pemoline has been researched along with Tourette Syndrome in 10 studies
Pemoline: A central nervous system stimulant used in fatigue and depressive states and to treat hyperkinetic disorders in children.
pemoline : A member of the class of 1,3-oxazoles that is 1,3-oxazol-4(5H)-one which is substituted by an amino group at position 2 and by a phenyl group at position 5. A central nervous system stimulant, it was used to treat hyperactivity disorders in children, but withdrawn from use following reports of serious hepatotoxicity.
Tourette Syndrome: A neuropsychological disorder related to alterations in DOPAMINE metabolism and neurotransmission involving frontal-subcortical neuronal circuits. Both multiple motor and one or more vocal tics need to be present with TICS occurring many times a day, nearly daily, over a period of more than one year. The onset is before age 18 and the disturbance is not due to direct physiological effects of a substance or another medical condition. The disturbance causes marked distress or significant impairment in social, occupational, or other important areas of functioning. (From DSM-IV, 1994; Neurol Clin 1997 May;15(2):357-79)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gilles de la Tourette syndrome is frequently associated with symptoms characteristic of hyperactivity and often goes unrecognized for long periods of time." | 1.26 | Deleterious effects of drugs used for hyperactivity on patients with Gilles de la Tourette syndrome. ( Sleator, EK, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (80.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bonthala, CM | 1 |
| West, A | 1 |
| Sleator, EK | 1 |
| Mitchell, E | 1 |
| Matthews, KL | 1 |
| Bachman, DS | 1 |
| Rapoport, JL | 1 |
| Nee, L | 1 |
| Mitchell, S | 1 |
| Polinsky, R | 1 |
| Ebert, M | 1 |
| Walkup, JT | 1 |
| Scahill, LD | 1 |
| Riddle, MA | 1 |
| Bloomingdale, LM | 1 |
| Dulcan, MK | 1 |
| Erenberg, G | 1 |
| Cruse, RP | 1 |
| Rothner, AD | 1 |
| Golden, GS | 1 |
1 review available for pemoline and Tourette Syndrome
| Article | Year |
|---|---|
Disruptive behavior, hyperactivity, and learning disabilities in children with Tourette's syndrome.
Topics: Adolescent; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Child; | 1995 |
9 other studies available for pemoline and Tourette Syndrome
| Article | Year |
|---|---|
Pemoline induced chorea and Gilles de la Tourette's syndrome.
Topics: Chorea; Humans; Male; Middle Aged; Pemoline; Tourette Syndrome | 1983 |
Deleterious effects of drugs used for hyperactivity on patients with Gilles de la Tourette syndrome.
Topics: Child; Haloperidol; Humans; Hyperkinesis; Male; Methylphenidate; Pemoline; Tourette Syndrome | 1980 |
Gilles de la Tourette's disorder associated with pemoline.
Topics: Attention Deficit Disorder with Hyperactivity; Child; Humans; Male; Pemoline; Tourette Syndrome | 1980 |
Pemoline-induced Tourette's disorder: a case report.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Diseases in Twins; Haloperidol; Humans; M | 1981 |
Hyperkinetic syndrome and Tourette syndrome.
Topics: Adolescent; Child; Dextroamphetamine; Humans; Hyperkinesis; Male; Methylphenidate; Pemoline; Tourett | 1982 |
Change from Mg-pemoline to bupropion in a 12-year-old boy with attention-deficit hyperactivity disorder.
Topics: Antidepressive Agents; Attention; Attention Deficit Disorder with Hyperactivity; Bupropion; Child; D | 1990 |
Attention deficit disorder: evaluation and treatment.
Topics: Age Factors; Anorexia; Attention Deficit Disorder with Hyperactivity; Behavior Therapy; Body Height; | 1985 |
Gilles de la Tourette's syndrome: effects of stimulant drugs.
Topics: Central Nervous System Stimulants; Child; Dextroamphetamine; Humans; Methylphenidate; Pemoline; Tic | 1985 |
The relationship between stimulant medication and tics.
Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Dextroamphe | 1988 |