pectins and Hyperlipoproteinemias

Water-soluble dietary fibres are widely used in preventive and curative nutrition, especially in cases of hyperlipoproteinemia. Occurrence of disturbances of the electrolyte and trace element metabolism causing adverse effects in long-term treatment with pectin can be theoretically substantiated.. Seventy three patients with hyperlipoproteinemia, aged from 40 to 69 years, were included in the study. They were treated with a natural product, based on high-esterified pectin granulated with sorbitol. The patients were examined prior to the treatment and once monthly during the three-month course of therapy.. The results of the comparative assessment of the electrolytes (sodium, potassium, chloride, ionised calcium, total and ionised magnesium) failed to reach statistical significance during the administration of the pectin product. Neither did the serum level of trace elements (iron and copper) change significantly during the observed period.. The biochemical analysis of the serum level of certain electrolytes and trace elements indicate that daily administration of 15 g of high-esterified apple pectin for a three-month period has no adverse effects. Therefore pectin products can be included in the therapeutic schedule in the treatment of hyperlipoproteinemia.

Topics: Adult; Aged; Electrolytes; Female; Humans; Hyperlipoproteinemias; Male; Middle Aged; Pectins; Trace Elements

Seventy one patients with nutritional-metabolic obesity (II--IV degree) were examined, with or without hyperlipoproteinemia, treated in hospitals or sanatoria for 25 days. The effect of the hypoenergy diet regimen (5,94 kJ = 1460 cal) was studied, that was combined with an average daily import of 11 g esterified, apple pectin (in fruit pastes and drinks) upon the level of 6 serum lipid indices. A decrease (less than 0,05) of total cholesterol, triglycerides and some other lipid indices was established both in the patients with hyperlipoproteinemia type II (IIa and IIb) and type IV, in those without hyperlipoproteinemia syndrome as well. Due to the hypolipidemic effect established the newly produced articles with high esterified apple pectin are recommended in the complex treatment of the patients with obesity (with or without secondary hyperlipoproteinemeia.

Topics: Adult; Female; Humans; Hyperlipoproteinemias; Lipids; Male; Middle Aged; Obesity; Pectins

Topics: Adult; Animals; Energy Intake; Evaluation Studies as Topic; Glycine max; Humans; Hyperlipoproteinemias; Lipids; Middle Aged; Milk; Pectins

Topics: Animals; Bile Acids and Salts; Binding Sites; Carrageenan; Cellulose; Dietary Fiber; Humans; Hyperlipoproteinemias; Pectins; Rats