pemoline has been researched along with Stunted Growth in 5 studies
Pemoline: A central nervous system stimulant used in fatigue and depressive states and to treat hyperkinetic disorders in children.
pemoline : A member of the class of 1,3-oxazoles that is 1,3-oxazol-4(5H)-one which is substituted by an amino group at position 2 and by a phenyl group at position 5. A central nervous system stimulant, it was used to treat hyperactivity disorders in children, but withdrawn from use following reports of serious hepatotoxicity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether treatment of attention deficit hyperactivity disorder (ADHD) with methylphenidate hydrochloride or pemoline diminishes the response to growth hormone (GH) therapy in patients with idiopathic GH deficiency (IGHD) or idiopathic short stature (ISS)." | 1.30 | Response to growth hormone in attention deficit hyperactivity disorder: effects of methylphenidate and pemoline therapy. ( Blethen, SL; Breen, TJ; Julius, JR; Rao, JK, 1998) |
| " The effective dosage of pemoline ranged from 56 to 150 mg/day during the first year of treatment." | 1.26 | Effect on growth in pemoline-treated children with attention deficit disorder. ( Carr, R; Elders, J; Friedmann, N; Ringdahl, I; Roche, A; Thomas, J, 1981) |
| " This temporary effect on growth is present during the first few years of treatment and seems related to drug dosage and to the presence or absence of drug holidays." | 1.26 | The effects of stimulant medication on the growth of hyperkinetic children. ( Hung, W; Lipman, RS; Overall, JE; Roche, AF, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Friedmann, N | 1 |
| Thomas, J | 1 |
| Carr, R | 1 |
| Elders, J | 1 |
| Ringdahl, I | 1 |
| Roche, A | 1 |
| Greenhill, LL | 1 |
| Puig-Antich, J | 1 |
| Halpern, F | 1 |
| Sachar, EJ | 1 |
| Rubinstein, B | 1 |
| Chambers, W | 1 |
| Fiscina, B | 1 |
| Florea, J | 1 |
| Rao, JK | 1 |
| Julius, JR | 1 |
| Breen, TJ | 1 |
| Blethen, SL | 1 |
| Dickinson, LC | 1 |
| Lee, J | 1 |
| Ringdahl, IC | 1 |
| Schedewie, HK | 1 |
| Kilgore, BS | 1 |
| Elders, MJ | 1 |
| Roche, AF | 1 |
| Lipman, RS | 1 |
| Overall, JE | 1 |
| Hung, W | 1 |
5 other studies available for pemoline and Stunted Growth
| Article | Year |
|---|---|
Effect on growth in pemoline-treated children with attention deficit disorder.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Body Height; Body Weight; Child; Female; | 1981 |
Growth disturbances in hyperkinetic children.
Topics: Attention Deficit Disorder with Hyperactivity; Child; Dextroamphetamine; Growth Disorders; Humans; H | 1980 |
Response to growth hormone in attention deficit hyperactivity disorder: effects of methylphenidate and pemoline therapy.
Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Female; Gro | 1998 |
Impaired growth in hyperkinetic children receiving pemoline.
Topics: Body Height; Body Weight; Female; Growth Disorders; Growth Hormone; Humans; Hyperkinesis; Infant; Ma | 1979 |
The effects of stimulant medication on the growth of hyperkinetic children.
Topics: Adolescent; Body Height; Body Weight; Child Behavior Disorders; Dextroamphetamine; Growth; Growth Di | 1979 |