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pd168393 and Disease Models, Animal

pd168393 has been researched along with Disease Models, Animal in 6 studies

PD 168393 : A member of the class of quinazolines carrying bromoanilino and acrylamido substituents at positions 4 and 6 respectively.

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"PD168393 was used to inhibit EGFR signaling activation."1.40Epidermal growth factor receptor inhibitor ameliorates excessive astrogliosis and improves the regeneration microenvironment and functional recovery in adult rats following spinal cord injury. ( Li, JJ; Li, ZW; Mao, XQ; Shi, GF; Wang, F; Wang, L; Wang, Q; Wu, JJ; Zhang, JP; Zou, J, 2014)
"PD168393, an EGFRI, was applied topically to the ear skin of mice with or without mast cell deficiency."1.37Phenylbutyrate suppresses distinct skin reactions that are enhanced by blockade of epidermal growth factor receptor signaling. ( Chung, YL; Pui, NN, 2011)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's4 (66.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W1
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Hsieh, TF1
Chen, CC1
Ma, WL1
Chuang, WM1
Hung, XF1
Tsai, YR1
Lin, MH1
Zhang, Q1
Zhang, C1
Chang, C1
Shyr, CR1
Li, ZW1
Li, JJ1
Wang, L1
Zhang, JP1
Wu, JJ1
Mao, XQ1
Shi, GF1
Wang, Q1
Wang, F1
Zou, J1
Zhang, S1
Ju, P1
Tjandra, E1
Yeap, Y1
Owlanj, H1
Feng, Z1
Chung, YL1
Pui, NN1
Erschbamer, M1
Pernold, K1
Olson, L1

Other Studies

6 other studies available for pd168393 and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
Epidermal growth factor enhances androgen receptor‑mediated bladder cancer progression and invasion via potentiation of AR transactivation.
    Oncology reports, 2013, Volume: 30, Issue:6

    Topics: Androgens; Animals; Butylhydroxybutylnitrosamine; Carcinogenesis; Castration; Disease Models, Animal

2013
Epidermal growth factor receptor inhibitor ameliorates excessive astrogliosis and improves the regeneration microenvironment and functional recovery in adult rats following spinal cord injury.
    Journal of neuroinflammation, 2014, Apr-05, Volume: 11

    Topics: Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Disease Models, Animal; ErbB Receptors; Expl

2014
Inhibition of Epidermal Growth Factor Receptor Improves Myelination and Attenuates Tissue Damage of Spinal Cord Injury.
    Cellular and molecular neurobiology, 2016, Volume: 36, Issue:7

    Topics: Animals; Astrocytes; Axons; Disease Models, Animal; ErbB Receptors; Female; Mice; Myelin Sheath; Neu

2016
Phenylbutyrate suppresses distinct skin reactions that are enhanced by blockade of epidermal growth factor receptor signaling.
    Journal of dermatological science, 2011, Volume: 64, Issue:3

    Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents; Cells, Cultured; Chemokine CCL2; Derma

2011
Inhibiting epidermal growth factor receptor improves structural, locomotor, sensory, and bladder recovery from experimental spinal cord injury.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Jun-13, Volume: 27, Issue:24

    Topics: Analysis of Variance; Animals; Behavior, Animal; Disease Models, Animal; ErbB Receptors; Female; In

2007