pd 98059 has been researched along with Spinal Cord Injuries in 7 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
Spinal Cord Injuries: Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).
| Excerpt | Relevance | Reference |
|---|---|---|
| "We established a spinal cord contusion model of SCI in all experimental groups except controls, in which only a laminectomy was performed." | 1.40 | Anti-apoptotic signal transduction mechanism of electroacupuncture in acute spinal cord injury. ( Disheng, Y; Jinwei, X; Liang, Z; Mengxuan, D; Renfu, Q; Rongliang, C; Zongbao, Y, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Xue, W | 1 |
| Zhao, Y | 1 |
| Xiao, Z | 1 |
| Wu, X | 1 |
| Ma, D | 1 |
| Han, J | 1 |
| Li, X | 1 |
| Xue, X | 1 |
| Yang, Y | 1 |
| Fang, Y | 1 |
| Fan, C | 1 |
| Liu, S | 1 |
| Xu, B | 1 |
| Han, S | 1 |
| Chen, B | 1 |
| Zhang, H | 1 |
| Fan, Y | 1 |
| Liu, W | 1 |
| Dong, Q | 1 |
| Dai, J | 2 |
| Li, J | 1 |
| Jia, Z | 1 |
| Zhang, Q | 1 |
| Kong, J | 1 |
| Fan, Z | 1 |
| Li, G | 1 |
| Renfu, Q | 1 |
| Rongliang, C | 1 |
| Mengxuan, D | 1 |
| Liang, Z | 1 |
| Jinwei, X | 1 |
| Zongbao, Y | 1 |
| Disheng, Y | 1 |
| Latini, L | 1 |
| Bisicchia, E | 1 |
| Sasso, V | 1 |
| Chiurchiù, V | 1 |
| Cavallucci, V | 1 |
| Molinari, M | 1 |
| Maccarrone, M | 1 |
| Viscomi, MT | 1 |
| Shi, Y | 1 |
| Quan, R | 1 |
| Li, C | 1 |
| Zhang, L | 1 |
| Du, M | 1 |
| Xu, J | 1 |
| Yang, Z | 1 |
| Yang, D | 1 |
| Codeluppi, S | 1 |
| Svensson, CI | 1 |
| Hefferan, MP | 1 |
| Valencia, F | 1 |
| Silldorff, MD | 1 |
| Oshiro, M | 1 |
| Marsala, M | 1 |
| Pasquale, EB | 1 |
| Kobayashi, A | 1 |
| Shinoda, M | 1 |
| Sessle, BJ | 1 |
| Honda, K | 1 |
| Imamura, Y | 1 |
| Hitomi, S | 1 |
| Tsuboi, Y | 1 |
| Okada-Ogawa, A | 1 |
| Iwata, K | 1 |
7 other studies available for pd 98059 and Spinal Cord Injuries
| Article | Year |
|---|---|
Epidermal growth factor receptor-extracellular-regulated kinase blockade upregulates TRIM32 signaling cascade and promotes neurogenesis after spinal cord injury.
Topics: Animals; Cells, Cultured; Cetuximab; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Fem | 2020 |
Inhibition of ERK1/2 phosphorylation attenuates spinal cord injury induced astrocyte activation and inflammation through negatively regulating aquaporin-4 in rats.
Topics: Animals; Aquaporin 4; Astrocytes; Cell Proliferation; Disease Models, Animal; Female; Flavonoids; In | 2021 |
Anti-apoptotic signal transduction mechanism of electroacupuncture in acute spinal cord injury.
Topics: Animals; Apoptosis; Caspase 3; Chromones; Cytochromes c; Electroacupuncture; Female; Flavonoids; Mal | 2014 |
Cannabinoid CB2 receptor (CB2R) stimulation delays rubrospinal mitochondrial-dependent degeneration and improves functional recovery after spinal cord hemisection by ERK1/2 inactivation.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cytochromes c; Flavonoids; Indoles; Male; | 2014 |
The study of traditional Chinese medical elongated-needle therapy promoting neurological recovery mechanism after spinal cord injury in rats.
Topics: Acupuncture Therapy; Animals; bcl-2-Associated X Protein; Caspase 3; Chromones; Cytochromes c; Cytok | 2016 |
The Rheb-mTOR pathway is upregulated in reactive astrocytes of the injured spinal cord.
Topics: Analysis of Variance; Animals; Astrocytes; Cells, Cultured; Chromones; Disease Models, Animal; Enzym | 2009 |
Mechanisms involved in extraterritorial facial pain following cervical spinal nerve injury in rats.
Topics: Animals; Astrocytes; Behavior, Animal; Cervical Vertebrae; Extracellular Signal-Regulated MAP Kinase | 2011 |