Page last updated: 2024-11-02

pemoline and De Lange Syndrome

pemoline has been researched along with De Lange Syndrome in 1 studies

Pemoline: A central nervous system stimulant used in fatigue and depressive states and to treat hyperkinetic disorders in children.
pemoline : A member of the class of 1,3-oxazoles that is 1,3-oxazol-4(5H)-one which is substituted by an amino group at position 2 and by a phenyl group at position 5. A central nervous system stimulant, it was used to treat hyperactivity disorders in children, but withdrawn from use following reports of serious hepatotoxicity.

De Lange Syndrome: A syndrome characterized by growth retardation, severe MENTAL RETARDATION, short stature, a low-pitched growling cry, brachycephaly, low-set ears, webbed neck, carp mouth, depressed nasal bridge, bushy eyebrows meeting at the midline, hirsutism, and malformations of the hands. The condition may occur sporadically or be associated with an autosomal dominant pattern of inheritance or duplication of the long arm of chromosome 3. (Menkes, Textbook of Child Neurology, 5th ed, p231)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mueller, K1
Hsiao, S1

Other Studies

1 other study available for pemoline and De Lange Syndrome

ArticleYear
Pemoline-induced self-biting in rats and self-mutilation in the deLange syndrome.
    Pharmacology, biochemistry, and behavior, 1980, Volume: 13, Issue:5

    Topics: Animals; De Lange Syndrome; Humans; Male; Pemoline; Rats; Self Mutilation; Social Behavior; Stereoty

1980