pd 98059 has been researched along with Pre-Eclampsia in 2 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
Pre-Eclampsia: A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Therefore, decreased VEGF bioavailability during preeclampsia may result in higher vulnerability to placental oxidative cell damage and a further reduction of VEGF bioavailability, a vicious circle that may end up in preeclampsia." | 1.37 | Interplay between vascular endothelial growth factor (VEGF) and nuclear factor erythroid 2-related factor-2 (Nrf2): implications for preeclampsia. ( Fragoulis, A; Kweider, N; Pecks, U; Pufe, T; Rath, W; Rosen, C; Wruck, CJ, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Deng, Q | 1 |
| Chen, Y | 1 |
| Yin, N | 1 |
| Shan, N | 1 |
| Luo, X | 2 |
| Yuan, Y | 1 |
| Liu, Y | 1 |
| Liu, X | 1 |
| Qi, H | 1 |
| Kweider, N | 1 |
| Fragoulis, A | 1 |
| Rosen, C | 1 |
| Pecks, U | 1 |
| Rath, W | 1 |
| Pufe, T | 1 |
| Wruck, CJ | 1 |
2 other studies available for pd 98059 and Pre-Eclampsia
| Article | Year |
|---|---|
The Role of MGAT5 in Human Umbilical Vein Endothelial Cells.
Topics: Adult; Apoptosis; Decidua; Female; Flavonoids; Gene Knockdown Techniques; Human Umbilical Vein Endot | 2017 |
Interplay between vascular endothelial growth factor (VEGF) and nuclear factor erythroid 2-related factor-2 (Nrf2): implications for preeclampsia.
Topics: Butadienes; Cell Line, Tumor; Cell Survival; Enzyme-Linked Immunosorbent Assay; Female; Flavonoids; | 2011 |