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pemoline and Chemical and Drug Induced Liver Injury, Chronic

pemoline has been researched along with Chemical and Drug Induced Liver Injury, Chronic in 1 studies

Pemoline: A central nervous system stimulant used in fatigue and depressive states and to treat hyperkinetic disorders in children.
pemoline : A member of the class of 1,3-oxazoles that is 1,3-oxazol-4(5H)-one which is substituted by an amino group at position 2 and by a phenyl group at position 5. A central nervous system stimulant, it was used to treat hyperactivity disorders in children, but withdrawn from use following reports of serious hepatotoxicity.

Chemical and Drug Induced Liver Injury, Chronic: Liver disease lasting six months or more, caused by an adverse effect of a drug or chemical. The adverse effect may be caused by drugs, drug metabolites, chemicals from the environment, or an idiosyncratic response.

Research Excerpts

ExcerptRelevanceReference
"Pemoline therapy was discontinued, but the patient's liver function continued to decline."1.30Pemoline therapy resulting in liver transplantation. ( Adcock, KG; Farrington, EA; MacElroy, DE; Wolford, ET, 1998)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adcock, KG1
MacElroy, DE1
Wolford, ET1
Farrington, EA1

Other Studies

1 other study available for pemoline and Chemical and Drug Induced Liver Injury, Chronic

ArticleYear
Pemoline therapy resulting in liver transplantation.
    The Annals of pharmacotherapy, 1998, Volume: 32, Issue:4

    Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Chemical and Drug

1998