Page last updated: 2024-11-02

pemoline and Amnesia

pemoline has been researched along with Amnesia in 2 studies

Pemoline: A central nervous system stimulant used in fatigue and depressive states and to treat hyperkinetic disorders in children.
pemoline : A member of the class of 1,3-oxazoles that is 1,3-oxazol-4(5H)-one which is substituted by an amino group at position 2 and by a phenyl group at position 5. A central nervous system stimulant, it was used to treat hyperactivity disorders in children, but withdrawn from use following reports of serious hepatotoxicity.

Amnesia: Pathologic partial or complete loss of the ability to recall past experiences (AMNESIA, RETROGRADE) or to form new memories (AMNESIA, ANTEROGRADE). This condition may be of organic or psychologic origin. Organic forms of amnesia are usually associated with dysfunction of the DIENCEPHALON or HIPPOCAMPUS. (From Adams et al., Principles of Neurology, 6th ed, pp426-7)

Research Excerpts

ExcerptRelevanceReference
" Active compounds exhibited an inverted U-shaped dose-response curve."5.27Amnesia-reversal activity of a series of N-[(disubstituted-amino)alkyl] -2-oxo-1-pyrrolidineacetamides, including pramiracetam. ( Butler, DE; L'Italien, YJ; Marriott, JG; Nordin, IC; Poschel, PH; Zweisler, L, 1984)
" Active compounds exhibited an inverted U-shaped dose-response curve."1.27Amnesia-reversal activity of a series of N-[(disubstituted-amino)alkyl] -2-oxo-1-pyrrolidineacetamides, including pramiracetam. ( Butler, DE; L'Italien, YJ; Marriott, JG; Nordin, IC; Poschel, PH; Zweisler, L, 1984)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Butler, DE1
Nordin, IC1
L'Italien, YJ1
Zweisler, L1
Poschel, PH1
Marriott, JG1
Stein, DG1
Brink, JJ1

Other Studies

2 other studies available for pemoline and Amnesia

ArticleYear
Amnesia-reversal activity of a series of N-[(disubstituted-amino)alkyl] -2-oxo-1-pyrrolidineacetamides, including pramiracetam.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:5

    Topics: Amnesia; Animals; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electroshock; Huma

1984
Prevention of retrograde amnesia by injection of magnesium pemoline in dimethylsulfoxide.
    Psychopharmacologia, 1969, Volume: 14, Issue:3

    Topics: Amnesia; Animals; Avoidance Learning; Dimethyl Sulfoxide; Electric Stimulation; Electroshock; Humans

1969