pectins has been researched along with Cystic-Fibrosis* in 2 studies
2 other study(ies) available for pectins and Cystic-Fibrosis
| Article | Year |
|---|---|
Alginate lyase and ciprofloxacin co-immobilization on biopolymeric microspheres for cystic fibrosis treatment.
A new formulation is described based on biopolymeric microspheres containing alginate lyase (AL) and ciprofloxacin (Cip) for sustainable oral delivery in CF patients. Alginate (ALG) and high-methoxyl pectin (HMP) are selected as the biopolymers to develop a composite matrix. ALG microspheres coated with HMP and ALG-HMP blend are gelled in water/organic solvents mixtures, obtaining Cip encapsulations from 46.0 to 100.0%. ALG-HMP shows a Cip sustainable release profile and is able to encapsulate 90.0% of AL, showing 76.0% enzyme activity after release under simulated intestinal conditions. The developed system is a promising delivery carrier to treat chronic infection of Pseudomonas aeruginosa and to reduce the viscoelasticity of the mucus accumulated into intestine of CF patients. Topics: Biopolymers; Ciprofloxacin; Cystic Fibrosis; Enzymes, Immobilized; Humans; Hydrogen-Ion Concentration; Kinetics; Microscopy, Electron, Scanning; Microspheres; Pectins; Polysaccharide-Lyases; Propylene Glycol; Solvents | 2013 |
[Studies in vivo of intestinal hydrolysis of starch in childhood].
Topics: Carbohydrate Metabolism, Inborn Errors; Carbohydrates; Celiac Disease; Child, Preschool; Cystic Fibrosis; Humans; Infant; Intestinal Absorption; Intestinal Secretions; Pectins; Starch | 1967 |