penicillamine has been researched along with Arthritis, Degenerative in 23 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of our study was to determine the prevalence of thyroid dysfunction and autoimmune abnormalities in rheumatoid arthritis (RA) and to further investigate the possible association between D-penicillamine and autoimmune thyroiditis." | 5.08 | Thyroid function and immune profile in rheumatoid arthritis. A controlled study. ( Andonopoulos, AP; Christofidou, M; Makri, M; Markou, C; Siambi, V; Vagenakis, AG, 1996) |
| " Injectable gold compounds and penicillamine are not contraindicated in the elderly, because they are just as efficacious as in younger persons for the treatment of rheumatoid arthritis." | 4.76 | Problems of antiarthritic therapy in the elderly. ( Brooks, PM; Buchanan, WW; Kassam, Y; Kean, WF, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (65.22) | 18.7374 |
| 1990's | 4 (17.39) | 18.2507 |
| 2000's | 4 (17.39) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brooks, PM | 1 |
| Kean, WF | 1 |
| Kassam, Y | 1 |
| Buchanan, WW | 1 |
| Ehrlich, GE | 1 |
| Gerster, JC | 1 |
| Holden, G | 1 |
| Andonopoulos, AP | 1 |
| Siambi, V | 1 |
| Makri, M | 1 |
| Christofidou, M | 1 |
| Markou, C | 1 |
| Vagenakis, AG | 1 |
| Lindy, O | 1 |
| Konttinen, YT | 1 |
| Sorsa, T | 1 |
| Ding, Y | 1 |
| Santavirta, S | 1 |
| Ceponis, A | 1 |
| López-Otín, C | 1 |
| Honda, S | 2 |
| Migita, K | 2 |
| Hirai, Y | 2 |
| Ueki, Y | 2 |
| Yamasaki, S | 2 |
| Urayama, S | 2 |
| Kawabe, Y | 2 |
| Fukuda, T | 2 |
| Kawakami, A | 2 |
| Kamachi, M | 2 |
| Kita, M | 2 |
| Ida, H | 2 |
| Aoyagi, T | 2 |
| Eguchi, K | 2 |
| Borderie, D | 1 |
| Le Marechal, H | 1 |
| Ekindjian, OG | 1 |
| Hernvann, A | 1 |
| Studer, RK | 1 |
| Levicoff, E | 1 |
| Georgescu, H | 1 |
| Miller, L | 1 |
| Jaffurs, D | 1 |
| Evans, CH | 1 |
| Shibatomi, K | 1 |
| Lowe, JR | 1 |
| Pickup, ME | 1 |
| Dixon, JS | 1 |
| Leatham, PA | 2 |
| Rhind, VM | 1 |
| Wright, V | 2 |
| Downie, WW | 1 |
| Solomon, SD | 1 |
| Kolodny, AL | 1 |
| Klipper, AR | 1 |
| Reardon, EV | 1 |
| Clough, JD | 1 |
| Caldwell, CW | 1 |
| Bridges, AJ | 1 |
| Walker, SE | 1 |
| Smarr, KL | 1 |
| Reichert, RJ | 1 |
| Anderson, SK | 1 |
| Hewett, JE | 1 |
| Parker, JC | 1 |
| Sheikh, IA | 1 |
| Kaplan, AP | 1 |
| Wirth, W | 1 |
| Cashin, CH | 1 |
| Reid, DM | 1 |
| Kennedy, NS | 1 |
| Smith, MA | 1 |
| Nicoll, J | 1 |
| Brown, N | 1 |
| Tothill, P | 1 |
| Nuki, G | 1 |
| Hill, J | 1 |
| Bird, HA | 1 |
| Herbert, CM | 1 |
| Jayson, MI | 2 |
| Lindberg, KA | 1 |
| Bailey, AJ | 2 |
| Nimni, ME | 1 |
| Herbert, C | 1 |
4 reviews available for penicillamine and Arthritis, Degenerative
| Article | Year |
|---|---|
Problems of antiarthritic therapy in the elderly.
Topics: Adrenal Cortex Hormones; Age Factors; Aged; Allopurinol; Anti-Inflammatory Agents; Anti-Inflammatory | 1984 |
[Which anti-inflammatory agents should be used in rheumatology?].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Anticoagulants; Arthritis, Rheumatoid; Drug Syner | 1981 |
Update: treatment of rheumatic disease.
Topics: Allopurinol; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Gold; Gout; Humans; Lupus Erythematosu | 1978 |
Collagen: Its structure and function in normal and pathological connective tissues.
Topics: Age Factors; Amino Acids; Animals; Basement Membrane; Bone and Bones; Cartilage, Articular; Cattle; | 1974 |
1 trial available for penicillamine and Arthritis, Degenerative
| Article | Year |
|---|---|
Thyroid function and immune profile in rheumatoid arthritis. A controlled study.
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Monitoring, Immunologic; Oste | 1996 |
18 other studies available for penicillamine and Arthritis, Degenerative
| Article | Year |
|---|---|
Medical management and its impact on work.
Topics: Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Female; | 1982 |
Age and arthritis.
Topics: Adult; Age Factors; Aged; Arthritis; Arthritis, Rheumatoid; England; Female; Gold; Humans; Male; Mid | 1982 |
Matrix metalloproteinase 13 (collagenase 3) in human rheumatoid synovium.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Cartilage, Articular; Clodronic Acid; Collage | 1997 |
Induction of COX-2 expression by nitric oxide in rheumatoid synovial cells.
Topics: Arthritis, Rheumatoid; Base Sequence; Cells, Cultured; Cyclooxygenase 2; DNA Primers; Enzyme Inducti | 2000 |
Nitric oxide modifies glycolytic pathways in cultured human synoviocytes.
Topics: Cell Survival; Cells, Cultured; Deoxyglucose; Dose-Response Relationship, Drug; Glucose; Glyceraldeh | 2000 |
Nitric oxide inhibits chondrocyte response to IGF-I: inhibition of IGF-IRbeta tyrosine phosphorylation.
Topics: Animals; Cartilage, Articular; Cells, Cultured; Chondrocytes; Dose-Response Relationship, Drug; Huma | 2000 |
Effects of nitric oxide on matrix metalloproteinase-2 production by rheumatoid synovial cells.
Topics: Arthritis, Rheumatoid; Cell Culture Techniques; Culture Media, Conditioned; Humans; Matrix Metallopr | 2001 |
Gamma glutamyl transpeptidase levels in arthritis: a correlation with clinical and laboratory indices of disease activity.
Topics: Aged; Arthritis, Rheumatoid; Female; gamma-Glutamyltransferase; Humans; Male; Middle Aged; Osteoarth | 1978 |
Bone and joint diseases in the elderly.
Topics: Activities of Daily Living; Adrenal Cortex Hormones; Age Factors; Aged; Anti-Inflammatory Agents; Ar | 1976 |
Drug therapy in the rheumatic diseases.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Gold; Huma | 1992 |
A controlled study of lymphocyte subsets in rheumatoid arthritis.
Topics: Aging; Antineoplastic Agents; Arthritis, Rheumatoid; Gold; Humans; Hydroxychloroquine; Lymphocyte Su | 1992 |
Assessment of kininases in rheumatic diseases and the effect of therapeutic agents.
Topics: Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Bradykini | 1987 |
[Basic therapy of chronic polyarthritis].
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Drug Therapy, Combination; Glucoc | 1987 |
The induction of an erosive arthropathy in the guinea pig with copper II bisglycinate and its treatment with antirheumatic drugs.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Disease Models, Animal; Glycine | 1987 |
Bone loss in rheumatoid arthritis and primary generalized osteoarthrosis: effects of corticosteroids, suppressive antirheumatic drugs and calcium supplements.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Bone Resorption; Calcium; | 1986 |
Use of D-penicillamine in osteoarthrosis.
Topics: Humans; Osteoarthritis; Penicillamine; Pilot Projects | 1985 |
The actionof D-penicillamine on collagen in scleroderma and osteoarthrosis.
Topics: Arthritis, Rheumatoid; Collagen; Humans; In Vitro Techniques; Osteoarthritis; Penicillamine; Sclerod | 1974 |
Joint capsule collagen in osteoarthrosis.
Topics: Adolescent; Adult; Aged; Aging; Cadaver; Child; Child, Preschool; Collagen; Hip Joint; Humans; Hydro | 1973 |