penicillamine has been researched along with Adverse Drug Event in 23 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate medical treatments, in terms of adverse events (AEs) and therapeutic goals, in a large series of patients with cystinuria." | 1.51 | Adverse events associated with currently used medical treatments for cystinuria and treatment goals: results from a series of 442 patients in France. ( Bataille, P; Bridoux, F; Brignon, P; Choquenet, C; Cochat, P; Combe, C; Conort, P; Courbebaisse, M; Daudon, M; Decramer, S; Doré, B; Dussol, B; Essig, M; Friedlander, G; Frimat, M; Gaunez, N; Jais, JP; Joly, D; Knebelmann, B; Le Toquin-Bernard, S; Lebbah, S; Lillo-Le Louët, A; Méjean, A; Meria, P; Morin, D; N'Guyen, HV; Normand, M; Pietak, M; Pontoizeau, C; Prot-Bertoye, C; Ronco, P; Saussine, C; Tostivint, I; Traxer, O; Tsimaratos, M, 2019) |
| "We retrospectively analyzed 235 Wilson disease patients." | 1.43 | Concomitant immune-related events in Wilson disease: implications for monitoring chelator therapy. ( Ferenci, P; Gohdes, A; Gotthardt, DN; Pfeiffenberger, J; Schäfer, M; Seessle, J; Stremmel, W; Weiss, KH, 2016) |
| " Chelator-based treatment regimens were analyzed for their effect on neurologic and hepatic symptoms and for adverse events that led to discontinuation of therapy (Kaplan-Meier estimation; data were collected for a mean of 13." | 1.39 | Efficacy and safety of oral chelators in treatment of patients with Wilson disease. ( Ferenci, P; Ferenci-Foerster, D; Gotthardt, DN; Hefter, H; Houwen, RH; Maieron, A; Merle, U; Reuner, U; Schäfer, M; Schmidt, HH; Stauber, R; Stremmel, W; Teufel, U; Thurik, F; Trocello, JM; Weiss, KH; Wiegand, F; Zoller, H, 2013) |
| " We proposed a systematic classification scheme using FDA-approved drug labeling to assess the DILI potential of drugs, which yielded a benchmark dataset with 287 drugs representing a wide range of therapeutic categories and daily dosage amounts." | 1.37 | FDA-approved drug labeling for the study of drug-induced liver injury. ( Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V, 2011) |
| "5 million adverse drug reaction (ADR) reports for 8620 drugs/biologics that are listed for 1191 Coding Symbols for Thesaurus of Adverse Reaction (COSTAR) terms of adverse effects." | 1.32 | Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. ( Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (34.78) | 18.7374 |
| 1990's | 2 (8.70) | 18.2507 |
| 2000's | 3 (13.04) | 29.6817 |
| 2010's | 9 (39.13) | 24.3611 |
| 2020's | 1 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| Matthews, EJ | 1 |
| Kruhlak, NL | 1 |
| Weaver, JL | 1 |
| Benz, RD | 1 |
| Contrera, JF | 1 |
| Chen, M | 1 |
| Vijay, V | 1 |
| Shi, Q | 2 |
| Liu, Z | 2 |
| Fang, H | 2 |
| Tong, W | 2 |
| Dawson, S | 1 |
| Stahl, S | 1 |
| Paul, N | 1 |
| Barber, J | 1 |
| Kenna, JG | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Morgan, RE | 1 |
| van Staden, CJ | 1 |
| Chen, Y | 1 |
| Kalyanaraman, N | 1 |
| Kalanzi, J | 1 |
| Dunn, RT | 1 |
| Afshari, CA | 1 |
| Hamadeh, HK | 1 |
| Ghaedi, F | 1 |
| Etesami, I | 1 |
| Aryanian, Z | 1 |
| Kalantari, Y | 1 |
| Goodarzi, A | 1 |
| Teymourpour, A | 1 |
| Tavakolpour, S | 1 |
| Mahmoudi, H | 1 |
| Daneshpazhooh, M | 1 |
| Prot-Bertoye, C | 1 |
| Lebbah, S | 1 |
| Daudon, M | 1 |
| Tostivint, I | 1 |
| Jais, JP | 1 |
| Lillo-Le Louët, A | 1 |
| Pontoizeau, C | 1 |
| Cochat, P | 1 |
| Bataille, P | 1 |
| Bridoux, F | 1 |
| Brignon, P | 1 |
| Choquenet, C | 1 |
| Combe, C | 1 |
| Conort, P | 1 |
| Decramer, S | 1 |
| Doré, B | 1 |
| Dussol, B | 1 |
| Essig, M | 1 |
| Frimat, M | 1 |
| Gaunez, N | 1 |
| Joly, D | 1 |
| Le Toquin-Bernard, S | 1 |
| Méjean, A | 1 |
| Meria, P | 1 |
| Morin, D | 1 |
| N'Guyen, HV | 1 |
| Normand, M | 1 |
| Pietak, M | 1 |
| Ronco, P | 1 |
| Saussine, C | 1 |
| Tsimaratos, M | 1 |
| Friedlander, G | 1 |
| Traxer, O | 1 |
| Knebelmann, B | 1 |
| Courbebaisse, M | 1 |
| Weiss, KH | 2 |
| Thurik, F | 1 |
| Gotthardt, DN | 2 |
| Schäfer, M | 2 |
| Teufel, U | 1 |
| Wiegand, F | 1 |
| Merle, U | 1 |
| Ferenci-Foerster, D | 1 |
| Maieron, A | 1 |
| Stauber, R | 1 |
| Zoller, H | 1 |
| Schmidt, HH | 1 |
| Reuner, U | 1 |
| Hefter, H | 1 |
| Trocello, JM | 1 |
| Houwen, RH | 1 |
| Ferenci, P | 2 |
| Stremmel, W | 2 |
| Metushi, IG | 1 |
| Zhu, X | 1 |
| Uetrecht, J | 1 |
| Chabra, IS | 1 |
| Grandinetti, LM | 1 |
| Seessle, J | 1 |
| Gohdes, A | 1 |
| Pfeiffenberger, J | 1 |
| Shenton, JM | 1 |
| Chen, J | 1 |
| Uetrecht, JP | 1 |
| Thiele, KG | 1 |
| Muehrcke, RC | 1 |
| Berning, H | 1 |
| Matthes, KJ | 1 |
| Mattila, MJ | 1 |
| Elston, DM | 1 |
| Argov, Z | 1 |
| Mastaglia, FL | 1 |
| Schwarz, JA | 1 |
| Bourgeois, P | 1 |
| Aeschlimann, A | 1 |
| White, JP | 1 |
| Ward, MJ | 1 |
| Byron, MA | 1 |
| Harpey, JP | 1 |
| Leibold, JE | 1 |
7 reviews available for penicillamine and Adverse Drug Event
| Article | Year |
|---|---|
Drug-induced pemphigus: A systematic review of 170 patients.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Antirheumatic Agents; Captopril; C | 2021 |
[Drug induced pulmonary symptoms in medicine].
Topics: Amiodarone; Amphotericin B; Bronchoconstriction; Drug-Related Side Effects and Adverse Reactions; Fe | 1996 |
Drug therapy: Disorders of neuromuscular transmission caused by drugs.
Topics: Aged; Animals; Anti-Bacterial Agents; Anticonvulsants; Cardiovascular Agents; Chloroquine; Drug-Rela | 1979 |
Drug-induced scleroderma.
Topics: Amphetamine; Bleomycin; Cocaine; Diethylpropion; Drug-Related Side Effects and Adverse Reactions; Hu | 1991 |
Drug-induced adverse pulmonary reactions.
Topics: Amiodarone; Asthma; Bleomycin; Carmustine; Drug-Related Side Effects and Adverse Reactions; Gold; Hu | 1985 |
Lupus-like syndromes induced by drugs.
Topics: Antibodies, Antinuclear; Antibody Formation; Arthritis, Rheumatoid; Chlorpromazine; DNA, Single-Stra | 1974 |
Drugs having a toxic effect on the optic nerve.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anti-Infective Agents; Contraceptives, Oral; Digitalis G | 1971 |
16 other studies available for penicillamine and Adverse Drug Event
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Dru | 2004 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Des | 2011 |
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2012 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2013 |
Adverse events associated with currently used medical treatments for cystinuria and treatment goals: results from a series of 442 patients in France.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Cystinuria; Drug-Related Side Effects and Adverse | 2019 |
Efficacy and safety of oral chelators in treatment of patients with Wilson disease.
Topics: Adolescent; Adult; Austria; Chelating Agents; Child; Child, Preschool; Cohort Studies; Drug-Related | 2013 |
D-penicillamine-induced granulomatous hepatitis in brown Norway rats.
Topics: Alanine Transaminase; Animals; Autoimmune Diseases; CD8-Positive T-Lymphocytes; Chemical and Drug In | 2014 |
Asymptomatic annular plaques on the neck.
Topics: Adult; Antirheumatic Agents; Biopsy; Drug-Related Side Effects and Adverse Reactions; Female; Humans | 2014 |
Concomitant immune-related events in Wilson disease: implications for monitoring chelator therapy.
Topics: Adolescent; Adult; Antibodies, Antinuclear; Autoimmune Diseases; Chelating Agents; Child; Cross-Sect | 2016 |
Animal models of idiosyncratic drug reactions.
Topics: Adverse Drug Reaction Reporting Systems; Animals; Autoimmune Diseases; Drug-Related Side Effects and | 2004 |
[Kidney diseases caused by drugs].
Topics: Acute Kidney Injury; Adult; Anemia; Arthritis, Rheumatoid; Dextrans; Drug-Related Side Effects and A | 1967 |
Drug-induced proteinuria.
Topics: Drug-Related Side Effects and Adverse Reactions; Female; Humans; Kidney; Kidney Diseases; Kidney Tub | 1981 |
Photo quiz. Drug-induced pemphigus foliaceus.
Topics: Angiotensin-Converting Enzyme Inhibitors; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Stero | 2000 |
[Drug-induced disorders of lupus erythematosus type (author's transl)].
Topics: Animals; Antibody Formation; Anticonvulsants; Chlorpromazine; Drug-Related Side Effects and Adverse | 1977 |
Treatment of rheumatic diseases.
Topics: Abnormalities, Drug-Induced; Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Breast Feeding; | 1987 |