pemoline has been researched along with Memory Disorders in 4 studies
Pemoline: A central nervous system stimulant used in fatigue and depressive states and to treat hyperkinetic disorders in children.
pemoline : A member of the class of 1,3-oxazoles that is 1,3-oxazol-4(5H)-one which is substituted by an amino group at position 2 and by a phenyl group at position 5. A central nervous system stimulant, it was used to treat hyperactivity disorders in children, but withdrawn from use following reports of serious hepatotoxicity.
Memory Disorders: Disturbances in registering an impression, in the retention of an acquired impression, or in the recall of an impression. Memory impairments are associated with DEMENTIA; CRANIOCEREBRAL TRAUMA; ENCEPHALITIS; ALCOHOLISM (see also ALCOHOL AMNESTIC DISORDER); SCHIZOPHRENIA; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To review the numerous reports of hepatotoxic adverse drug reactions (ADRs) ascribed to pemoline that were sent to the U." | 1.31 | Pemoline hepatotoxicity and postmarketing surveillance. ( Gardner, JE; Safer, DJ; Zito, JM, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Safer, DJ | 1 |
| Zito, JM | 1 |
| Gardner, JE | 1 |
| Tolman, KG | 1 |
| Freston, JW | 1 |
| Berenson, MM | 1 |
| Sannella, JJ | 1 |
| Droller, H | 1 |
| Bevans, HG | 1 |
| Jayaram, VK | 1 |
| Plotnikoff, N | 1 |
1 trial available for pemoline and Memory Disorders
| Article | Year |
|---|---|
Problems of a drug trial (Pemoline) on geriatric patients.
Topics: Aged; Clinical Trials as Topic; Electroencephalography; Female; Humans; Memory; Memory Disorders; Pe | 1971 |
3 other studies available for pemoline and Memory Disorders
| Article | Year |
|---|---|
Pemoline hepatotoxicity and postmarketing surveillance.
Topics: Adolescent; Aged; Aged, 80 and over; Central Nervous System Stimulants; Chemical and Drug Induced Li | 2001 |
Hepatotoxicity due to pemoline. Report of two cases.
Topics: Aged; Alkaline Phosphatase; Aspartate Aminotransferases; Biopsy; Chemical and Drug Induced Liver Inj | 1973 |
Comparison of PMH (1) and pemoline activity after electroconvulsive shock.
Topics: Animals; Avoidance Learning; Central Nervous System; Conditioning, Psychological; Drug Synergism; El | 1970 |