pd 98059 has been researched along with Precursor Cell Lymphoblastic Leukemia-Lymphoma in 5 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
Precursor Cell Lymphoblastic Leukemia-Lymphoma: A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, QY | 1 |
| Wei, XD | 1 |
| Chen, L | 1 |
| Yin, QS | 1 |
| Juarez, JG | 1 |
| Thien, M | 1 |
| Dela Pena, A | 1 |
| Baraz, R | 1 |
| Bradstock, KF | 1 |
| Bendall, LJ | 1 |
| Rambal, AA | 1 |
| Panaguiton, ZL | 1 |
| Kramer, L | 1 |
| Grant, S | 1 |
| Harada, H | 1 |
| Barata, JT | 1 |
| Silva, A | 1 |
| Brandao, JG | 1 |
| Nadler, LM | 1 |
| Cardoso, AA | 1 |
| Boussiotis, VA | 1 |
| Wall, NR | 1 |
| Mohammad, RM | 1 |
| Al-Katib, AM | 1 |
5 other studies available for pd 98059 and Precursor Cell Lymphoblastic Leukemia-Lymphoma
| Article | Year |
|---|---|
[Inhibitory effect of PD98059 on MAPK signaling pathway in acute lymphocytic leukemia cells].
Topics: Flavonoids; Humans; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Precursor Cell Lymphobla | 2013 |
CXCR4 mediates the homing of B cell progenitor acute lymphoblastic leukaemia cells to the bone marrow via activation of p38MAPK.
Topics: Animals; B-Lymphocytes; Benzylamines; Bone Marrow; Cell Line, Tumor; Chemokine CXCL12; Chemotaxis, L | 2009 |
MEK inhibitors potentiate dexamethasone lethality in acute lymphoblastic leukemia cells through the pro-apoptotic molecule BIM.
Topics: Apoptosis; Apoptosis Regulatory Proteins; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associat | 2009 |
Activation of PI3K is indispensable for interleukin 7-mediated viability, proliferation, glucose use, and growth of T cell acute lymphoblastic leukemia cells.
Topics: Antigens, CD; Antigens, Differentiation, B-Lymphocyte; Antigens, Differentiation, T-Lymphocyte; Cell | 2004 |
Mitogen-activated protein kinase is required for bryostatin 1-induced differentiation of the human acute lymphoblastic leukemia cell line Reh.
Topics: Bacterial Proteins; Binding Sites; Blotting, Western; Bryostatins; Cell Differentiation; Enzyme Acti | 2001 |