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penicillamine and Anemia, Hypoplastic

penicillamine has been researched along with Anemia, Hypoplastic in 23 studies

Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.

Research Excerpts

ExcerptRelevanceReference
"The use of penicillamine in rheumatoid arthritis (RA) is limited by the incidence of adverse effects, some of which are potentially hazardous."8.76Penicillamine in rheumatoid arthritis: adverse effects. ( Hill, HF, 1979)
"A 65 year old woman with rheumatoid arthritis developed marrow aplasia and jaundice owing to D-penicillamine treatment."7.67Fatal aplastic anaemia and liver toxicity caused by D-penicillamine treatment of rheumatoid arthritis. ( Caspi, D; Fishel, B; Tishler, M; Yaron, M, 1989)
"A 68 year old man with rheumatoid arthritis developed marrow aplasia during D-penicillamine treatment."7.67Acquired sideroblastic anaemia after aplastic anaemia caused by D-penicillamine therapy for rheumatoid arthritis. ( Bijlsma, JW; Dekker, AW; Huber-Bruning, O; Ramselaar, AC, 1987)
"To assess toxicity of D-penicillamine a retrospective chart review was performed on 63 patients with rheumatoid arthritis receiving penicillamine."7.66Toxicity of D-penicillamine in rheumatoid arthritis. A report of 63 patients including two with aplastic anemia and one with the nephrotic syndrome. ( Kammerer, WH; Markenson, JA; Weiss, AS; Weiss, MS, 1978)
"The use of penicillamine in rheumatoid arthritis (RA) is limited by the incidence of adverse effects, some of which are potentially hazardous."4.76Penicillamine in rheumatoid arthritis: adverse effects. ( Hill, HF, 1979)
"A 65 year old woman with rheumatoid arthritis developed marrow aplasia and jaundice owing to D-penicillamine treatment."3.67Fatal aplastic anaemia and liver toxicity caused by D-penicillamine treatment of rheumatoid arthritis. ( Caspi, D; Fishel, B; Tishler, M; Yaron, M, 1989)
"Aplastic anaemia developed in a 33-year-old woman whose rheumatoid arthritis was refractory to the administration of many drugs, including penicillamine and gold."3.67Prolonged remission of severe refractory rheumatoid arthritis following allogeneic bone marrow transplantation for drug-induced aplastic anaemia. ( Jacobs, P; Martell, RW; Vincent, MD, 1986)
"A 68 year old man with rheumatoid arthritis developed marrow aplasia during D-penicillamine treatment."3.67Acquired sideroblastic anaemia after aplastic anaemia caused by D-penicillamine therapy for rheumatoid arthritis. ( Bijlsma, JW; Dekker, AW; Huber-Bruning, O; Ramselaar, AC, 1987)
"To assess toxicity of D-penicillamine a retrospective chart review was performed on 63 patients with rheumatoid arthritis receiving penicillamine."3.66Toxicity of D-penicillamine in rheumatoid arthritis. A report of 63 patients including two with aplastic anemia and one with the nephrotic syndrome. ( Kammerer, WH; Markenson, JA; Weiss, AS; Weiss, MS, 1978)
"Many of the adverse reactions produced by penicillamine and other compounds with an active sulfhydryl group form a distinctive pattern when viewed as a class."2.37Adverse effects profile of sulfhydryl compounds in man. ( Jaffe, IA, 1986)
"Red cell aplasia developed in a case of Wilson's disease following an increase in D-penicillamine dosage after 14 years' treatment."2.35Red cell aplasia following prolonged D-penicillamine therapy. ( Gollan, JL; Hoffbrand, AV; Hussein, S; Sherlock, S, 1976)
"BMT was used to treat severe aplastic anemia which was caused by gold in one case and D-penicillamine in the other."1.29Apparent cure of rheumatoid arthritis by bone marrow transplantation. ( Atkinson, K; Biggs, JC; Cohen, ML; Lowenthal, RM, 1993)
" An overestimation of rare side-effects of drugs should not block the application of certain medicaments, however, they should be given only in such a high dosage as it is necessary."1.26[Hematotoxic lesions caused by non-steroidal antirheumatic agents]. ( Hüge, W; Stobbe, H, 1980)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199019 (82.61)18.7374
1990's2 (8.70)18.2507
2000's2 (8.70)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Suematsu, E1
Miyamura, T1
Idutsu, K1
Minami, R1
Yamamoto, M1
Summerfield, GP1
Bellingham, AJ1
Bunch, C1
Woodrow, JC1
Heimpel, H1
Heit, W1
Stobbe, H1
Hüge, W1
Lowenthal, RM1
Cohen, ML1
Atkinson, K1
Biggs, JC1
Baumelou, E1
Guiguet, M1
Mary, JY1
Kondo, H1
Narita, K1
Richards, AJ1
Velvin, DS1
Whitmore, DN1
Williams, EM1
McAllister, WA1
Vale, JA1
Bourke, B1
Maini, RN1
Griffits, ID1
Scott, JT1
Hill, HF1
Weiss, AS1
Markenson, JA1
Weiss, MS1
Kammerer, WH1
Gollan, JL1
Hussein, S1
Hoffbrand, AV1
Sherlock, S1
Fishel, B1
Tishler, M1
Caspi, D1
Yaron, M1
Jaffe, IA1
Jacobs, P1
Vincent, MD1
Martell, RW1
Ramselaar, AC1
Dekker, AW1
Huber-Bruning, O1
Bijlsma, JW1
Stacher, A1
Lyle, WH1
Bird, ED1
Kjeldsberg, CR1
Ward, HP1

Reviews

5 reviews available for penicillamine and Anemia, Hypoplastic

ArticleYear
[Efficacy of anti-thymocyte globulin and cyclosporin A combined therapy in aplastic anemia complicated with limited cutaneous systemic sclerosis].
    Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology, 2005, Volume: 28, Issue:2

    Topics: Aged; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Female; Granulocyte Colony-Stimulating F

2005
Drug-induced aplastic anaemia: clinical aspects.
    Clinics in haematology, 1980, Volume: 9, Issue:3

    Topics: Adolescent; Adult; Aged; Aging; Anemia, Aplastic; Child; Child, Preschool; Chloramphenicol; Colchici

1980
Penicillamine in rheumatoid arthritis: adverse effects.
    Scandinavian journal of rheumatology. Supplement, 1979, Issue:28

    Topics: Anemia, Aplastic; Anti-Glomerular Basement Membrane Disease; Arthritis, Rheumatoid; Bone Marrow; Dru

1979
Red cell aplasia following prolonged D-penicillamine therapy.
    Journal of clinical pathology, 1976, Volume: 29, Issue:2

    Topics: Adolescent; Adult; Anemia, Aplastic; Bone Marrow; Bone Marrow Cells; Chelating Agents; Child; Child,

1976
Adverse effects profile of sulfhydryl compounds in man.
    The American journal of medicine, 1986, Volume: 80, Issue:3

    Topics: Anemia, Aplastic; Autoimmune Diseases; Captopril; Drug Eruptions; Glomerulonephritis; Humans; Neutro

1986

Other Studies

18 other studies available for penicillamine and Anemia, Hypoplastic

ArticleYear
Successful treatment of chronic cutaneous graft-versus-host-disease (GVHD) with penicillamine.
    Clinical and laboratory haematology, 1983, Volume: 5, Issue:3

    Topics: Adult; Anemia, Aplastic; Bone Marrow Transplantation; Chronic Disease; Cyclophosphamide; Facial Expr

1983
[Hematotoxic lesions caused by non-steroidal antirheumatic agents].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1980, Dec-01, Volume: 35, Issue:23

    Topics: Adult; Aged; Agranulocytosis; Anemia, Aplastic; Arthritis, Rheumatoid; Aspirin; Diclofenac; Female;

1980
Apparent cure of rheumatoid arthritis by bone marrow transplantation.
    The Journal of rheumatology, 1993, Volume: 20, Issue:1

    Topics: Adult; Anemia, Aplastic; Arthritis, Rheumatoid; Bone Marrow Transplantation; Female; Gold; Hand; Hem

1993
Epidemiology of aplastic anemia in France: a case-control study. I. Medical history and medication use. The French Cooperative Group for Epidemiological Study of Aplastic Anemia.
    Blood, 1993, Mar-15, Volume: 81, Issue:6

    Topics: Adolescent; Allopurinol; Anemia, Aplastic; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Ster

1993
Antithymocyte globulin in the treatment of D-penicillamine-induced aplastic anemia.
    International journal of hematology, 2002, Volume: 75, Issue:4

    Topics: Aged; Anemia, Aplastic; Antilymphocyte Serum; Blood Cells; Bone Marrow; Follow-Up Studies; Humans; M

2002
Letter: Fatal aplastic anaemia and D-penicillamine.
    Lancet (London, England), 1976, Mar-20, Volume: 1, Issue:7960

    Topics: Aged; Anemia, Aplastic; Humans; Male; Penicillamine

1976
Letter: Marrow aplasia and penicillamine.
    Lancet (London, England), 1976, Sep-25, Volume: 2, Issue:7987

    Topics: Anemia, Aplastic; Arthritis, Rheumatoid; Bone Marrow; Female; Humans; Middle Aged; Penicillamine; Sc

1976
Fatal marrow aplasia in patient on penicillamine.
    Lancet (London, England), 1976, Sep-18, Volume: 2, Issue:7986

    Topics: Aged; Anemia, Aplastic; Arthritis, Rheumatoid; Female; Humans; Penicillamine

1976
Fatal marrow aplasia in patient on penicillamine.
    Lancet (London, England), 1976, Sep-04, Volume: 1, Issue:7984

    Topics: Anemia, Aplastic; Bone Marrow; Female; Humans; Middle Aged; Penicillamine

1976
Toxicity of D-penicillamine in rheumatoid arthritis. A report of 63 patients including two with aplastic anemia and one with the nephrotic syndrome.
    The American journal of medicine, 1978, Volume: 64, Issue:1

    Topics: Adult; Aged; Anemia, Aplastic; Arthritis, Rheumatoid; Blood Platelets; Female; Humans; Leukocytes; M

1978
Fatal aplastic anaemia and liver toxicity caused by D-penicillamine treatment of rheumatoid arthritis.
    Annals of the rheumatic diseases, 1989, Volume: 48, Issue:7

    Topics: Aged; Anemia, Aplastic; Arthritis, Rheumatoid; Female; Humans; Jaundice; Liver; Penicillamine

1989
Prolonged remission of severe refractory rheumatoid arthritis following allogeneic bone marrow transplantation for drug-induced aplastic anaemia.
    Bone marrow transplantation, 1986, Volume: 1, Issue:2

    Topics: Adult; Anemia, Aplastic; Arthritis, Rheumatoid; Bone Marrow Transplantation; Female; Gold; Humans; P

1986
Acquired sideroblastic anaemia after aplastic anaemia caused by D-penicillamine therapy for rheumatoid arthritis.
    Annals of the rheumatic diseases, 1987, Volume: 46, Issue:2

    Topics: Aged; Anemia, Aplastic; Anemia, Sideroblastic; Arthritis, Rheumatoid; Humans; Male; Penicillamine

1987
[Immunosuppressive therapy in hematology].
    Folia haematologica (Leipzig, Germany : 1928), 1972, Volume: 97, Issue:3

    Topics: Adrenal Cortex Hormones; Adult; Anemia, Aplastic; Anemia, Hemolytic, Autoimmune; Anemia, Myelophthis

1972
Penicillamine in rheumatoid arthritis.
    Lancet (London, England), 1973, Volume: 2, Issue:7822

    Topics: Agranulocytosis; Anemia, Aplastic; Arthritis, Rheumatoid; Humans; Penicillamine

1973
Aplastic anaemia following penicillamine.
    Postgraduate medical journal, 1974, Volume: 50 Suppl 2

    Topics: Anemia, Aplastic; Female; Humans; Huntington Disease; Middle Aged; Penicillamine

1974
Leukemia in arsenic poisoning.
    Annals of internal medicine, 1972, Volume: 77, Issue:6

    Topics: Aged; Anemia, Aplastic; Arsenic; Arsenic Poisoning; Autopsy; Biopsy; Bone Marrow Cells; Cytarabine;

1972
Treatment of lead poisoning.
    The Medical letter on drugs and therapeutics, 1972, Feb-04, Volume: 14, Issue:3

    Topics: Administration, Oral; Adult; Anemia, Aplastic; Chelating Agents; Child; Dimercaprol; Edetic Acid; En

1972