pemoline has been researched along with Dyskinesia Syndromes in 5 studies
Pemoline: A central nervous system stimulant used in fatigue and depressive states and to treat hyperkinetic disorders in children.
pemoline : A member of the class of 1,3-oxazoles that is 1,3-oxazol-4(5H)-one which is substituted by an amino group at position 2 and by a phenyl group at position 5. A central nervous system stimulant, it was used to treat hyperactivity disorders in children, but withdrawn from use following reports of serious hepatotoxicity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report two case histories of previously healthy patients who both developed persistent dyskinetic syndromes (spasmodic torticollis and cranial dystonia, respectively) following the intake of norpseudoephedrine (NPE) as an appetite suppressant." | 3.69 | Dyskinesias possibly induced by norpseudoephedrine. ( Dressler, D; Thiel, A, 1994) |
| " While there have been a few reports of tolerance, it is possible that these were a reflection of inadequate dosing rather than actual tolerance to the drug's therapeutic effects." | 1.27 | Evidence of lack of abuse or dependence following pemoline treatment: results of a retrospective survey. ( Bartenbach, DE; Davis, PM; Langer, DH; Menander, KB; Sweeney, KP, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kasim, S | 1 |
| Jinnah, HA | 1 |
| Thiel, A | 1 |
| Dressler, D | 1 |
| Shuster, J | 1 |
| Sallee, FR | 1 |
| Stiller, RL | 1 |
| Perel, JM | 1 |
| Everett, G | 1 |
| Langer, DH | 1 |
| Sweeney, KP | 1 |
| Bartenbach, DE | 1 |
| Davis, PM | 1 |
| Menander, KB | 1 |
5 other studies available for pemoline and Dyskinesia Syndromes
| Article | Year |
|---|---|
Pharmacologic thresholds for self-injurious behavior in a genetic mouse model of Lesch-Nyhan disease.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2002 |
Dyskinesias possibly induced by norpseudoephedrine.
Topics: Adult; Amphetamine; Appetite Depressants; Brain; Female; Humans; Magnetic Resonance Imaging; Methylp | 1994 |
Adverse drug reaction. Pemoline and dyskinesia.
Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Humans; Mal | 1999 |
Pemoline-induced abnormal involuntary movements.
Topics: Attention Deficit Disorder with Hyperactivity; Child; Humans; Male; Movement Disorders; Pemoline | 1989 |
Evidence of lack of abuse or dependence following pemoline treatment: results of a retrospective survey.
Topics: Adolescent; Adult; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorders; C | 1986 |