penicillamine has been researched along with Agranulocytosis in 17 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
Agranulocytosis: A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).
| Excerpt | Relevance | Reference |
|---|---|---|
| " An overestimation of rare side-effects of drugs should not block the application of certain medicaments, however, they should be given only in such a high dosage as it is necessary." | 1.26 | [Hematotoxic lesions caused by non-steroidal antirheumatic agents]. ( Hüge, W; Stobbe, H, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (88.24) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 1 (5.88) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| CORCOS, JM | 1 |
| SOLER-BECHARA, J | 1 |
| MAYER, K | 1 |
| FREYBERG, RH | 1 |
| GOLDSTEIN, R | 1 |
| JAFFE, I | 1 |
| CRAMER, K | 2 |
| SELANDER, S | 2 |
| Ward, K | 1 |
| Weir, DG | 1 |
| Hoshi, K | 1 |
| Mizushima, Y | 1 |
| Stobbe, H | 1 |
| Hüge, W | 1 |
| Negishi, M | 1 |
| Matsuda, A | 1 |
| Kaga, S | 1 |
| Kanemitsu, H | 1 |
| Hashimoto, M | 1 |
| Kobayashi, K | 1 |
| Ide, H | 1 |
| Yamauchi, Y | 1 |
| Perl, S | 1 |
| Okada, T | 1 |
| Ogawa, K | 1 |
| Eguchi, H | 1 |
| Yabana, T | 1 |
| Hikita, H | 1 |
| Kouno, K | 1 |
| Matsuda, J | 1 |
| Renoux, G | 1 |
| Renoux, M | 1 |
| Guillaumin, JM | 1 |
| Umeki, S | 1 |
| Konishi, Y | 1 |
| Yasuda, T | 1 |
| Morimoto, K | 1 |
| Terao, A | 1 |
| Lyle, WH | 1 |
| Ott, VR | 1 |
| Schmidt, KL | 1 |
| Wallnöfer, H | 1 |
| Hanusch, M | 1 |
| Day, AT | 1 |
| Golding, JR | 1 |
| Lee, PN | 1 |
| Butterworth, AD | 1 |
| Wewalka, F | 1 |
2 reviews available for penicillamine and Agranulocytosis
| Article | Year |
|---|---|
[D-penicillamine-induced immune deficiency].
Topics: Agranulocytosis; Antirheumatic Agents; Humans; Immunologic Deficiency Syndromes; Immunosuppressive A | 2000 |
[Treatment of rheumatoid arthritis using D-penicillamine].
Topics: Adult; Agranulocytosis; Arthritis, Rheumatoid; Biodegradation, Environmental; Female; Humans; Kidney | 1974 |
2 trials available for penicillamine and Agranulocytosis
| Article | Year |
|---|---|
[Treatment of chronic hepatitis with immunosuppressive agents and D-penicillamine].
Topics: Agranulocytosis; Azathioprine; Chronic Disease; Clinical Trials as Topic; Drug Hypersensitivity; Fem | 1973 |
Penicillamine in rheumatoid disease: a long-term study.
Topics: Agranulocytosis; Arthritis, Rheumatoid; Blood Sedimentation; Body Weight; Clinical Trials as Topic; | 1974 |
13 other studies available for penicillamine and Agranulocytosis
| Article | Year |
|---|---|
NEUTROPHILIC AGRANULOCYTOSIS DURING ADMINISTRATION OF PENICILLAMINE.
Topics: Adrenal Cortex Hormones; Agranulocytosis; Arthritis; Arthritis, Rheumatoid; Bone Marrow Examination; | 1964 |
[AGRANULOCYTOSIS TREATED WITH PENICILLAMINE AND ANTAZOLINE].
Topics: Agranulocytosis; Antazoline; Drug Therapy; Histamine H1 Antagonists; Penicillamine | 1965 |
AGRANULOCYTOSIS AFTER PENICILLAMINE AND ANTAZOLINE.
Topics: Agranulocytosis; Antazoline; Anti-Allergic Agents; Drug Therapy; Histamine H1 Antagonists; Humans; L | 1965 |
Life threatening agranulocytosis and toxic epidermal necrolysis during low dose penicillamine therapy.
Topics: Agranulocytosis; Female; Humans; Liver Cirrhosis, Biliary; Middle Aged; Penicillamine; Stevens-Johns | 1981 |
[Agranulocytosis and myasthenia gravis probably induced by D-penicillamine in rheumatoid patients (author's transl)].
Topics: Agranulocytosis; Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Myasthenia Gravis; Penici | 1981 |
[Hematotoxic lesions caused by non-steroidal antirheumatic agents].
Topics: Adult; Aged; Agranulocytosis; Anemia, Aplastic; Arthritis, Rheumatoid; Aspirin; Diclofenac; Female; | 1980 |
[A case of agranulocytosis which occurred several hours after the readministration of D-penicillamine accompanied by shivering-chillness].
Topics: Agranulocytosis; Arthritis, Rheumatoid; Female; Humans; Middle Aged; Penicillamine | 1995 |
Side-effects of long-term D-penicillamine therapy in rheumatoid arthritis.
Topics: Agranulocytosis; Arthritis, Rheumatoid; Drug Eruptions; Female; Humans; Middle Aged; Neutropenia; Pe | 1977 |
[JRA infant of neutrophilic agranulocytosis during administration of D-penicillamine (author's transl)].
Topics: Agranulocytosis; Arthritis, Juvenile; Child; Humans; Male; Neutrophils; Penicillamine | 1979 |
[Effects of prednisone, penicillamine and levamisole on various blood parameters].
Topics: Agranulocytosis; Animals; Antibodies; Erythrocytes; Female; Leukocytes; Levamisole; Mice; Mice, Inbr | 1977 |
D-penicillamine and neutrophilic agranulocytosis.
Topics: Agranulocytosis; Child; Female; Hepatolenticular Degeneration; Humans; Neutropenia; Penicillamine | 1985 |
Penicillamine in rheumatoid arthritis.
Topics: Agranulocytosis; Anemia, Aplastic; Arthritis, Rheumatoid; Humans; Penicillamine | 1973 |
[Wilson's disease. Introduction to current problems (early diagnosis and therapy)].
Topics: Adolescent; Adult; Agranulocytosis; Ceruloplasmin; Child; Copper; Female; Hepatolenticular Degenerat | 1967 |