Page last updated: 2024-11-02

pemoline and Conduct Disorder

pemoline has been researched along with Conduct Disorder in 1 studies

Pemoline: A central nervous system stimulant used in fatigue and depressive states and to treat hyperkinetic disorders in children.
pemoline : A member of the class of 1,3-oxazoles that is 1,3-oxazol-4(5H)-one which is substituted by an amino group at position 2 and by a phenyl group at position 5. A central nervous system stimulant, it was used to treat hyperactivity disorders in children, but withdrawn from use following reports of serious hepatotoxicity.

Conduct Disorder: A repetitive and persistent pattern of behavior in which the basic rights of others or major age-appropriate societal norms or rules are violated. These behaviors include aggressive conduct that causes or threatens physical harm to other people or animals, nonaggressive conduct that causes property loss or damage, deceitfulness or theft, and serious violations of rules. The onset is before age 18. (From DSM-IV, 1994)

Research Excerpts

ExcerptRelevanceReference
"Sixty-nine adolescents (aged 13-19) with conduct disorder (CD), SUD, and ADHD were recruited from the community and randomly assigned to a 12-week clinical trial of pemoline (n = 35) or placebo (n = 34), titrated over 4 weeks to a single morning dose of 75 to 112."5.11A randomized controlled trial of pemoline for attention-deficit/hyperactivity disorder in substance-abusing adolescents. ( Hall, SK; Kayser, A; Lohman, M; Mikulich-Gilbertson, SK; Riggs, PD, 2004)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Riggs, PD1
Hall, SK1
Mikulich-Gilbertson, SK1
Lohman, M1
Kayser, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Substance Dependent Teens - Impact of Treating Depression Study 1[NCT00061113]Phase 4126 participants (Actual)Interventional2001-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for pemoline and Conduct Disorder

ArticleYear
A randomized controlled trial of pemoline for attention-deficit/hyperactivity disorder in substance-abusing adolescents.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2004, Volume: 43, Issue:4

    Topics: Adolescent; Adult; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants;

2004