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penicillamine and Aging

penicillamine has been researched along with Aging in 30 studies

Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"The purpose of this study was to determine whether the protective effects of adenosine on myocardial ischemia-reperfusion injury are altered with age, and if so, to clarify the mechanisms that underlie this change related to nitric oxide (NO) derived from the vascular endothelium."7.70Mechanism of decreased adenosine protection in reperfusion injury of aging rats. ( Cai, G; Christopher, TA; Friedman, E; Gao, F; Lopez, BL; Ma, XL, 2000)
"The purpose of this study was to determine whether the protective effects of adenosine on myocardial ischemia-reperfusion injury are altered with age, and if so, to clarify the mechanisms that underlie this change related to nitric oxide (NO) derived from the vascular endothelium."3.70Mechanism of decreased adenosine protection in reperfusion injury of aging rats. ( Cai, G; Christopher, TA; Friedman, E; Gao, F; Lopez, BL; Ma, XL, 2000)
"The replication of Marek's disease herpesvirus (MDV) and herpesvirus of turkeys (HVT) in chicken embryo fibroblast (CEF) cultures was inhibited by the addition of S-nitroso-N-acetylpenicillamine, a nitric oxide (NO)-generating compound, in a dose-dependent manner."1.31Inhibitory effects of nitric oxide and gamma interferon on in vitro and in vivo replication of Marek's disease virus. ( Schat, KA; Xing, Z, 2000)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199017 (56.67)18.7374
1990's6 (20.00)18.2507
2000's6 (20.00)29.6817
2010's1 (3.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lee, JJ1
Cho, YW1
Huh, Y1
Cha, CI1
Yeo, SG1
Fan, X1
Xiaoqin, L1
Potts, B1
Strauch, CM1
Nemet, I1
Monnier, VM1
Adler, A1
Messina, E1
Sherman, B1
Wang, Z1
Huang, H1
Linke, A1
Hintze, TH1
Vogel, HG3
Oroszlán, G2
Lakatos, L3
Szabó, L2
Matkovics, B2
Karmazsin, L3
Heimpel, H1
Heit, W1
Dézsi, Z1
Hatvani, I1
Trzenschik, K1
Lindenhayn, K1
Mühlbach, R1
Napieralski, P1
Noack, K1
Vallebuona, F1
Raiteri, M1
Cernadas, MR1
Sánchez de Miguel, L1
García-Durán, M1
González-Fernández, F1
Millás, I1
Montón, M1
Rodrigo, J1
Rico, L1
Fernández, P1
de Frutos, T1
Rodríguez-Feo, JA1
Guerra, J1
Caramelo, C1
Casado, S1
Saransaari, P1
Oja, SS1
Armstead, WM1
Chen, L1
Daum, G1
Fischer, JW1
Hawkins, S1
Bochaton-Piallat, ML1
Gabbiani, G1
Clowes, AW1
Xing, Z1
Schat, KA1
Gao, F1
Christopher, TA1
Lopez, BL1
Friedman, E1
Cai, G1
Ma, XL1
Zhang, Q1
Molino, B1
Yan, L1
Haim, T1
Vaks, Y1
Scholz, PM1
Weiss, HR1
Prockop, DJ1
Kivirikko, KI1
Tuderman, L1
Guzman, NA1
Borkman, RF1
Lerman, S1
Lovell, CR1
Nicholls, AC1
Jayson, MI2
Bailey, AJ2
Hilgner, W1
Lindner, J1
Schütte, B1
Grahame, R1
Harvey, W1
Caldwell, CW1
Bridges, AJ1
Walker, SE1
Smarr, KL1
Reichert, RJ1
Anderson, SK1
Hewett, JE1
Parker, JC1
Pearce, WJ1
Longo, LD1
Verzár, F1
Moser, P1
Herbert, C1
Kormendy, CG1
Bender, AD1
Deshmukh, A1
Deshmukh, K1
Nimni, ME1

Reviews

3 reviews available for penicillamine and Aging

ArticleYear
Drug-induced aplastic anaemia: clinical aspects.
    Clinics in haematology, 1980, Volume: 9, Issue:3

    Topics: Adolescent; Adult; Aged; Aging; Anemia, Aplastic; Child; Child, Preschool; Chloramphenicol; Colchici

1980
[New viewpoints on the development, maturation, and aging of cataneous connective tissue].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1976, Volume: 27, Issue:5

    Topics: Aging; Animals; Chick Embryo; Collagen; Connective Tissue; DNA; Elastin; Glycosaminoglycans; Half-Li

1976
Chemical interference with aging.
    Gerontologia, 1971, Volume: 17, Issue:1

    Topics: Adrenal Cortex Hormones; Aging; Animals; Antioxidants; Appetite Depressants; Autoimmune Diseases; Br

1971

Other Studies

27 other studies available for penicillamine and Aging

ArticleYear
Effect of nitric oxide on auditory cortical neurons of aged rats.
    Neuroscience letters, 2008, Dec-05, Volume: 447, Issue:1

    Topics: Age Factors; Aging; Animals; Auditory Cortex; In Vitro Techniques; Male; Membrane Potentials; NADP;

2008
Topical application of L-arginine blocks advanced glycation by ascorbic acid in the lens of hSVCT2 transgenic mice.
    Molecular vision, 2011, Volume: 17

    Topics: Acetylcysteine; Administration, Topical; Aging; Animals; Arginine; Ascorbic Acid; Biological Transpo

2011
NAD(P)H oxidase-generated superoxide anion accounts for reduced control of myocardial O2 consumption by NO in old Fischer 344 rats.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 285, Issue:3

    Topics: Acetophenones; Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Body Weight;

2003
Influence of desmotropic drugs on viscoelastic properties of rat tail tendons. Hysteresis experiments.
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:2

    Topics: Aging; Aminoacetonitrile; Animals; Body Weight; Connective Tissue; Elasticity; In Vitro Techniques;

1984
Heme oxygenase activity is decreased by D-penicillamine in neonates.
    Experientia, 1983, Aug-15, Volume: 39, Issue:8

    Topics: Aging; Animals; Animals, Newborn; Heme Oxygenase (Decyclizing); Liver; Male; Mixed Function Oxygenas

1983
Age-related difference in radioprotective effect of D-penicillamine.
    Developmental pharmacology and therapeutics, 1982, Volume: 5, Issue:3-4

    Topics: Aging; Animals; Animals, Newborn; Lethal Dose 50; Male; Mice; Penicillamine; Radiation-Protective Ag

1982
Effects of D-penicillamine on some oxidative enzymes of rat organs in vivo.
    Experientia, 1981, Jan-15, Volume: 37, Issue:1

    Topics: Aging; Animals; Catalase; Cytochrome P-450 Enzyme System; Female; Liver; Penicillamine; Peroxidases;

1981
[On the influence of D-penicillamine on collage metabolism - investigations of the rupture of strength in tailfibre in rats of several ages (author's transl)].
    Zeitschrift fur Alternsforschung, 1980, Volume: 35, Issue:4

    Topics: Aging; Animals; Collagen; Models, Biological; Penicillamine; Rats; Tail; Tendons; Tensile Strength

1980
Age-related changes in the NMDA receptor/nitric oxide/cGMP pathway in the hippocampus and cerebellum of freely moving rats subjected to transcerebral microdialysis.
    The European journal of neuroscience, 1995, Apr-01, Volume: 7, Issue:4

    Topics: Aging; Amino Acid Oxidoreductases; Animals; Behavior, Animal; Cerebellum; Cyclic GMP; Extracellular

1995
Expression of constitutive and inducible nitric oxide synthases in the vascular wall of young and aging rats.
    Circulation research, 1998, Aug-10, Volume: 83, Issue:3

    Topics: Acetylcholine; Aging; Animals; Aorta; Arginine; Blood Pressure; Bradykinin; Calcium; Cattle; Endothe

1998
Taurine release modified by nitric oxide-generating compounds in the developing and adult mouse hippocampus.
    Neuroscience, 1999, Volume: 89, Issue:4

    Topics: Aging; Animals; Hippocampus; Hydroxylamine; In Vitro Techniques; Indazoles; Mice; Mice, Inbred Strai

1999
Age-dependent impairment of K(ATP) channel function following brain injury.
    Journal of neurotrauma, 1999, Volume: 16, Issue:5

    Topics: Aging; Animals; Animals, Newborn; Arterioles; Brain; Brain Injuries; Calcitonin Gene-Related Peptide

1999
Loss of expression of the beta subunit of soluble guanylyl cyclase prevents nitric oxide-mediated inhibition of DNA synthesis in smooth muscle cells of old rats.
    Circulation research, 2000, Mar-17, Volume: 86, Issue:5

    Topics: Aging; Angioplasty, Balloon; Animals; Aorta; Carotid Artery Injuries; Cells, Cultured; Cyclic GMP; C

2000
Inhibitory effects of nitric oxide and gamma interferon on in vitro and in vivo replication of Marek's disease virus.
    Journal of virology, 2000, Volume: 74, Issue:8

    Topics: Aging; Animals; Cells, Cultured; Chick Embryo; Chickens; Fibroblasts; Herpesviridae; Herpesvirus 2,

2000
Mechanism of decreased adenosine protection in reperfusion injury of aging rats.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:1

    Topics: Adenosine; Aging; Animals; Cardiotonic Agents; Coronary Circulation; Heart; Heart Rate; Hemodynamics

2000
Nitric oxide and cGMP protein kinase activity in aged ventricular myocytes.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 281, Issue:6

    Topics: Aging; Alkaloids; Animals; Carbazoles; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Hear

2001
The biosynthesis of collagen and its disorders (second of two parts).
    The New England journal of medicine, 1979, Jul-12, Volume: 301, Issue:2

    Topics: Aging; Animals; Colchicine; Collagen; Collagen Diseases; Ehlers-Danlos Syndrome; Glucosyltransferase

1979
Evidence for a free radical mechanism in aging and u.v.-irradiated ocular lenses.
    Experimental eye research, 1977, Volume: 25, Issue:3

    Topics: Aging; Animals; Cataract; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Lens, Crystal

1977
Changes in the collagen of synovial membrane in rheumatoid arthritis and effect of D-penicillamine.
    Clinical science and molecular medicine, 1978, Volume: 55, Issue:1

    Topics: Aged; Aging; Arthritis, Rheumatoid; Collagen; Culture Techniques; Electrophoresis, Polyacrylamide Ge

1978
Influence of age and of desmotropic drugs on the step phenomenon observed in rat skin.
    Archives of dermatological research, 1979, Mar-31, Volume: 264, Issue:2

    Topics: Aging; Animals; Male; Penicillamine; Prednisolone; Rats; Skin; Skin Physiological Phenomena; Stress,

1979
Strain of rat skin at constant load (creep experiments): influence of age and desmotropic agents.
    Gerontology, 1977, Volume: 23, Issue:2

    Topics: Aging; Animals; Female; Male; Penicillamine; Prednisolone; Rats; Skin Physiological Phenomena; Stres

1977
Cutaneous extensibility in health and disease.
    Rheumatology and rehabilitation, 1975, Volume: 14, Issue:2

    Topics: Acromegaly; Adolescent; Adult; Aged; Aging; Child; Child, Preschool; Collagen; Cutis Laxa; Ehlers-Da

1975
A controlled study of lymphocyte subsets in rheumatoid arthritis.
    Clinical immunology and immunopathology, 1992, Volume: 63, Issue:3

    Topics: Aging; Antineoplastic Agents; Arthritis, Rheumatoid; Gold; Humans; Hydroxychloroquine; Lymphocyte Su

1992
Developmental aspects of endothelial function.
    Seminars in perinatology, 1991, Volume: 15, Issue:1

    Topics: Adenosine Diphosphate; Aging; Animals; Animals, Newborn; Calcimycin; Cerebral Arteries; Cerebrovascu

1991
Influences on the structural stability of collagen in relation to ageing.
    Gerontologia, 1973, Volume: 19, Issue:3

    Topics: Aging; Animals; Biomechanical Phenomena; Collagen; Connective Tissue; Cysteine; Drug Interactions; F

1973
Joint capsule collagen in osteoarthrosis.
    Annals of the rheumatic diseases, 1973, Volume: 32, Issue:6

    Topics: Adolescent; Adult; Aged; Aging; Cadaver; Child; Child, Preschool; Collagen; Hip Joint; Humans; Hydro

1973
Synthesis of aldehydes and their interactions during the in vitro aging of collagen.
    Biochemistry, 1971, Jun-08, Volume: 10, Issue:12

    Topics: Acetates; Adipates; Aging; Aldehydes; Amines; Amino Acid Oxidoreductases; Aminopropionitrile; Animal

1971