Page last updated: 2024-11-02

pemoline and Sleep Wake Disorders

pemoline has been researched along with Sleep Wake Disorders in 3 studies

Pemoline: A central nervous system stimulant used in fatigue and depressive states and to treat hyperkinetic disorders in children.
pemoline : A member of the class of 1,3-oxazoles that is 1,3-oxazol-4(5H)-one which is substituted by an amino group at position 2 and by a phenyl group at position 5. A central nervous system stimulant, it was used to treat hyperactivity disorders in children, but withdrawn from use following reports of serious hepatotoxicity.

Sleep Wake Disorders: Abnormal sleep-wake schedule or pattern associated with the CIRCADIAN RHYTHM which affect the length, timing, and/or rigidity of the sleep-wake cycle relative to the day-night cycle.

Research Excerpts

ExcerptRelevanceReference
"The authors present five case reports illustrating that 10-20 mg of protriptyline in a single dose at bedtime can effectively control arousal dysfunction (sleep drunkenness and hypersomnia) and the narcolepsycataplexy syndrome without the apparent development of tolerance and without the side effects that are frequent complications of treatment with other agents."7.65Protriptyline: an effective agent in the treatment of the narcolepsy-cataplexy syndrome and hypersomnia. ( Clark, RW; Hyman, PR; Schmidt, HS, 1977)
"The authors present five case reports illustrating that 10-20 mg of protriptyline in a single dose at bedtime can effectively control arousal dysfunction (sleep drunkenness and hypersomnia) and the narcolepsycataplexy syndrome without the apparent development of tolerance and without the side effects that are frequent complications of treatment with other agents."3.65Protriptyline: an effective agent in the treatment of the narcolepsy-cataplexy syndrome and hypersomnia. ( Clark, RW; Hyman, PR; Schmidt, HS, 1977)
"Those disorders discussed are attention deficit disorder, conduct disorders, anxiety disorders, sleep disorders, schizophrenia, autism, Tourette's syndrome, mental retardation, depressive illness, manic depressive illness, eating disorders, and enuresis."2.37Pharmacologic treatment of psychiatric and neurodevelopmental disorders in children and adolescents (Part 1). ( McDaniel, KD, 1986)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schmidt, HS1
Clark, RW1
Hyman, PR1
McDaniel, KD1
Sigwald, J1
Julou, L1
Bouttier, D1
Thomas, J1

Reviews

1 review available for pemoline and Sleep Wake Disorders

ArticleYear
Pharmacologic treatment of psychiatric and neurodevelopmental disorders in children and adolescents (Part 1).
    Clinical pediatrics, 1986, Volume: 25, Issue:2

    Topics: Adolescent; Aggression; Antidepressive Agents; Antipsychotic Agents; Anxiety, Separation; Attention

1986

Other Studies

2 other studies available for pemoline and Sleep Wake Disorders

ArticleYear
Protriptyline: an effective agent in the treatment of the narcolepsy-cataplexy syndrome and hypersomnia.
    The American journal of psychiatry, 1977, Volume: 134, Issue:2

    Topics: Adult; Cataplexy; Dibenzocycloheptenes; Disorders of Excessive Somnolence; Dreams; Drug Therapy, Com

1977
[Therapy of hypersomnia].
    Revue neurologique, 1967, Volume: 116, Issue:6

    Topics: Amphetamine; Animals; Antidepressive Agents; Appetite Depressants; Bemegride; Caffeine; Cats; Centra

1967