pd 98059 has been researched along with Vitreoretinopathy, Proliferative in 2 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
Vitreoretinopathy, Proliferative: Vitreoretinal membrane shrinkage or contraction secondary to the proliferation of primarily retinal pigment epithelial cells and glial cells, particularly fibrous astrocytes, followed by membrane formation. The formation of fibrillar collagen and cellular proliferation appear to be the basis for the contractile properties of the epiretinal and vitreous membranes.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weng, CY | 1 |
| Kothary, PC | 1 |
| Verkade, AJ | 1 |
| Reed, DM | 1 |
| Del Monte, MA | 1 |
| Bando, H | 1 |
| Ikuno, Y | 1 |
| Hori, Y | 1 |
| Sayanagi, K | 1 |
| Tano, Y | 1 |
2 other studies available for pd 98059 and Vitreoretinopathy, Proliferative
| Article | Year |
|---|---|
MAP kinase pathway is involved in IGF-1-stimulated proliferation of human retinal pigment epithelial cells (hRPE).
Topics: Cell Culture Techniques; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Extrac | 2009 |
Mitogen-activated protein kinase (MAPK) and phosphatidylinositol-3 kinase (PI3K) pathways differently regulate retinal pigment epithelial cell-mediated collagen gel contraction.
Topics: Androstadienes; Cell Line; Collagen; Enzyme Inhibitors; Extracellular Matrix; Flavonoids; Flow Cytom | 2006 |