillamine and plastic surgery.
Topics: Arthritis, Rheumatoid; Eye Manifestations; Fascia Lata; Female; Fluprednisolone; Humans; Middle Aged | 1973 |
Properties of skin polymeric collagen in patients with rheumatoid arthritis and normal controls.
Topics: Arthritis, Rheumatoid; Collagen; Humans; Penicillamine; Skin | 1973 |
Penicillamine in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Humans; Leukocyte Count; Penicillamine | 1973 |
Reaction to D-penicillamine in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Humans; Male; Middle Aged; Muscle Rigidity; Pain; Penicillamine; Taste Disord | 1973 |
Penicillamine in the treatment of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Humans; Penicillamine | 1973 |
[Cuprenil in the treatment of rheumatoid arthritis].
Topics: Arthritis, Rheumatoid; Evaluation Studies as Topic; Female; Humans; Male; Penicillamine; Time Factor | 1973 |
Reaction to D-penicillamine in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Humans; Penicillamine; Taste Disorders | 1973 |
[D-penicillamine].
Topics: Arthritis, Rheumatoid; Cystinuria; Hepatolenticular Degeneration; Humans; Penicillamine | 1973 |
Reaction to D-penicillamine in rheumatoid arthritis.
Topics: Analgesics; Arthritis, Rheumatoid; Humans; Penicillamine; Substance Withdrawal Syndrome | 1973 |
[Operative treatment of rheumatoid arthritis and its radiography].
Topics: Arthritis, Rheumatoid; Arthrodesis; Arthroplasty; Chloroquine; Fingers; Gold; Humans; Indomethacin; | 1973 |
Effect of D-penicillamine on serum immunoglobulins and rheumatoid factor.
Topics: Animals; Arthritis, Rheumatoid; Hemagglutination; Humans; Immunoglobulin A; Immunoglobulin G; Immuno | 1973 |
[Nephrotic syndrome due to penicillamine (author's transl)].
Topics: Adult; Arthritis, Rheumatoid; Biopsy; Exanthema; Female; Humans; Immunoglobulin G; Kidney; Nephrotic | 1973 |
Letter: Penicillamine in the treatment of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Humans; Penicillamine | 1973 |
[Therapeutic effect of d-penicillamine in scleroderma].
Topics: Adolescent; Adult; Arthritis, Rheumatoid; Evaluation Studies as Topic; Female; Humans; Male; Middle | 1973 |
[Comparison of therapeutic effects of various immunosuppressive drugs in rheumatoid arthritis].
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Azathioprine; Drug Therapy, Combination; Female; Hum | 1973 |
Sudden gigantism of breasts: drug induced?
Topics: Adult; Arthritis, Rheumatoid; Body Weight; Breast Diseases; Female; Humans; Hypertrophy; Mastectomy; | 1973 |
[The basal therapy of rheumatoid arthritis with d-penicillamine (author's transl)].
Topics: Arthritis, Rheumatoid; Humans; Penicillamine; Proteinuria; Thrombocytopenia; Time Factors | 1973 |
Drug-induced nephropathies.
Topics: Animals; Arthritis, Rheumatoid; Aspirin; Colic; Complement System Proteins; Glomerular Filtration Ra | 1973 |
[Immune complex nephritis with nephrotic syndrome following D-penicillamine therapy].
Topics: Adult; Antigen-Antibody Complex; Arthritis, Rheumatoid; Biopsy; Female; Glomerulonephritis; Humans; | 1974 |
[Basic treatment of rheumatoid arthritis].
Topics: Adult; Antimalarials; Arthritis, Rheumatoid; Female; Gold; Humans; Immunosuppressive Agents; Male; M | 1974 |
[Nephrotic syndrome and inflammation of the thyroid gland after D-penicillamine].
Topics: Anabolic Agents; Arthritis, Rheumatoid; Cortisone; Female; Humans; Middle Aged; Nephrotic Syndrome; | 1974 |
[Effect of D-penicillamine on blood clotting (author's transl)].
Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Coagulation; Blood Coagulation Disorders; Blood Coagulatio | 1974 |
[Studies on the mechanism of action of D-penicillamine].
Topics: Arthritis, Rheumatoid; DNA; DNA Repair; Humans; Penicillamine; Tritium | 1974 |
[Clinical picture of rheumatologic diseases. Current status of cytostatic therapy].
Topics: Antineoplastic Agents; Arthritis, Rheumatoid; Azathioprine; Chlorambucil; Cyclophosphamide; Humans; | 1974 |
[Round-table discussion on the surgical treatment of arthropathies].
Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Arthrodesis; Arthroplasty; Biopsy; Female; Finger Jo | 1974 |
Penicillamine for rheumatoid arthritis.
Topics: Administration, Oral; Arthritis, Rheumatoid; Female; Humans; Middle Aged; Penicillamine | 1974 |
[Gold therapy in chronic joint rheumatism].
Topics: Acute Kidney Injury; Arthritis, Rheumatoid; Dimercaprol; Drug Hypersensitivity; Gold; Hematologic Di | 1967 |
[Comparative studies on the effects of penicillamine-base and penicillamine-HCl in vitro].
Topics: Alkalies; Arthritis, Rheumatoid; Blood Protein Electrophoresis; Humans; Hydrochloric Acid; Hydrogen- | 1968 |
[Effect of D-penicillamine and cysteamine on the activity of the rheumatoid factor in vivo and in vitro].
Topics: Adult; Arthritis, Rheumatoid; Cysteamine; Female; Humans; In Vitro Techniques; Latex Fixation Tests; | 1969 |
[The copper chelating effect of D-penicillamine in the long-term therapy of progressive chronic polyarthritis].
Topics: Adult; Anthropometry; Arthritis, Rheumatoid; Blood Proteins; Chronic Disease; Copper; Erythrocyte Co | 1970 |
[The long term treatment of rheumatoid arthritis with D-penicillamine].
Topics: Administration, Oral; Adult; Arthritis, Rheumatoid; Blood Cell Count; Blood Sedimentation; Collagen; | 1969 |
[Results of Cuprenil (D-penicillamine) treatment in patients with rheumatoid arthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Evaluation Studies as Topic; Female; Humans; Male; Middle Aged; | 1972 |
[Cytostatic therapy of rheumatoid arthritis].
Topics: Antineoplastic Agents; Arthritis, Rheumatoid; Humans; Immunosuppressive Agents; Penicillamine | 1972 |
Rheumatoid arthritis and malabsorption.
Topics: Arthritis, Rheumatoid; Humans; Intestinal Absorption; Penicillamine; Pyridoxine | 1972 |
[Penicillamine in the therapy of progressive polyarthritis. (2 initial therapeutic attempts with small doses of penicillamine hydrochloride and base)].
Topics: Adult; Aged; Arthritis, Rheumatoid; Chronic Disease; Drug Tolerance; Humans; Middle Aged; Penicillam | 1972 |
Penicillamine in the treatment of rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; Blood Sedimentation; Gangrene; Humans; Middle Aged; Nausea; Penicillami | 1972 |
[Study of various parameters of cellular and humoral immunity during the treatment of rheumatoid polyarthritis with D-penicillamine].
Topics: Agglutinins; Antibodies; Antibody Formation; Arthritis, Rheumatoid; Hemagglutination Tests; Humans; | 1972 |
Biologically oriented organic sulfur chemistry. 8. Structure-activity relationships of penicillamine analogs and derivatives.
Topics: Acetamides; Alcohols; Amides; Amines; Amino Acids; Animals; Arthritis, Rheumatoid; Carboxylic Acids; | 1971 |
[A case of pemphigus induced by D-penicillamine. Does iatrogenic pemphigus exist?].
Topics: Arthritis, Rheumatoid; Autoantibodies; Biopsy; Cytodiagnosis; Drug Synergism; Female; Fluorescent An | 1971 |
[Treatment of common rheumatoid polyarthritis with D-penicillamine].
Topics: Arthritis, Rheumatoid; Blood Sedimentation; Humans; Immunoglobulins; Lymphocyte Activation; Penicill | 1971 |
[Treatment of rheumatoid arthritis with D-penicillamine].
Topics: Adult; Arthritis, Rheumatoid; Copper; Female; Humans; Immunoglobulin G; Immunoglobulins; Immunosuppr | 1971 |
[Indications for indomethacin rheumatic disease with special reference to its combination with immunosuppressive agents].
Topics: Arthritis, Rheumatoid; Drug Synergism; Female; Humans; Hydrazines; Immunosuppressive Agents; Indomet | 1971 |
Antivitamin B6 effect of D-penicillamine.
Topics: Arthritis, Rheumatoid; Humans; Kynurenine; Penicillamine; Pyridoxine; Rheumatoid Factor; Stereoisome | 1969 |
Rheumatoid vasculitis. Report of a second case treated with penicillamine.
Topics: Arteritis; Arthritis, Rheumatoid; Endophthalmitis; Gangrene; Humans; Latex Fixation Tests; Male; Mid | 1968 |
[Effect of D-penicillamine on the latex fixation test, hemagglutination test and streptococci-L-agglutination in vitro].
Topics: Agglutination Tests; Antibodies, Anti-Idiotypic; Arthritis, Rheumatoid; Chronic Disease; Hemagglutin | 1971 |
[Dosage and adverse effects of commonly used antirheumatic agents].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chloroquine; Drug Combinations; Glucocorticoids; Go | 1971 |
Dermal connective tissue permeability in rheumatoid arthritics.
Topics: Adult; Animals; Arthritis, Rheumatoid; Ascorbic Acid; Carbamates; Cell Membrane Permeability; Connec | 1966 |
Degradation of synovial fluid and hyaluronic acid by serum and testicular hyaluronidase, and by L-ascorbic acid and the effect of inhibitors.
Topics: Adult; Alcohols; Animals; Arthritis, Rheumatoid; Ascorbic Acid; Cattle; Chemical Phenomena; Chemistr | 1969 |
[Immunosuppressive agents in the therapy of rheumatism].
Topics: Arthritis, Rheumatoid; Chlorambucil; Humans; Immunosuppressive Agents; Methotrexate; Penicillamine | 1969 |
Therapeutic studies of D-penicillamine in the treatment of rheumatoid arthritis.
Topics: Administration, Oral; Adult; Aged; Arthritis, Rheumatoid; Blood Proteins; Female; Hematocrit; Humans | 1969 |
[Therapy in seronegative chronic polyarthritis].
Topics: Adult; Arthritis, Rheumatoid; Diagnosis, Differential; Drug Antagonism; Female; Gold; Humans; Indome | 1970 |
[Experiences with D-penicillamine with chronic polyarthritis].
Topics: Arthritis, Rheumatoid; Gastritis; Humans; Hypersensitivity; Penicillamine; Rheumatoid Factor; Taste; | 1970 |
Observations on the treatment of rheumatoid disease with penicillamine.
Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Sedimentation; Female; Gastrointestinal Diseases; Humans; | 1970 |
[Penicillamine and rheumatoid polyarthritis (study of 9 cases)].
Topics: Adrenal Cortex Hormones; Adult; Age Factors; Aged; Arthritis, Rheumatoid; Drug Synergism; Drug Toler | 1970 |
[Basic therapy of progressive chronic polyarthritis].
Topics: Aged; Antineoplastic Agents; Arthritis, Rheumatoid; Chloroquine; Gold; Humans; Immunosuppressive Age | 1970 |
[Basic therapy in chronic polyarthritis].
Topics: Antineoplastic Agents; Arthritis, Rheumatoid; Azathioprine; Chronic Disease; Cyclophosphamide; Gold; | 1970 |
[Treatment of common rheumatoid polyarthritis with D-penicillamine. Study of a series of 22 cases].
Topics: Arthritis, Rheumatoid; Blood Sedimentation; Humans; Penicillamine; Prognosis; Rheumatoid Factor | 1971 |
[On the immunodepressive action of D-penicillamine in the treatment of progressive chronic polyarthritis].
Topics: Adolescent; Arthritis, Rheumatoid; Female; Humans; Immunosuppressive Agents; Male; Middle Aged; Peni | 1967 |
Effect of increased serum sulphydryl content on titre of rheumatoid factor.
Topics: Arthritis, Rheumatoid; Chelating Agents; Humans; Mercaptoethylamines; Penicillamine; Rheumatoid Fact | 1968 |
Nephrotic syndrome induced by penicillamine.
Topics: Arthritis, Rheumatoid; Female; Humans; Middle Aged; Nephrotic Syndrome; Penicillamine; Scleroderma, | 1968 |
Effects of penicillamine on the kidney and on taste.
Topics: Arthritis, Rheumatoid; Copper; Humans; Nephrotic Syndrome; Penicillamine; Taste | 1968 |
Penicillamine in rheumatoid disease with particular reference to rheumatoid factor.
Topics: Arthritis, Rheumatoid; Female; Humans; Middle Aged; Penicillamine; Rheumatoid Factor | 1968 |
Laboratory observations on the use of penicillamine in rheumatoid disease.
Topics: Arthritis, Rheumatoid; Blood Sedimentation; Female; Humans; Male; Penicillamine | 1968 |
[Comparative studies on the immunodepressive effect of D-penicillamine and gold salts in chronic progressive polyarhtritis].
Topics: Arthritis, Rheumatoid; Blood Sedimentation; Genetics, Medical; Globulins; Gold; Humans; Methods; Pen | 1968 |
[D-Penicillamine. A contribution on the therapy of chronic progressive polyarthritis].
Topics: Arthritis, Rheumatoid; Copper; Humans; Penicillamine; Rheumatoid Factor | 1968 |
[Recent methods of drug therapy in rheumatoid arthritis].
Topics: Arthritis, Rheumatoid; Glucocorticoids; Humans; Immunosuppressive Agents; Indomethacin; Penicillamin | 1968 |
Effects of SH-compounds on rheumatoid factors in rheumatoid arthritis.
Topics: Animals; Arthritis, Rheumatoid; Blood Protein Electrophoresis; Cysteine; Hemagglutination Tests; Hum | 1969 |
Biologically oriented organic sulfur chemistry. II. Formation of hemimercaptals or hemimercaptoles as a means of latentiating thiols.
Topics: Animals; Arthritis, Rheumatoid; Cobalt Isotopes; Mice; Penicillamine; Radiation Injuries, Experiment | 1969 |
Effects of lysosomal collagenolytic enzymes, anti-inflammatory drugs and other substances on some properties of insoluble collagen.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Cathepsins; Collagen; Copper; Cysteine; Hy | 1969 |
[Long-term treatment of chronic progredient polyarthritis with D-penicillamine].
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Female; Humans; Middle Aged; Penicillamine | 1969 |
The effect of penicillamine on the laboratory parameters in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Blood Sedimentation; C-Reactive Protein; Humans; Penicillamine; Rheumatoid Fa | 1965 |