pemoline has been researched along with Parkinson Disease in 1 studies
Pemoline: A central nervous system stimulant used in fatigue and depressive states and to treat hyperkinetic disorders in children.
pemoline : A member of the class of 1,3-oxazoles that is 1,3-oxazol-4(5H)-one which is substituted by an amino group at position 2 and by a phenyl group at position 5. A central nervous system stimulant, it was used to treat hyperactivity disorders in children, but withdrawn from use following reports of serious hepatotoxicity.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lewandowski, NM | 1 |
| Ju, S | 1 |
| Verbitsky, M | 1 |
| Ross, B | 1 |
| Geddie, ML | 1 |
| Rockenstein, E | 1 |
| Adame, A | 1 |
| Muhammad, A | 1 |
| Vonsattel, JP | 1 |
| Ringe, D | 1 |
| Cote, L | 1 |
| Lindquist, S | 1 |
| Masliah, E | 1 |
| Petsko, GA | 1 |
| Marder, K | 1 |
| Clark, LN | 1 |
| Small, SA | 1 |
1 other study available for pemoline and Parkinson Disease
| Article | Year |
|---|---|
Polyamine pathway contributes to the pathogenesis of Parkinson disease.
Topics: Acetyltransferases; alpha-Synuclein; Animals; Brain Stem; Diminazene; Genetic Variation; Humans; Mag | 2010 |