pectins and Hemorrhage

pectins has been researched along with Hemorrhage* in 7 studies

Reviews

1 review(s) available for pectins and Hemorrhage

ArticleYear
[ANTIPLASMIN DRUGS].
    [Sogo rinsho] Clinic all-round, 1963, Volume: 12

    Topics: alpha-2-Antiplasmin; Aminocaproates; Aminocaproic Acid; Antifibrinolytic Agents; Asthma; Blood Platelets; Cholesterol; Fibrinolysis; Hemophilia A; Hemorrhage; Kidney Diseases; Liver Cirrhosis; Pectins; Pharmacology; Serotonin; Trypsin

1963

Other Studies

6 other study(ies) available for pectins and Hemorrhage

ArticleYear
Physico chemical characterisation of pectin incorporated gelatin sponge and its functional evaluation in modulating contact activation haemostasis.
    Journal of biomaterials applications, 2023, Volume: 38, Issue:2

    Even though it is a common occurrence in practice, maintaining haemostasis can sometimes become a challenging issue in case of trauma, perioperative period, coagulation disorders, cancers, etc. Hemostatic materials are extensively used to assist in the cessation of bleeding. However, the definition of efficiency of haemostasis varies between intended procedures. This paper explores the feasibility of incorporating agents to increase the efficiency of local haemostasis. Pectin or β -D galacto hexopyranuronic acid/β Gal A, a structural polysaccharide widely present in terrestrial plants having an intrinsic hemostatic potential, is blended with gelatin and is explored in modulating passive haemostasis. The sponges are physico chemically characterized, and their hemostatic efficiency is evaluated in vitro using various assays. Biocompatibility evaluation is done by in vitro cytotoxicity assay. The results suggest that this biopolymer combination is a promising candidate for hemostatic control.

    Topics: Gelatin; Hemorrhage; Hemostasis; Hemostatics; Humans; Pectins

2023
Complexation of pectin with macro- and microelements. Antianemic activity of Na, Fe and Na, Ca, Fe complexes.
    Carbohydrate polymers, 2015, Dec-10, Volume: 134

    New water-soluble pectin complexes with Ca(2+), Mg(2+), Co(2+), Cu(2+), Fe(2+), Mn(2+), Zn(2+) on the basis of pectin biopolymer have been synthesized and successfully tested on white rats. For a starting, we have obtained a sodium pectate to enhance solubility of target complexes as a whole. Shortly afterwards, running the reaction of ligand exchange of Nа(+) ions with corresponding s-, d- metal cations we were able to synthesize new pectin complexes. The ranges of s-, d-metals salts concentrations were detected experimentally, in which the selective formation of water-soluble complexes occurred. Antianemic effect of new pectin complexes with Na, Fe and Na, Ca, Fe was investigated on white rats with posthemorrhagic anemia. Under the effect of complexes, the improvement of animals and prevention of erythropoiesis disorders were observed. Antianemic effect of the complexes manifested itself in the doses equivalent to 25% or 50% of the iron daily rate, recommended in the treatment of iron-deficiency anemia with the drugs based on iron sulphate.

    Topics: Anemia; Animals; Calcium; Hemorrhage; Iron; Organometallic Compounds; Pectins; Rats; Sodium

2015
Influence of molecular weight of chemically sulfated citrus pectin fractions on their antithrombotic and bleeding effects.
    Thrombosis and haemostasis, 2009, Volume: 101, Issue:5

    Evaluated were the anticoagulant and antithrombotic activities, and bleeding effect of two chemically sulfated polysaccharides, obtained from citric pectin, with different average molar masses. Both low-molecular-weight (Pec-LWS, 3,600 g/mol) and high-molecular-weight sulfated pectins (Pec-HWS, 12,000 g/mol) had essentially the same structure, consisting of a (1-->4)-linked alpha-D-GalpA chain with almost all its HO-2 and HO-3 groups substituted by sulfate. Both polysaccharides had anticoagulant activity in vitro, although Pec-HWS was a more potent antithrombotic agent in vivo, giving rise to total inhibition of venous thrombosis at a dose of 3.5 mg/kg body weight. Surprisingly, in contrast with heparin, Pec-HWS and Pec-LWS are able to directly inhibit alpha-thrombin and factor Xa by a mechanism independent of antithrombin (AT) and/or heparin co-factor II (HCII). Moreover, Pec-HWS provided a lower risk of bleeding than heparin at a dose of 100% effectiveness against venous thrombosis, indicating it to be a promising antithrombotic agent.

    Topics: Animals; Anticoagulants; Blood Coagulation; Citrus sinensis; Disease Models, Animal; Dose-Response Relationship, Drug; Factor Xa Inhibitors; Female; Fibrinolytic Agents; Hemorrhage; Humans; Male; Molecular Weight; Pectins; Platelet Aggregation; Rats; Rats, Wistar; Structure-Activity Relationship; Sulfates; Thrombin; Venous Thrombosis

2009
[3 Cases of successful arrest of hemorrhage in hemophilia with the aid of hemophobin].
    Pediatriia, 1960, Volume: 38

    Topics: Hemophilia A; Hemorrhage; Hemostatics; Humans; Law Enforcement; Medicine; Pectins

1960
Effect of treated polygalacturonic acid on blood volume loss in the rat following traumatic injury.
    Circulation research, 1958, Volume: 6, Issue:4

    Topics: Animals; Blood Volume; Hemorrhage; Hemostasis; Pectins; Rats

1958
[Our experience in the treatment of some hemorrhagic syndromes with solutions of pectin and vitamin C].
    Medicamenta, 1952, Jan-20, Volume: 10, Issue:212

    Topics: Ascorbic Acid; Hemorrhage; Humans; Pectins; Solutions; Syndrome; Vitamins

1952