Page last updated: 2024-11-02

pemoline and Hepatic Failure

pemoline has been researched along with Hepatic Failure in 3 studies

Pemoline: A central nervous system stimulant used in fatigue and depressive states and to treat hyperkinetic disorders in children.
pemoline : A member of the class of 1,3-oxazoles that is 1,3-oxazol-4(5H)-one which is substituted by an amino group at position 2 and by a phenyl group at position 5. A central nervous system stimulant, it was used to treat hyperactivity disorders in children, but withdrawn from use following reports of serious hepatotoxicity.

Research Excerpts

ExcerptRelevanceReference
"Pemoline is a central nervous system (CNS) stimulant approved for use as part of the comprehensive medical management of attention deficit hyperactivity disorder (ADHD)."6.40Pemoline-associated hepatic failure: a critical analysis of the literature. ( Schreiber, R; Shevell, M, 1997)
"Pemoline is a central nervous system (CNS) stimulant approved for use as part of the comprehensive medical management of attention deficit hyperactivity disorder (ADHD)."2.40Pemoline-associated hepatic failure: a critical analysis of the literature. ( Schreiber, R; Shevell, M, 1997)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shader, RI1
Shevell, M1
Schreiber, R1
Hogan, V1

Reviews

1 review available for pemoline and Hepatic Failure

ArticleYear
Pemoline-associated hepatic failure: a critical analysis of the literature.
    Pediatric neurology, 1997, Volume: 16, Issue:1

    Topics: Adverse Drug Reaction Reporting Systems; Attention Deficit Disorder with Hyperactivity; Central Nerv

1997

Other Studies

2 other studies available for pemoline and Hepatic Failure

ArticleYear
Drug-attributed hepatic failure: causality, risk assessment, consent, and confusion.
    Journal of clinical psychopharmacology, 2003, Volume: 23, Issue:6

    Topics: Central Nervous System Stimulants; Confusion; Humans; Informed Consent; Liver Failure; Patients; Pem

2003
Pemoline (Cylert): market withdrawal.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2000, Jan-11, Volume: 162, Issue:1

    Topics: Adverse Drug Reaction Reporting Systems; Attention Deficit Disorder with Hyperactivity; Canada; Cent

2000