pd 98059 has been researched along with Thyroid Neoplasms in 5 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
Thyroid Neoplasms: Tumors or cancer of the THYROID GLAND.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the role of PKCdelta in thyroid cancer cells, we used a replication-deficient adenovirus (PKCdeltaAdV), to tightly control PKCdelta expression." | 1.33 | Activation of protein kinase C delta induces growth arrest in NPA thyroid cancer cells through extracellular signal-regulated kinase mitogen-activated protein kinase. ( Fujii, T; Koike, K; Kuwano, M; Nakamura, AM; Shirouzu, K; Yamana, H; Yokoyama, G, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, Z | 1 |
| Falola, J | 1 |
| Zhu, X | 1 |
| Gu, Y | 1 |
| Kim, LT | 2 |
| Sarosi, GA | 1 |
| Anthony, T | 1 |
| Nwariaku, FE | 2 |
| Panta, GR | 1 |
| Du, L | 1 |
| Koike, K | 1 |
| Fujii, T | 1 |
| Nakamura, AM | 1 |
| Yokoyama, G | 1 |
| Yamana, H | 1 |
| Kuwano, M | 1 |
| Shirouzu, K | 1 |
| Henderson, YC | 1 |
| Fredrick, MJ | 1 |
| Clayman, GL | 1 |
| Saavedra, HI | 1 |
| Knauf, JA | 1 |
| Shirokawa, JM | 1 |
| Wang, J | 1 |
| Ouyang, B | 1 |
| Elisei, R | 1 |
| Stambrook, PJ | 1 |
| Fagin, JA | 1 |
5 other studies available for pd 98059 and Thyroid Neoplasms
| Article | Year |
|---|---|
Antiproliferative effects of Src inhibition on medullary thyroid cancer.
Topics: Apoptosis; Carcinoma, Medullary; Cell Division; Cell Line, Tumor; CSK Tyrosine-Protein Kinase; Enzym | 2004 |
Direct phosphorylation of proliferative and survival pathway proteins by RET.
Topics: Carcinoma, Medullary; Cell Line, Tumor; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinase | 2005 |
Activation of protein kinase C delta induces growth arrest in NPA thyroid cancer cells through extracellular signal-regulated kinase mitogen-activated protein kinase.
Topics: Adenoviridae; Breast Neoplasms; Carcinoma; Carcinoma, Papillary; Cell Cycle; Cell Line, Tumor; Cycli | 2006 |
Differential responses of human papillary thyroid cancer cell lines carrying the RET/PTC1 rearrangement or a BRAF mutation to MEK1/2 inhibitors.
Topics: Butadienes; Carcinoma, Papillary; Cell Division; Cell Line, Tumor; Flavonoids; Gene Rearrangement; H | 2007 |
The RAS oncogene induces genomic instability in thyroid PCCL3 cells via the MAPK pathway.
Topics: Animals; Apoptosis; Cell Nucleus; Chromosomal Proteins, Non-Histone; Doxycycline; Enzyme Inhibitors; | 2000 |