pemoline has been researched along with Hyperactivity, Motor in 29 studies
Pemoline: A central nervous system stimulant used in fatigue and depressive states and to treat hyperkinetic disorders in children.
pemoline : A member of the class of 1,3-oxazoles that is 1,3-oxazol-4(5H)-one which is substituted by an amino group at position 2 and by a phenyl group at position 5. A central nervous system stimulant, it was used to treat hyperactivity disorders in children, but withdrawn from use following reports of serious hepatotoxicity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gilles de la Tourette syndrome is frequently associated with symptoms characteristic of hyperactivity and often goes unrecognized for long periods of time." | 1.26 | Deleterious effects of drugs used for hyperactivity on patients with Gilles de la Tourette syndrome. ( Sleator, EK, 1980) |
| " The combination of a clinically useful medication in appropriate dosage schedules with relevant psychological treatments simultaneously directed to each of the child's many disabilities were associated with an unexpectedly good outcome at the end of one and two years." | 1.26 | Multimodality treatment. A two-year evaluation of 61 hyperactive boys. ( Cantwell, DP; Satterfield, BT; Satterfield, JH, 1980) |
| " This temporary effect on growth is present during the first few years of treatment and seems related to drug dosage and to the presence or absence of drug holidays." | 1.26 | The effects of stimulant medication on the growth of hyperkinetic children. ( Hung, W; Lipman, RS; Overall, JE; Roche, AF, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (96.55) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (3.45) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Martin, CA | 1 |
| Welsh, RJ | 1 |
| McKay, SE | 1 |
| Bareuther, CM | 1 |
| Sleator, EK | 1 |
| Rapoport, JL | 1 |
| Nee, L | 1 |
| Mitchell, S | 1 |
| Polinsky, R | 1 |
| Ebert, M | 1 |
| Dickerson, JW | 1 |
| Pepler, F | 1 |
| Tomkins, CP | 1 |
| Soldin, SJ | 1 |
| MacLeod, SM | 1 |
| Rochefort, JG | 1 |
| Swanson, JM | 1 |
| Greenhill, LL | 1 |
| Puig-Antich, J | 1 |
| Halpern, F | 1 |
| Sachar, EJ | 1 |
| Rubinstein, B | 1 |
| Chambers, W | 1 |
| Fiscina, B | 1 |
| Florea, J | 1 |
| Satterfield, JH | 1 |
| Satterfield, BT | 1 |
| Cantwell, DP | 1 |
| Nakamura, H | 1 |
| Blumer, JL | 1 |
| Reed, MD | 1 |
| Hastings, JE | 1 |
| Barkley, RA | 2 |
| Barker, D | 1 |
| Krager, JM | 1 |
| Safer, D | 1 |
| Earhart, J | 1 |
| Wolraich, ML | 1 |
| Margolin, DI | 1 |
| Dickinson, LC | 1 |
| Lee, J | 1 |
| Ringdahl, IC | 1 |
| Schedewie, HK | 1 |
| Kilgore, BS | 1 |
| Elders, MJ | 1 |
| Roche, AF | 1 |
| Lipman, RS | 1 |
| Overall, JE | 1 |
| Hung, W | 1 |
| Small, JG | 1 |
| Milstein, V | 1 |
| Jay, S | 1 |
| Seals, JR | 1 |
| White, JH | 1 |
| Everett, GM | 1 |
| Halpern, WI | 1 |
| Millichap, JG | 1 |
| Cerný, L | 1 |
| Kucerová, Z | 1 |
| Sturma, J | 1 |
| Plotnikoff, N | 1 |
| Conners, CK | 1 |
| Taylor, E | 1 |
| Meo, G | 1 |
| Kurtz, MA | 1 |
| Fournier, M | 1 |
| Peters, JE | 1 |
| Spencer, DA | 1 |
| Triantafillou, M | 1 |
7 reviews available for pemoline and Hyperactivity, Motor
| Article | Year |
|---|---|
Hyperactivity (attention-deficit disorder).
Topics: Attention Deficit Disorder with Hyperactivity; Child; Dextroamphetamine; Family; Female; Humans; Hyp | 1984 |
Diet and hyperactivity.
Topics: Adolescent; Aging; Amphetamines; Child; Child Behavior Disorders; Child, Preschool; Diet; Dietary Ca | 1980 |
Pemoline ingestion in children: a report of five cases and review of the literature.
Topics: Adolescent; Benzodiazepines; Central Nervous System Stimulants; Charcoal; Child, Preschool; Drug Ove | 2002 |
A review of stimulant drug research with hyperactive children.
Topics: Achievement; Amphetamines; Attention; Autonomic Nervous System; Body Height; Body Weight; Cerebral C | 1977 |
The hyperkinetic child syndrome and brain monoamines: pharmacology and therapeutic implications.
Topics: Animals; Arousal; Attention; Brain; Child; Dextroamphetamine; Disease Models, Animal; Dopamine; Huma | 1978 |
MBD: advanced in understanding many bothersome dilemmas.
Topics: Adolescent; Adult; Attention; Attention Deficit Disorder with Hyperactivity; Child; Child, Preschool | 1976 |
Pemoline: review of performance.
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Behavior; Brain Diseases; Conditioning, Psyc | 1971 |
3 trials available for pemoline and Hyperactivity, Motor
| Article | Year |
|---|---|
Stimulant drug therapy in hyperactive children: research and clinical implications.
Topics: Adolescent; Behavior Therapy; Child; Child, Preschool; Clinical Trials as Topic; Dextroamphetamine; | 1977 |
Magnesium pemoline and dextroamphetamine: a controlled study in children with minimal brain dysfunction.
Topics: Analysis of Variance; Anxiety; Attention; Attention Deficit Disorder with Hyperactivity; Child; Dext | 1972 |
Ronyl (pemoline) in overactive mentally subnormal children.
Topics: Adolescent; Child; Clinical Trials as Topic; Female; Humans; Hyperkinesis; Intellectual Disability; | 1970 |
19 other studies available for pemoline and Hyperactivity, Motor
| Article | Year |
|---|---|
Deleterious effects of drugs used for hyperactivity on patients with Gilles de la Tourette syndrome.
Topics: Child; Haloperidol; Humans; Hyperkinesis; Male; Methylphenidate; Pemoline; Tourette Syndrome | 1980 |
Hyperkinetic syndrome and Tourette syndrome.
Topics: Adolescent; Child; Dextroamphetamine; Humans; Hyperkinesis; Male; Methylphenidate; Pemoline; Tourett | 1982 |
Analysis of pemoline in serum by high performance liquid chromatography: clinical application to optimize treatment of hyperactive children.
Topics: Adolescent; Child; Child, Preschool; Chromatography, High Pressure Liquid; Dose-Response Relationshi | 1980 |
Growth disturbances in hyperkinetic children.
Topics: Attention Deficit Disorder with Hyperactivity; Child; Dextroamphetamine; Growth Disorders; Humans; H | 1980 |
Multimodality treatment. A two-year evaluation of 61 hyperactive boys.
Topics: Achievement; Attention; Child; Dextroamphetamine; Humans; Hyperkinesis; Male; Methylphenidate; Motor | 1980 |
A review of psychophysiological research with hyperkinetic children.
Topics: Amphetamines; Attention Deficit Disorder with Hyperactivity; Autonomic Nervous System; Blood Pressur | 1978 |
Hyperkinesia and its treatment.
Topics: Amphetamines; Humans; Hyperkinesis; Methylphenidate; Pemoline | 1978 |
Follow-up survey results of medication used to treat hyperactive school children.
Topics: Child; Dextroamphetamine; Drug Prescriptions; Follow-Up Studies; Humans; Hyperkinesis; Income; Maryl | 1979 |
Impaired growth in hyperkinetic children receiving pemoline.
Topics: Body Height; Body Weight; Female; Growth Disorders; Growth Hormone; Humans; Hyperkinesis; Infant; Ma | 1979 |
The effects of stimulant medication on the growth of hyperkinetic children.
Topics: Adolescent; Body Height; Body Weight; Child Behavior Disorders; Dextroamphetamine; Growth; Growth Di | 1979 |
Clinical EEG studies of short and long term stimulant drug therapy of hyperkinetic children.
Topics: Child; Electroencephalography; Humans; Hyperkinesis; Pemoline; Time Factors | 1978 |
The hyperactive child syndrome.
Topics: Child; Dextroamphetamine; Diphenhydramine; Humans; Hyperkinesis; Imipramine; Methylphenidate; Pemoli | 1977 |
Methylphenidate (ritalin) and other drugs for treatment of hyperactive children.
Topics: Child; Deanol; Dextroamphetamine; Drug Interactions; Humans; Hyperkinesis; Imipramine; Methylphenida | 1977 |
Dopamine and the hyperkinetic child.
Topics: Biogenic Amines; Child; Dopamine; Electroencephalography; Humans; Hyperkinesis; Pemoline; Sympathomi | 1977 |
The medication clinic in the spectrum of children's services.
Topics: Child; Child Health Services; Child, Preschool; Dextroamphetamine; Female; Humans; Hyperkinesis; Mal | 1977 |
The hyperactive child.
Topics: Achievement; Age Factors; Attention Deficit Disorder with Hyperactivity; Child; Child, Preschool; Cr | 1976 |
Proceedings: Pemoline in comparison with amphetamine and placebo in pedo-psychiatric practice.
Topics: Adolescent; Amphetamine; Child; Female; Humans; Hyperkinesis; Male; Pemoline | 1975 |
Minimal brain dysfunctions in children.
Topics: Amphetamine; Attention; Attention Deficit Disorder with Hyperactivity; Child; Child, Preschool; Comm | 1974 |
Pemoline in overactive mentally handicapped children.
Topics: Adolescent; Child; Humans; Hyperkinesis; Intellectual Disability; Pemoline | 1972 |