pemoline has been researched along with Disease Models, Animal in 17 studies
Pemoline: A central nervous system stimulant used in fatigue and depressive states and to treat hyperkinetic disorders in children.
pemoline : A member of the class of 1,3-oxazoles that is 1,3-oxazol-4(5H)-one which is substituted by an amino group at position 2 and by a phenyl group at position 5. A central nervous system stimulant, it was used to treat hyperactivity disorders in children, but withdrawn from use following reports of serious hepatotoxicity.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.76) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 8 (47.06) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Muehlmann, AM | 6 |
| Wolfman, SL | 1 |
| Devine, DP | 11 |
| Yuan, X | 1 |
| Wilkinson, JA | 1 |
| Kies, SD | 2 |
| Turner, CA | 1 |
| Wolfman, S | 1 |
| Lewis, MH | 1 |
| Bloom, CM | 1 |
| Holly, S | 1 |
| Miller, AM | 1 |
| Blake, BL | 1 |
| Egami, K | 1 |
| Breese, GR | 1 |
| Jinnah, HA | 1 |
| Brown, BD | 1 |
| King, BH | 2 |
| Cromwell, HC | 2 |
| Lee, HT | 1 |
| Behrstock, SP | 1 |
| Schmanke, T | 1 |
| Maidment, NT | 1 |
| Levine, MS | 1 |
| Margolin, DI | 1 |
| Fog, R | 1 |
3 reviews available for pemoline and Disease Models, Animal
| Article | Year |
|---|---|
Dopaminergic and glutamatergic interactions in the expression of self-injurious behavior.
Topics: Animals; Central Nervous System Stimulants; Cerebral Cortex; Corpus Striatum; Disease Models, Animal | 1998 |
The hyperkinetic child syndrome and brain monoamines: pharmacology and therapeutic implications.
Topics: Animals; Arousal; Attention; Brain; Child; Dextroamphetamine; Disease Models, Animal; Dopamine; Huma | 1978 |
On stereotypy and catalepsy: studies on the effect of amphetamines and neuroleptics in rats.
Topics: Amphetamine; Animals; Basal Ganglia; Caffeine; Catalepsy; Cocaine; Compulsive Behavior; Corpus Stria | 1972 |
14 other studies available for pemoline and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
The role of neurotensin in vulnerability for self-injurious behaviour: studies in a rodent model.
Topics: Animals; Behavior, Animal; Blotting, Western; Brain; Disease Models, Animal; Male; Neurotensin; Pemo | 2018 |
The Pemoline Model of Self-Injurious Behavior: An Update.
Topics: Animals; Central Nervous System Stimulants; Disease Models, Animal; Female; Humans; Male; Mental Dis | 2019 |
The role of anxiety in vulnerability for self-injurious behaviour: studies in a rodent model.
Topics: Analysis of Variance; Animals; Anxiety; Carbolines; Disease Models, Animal; Disease Susceptibility; | 2016 |
Individual differences in vulnerability for self-injurious behavior: studies using an animal model.
Topics: Animals; Central Nervous System Stimulants; Disease Models, Animal; Individuality; Male; Motor Activ | 2011 |
Self-injurious behaviour: limbic dysregulation and stress effects in an animal model.
Topics: Animals; Central Nervous System Stimulants; Corpus Striatum; Disease Models, Animal; Electron Transp | 2012 |
Animal models of self-injurious behaviour: an overview.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2012 |
The pemoline model of self-injurious behaviour.
Topics: Animals; Disease Models, Animal; Dopamine; Humans; Mice; Mood Disorders; Pemoline; Personality Disor | 2012 |
Self-injurious behavior vs. nonsuicidal self-injury: the CNS stimulant pemoline as a model of self-destructive behavior.
Topics: Animals; Central Nervous System Stimulants; Disease Models, Animal; Female; Humans; Pemoline; Rats; | 2012 |
Self-injurious behaviour: a comparison of caffeine and pemoline models in rats.
Topics: Adrenocorticotropic Hormone; Animals; Caffeine; Corticosterone; Disease Models, Animal; Dose-Respons | 2004 |
Nifedipine suppresses self-injurious behaviors in animals.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2007 |
Pemoline (2-amino-5-phenyl-1,3-oxazol-4-one)-induced self-injurious behavior: a rodent model of pharmacotherapeutic efficacy.
Topics: Animals; Antipsychotic Agents; Central Nervous System Stimulants; Disease Models, Animal; Fructose; | 2008 |
Glutamate-mediated neuroplasticity in an animal model of self-injurious behaviour.
Topics: Animals; Behavior, Animal; Biogenic Monoamines; Disease Models, Animal; Dizocilpine Maleate; Excitat | 2008 |
Cortical damage enhances pemoline-induced self-injurious behavior in prepubertal rats.
Topics: Animals; Brain Injuries; Disease Models, Animal; Humans; Male; Pemoline; Rats; Self-Injurious Behavi | 1999 |