penicillamine has been researched along with Anti-Glomerular Basement Membrane Disease in 15 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
Anti-Glomerular Basement Membrane Disease: An autoimmune disease of the KIDNEY and the LUNG. It is characterized by the presence of circulating autoantibodies targeting the epitopes in the non-collagenous domains of COLLAGEN TYPE IV in the basement membranes of kidney glomeruli (KIDNEY GLOMERULUS) and lung alveoli (PULMONARY ALVEOLI), and the subsequent destruction of these basement membranes. Clinical features include pulmonary alveolar hemorrhage and glomerulonephritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The use of penicillamine in rheumatoid arthritis (RA) is limited by the incidence of adverse effects, some of which are potentially hazardous." | 8.76 | Penicillamine in rheumatoid arthritis: adverse effects. ( Hill, HF, 1979) |
| "A 36-yr-old woman with primary biliary cirrhosis developed a Goodpasture's-like syndrome while on D-penicillamine treatment." | 7.66 | D-Penicillamine-induced Goodpasture's-like syndrome in primary biliary cirrhosis--successful treatment with plasmapheresis and immunosuppressives. ( Kaplan, MM; Matloff, DS, 1980) |
| "The use of penicillamine in rheumatoid arthritis (RA) is limited by the incidence of adverse effects, some of which are potentially hazardous." | 4.76 | Penicillamine in rheumatoid arthritis: adverse effects. ( Hill, HF, 1979) |
| "A 51-year-old woman with advanced rheumatoid arthritis developed a Goodpasture's syndrome during treatment with penicillamine and carbimazole." | 3.67 | Goodpasture's syndrome in a patient receiving penicillamine and carbimazole. ( Alvarez, J; Arboleya, LR; López-Larrea, C; Peces, R; Riera, JR, 1987) |
| " A 35-year-old man who had been taking a low dose of phenytoin for epilepsy presented with nephrotic syndrome and a mesangiocapillary glomerulonephritis." | 3.66 | Plasma exchange in the successful treatment of drug-induced renal disease. ( Short, AI; Swainson, CP; Thomson, D; Winney, RJ, 1982) |
| "A 36-yr-old woman with primary biliary cirrhosis developed a Goodpasture's-like syndrome while on D-penicillamine treatment." | 3.66 | D-Penicillamine-induced Goodpasture's-like syndrome in primary biliary cirrhosis--successful treatment with plasmapheresis and immunosuppressives. ( Kaplan, MM; Matloff, DS, 1980) |
| "Fatal pulmonary hemorrhages and rapidly progressive glomerulonephritis occurred in three patients with Wilson's disease (hepatolenticular degeneration) who had been treated with penicillamine for 2 to 31/2 years." | 3.65 | D-penicillamine induced Goodpasture's syndrome in Wilson's disease. ( Bennett, B; Scheinberg, IH; Sternlieb, I, 1975) |
| "Goodpasture's syndrome is a recognised but rare complication of penicillamine therapy." | 1.26 | Penicillamine-induced "Goodpasture's syndrome": successful treatment of a fulminant case. ( Gavaghan, TE; Hayes, JM; McNaught, PJ; Ralston, M, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (86.67) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Derk, CT | 1 |
| Jimenez, SA | 1 |
| Gavaghan, TE | 1 |
| McNaught, PJ | 1 |
| Ralston, M | 1 |
| Hayes, JM | 1 |
| Camus, P | 1 |
| Swainson, CP | 1 |
| Thomson, D | 1 |
| Short, AI | 1 |
| Winney, RJ | 1 |
| Hasselmann, M | 1 |
| Maurier, F | 1 |
| Lutun, P | 1 |
| Vetter, JM | 1 |
| Tempé, JD | 1 |
| Matloff, DS | 1 |
| Kaplan, MM | 1 |
| Gaskin, G | 1 |
| Thompson, EM | 1 |
| Pusey, CD | 1 |
| Hill, HF | 1 |
| Sternlieb, I | 1 |
| Bennett, B | 1 |
| Scheinberg, IH | 1 |
| Gibson, T | 1 |
| Burry, HC | 1 |
| Ogg, C | 1 |
| Muirden, KD | 1 |
| Meyer, O | 1 |
| Adler, SG | 1 |
| Cohen, AH | 1 |
| Border, WA | 1 |
| Peces, R | 1 |
| Riera, JR | 1 |
| Arboleya, LR | 1 |
| López-Larrea, C | 1 |
| Alvarez, J | 1 |
| Merrill, JP | 1 |
5 reviews available for penicillamine and Anti-Glomerular Basement Membrane Disease
| Article | Year |
|---|---|
[The respiratory complications of D-Penicillamine therapy (author's transl)].
Topics: Anti-Glomerular Basement Membrane Disease; Asthma; Bronchial Diseases; Bronchial Spasm; Female; Huma | 1982 |
Penicillamine in rheumatoid arthritis: adverse effects.
Topics: Anemia, Aplastic; Anti-Glomerular Basement Membrane Disease; Arthritis, Rheumatoid; Bone Marrow; Dru | 1979 |
The use of chloroquine and D-penicillamine in the treatment of rheumatoid arthritis.
Topics: Anti-Glomerular Basement Membrane Disease; Arthritis, Rheumatoid; Captopril; Chloroquine; Clinical T | 1986 |
Hypersensitivity phenomena and the kidney: role of drugs and environmental agents.
Topics: Animals; Anti-Glomerular Basement Membrane Disease; Anti-Inflammatory Agents; Antibodies; Captopril; | 1985 |
Glomerulonephritis (second of three parts).
Topics: Anti-Glomerular Basement Membrane Disease; Cryoglobulins; Drug Hypersensitivity; Endocarditis, Subac | 1974 |
1 trial available for penicillamine and Anti-Glomerular Basement Membrane Disease
| Article | Year |
|---|---|
The use of chloroquine and D-penicillamine in the treatment of rheumatoid arthritis.
Topics: Anti-Glomerular Basement Membrane Disease; Arthritis, Rheumatoid; Captopril; Chloroquine; Clinical T | 1986 |
10 other studies available for penicillamine and Anti-Glomerular Basement Membrane Disease
| Article | Year |
|---|---|
Goodpasture-like syndrome induced by D-penicillamine in a patient with systemic sclerosis: report and review of the literature.
Topics: Aged; Anti-Glomerular Basement Membrane Disease; Antirheumatic Agents; Fatal Outcome; Glomerulonephr | 2003 |
Penicillamine-induced "Goodpasture's syndrome": successful treatment of a fulminant case.
Topics: Anti-Glomerular Basement Membrane Disease; Humans; Immunosuppression Therapy; Kidney; Male; Middle A | 1981 |
Plasma exchange in the successful treatment of drug-induced renal disease.
Topics: Adult; Anti-Glomerular Basement Membrane Disease; Antigen-Antibody Complex; Female; Glomerulonephrit | 1982 |
[Goodpasture's syndrome in rheumatoid arthritis treated with D-penicillamine].
Topics: Anti-Glomerular Basement Membrane Disease; Cyclophosphamide; Female; Humans; Methylprednisolone; Mid | 1982 |
D-Penicillamine-induced Goodpasture's-like syndrome in primary biliary cirrhosis--successful treatment with plasmapheresis and immunosuppressives.
Topics: Adult; Anti-Glomerular Basement Membrane Disease; Azathioprine; Female; Humans; Liver Cirrhosis, Bil | 1980 |
Goodpasture-like syndrome associated with anti-myeloperoxidase antibodies following penicillamine treatment.
Topics: Adult; Anti-Glomerular Basement Membrane Disease; Antibodies, Antineutrophil Cytoplasmic; Antirheuma | 1995 |
D-penicillamine induced Goodpasture's syndrome in Wilson's disease.
Topics: Adult; Anti-Glomerular Basement Membrane Disease; Child; Female; Fluorescent Antibody Technique; Glo | 1975 |
Letter: Goodpasture syndrome and D-penicillamine.
Topics: Anti-Glomerular Basement Membrane Disease; Arthritis, Rheumatoid; Humans; Male; Middle Aged; Penicil | 1976 |
[D-penicillamine: mechanism of cellular action and induced autoimmune diseases].
Topics: Animals; Anti-Glomerular Basement Membrane Disease; Autoimmune Diseases; Dermatomyositis; Humans; Lu | 1986 |
Goodpasture's syndrome in a patient receiving penicillamine and carbimazole.
Topics: Anti-Glomerular Basement Membrane Disease; Arthritis, Rheumatoid; Autoantibodies; Biopsy; Carbimazol | 1987 |