penicillamine has been researched along with Aging in 30 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to determine whether the protective effects of adenosine on myocardial ischemia-reperfusion injury are altered with age, and if so, to clarify the mechanisms that underlie this change related to nitric oxide (NO) derived from the vascular endothelium." | 7.70 | Mechanism of decreased adenosine protection in reperfusion injury of aging rats. ( Cai, G; Christopher, TA; Friedman, E; Gao, F; Lopez, BL; Ma, XL, 2000) |
| "The purpose of this study was to determine whether the protective effects of adenosine on myocardial ischemia-reperfusion injury are altered with age, and if so, to clarify the mechanisms that underlie this change related to nitric oxide (NO) derived from the vascular endothelium." | 3.70 | Mechanism of decreased adenosine protection in reperfusion injury of aging rats. ( Cai, G; Christopher, TA; Friedman, E; Gao, F; Lopez, BL; Ma, XL, 2000) |
| "The replication of Marek's disease herpesvirus (MDV) and herpesvirus of turkeys (HVT) in chicken embryo fibroblast (CEF) cultures was inhibited by the addition of S-nitroso-N-acetylpenicillamine, a nitric oxide (NO)-generating compound, in a dose-dependent manner." | 1.31 | Inhibitory effects of nitric oxide and gamma interferon on in vitro and in vivo replication of Marek's disease virus. ( Schat, KA; Xing, Z, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (56.67) | 18.7374 |
| 1990's | 6 (20.00) | 18.2507 |
| 2000's | 6 (20.00) | 29.6817 |
| 2010's | 1 (3.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, JJ | 1 |
| Cho, YW | 1 |
| Huh, Y | 1 |
| Cha, CI | 1 |
| Yeo, SG | 1 |
| Fan, X | 1 |
| Xiaoqin, L | 1 |
| Potts, B | 1 |
| Strauch, CM | 1 |
| Nemet, I | 1 |
| Monnier, VM | 1 |
| Adler, A | 1 |
| Messina, E | 1 |
| Sherman, B | 1 |
| Wang, Z | 1 |
| Huang, H | 1 |
| Linke, A | 1 |
| Hintze, TH | 1 |
| Vogel, HG | 3 |
| Oroszlán, G | 2 |
| Lakatos, L | 3 |
| Szabó, L | 2 |
| Matkovics, B | 2 |
| Karmazsin, L | 3 |
| Heimpel, H | 1 |
| Heit, W | 1 |
| Dézsi, Z | 1 |
| Hatvani, I | 1 |
| Trzenschik, K | 1 |
| Lindenhayn, K | 1 |
| Mühlbach, R | 1 |
| Napieralski, P | 1 |
| Noack, K | 1 |
| Vallebuona, F | 1 |
| Raiteri, M | 1 |
| Cernadas, MR | 1 |
| Sánchez de Miguel, L | 1 |
| García-Durán, M | 1 |
| González-Fernández, F | 1 |
| Millás, I | 1 |
| Montón, M | 1 |
| Rodrigo, J | 1 |
| Rico, L | 1 |
| Fernández, P | 1 |
| de Frutos, T | 1 |
| Rodríguez-Feo, JA | 1 |
| Guerra, J | 1 |
| Caramelo, C | 1 |
| Casado, S | 1 |
| Saransaari, P | 1 |
| Oja, SS | 1 |
| Armstead, WM | 1 |
| Chen, L | 1 |
| Daum, G | 1 |
| Fischer, JW | 1 |
| Hawkins, S | 1 |
| Bochaton-Piallat, ML | 1 |
| Gabbiani, G | 1 |
| Clowes, AW | 1 |
| Xing, Z | 1 |
| Schat, KA | 1 |
| Gao, F | 1 |
| Christopher, TA | 1 |
| Lopez, BL | 1 |
| Friedman, E | 1 |
| Cai, G | 1 |
| Ma, XL | 1 |
| Zhang, Q | 1 |
| Molino, B | 1 |
| Yan, L | 1 |
| Haim, T | 1 |
| Vaks, Y | 1 |
| Scholz, PM | 1 |
| Weiss, HR | 1 |
| Prockop, DJ | 1 |
| Kivirikko, KI | 1 |
| Tuderman, L | 1 |
| Guzman, NA | 1 |
| Borkman, RF | 1 |
| Lerman, S | 1 |
| Lovell, CR | 1 |
| Nicholls, AC | 1 |
| Jayson, MI | 2 |
| Bailey, AJ | 2 |
| Hilgner, W | 1 |
| Lindner, J | 1 |
| Schütte, B | 1 |
| Grahame, R | 1 |
| Harvey, W | 1 |
| Caldwell, CW | 1 |
| Bridges, AJ | 1 |
| Walker, SE | 1 |
| Smarr, KL | 1 |
| Reichert, RJ | 1 |
| Anderson, SK | 1 |
| Hewett, JE | 1 |
| Parker, JC | 1 |
| Pearce, WJ | 1 |
| Longo, LD | 1 |
| Verzár, F | 1 |
| Moser, P | 1 |
| Herbert, C | 1 |
| Kormendy, CG | 1 |
| Bender, AD | 1 |
| Deshmukh, A | 1 |
| Deshmukh, K | 1 |
| Nimni, ME | 1 |
3 reviews available for penicillamine and Aging
| Article | Year |
|---|---|
Drug-induced aplastic anaemia: clinical aspects.
Topics: Adolescent; Adult; Aged; Aging; Anemia, Aplastic; Child; Child, Preschool; Chloramphenicol; Colchici | 1980 |
[New viewpoints on the development, maturation, and aging of cataneous connective tissue].
Topics: Aging; Animals; Chick Embryo; Collagen; Connective Tissue; DNA; Elastin; Glycosaminoglycans; Half-Li | 1976 |
Chemical interference with aging.
Topics: Adrenal Cortex Hormones; Aging; Animals; Antioxidants; Appetite Depressants; Autoimmune Diseases; Br | 1971 |
27 other studies available for penicillamine and Aging
| Article | Year |
|---|---|
Effect of nitric oxide on auditory cortical neurons of aged rats.
Topics: Age Factors; Aging; Animals; Auditory Cortex; In Vitro Techniques; Male; Membrane Potentials; NADP; | 2008 |
Topical application of L-arginine blocks advanced glycation by ascorbic acid in the lens of hSVCT2 transgenic mice.
Topics: Acetylcysteine; Administration, Topical; Aging; Animals; Arginine; Ascorbic Acid; Biological Transpo | 2011 |
NAD(P)H oxidase-generated superoxide anion accounts for reduced control of myocardial O2 consumption by NO in old Fischer 344 rats.
Topics: Acetophenones; Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Body Weight; | 2003 |
Influence of desmotropic drugs on viscoelastic properties of rat tail tendons. Hysteresis experiments.
Topics: Aging; Aminoacetonitrile; Animals; Body Weight; Connective Tissue; Elasticity; In Vitro Techniques; | 1984 |
Heme oxygenase activity is decreased by D-penicillamine in neonates.
Topics: Aging; Animals; Animals, Newborn; Heme Oxygenase (Decyclizing); Liver; Male; Mixed Function Oxygenas | 1983 |
Age-related difference in radioprotective effect of D-penicillamine.
Topics: Aging; Animals; Animals, Newborn; Lethal Dose 50; Male; Mice; Penicillamine; Radiation-Protective Ag | 1982 |
Effects of D-penicillamine on some oxidative enzymes of rat organs in vivo.
Topics: Aging; Animals; Catalase; Cytochrome P-450 Enzyme System; Female; Liver; Penicillamine; Peroxidases; | 1981 |
[On the influence of D-penicillamine on collage metabolism - investigations of the rupture of strength in tailfibre in rats of several ages (author's transl)].
Topics: Aging; Animals; Collagen; Models, Biological; Penicillamine; Rats; Tail; Tendons; Tensile Strength | 1980 |
Age-related changes in the NMDA receptor/nitric oxide/cGMP pathway in the hippocampus and cerebellum of freely moving rats subjected to transcerebral microdialysis.
Topics: Aging; Amino Acid Oxidoreductases; Animals; Behavior, Animal; Cerebellum; Cyclic GMP; Extracellular | 1995 |
Expression of constitutive and inducible nitric oxide synthases in the vascular wall of young and aging rats.
Topics: Acetylcholine; Aging; Animals; Aorta; Arginine; Blood Pressure; Bradykinin; Calcium; Cattle; Endothe | 1998 |
Taurine release modified by nitric oxide-generating compounds in the developing and adult mouse hippocampus.
Topics: Aging; Animals; Hippocampus; Hydroxylamine; In Vitro Techniques; Indazoles; Mice; Mice, Inbred Strai | 1999 |
Age-dependent impairment of K(ATP) channel function following brain injury.
Topics: Aging; Animals; Animals, Newborn; Arterioles; Brain; Brain Injuries; Calcitonin Gene-Related Peptide | 1999 |
Loss of expression of the beta subunit of soluble guanylyl cyclase prevents nitric oxide-mediated inhibition of DNA synthesis in smooth muscle cells of old rats.
Topics: Aging; Angioplasty, Balloon; Animals; Aorta; Carotid Artery Injuries; Cells, Cultured; Cyclic GMP; C | 2000 |
Inhibitory effects of nitric oxide and gamma interferon on in vitro and in vivo replication of Marek's disease virus.
Topics: Aging; Animals; Cells, Cultured; Chick Embryo; Chickens; Fibroblasts; Herpesviridae; Herpesvirus 2, | 2000 |
Mechanism of decreased adenosine protection in reperfusion injury of aging rats.
Topics: Adenosine; Aging; Animals; Cardiotonic Agents; Coronary Circulation; Heart; Heart Rate; Hemodynamics | 2000 |
Nitric oxide and cGMP protein kinase activity in aged ventricular myocytes.
Topics: Aging; Alkaloids; Animals; Carbazoles; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Hear | 2001 |
The biosynthesis of collagen and its disorders (second of two parts).
Topics: Aging; Animals; Colchicine; Collagen; Collagen Diseases; Ehlers-Danlos Syndrome; Glucosyltransferase | 1979 |
Evidence for a free radical mechanism in aging and u.v.-irradiated ocular lenses.
Topics: Aging; Animals; Cataract; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Lens, Crystal | 1977 |
Changes in the collagen of synovial membrane in rheumatoid arthritis and effect of D-penicillamine.
Topics: Aged; Aging; Arthritis, Rheumatoid; Collagen; Culture Techniques; Electrophoresis, Polyacrylamide Ge | 1978 |
Influence of age and of desmotropic drugs on the step phenomenon observed in rat skin.
Topics: Aging; Animals; Male; Penicillamine; Prednisolone; Rats; Skin; Skin Physiological Phenomena; Stress, | 1979 |
Strain of rat skin at constant load (creep experiments): influence of age and desmotropic agents.
Topics: Aging; Animals; Female; Male; Penicillamine; Prednisolone; Rats; Skin Physiological Phenomena; Stres | 1977 |
Cutaneous extensibility in health and disease.
Topics: Acromegaly; Adolescent; Adult; Aged; Aging; Child; Child, Preschool; Collagen; Cutis Laxa; Ehlers-Da | 1975 |
A controlled study of lymphocyte subsets in rheumatoid arthritis.
Topics: Aging; Antineoplastic Agents; Arthritis, Rheumatoid; Gold; Humans; Hydroxychloroquine; Lymphocyte Su | 1992 |
Developmental aspects of endothelial function.
Topics: Adenosine Diphosphate; Aging; Animals; Animals, Newborn; Calcimycin; Cerebral Arteries; Cerebrovascu | 1991 |
Influences on the structural stability of collagen in relation to ageing.
Topics: Aging; Animals; Biomechanical Phenomena; Collagen; Connective Tissue; Cysteine; Drug Interactions; F | 1973 |
Joint capsule collagen in osteoarthrosis.
Topics: Adolescent; Adult; Aged; Aging; Cadaver; Child; Child, Preschool; Collagen; Hip Joint; Humans; Hydro | 1973 |
Synthesis of aldehydes and their interactions during the in vitro aging of collagen.
Topics: Acetates; Adipates; Aging; Aldehydes; Amines; Amino Acid Oxidoreductases; Aminopropionitrile; Animal | 1971 |