pemoline has been researched along with Depressive Disorder in 10 studies
Pemoline: A central nervous system stimulant used in fatigue and depressive states and to treat hyperkinetic disorders in children.
pemoline : A member of the class of 1,3-oxazoles that is 1,3-oxazol-4(5H)-one which is substituted by an amino group at position 2 and by a phenyl group at position 5. A central nervous system stimulant, it was used to treat hyperactivity disorders in children, but withdrawn from use following reports of serious hepatotoxicity.
Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pemoline was associated with a significant decrease in the high frequency (HF) power (0." | 2.71 | Effect of fluoxetine, pemoline and placebo on heart period and QT variability in normal humans. ( Balon, R; Doll, RG; Jayaraman, A; Pohl, R; Yeragani, V, 2003) |
| "Pemoline was given orally in increasing doses ranging from 20 to 80 mg/day." | 1.27 | EEG and clinical findings during pemoline treatment in children and adults with attention deficit disorder. An 8-week open trial. ( Barteselli, F; Besana, R; Caresia, L; Guareschi Cazzullo, A; Musetti, L; Pugnetti, L; Scarone, S, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 7 (70.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pohl, R | 1 |
| Balon, R | 1 |
| Jayaraman, A | 1 |
| Doll, RG | 1 |
| Yeragani, V | 1 |
| Caresia, L | 1 |
| Pugnetti, L | 1 |
| Besana, R | 1 |
| Barteselli, F | 1 |
| Guareschi Cazzullo, A | 1 |
| Musetti, L | 1 |
| Scarone, S | 1 |
| Holmes, VF | 1 |
| Benazzi, F | 1 |
| Nierenberg, AA | 1 |
| Dougherty, D | 1 |
| Rosenbaum, JF | 1 |
| Breitbart, W | 1 |
| Mermelstein, H | 1 |
| Metz, A | 1 |
| Shader, RI | 1 |
| Fawcett, J | 1 |
| Kravitz, HM | 1 |
| Zajecka, JM | 1 |
| Schaff, MR | 1 |
| Warneke, L | 1 |
| Chiarello, RJ | 1 |
| Cole, JO | 1 |
4 reviews available for pemoline and Depressive Disorder
| Article | Year |
|---|---|
Medical use of psychostimulants: an overview.
Topics: Central Nervous System Stimulants; Depressive Disorder; Dextroamphetamine; Drug Interactions; Humans | 1995 |
Dopaminergic agents and stimulants as antidepressant augmentation strategies.
Topics: Antidepressive Agents; Central Nervous System Stimulants; Depressive Disorder; Dopamine Agents; Drug | 1998 |
Psychostimulants in psychiatry.
Topics: Adult; Depressive Disorder; Dextroamphetamine; Female; Humans; Male; Mental Disorders; Methylphenida | 1990 |
The use of psychostimulants in general psychiatry. A reconsideration.
Topics: Adult; Amphetamine; Central Nervous System Stimulants; Clinical Trials as Topic; Depressive Disorder | 1987 |
2 trials available for pemoline and Depressive Disorder
| Article | Year |
|---|---|
Effect of fluoxetine, pemoline and placebo on heart period and QT variability in normal humans.
Topics: Adult; Anxiety Disorders; Cardiac Output; Central Nervous System Stimulants; Death, Sudden, Cardiac; | 2003 |
The use of psychostimulants in general psychiatry. A reconsideration.
Topics: Adult; Amphetamine; Central Nervous System Stimulants; Clinical Trials as Topic; Depressive Disorder | 1987 |
5 other studies available for pemoline and Depressive Disorder
| Article | Year |
|---|---|
EEG and clinical findings during pemoline treatment in children and adults with attention deficit disorder. An 8-week open trial.
Topics: Adolescent; Adult; Anxiety Disorders; Attention Deficit Disorder with Hyperactivity; Child; Depressi | 1984 |
Pemoline augmentation for resistant depression.
Topics: Central Nervous System Stimulants; Depressive Disorder; Dopamine; Dose-Response Relationship, Drug; | 1997 |
Pemoline. An alternative psychostimulant for the management of depressive disorders in cancer patients.
Topics: Adult; Depressive Disorder; Female; Humans; Male; Middle Aged; Neoplasms; Pemoline; Psychiatric Stat | 1992 |
Combination of fluoxetine with pemoline in the treatment of major depressive disorder.
Topics: Adult; Depressive Disorder; Drug Therapy, Combination; Female; Fluoxetine; Humans; Middle Aged; Pemo | 1991 |
CNS stimulant potentiation of monoamine oxidase inhibitors in treatment-refractory depression.
Topics: Bipolar Disorder; Depressive Disorder; Dextroamphetamine; Dose-Response Relationship, Drug; Drug Syn | 1991 |