penicillamine has been researched along with Acute Hepatic Failure in 9 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Consideration of a diagnosis of Wilson disease is still the critical factor in testing for and establishing disease diagnosis." | 2.55 | Wilson Disease: Diagnosis, Treatment, and Follow-up. ( Schilsky, ML, 2017) |
| "Four patients presented with acute liver failure, four with persistently elevated liver function tests, and two with decompensated cirrhosis; none had neurological manifestations." | 1.48 | Hepatic manifestations of Wilson's disease: 12-year experience in a Swiss tertiary referral centre. ( Ferenci, P; Fraga, M; Giostra, E; Hiroz, P; Moradpour, D; Saldarriaga, J; Sempoux, C; Vieira Barbosa, J, 2018) |
| "We conclude that Wilson's disease may be a good indication for LTX for both neurological manifestation with stable liver function and hepatic manifestation with cirrhosis or acute liver failure." | 1.30 | Liver transplantation: treatment of choice for hepatic and neurological manifestation of Wilson's disease. ( Bechstein, WO; Becker, M; Luck, W; Mueller, AR; Neuhaus, P; Neuhaus, R; Platz, KP; Schuelke, M; Schumacher, G; Steinmüller, T, 1997) |
| "In child B acute liver failure developed despite initiation of treatment." | 1.30 | Treatment of copper associated liver disease in childhood. ( Kardoff, R; Melter, M; Rodeck, B, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Proost, R | 1 |
| Cassiman, D | 1 |
| Levtchenko, E | 1 |
| Morava-Kozicz, E | 1 |
| Neirynck, J | 1 |
| Witters, P | 1 |
| Schilsky, ML | 1 |
| Damsgaard, J | 1 |
| Larsen, FS | 1 |
| Ytting, H | 1 |
| Vieira Barbosa, J | 1 |
| Fraga, M | 1 |
| Saldarriaga, J | 1 |
| Hiroz, P | 1 |
| Giostra, E | 1 |
| Sempoux, C | 1 |
| Ferenci, P | 1 |
| Moradpour, D | 1 |
| Oosthuizen, NM | 1 |
| Rodríguez Fariña, E | 1 |
| Tremosa Llurba, G | 1 |
| Xiol Quingles, X | 1 |
| Lores Obradors, A | 1 |
| Castellote Alonso, J | 1 |
| Gornals Soler, JB | 1 |
| López Núñez, C | 1 |
| Schumacher, G | 1 |
| Platz, KP | 1 |
| Mueller, AR | 1 |
| Neuhaus, R | 1 |
| Steinmüller, T | 1 |
| Bechstein, WO | 1 |
| Becker, M | 1 |
| Luck, W | 1 |
| Schuelke, M | 1 |
| Neuhaus, P | 1 |
| Rodeck, B | 1 |
| Kardoff, R | 1 |
| Melter, M | 1 |
| Takahashi, A | 1 |
| Suzuki, T | 1 |
| Shishido, S | 1 |
| Tojo, J | 1 |
| Ito, O | 1 |
| Kazuta, Y | 1 |
| Watanabe, H | 1 |
| Ishikawa, H | 1 |
| Ohira, H | 1 |
| Obara, K | 1 |
| Kasukawa, R | 1 |
2 reviews available for penicillamine and Acute Hepatic Failure
| Article | Year |
|---|---|
Fulminant Wilson Disease in Children: Recovery After Plasma Exchange Without Transplantation.
Topics: Adolescent; Child; Female; Hepatolenticular Degeneration; Humans; Liver Failure, Acute; Liver Transp | 2020 |
Wilson Disease: Diagnosis, Treatment, and Follow-up.
Topics: Aftercare; Biopsy; Ceruloplasmin; Chelating Agents; Copper; Copper-Transporting ATPases; Disease Man | 2017 |
7 other studies available for penicillamine and Acute Hepatic Failure
| Article | Year |
|---|---|
Reversal of Acute Liver Failure Due to Wilson Disease by a Regimen of High-Volume Plasma Exchange and Penicillamine.
Topics: Adult; Chelating Agents; Hepatolenticular Degeneration; Humans; Liver Failure, Acute; Male; Penicill | 2019 |
Hepatic manifestations of Wilson's disease: 12-year experience in a Swiss tertiary referral centre.
Topics: Adult; Chelating Agents; Copper; Copper-Transporting ATPases; Female; Hepatolenticular Degeneration; | 2018 |
Undetectable serum alkaline phosphatase activity in a patient with fulminant hepatic failure and hemolytic anemia.
Topics: Adult; Alkaline Phosphatase; Anemia, Hemolytic; Chelating Agents; Copper; Diagnosis, Differential; F | 2011 |
D-penicillamine and plasmapheresis in acute liver failure secondary to Wilson's disease.
Topics: Adult; Anemia, Hemolytic; Biopsy; Ceruloplasmin; Chelating Agents; Copper; Female; Follow-Up Studies | 2003 |
Liver transplantation: treatment of choice for hepatic and neurological manifestation of Wilson's disease.
Topics: Adolescent; Adult; Anemia, Hemolytic; Ataxia; Chelating Agents; Deglutition Disorders; Dysarthria; D | 1997 |
Treatment of copper associated liver disease in childhood.
Topics: Chelating Agents; Chemical and Drug Induced Liver Injury; Copper; Drinking; Germany; Humans; Infant; | 1999 |
[Two recovery cases of Wilson's disease initiated with severe hemolysis and acute hepatic failure].
Topics: Adolescent; Anemia, Hemolytic; Chelating Agents; Female; Hepatolenticular Degeneration; Humans; Live | 2000 |