penicillamine has been researched along with Amyloidosis in 19 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
Amyloidosis: A group of sporadic, familial and/or inherited, degenerative, and infectious disease processes, linked by the common theme of abnormal protein folding and deposition of AMYLOID. As the amyloid deposits enlarge they displace normal tissue structures, causing disruption of function. Various signs and symptoms depend on the location and size of the deposits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "D-penicillamine was used in 2 different doses to treat experimental amyloidosis in mice." | 7.66 | Experimental murine amyloidosis II: effect of penicillamine therapy. ( Hinton, C; Savage, A; Tribe, CR, 1980) |
| " In particular, we describe renal syndromes associated with non-steroidal antiinflammatory drugs, remission-inducing agents (gold and penicillamine) and cytotoxic drugs, secondary amyloidosis, systemic rheumatoid vasculitis, glomerular and tubulo-interstitial nephritis not related to drug therapy." | 4.79 | [Renal damage in rheumatoid arthritis]. ( Bruno, M; Cosseddu, D; Linari, F; Manganaro, M; Pellerito, R; Ravarino, N; Torchio, B; Urbano, D, 1994) |
| "Over a 5-year period 325 patients with rheumatoid arthritis received treatment with gold (162) or D-penicillamine (163)." | 3.66 | Proteinuria in rheumatoid arthritis--drug-induced or amyloid? ( Bourke, BE; Scott, JT; Woodrow, DF, 1981) |
| "D-penicillamine was used in 2 different doses to treat experimental amyloidosis in mice." | 3.66 | Experimental murine amyloidosis II: effect of penicillamine therapy. ( Hinton, C; Savage, A; Tribe, CR, 1980) |
| "The results of electron microscopic examination of renal biopsies from 3 patients with rheumatoid arthritis treated with penicillamine are presented." | 3.66 | Simultaneous occurrence of perimembranous glomerulonephritis and glomerular amyloidosis. ( Bohle, A; Fischbach, H; Gärtner, HV; Helmchen, U; Potjan, K; von Gise, H; Wildhirt, E, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (89.47) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Icardi, A | 1 |
| Araghi, P | 1 |
| Ciabattoni, M | 1 |
| Romano, U | 1 |
| Lazzarini, P | 1 |
| Bianchi, G | 1 |
| Marklund, SL | 1 |
| Ek, B | 1 |
| Steen, L | 1 |
| Bourke, BE | 1 |
| Woodrow, DF | 1 |
| Scott, JT | 1 |
| Savage, A | 1 |
| Hinton, C | 1 |
| Tribe, CR | 1 |
| Manganaro, M | 1 |
| Bruno, M | 1 |
| Ravarino, N | 1 |
| Pellerito, R | 1 |
| Cosseddu, D | 1 |
| Torchio, B | 1 |
| Urbano, D | 1 |
| Linari, F | 1 |
| Kozlowski, H | 1 |
| Hrabowska, M | 1 |
| Corkery, J | 1 |
| Bern, MM | 1 |
| Tullis, JL | 1 |
| Bohle, A | 1 |
| Fischbach, H | 1 |
| Gärtner, HV | 1 |
| von Gise, H | 1 |
| Helmchen, U | 1 |
| Potjan, K | 1 |
| Wildhirt, E | 1 |
| Mancinella, A | 1 |
| Wuchter, J | 1 |
| Schirmeister, J | 1 |
| Cohen, HJ | 2 |
| Missmahl, HP | 1 |
| Willemsen, M | 1 |
| Lessin, LS | 1 |
| Hallal, J | 1 |
| Burkholder, P | 1 |
| Nakano, M | 1 |
| Ozawa, T | 1 |
| Nishi, S | 1 |
| Inomata, A | 1 |
| Satoh, H | 1 |
| Kikuchi, M | 1 |
| Ogino, S | 1 |
| Satoh, T | 1 |
| Suzuki, S | 1 |
| Maruyama, Y | 1 |
| Hill, GS | 1 |
| Lake, B | 1 |
| Andrews, G | 1 |
| Schulz, HJ | 1 |
| Reitzig, P | 1 |
| Lisewski, G | 1 |
| Dietze, F | 1 |
| Wright, JR | 1 |
| Ozdemir, AI | 1 |
| Matsuzaki, M | 1 |
| Binette, P | 1 |
| Calkins, E | 1 |
4 reviews available for penicillamine and Amyloidosis
| Article | Year |
|---|---|
[Kidney involvement in rheumatoid arthritis].
Topics: Amyloidosis; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; A | 2003 |
[Renal damage in rheumatoid arthritis].
Topics: Adult; Amyloidosis; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cyclosporine; Fe | 1994 |
[Current status of the diagnosis and therapy of amyloidosis].
Topics: Amyloidosis; Chloroquine; Folic Acid Antagonists; Glucocorticoids; Gold; Humans; Immunosuppressive A | 1977 |
[Amyloidoses].
Topics: Amyloid; Amyloidosis; Diagnosis, Differential; Immunoglobulins; Melphalan; Penicillamine; Prognosis | 1978 |
15 other studies available for penicillamine and Amyloidosis
| Article | Year |
|---|---|
Effect of long-term penicillamine therapy on erythrocyte CuZn superoxide dismutase activity.
Topics: Adult; Aged; Amyloidosis; Ceruloplasmin; Copper; Erythrocytes; Female; Humans; Male; Middle Aged; Pe | 1984 |
Proteinuria in rheumatoid arthritis--drug-induced or amyloid?
Topics: Adult; Aged; Amyloidosis; Arthritis, Rheumatoid; Gold Sodium Thiomalate; Humans; Kidney Diseases; Ki | 1981 |
Experimental murine amyloidosis II: effect of penicillamine therapy.
Topics: Amyloidosis; Animals; Female; Liver Diseases; Male; Mice; Mice, Inbred CBA; Penicillamine | 1980 |
[Effect of D-penicillamine on the proliferation of reticular cells during the course of experimental amyloidosis].
Topics: Amyloid; Amyloidosis; Animals; Cell Division; Collagen; DNA; Elastic Tissue; Female; Glycosaminoglyc | 1976 |
Resolution of amyloidosis and plasma-cell dyscrasia with combination chemotherapy.
Topics: Amyloidosis; Drug Therapy, Combination; Female; Humans; Melphalan; Middle Aged; Oxymetholone; Parapr | 1978 |
Treatment of primary amyloidosis.
Topics: Amyloidosis; Drug Therapy, Combination; Fluoxymesterone; Humans; Melphalan; Penicillamine; Prednison | 1978 |
Simultaneous occurrence of perimembranous glomerulonephritis and glomerular amyloidosis.
Topics: Amyloidosis; Arthritis, Rheumatoid; Biopsy; Female; Glomerulonephritis; Humans; Kidney; Kidney Disea | 1978 |
Combination chemotherapy for primary amyloidosis reconsidered.
Topics: Amyloidosis; Drug Therapy, Combination; Female; Fluoxymesterone; Follow-Up Studies; Humans; Melphala | 1978 |
[Therapy of amyloidoses].
Topics: Amyloidosis; Azathioprine; Chlorambucil; Colchicine; Humans; Penicillamine | 1977 |
Resolution of primary amyloidosis during chemotherapy. Studies in a patient with nephrotic syndrome.
Topics: Adult; Amyloidosis; Biopsy; Bone Marrow; Bone Marrow Cells; Female; Fluoxymesterone; Humans; Kidney | 1975 |
[Clinicopathological study of renal disorders in patients with rheumatoid arthritis].
Topics: Adolescent; Adult; Aged; Amyloidosis; Arthritis, Rheumatoid; Female; Gold; Humans; Kidney; Kidney Di | 1989 |
Drug-associated glomerulopathies.
Topics: Amyloidosis; Animals; Captopril; Cyclosporins; Disease Models, Animal; Gold; Heroin Dependence; Huma | 1986 |
Rheumatoid arthritis with secondary amyloidosis and malabsorption syndrome. Effect of D-penicillamine.
Topics: Adult; Amyloidosis; Arthritis, Rheumatoid; Digestive System; gamma-Globulins; Hemoglobinometry; Huma | 1968 |
[Malabsorption syndrome and intestinal pseudoobstruction in primary vascular and heart amyloidosis].
Topics: Adult; Amyloidosis; Antibody Formation; Antigen-Antibody Complex; Azathioprine; Chloramphenicol; Cys | 1973 |
Amylod resorption: possible role of multinucleated giant cells. The apparent failure of penicillamine treatment.
Topics: Amyloid; Amyloidosis; Animals; Blood Proteins; Caseins; Cell Nucleus; Disease Models, Animal; Female | 1972 |