penicillamine has been researched along with Acantholysis in 8 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
Acantholysis: Separation of the prickle cells of the stratum spinosum of the epidermis, resulting in atrophy of the prickle cell layer. It is seen in diseases such as pemphigus vulgaris (see PEMPHIGUS) and DARIER DISEASE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The incubation of cultured epidermal cells with IgG obtained from a 56-year-old man with penicillamine-induced pemphigus resulted in an increase in extracellular and intracellular plasminogen activator." | 7.67 | Penicillamine-induced pemphigus. Immunoglobulin from this patient induces plasminogen activator synthesis by human epidermal cells in culture: mechanism for acantholysis in pemphigus. ( Hashimoto, K; Lazarus, GS; Singer, K, 1984) |
| ", penicillamine, captopril, thiopronine) can induce pemphigus in vivo and provoke acantholysis in vitro." | 3.68 | Enalapril: a powerful in vitro non-thiol acantholytic agent. ( de Angelis, E; Grassi, M; Lombardi, ML; Ruocco, V, 1992) |
| "The incubation of cultured epidermal cells with IgG obtained from a 56-year-old man with penicillamine-induced pemphigus resulted in an increase in extracellular and intracellular plasminogen activator." | 3.67 | Penicillamine-induced pemphigus. Immunoglobulin from this patient induces plasminogen activator synthesis by human epidermal cells in culture: mechanism for acantholysis in pemphigus. ( Hashimoto, K; Lazarus, GS; Singer, K, 1984) |
| "Pemphigus is an autoimmune intraepidermal bullous disease involving the skin and mucous membranes." | 2.36 | Pemphigus: current concepts. ( , 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (37.50) | 18.7374 |
| 1990's | 5 (62.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hashimoto, K | 1 |
| Singer, K | 1 |
| Lazarus, GS | 1 |
| Lombardi, ML | 3 |
| de Angelis, E | 3 |
| Rossano, F | 1 |
| Ruocco, V | 3 |
| Zvulunov, A | 1 |
| Grunwald, MH | 1 |
| Avinoach, I | 1 |
| Halevy, S | 1 |
| Grassi, M | 1 |
| De Dobbeleer, G | 1 |
| Godfrine, S | 1 |
| Gourdain, JM | 1 |
| De Graef, C | 1 |
| Heenen, M | 1 |
| Pisani, M | 1 |
| Yokel, BK | 1 |
| Hood, AF | 1 |
| Anhalt, GJ | 1 |
1 review available for penicillamine and Acantholysis
| Article | Year |
|---|---|
Pemphigus: current concepts.
Topics: Acantholysis; Adrenal Cortex Hormones; Autoimmune Diseases; Binding Sites, Antibody; Gold; Humans; I | 1980 |
7 other studies available for penicillamine and Acantholysis
| Article | Year |
|---|---|
Penicillamine-induced pemphigus. Immunoglobulin from this patient induces plasminogen activator synthesis by human epidermal cells in culture: mechanism for acantholysis in pemphigus.
Topics: Acantholysis; Cells, Cultured; Epidermis; Humans; Immunoglobulin G; Male; Middle Aged; Pemphigus; Pe | 1984 |
Imbalance between plasminogen activator and its inhibitors in thiol-induced acantholysis.
Topics: Acantholysis; Captopril; Culture Media; Culture Techniques; Epidermis; Humans; Penicillamine; Plasmi | 1993 |
Transient acantholytic dermatosis (Grover's disease) in a patient with progressive systemic sclerosis treated with D-penicillamine.
Topics: Acantholysis; Antirheumatic Agents; Chelating Agents; Female; Humans; Middle Aged; Penicillamine; Sc | 1997 |
Enalapril: a powerful in vitro non-thiol acantholytic agent.
Topics: Acantholysis; Captopril; Culture Techniques; Enalapril; Female; Humans; Immunoglobulin G; Penicillam | 1992 |
In vitro acantholysis induced by D-penicillamine, captopril, and piroxicam on dead de-epidermized dermis.
Topics: Acantholysis; Captopril; Cell Death; Cells, Cultured; Epidermis; Humans; Keratinocytes; Microscopy, | 1992 |
Biochemical acantholysis provoked by thiol drugs.
Topics: Acantholysis; Captopril; Humans; Pemphigus; Penicillamine; Skin Diseases; Sulfhydryl Compounds; Tiop | 1990 |
Induction of acantholysis in organ explant culture by penicillamine and captopril.
Topics: Acantholysis; Adult; Captopril; Dose-Response Relationship, Drug; Humans; Infant, Newborn; Organ Cul | 1989 |