penicillamine has been researched along with Anemia, Aplastic in 23 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
Anemia, Aplastic: A form of anemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The use of penicillamine in rheumatoid arthritis (RA) is limited by the incidence of adverse effects, some of which are potentially hazardous." | 8.76 | Penicillamine in rheumatoid arthritis: adverse effects. ( Hill, HF, 1979) |
| "A 65 year old woman with rheumatoid arthritis developed marrow aplasia and jaundice owing to D-penicillamine treatment." | 7.67 | Fatal aplastic anaemia and liver toxicity caused by D-penicillamine treatment of rheumatoid arthritis. ( Caspi, D; Fishel, B; Tishler, M; Yaron, M, 1989) |
| "A 68 year old man with rheumatoid arthritis developed marrow aplasia during D-penicillamine treatment." | 7.67 | Acquired sideroblastic anaemia after aplastic anaemia caused by D-penicillamine therapy for rheumatoid arthritis. ( Bijlsma, JW; Dekker, AW; Huber-Bruning, O; Ramselaar, AC, 1987) |
| "To assess toxicity of D-penicillamine a retrospective chart review was performed on 63 patients with rheumatoid arthritis receiving penicillamine." | 7.66 | Toxicity of D-penicillamine in rheumatoid arthritis. A report of 63 patients including two with aplastic anemia and one with the nephrotic syndrome. ( Kammerer, WH; Markenson, JA; Weiss, AS; Weiss, MS, 1978) |
| "The use of penicillamine in rheumatoid arthritis (RA) is limited by the incidence of adverse effects, some of which are potentially hazardous." | 4.76 | Penicillamine in rheumatoid arthritis: adverse effects. ( Hill, HF, 1979) |
| "A 65 year old woman with rheumatoid arthritis developed marrow aplasia and jaundice owing to D-penicillamine treatment." | 3.67 | Fatal aplastic anaemia and liver toxicity caused by D-penicillamine treatment of rheumatoid arthritis. ( Caspi, D; Fishel, B; Tishler, M; Yaron, M, 1989) |
| "Aplastic anaemia developed in a 33-year-old woman whose rheumatoid arthritis was refractory to the administration of many drugs, including penicillamine and gold." | 3.67 | Prolonged remission of severe refractory rheumatoid arthritis following allogeneic bone marrow transplantation for drug-induced aplastic anaemia. ( Jacobs, P; Martell, RW; Vincent, MD, 1986) |
| "A 68 year old man with rheumatoid arthritis developed marrow aplasia during D-penicillamine treatment." | 3.67 | Acquired sideroblastic anaemia after aplastic anaemia caused by D-penicillamine therapy for rheumatoid arthritis. ( Bijlsma, JW; Dekker, AW; Huber-Bruning, O; Ramselaar, AC, 1987) |
| "To assess toxicity of D-penicillamine a retrospective chart review was performed on 63 patients with rheumatoid arthritis receiving penicillamine." | 3.66 | Toxicity of D-penicillamine in rheumatoid arthritis. A report of 63 patients including two with aplastic anemia and one with the nephrotic syndrome. ( Kammerer, WH; Markenson, JA; Weiss, AS; Weiss, MS, 1978) |
| "Many of the adverse reactions produced by penicillamine and other compounds with an active sulfhydryl group form a distinctive pattern when viewed as a class." | 2.37 | Adverse effects profile of sulfhydryl compounds in man. ( Jaffe, IA, 1986) |
| "Red cell aplasia developed in a case of Wilson's disease following an increase in D-penicillamine dosage after 14 years' treatment." | 2.35 | Red cell aplasia following prolonged D-penicillamine therapy. ( Gollan, JL; Hoffbrand, AV; Hussein, S; Sherlock, S, 1976) |
| "BMT was used to treat severe aplastic anemia which was caused by gold in one case and D-penicillamine in the other." | 1.29 | Apparent cure of rheumatoid arthritis by bone marrow transplantation. ( Atkinson, K; Biggs, JC; Cohen, ML; Lowenthal, RM, 1993) |
| " An overestimation of rare side-effects of drugs should not block the application of certain medicaments, however, they should be given only in such a high dosage as it is necessary." | 1.26 | [Hematotoxic lesions caused by non-steroidal antirheumatic agents]. ( Hüge, W; Stobbe, H, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (82.61) | 18.7374 |
| 1990's | 2 (8.70) | 18.2507 |
| 2000's | 2 (8.70) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Suematsu, E | 1 |
| Miyamura, T | 1 |
| Idutsu, K | 1 |
| Minami, R | 1 |
| Yamamoto, M | 1 |
| Summerfield, GP | 1 |
| Bellingham, AJ | 1 |
| Bunch, C | 1 |
| Woodrow, JC | 1 |
| Heimpel, H | 1 |
| Heit, W | 1 |
| Stobbe, H | 1 |
| Hüge, W | 1 |
| Lowenthal, RM | 1 |
| Cohen, ML | 1 |
| Atkinson, K | 1 |
| Biggs, JC | 1 |
| Baumelou, E | 1 |
| Guiguet, M | 1 |
| Mary, JY | 1 |
| Kondo, H | 1 |
| Narita, K | 1 |
| Richards, AJ | 1 |
| Velvin, DS | 1 |
| Whitmore, DN | 1 |
| Williams, EM | 1 |
| McAllister, WA | 1 |
| Vale, JA | 1 |
| Bourke, B | 1 |
| Maini, RN | 1 |
| Griffits, ID | 1 |
| Scott, JT | 1 |
| Hill, HF | 1 |
| Weiss, AS | 1 |
| Markenson, JA | 1 |
| Weiss, MS | 1 |
| Kammerer, WH | 1 |
| Gollan, JL | 1 |
| Hussein, S | 1 |
| Hoffbrand, AV | 1 |
| Sherlock, S | 1 |
| Fishel, B | 1 |
| Tishler, M | 1 |
| Caspi, D | 1 |
| Yaron, M | 1 |
| Jaffe, IA | 1 |
| Jacobs, P | 1 |
| Vincent, MD | 1 |
| Martell, RW | 1 |
| Ramselaar, AC | 1 |
| Dekker, AW | 1 |
| Huber-Bruning, O | 1 |
| Bijlsma, JW | 1 |
| Stacher, A | 1 |
| Lyle, WH | 1 |
| Bird, ED | 1 |
| Kjeldsberg, CR | 1 |
| Ward, HP | 1 |
5 reviews available for penicillamine and Anemia, Aplastic
| Article | Year |
|---|---|
[Efficacy of anti-thymocyte globulin and cyclosporin A combined therapy in aplastic anemia complicated with limited cutaneous systemic sclerosis].
Topics: Aged; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Female; Granulocyte Colony-Stimulating F | 2005 |
Drug-induced aplastic anaemia: clinical aspects.
Topics: Adolescent; Adult; Aged; Aging; Anemia, Aplastic; Child; Child, Preschool; Chloramphenicol; Colchici | 1980 |
Penicillamine in rheumatoid arthritis: adverse effects.
Topics: Anemia, Aplastic; Anti-Glomerular Basement Membrane Disease; Arthritis, Rheumatoid; Bone Marrow; Dru | 1979 |
Red cell aplasia following prolonged D-penicillamine therapy.
Topics: Adolescent; Adult; Anemia, Aplastic; Bone Marrow; Bone Marrow Cells; Chelating Agents; Child; Child, | 1976 |
Adverse effects profile of sulfhydryl compounds in man.
Topics: Anemia, Aplastic; Autoimmune Diseases; Captopril; Drug Eruptions; Glomerulonephritis; Humans; Neutro | 1986 |
18 other studies available for penicillamine and Anemia, Aplastic
| Article | Year |
|---|---|
Successful treatment of chronic cutaneous graft-versus-host-disease (GVHD) with penicillamine.
Topics: Adult; Anemia, Aplastic; Bone Marrow Transplantation; Chronic Disease; Cyclophosphamide; Facial Expr | 1983 |
[Hematotoxic lesions caused by non-steroidal antirheumatic agents].
Topics: Adult; Aged; Agranulocytosis; Anemia, Aplastic; Arthritis, Rheumatoid; Aspirin; Diclofenac; Female; | 1980 |
Apparent cure of rheumatoid arthritis by bone marrow transplantation.
Topics: Adult; Anemia, Aplastic; Arthritis, Rheumatoid; Bone Marrow Transplantation; Female; Gold; Hand; Hem | 1993 |
Epidemiology of aplastic anemia in France: a case-control study. I. Medical history and medication use. The French Cooperative Group for Epidemiological Study of Aplastic Anemia.
Topics: Adolescent; Allopurinol; Anemia, Aplastic; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Ster | 1993 |
Antithymocyte globulin in the treatment of D-penicillamine-induced aplastic anemia.
Topics: Aged; Anemia, Aplastic; Antilymphocyte Serum; Blood Cells; Bone Marrow; Follow-Up Studies; Humans; M | 2002 |
Letter: Fatal aplastic anaemia and D-penicillamine.
Topics: Aged; Anemia, Aplastic; Humans; Male; Penicillamine | 1976 |
Letter: Marrow aplasia and penicillamine.
Topics: Anemia, Aplastic; Arthritis, Rheumatoid; Bone Marrow; Female; Humans; Middle Aged; Penicillamine; Sc | 1976 |
Fatal marrow aplasia in patient on penicillamine.
Topics: Aged; Anemia, Aplastic; Arthritis, Rheumatoid; Female; Humans; Penicillamine | 1976 |
Fatal marrow aplasia in patient on penicillamine.
Topics: Anemia, Aplastic; Bone Marrow; Female; Humans; Middle Aged; Penicillamine | 1976 |
Toxicity of D-penicillamine in rheumatoid arthritis. A report of 63 patients including two with aplastic anemia and one with the nephrotic syndrome.
Topics: Adult; Aged; Anemia, Aplastic; Arthritis, Rheumatoid; Blood Platelets; Female; Humans; Leukocytes; M | 1978 |
Fatal aplastic anaemia and liver toxicity caused by D-penicillamine treatment of rheumatoid arthritis.
Topics: Aged; Anemia, Aplastic; Arthritis, Rheumatoid; Female; Humans; Jaundice; Liver; Penicillamine | 1989 |
Prolonged remission of severe refractory rheumatoid arthritis following allogeneic bone marrow transplantation for drug-induced aplastic anaemia.
Topics: Adult; Anemia, Aplastic; Arthritis, Rheumatoid; Bone Marrow Transplantation; Female; Gold; Humans; P | 1986 |
Acquired sideroblastic anaemia after aplastic anaemia caused by D-penicillamine therapy for rheumatoid arthritis.
Topics: Aged; Anemia, Aplastic; Anemia, Sideroblastic; Arthritis, Rheumatoid; Humans; Male; Penicillamine | 1987 |
[Immunosuppressive therapy in hematology].
Topics: Adrenal Cortex Hormones; Adult; Anemia, Aplastic; Anemia, Hemolytic, Autoimmune; Anemia, Myelophthis | 1972 |
Penicillamine in rheumatoid arthritis.
Topics: Agranulocytosis; Anemia, Aplastic; Arthritis, Rheumatoid; Humans; Penicillamine | 1973 |
Aplastic anaemia following penicillamine.
Topics: Anemia, Aplastic; Female; Humans; Huntington Disease; Middle Aged; Penicillamine | 1974 |
Leukemia in arsenic poisoning.
Topics: Aged; Anemia, Aplastic; Arsenic; Arsenic Poisoning; Autopsy; Biopsy; Bone Marrow Cells; Cytarabine; | 1972 |
Treatment of lead poisoning.
Topics: Administration, Oral; Adult; Anemia, Aplastic; Chelating Agents; Child; Dimercaprol; Edetic Acid; En | 1972 |