Page last updated: 2024-11-02

pemoline and Neoplasms

pemoline has been researched along with Neoplasms in 5 studies

Pemoline: A central nervous system stimulant used in fatigue and depressive states and to treat hyperkinetic disorders in children.
pemoline : A member of the class of 1,3-oxazoles that is 1,3-oxazol-4(5H)-one which is substituted by an amino group at position 2 and by a phenyl group at position 5. A central nervous system stimulant, it was used to treat hyperactivity disorders in children, but withdrawn from use following reports of serious hepatotoxicity.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
" We included studies investigating pemoline and modafinil in participants with multiple sclerosis (MS)-associated fatigue and methylphenidate in patients suffering from advanced cancer and fatigue in meta-analysis."4.91Pharmacological treatments for fatigue associated with palliative care. ( Cuhls, H; Minton, O; Mücke, M; Peuckmann-Post, V; Radbruch, L; Stone, P, 2015)
" Studies investigating amantadine, pemoline, and modafinil in participants with Multiple Sclerosis (MS)-associated fatigue and methylphenidate in patients suffering from advanced cancer and fatigue could be used for meta-analysis."4.86Pharmacological treatments for fatigue associated with palliative care. ( Elsner, F; Krumm, N; Peuckmann, V; Radbruch, L; Trottenberg, P, 2010)
"Further study of MPH use and lymphocytic leukemia risk is needed to determine whether our results are due to chance alone."1.34Methylphenidate use in children and risk of cancer at 18 sites: results of surveillance analyses. ( Chan, J; Friedman, GD; Habel, LA; Jiang, SF; Oestreicher, N; Quesenberry, C, 2007)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mücke, M1
Cuhls, H1
Peuckmann-Post, V1
Minton, O1
Stone, P1
Radbruch, L2
Peuckmann, V1
Elsner, F1
Krumm, N1
Trottenberg, P1
Oestreicher, N1
Friedman, GD1
Jiang, SF1
Chan, J1
Quesenberry, C1
Habel, LA1
Homsi, J1
Walsh, D1
Nelson, KA1
Breitbart, W1
Mermelstein, H1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Feasibility Study of Adjunctive Bright Light Therapy (BLT) for Amelioration of Fatigue in Chinese Cancer Patients Admitted to a Palliative Care Unit[NCT04525924]42 participants (Anticipated)Interventional2020-08-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for pemoline and Neoplasms

ArticleYear
Pharmacological treatments for fatigue associated with palliative care.
    The Cochrane database of systematic reviews, 2015, May-30, Issue:5

    Topics: Adult; Amantadine; Benzhydryl Compounds; Carnitine; Central Nervous System Stimulants; Chronic Disea

2015
Pharmacological treatments for fatigue associated with palliative care.
    The Cochrane database of systematic reviews, 2010, Nov-10, Issue:11

    Topics: Adult; Amantadine; Benzhydryl Compounds; Central Nervous System Stimulants; Fatigue; Humans; Kidney

2010
Psychostimulants in supportive care.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2000, Volume: 8, Issue:5

    Topics: Adult; Caffeine; Central Nervous System Stimulants; Child; Dextroamphetamine; Ephedrine; Humans; Men

2000

Other Studies

2 other studies available for pemoline and Neoplasms

ArticleYear
Methylphenidate use in children and risk of cancer at 18 sites: results of surveillance analyses.
    Pharmacoepidemiology and drug safety, 2007, Volume: 16, Issue:12

    Topics: Adolescent; Age of Onset; Amphetamines; California; Central Nervous System Stimulants; Child; Clinic

2007
Pemoline. An alternative psychostimulant for the management of depressive disorders in cancer patients.
    Psychosomatics, 1992,Summer, Volume: 33, Issue:3

    Topics: Adult; Depressive Disorder; Female; Humans; Male; Middle Aged; Neoplasms; Pemoline; Psychiatric Stat

1992