pd 98059 has been researched along with Retinitis Pigmentosa in 1 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
Retinitis Pigmentosa: Hereditary, progressive degeneration of the retina due to death of ROD PHOTORECEPTORS initially and subsequent death of CONE PHOTORECEPTORS. It is characterized by deposition of pigment in the retina.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Galán, A | 1 |
| Jmaeff, S | 1 |
| Barcelona, PF | 1 |
| Brahimi, F | 1 |
| Sarunic, MV | 1 |
| Saragovi, HU | 1 |
1 other study available for pd 98059 and Retinitis Pigmentosa
| Article | Year |
|---|---|
In retinitis pigmentosa TrkC.T1-dependent vectorial Erk activity upregulates glial TNF-α, causing selective neuronal death.
Topics: Animals; Cell Death; Disease Models, Animal; Ependymoglial Cells; Extracellular Signal-Regulated MAP | 2017 |