pemoline has been researched along with Liver Diseases in 3 studies
Pemoline: A central nervous system stimulant used in fatigue and depressive states and to treat hyperkinetic disorders in children.
pemoline : A member of the class of 1,3-oxazoles that is 1,3-oxazol-4(5H)-one which is substituted by an amino group at position 2 and by a phenyl group at position 5. A central nervous system stimulant, it was used to treat hyperactivity disorders in children, but withdrawn from use following reports of serious hepatotoxicity.
Liver Diseases: Pathological processes of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To review the numerous reports of hepatotoxic adverse drug reactions (ADRs) ascribed to pemoline that were sent to the U." | 1.31 | Pemoline hepatotoxicity and postmarketing surveillance. ( Gardner, JE; Safer, DJ; Zito, JM, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Safer, DJ | 1 |
| Zito, JM | 1 |
| Gardner, JE | 1 |
| Nehra, A | 1 |
| Mullick, F | 1 |
| Ishak, KG | 1 |
| Zimmerman, HJ | 1 |
| Elitsur, Y | 1 |
3 other studies available for pemoline and Liver Diseases
| Article | Year |
|---|---|
Pemoline hepatotoxicity and postmarketing surveillance.
Topics: Adolescent; Aged; Aged, 80 and over; Central Nervous System Stimulants; Chemical and Drug Induced Li | 2001 |
Pemoline-associated hepatic injury.
Topics: Adolescent; Adult; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Humans; Liver Di | 1990 |
Pemoline (Cylert)-induced hepatotoxicity.
Topics: Attention Deficit Disorder with Hyperactivity; Chemical and Drug Induced Liver Injury; Child; Female | 1990 |