pd 98059 has been researched along with Polycystic Ovary Syndrome in 3 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
Polycystic Ovary Syndrome: A complex disorder characterized by infertility, HIRSUTISM; OBESITY; and various menstrual disturbances such as OLIGOMENORRHEA; AMENORRHEA; ANOVULATION. Polycystic ovary syndrome is usually associated with bilateral enlarged ovaries studded with atretic follicles, not with cysts. The term, polycystic ovary, is misleading.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Qi, J | 1 |
| Li, J | 1 |
| Wang, Y | 1 |
| Wang, W | 1 |
| Zhu, Q | 1 |
| He, Y | 1 |
| Lu, Y | 1 |
| Wu, H | 1 |
| Li, X | 1 |
| Zhu, Z | 1 |
| Ding, Y | 1 |
| Xu, R | 1 |
| Sun, Y | 1 |
| Munir, I | 1 |
| Yen, HW | 1 |
| Geller, DH | 1 |
| Torbati, D | 1 |
| Bierden, RM | 1 |
| Weitsman, SR | 1 |
| Agarwal, SK | 1 |
| Magoffin, DA | 1 |
| Nelson-Degrave, VL | 1 |
| Wickenheisser, JK | 1 |
| Hendricks, KL | 1 |
| Asano, T | 1 |
| Fujishiro, M | 1 |
| Legro, RS | 1 |
| Kimball, SR | 1 |
| Strauss, JF | 1 |
| McAllister, JM | 1 |
3 other studies available for pd 98059 and Polycystic Ovary Syndrome
| Article | Year |
|---|---|
Novel role of CXCL14 in modulating STAR expression in luteinized granulosa cells: implication for progesterone synthesis in PCOS patients.
Topics: Adult; Anthracenes; Cells, Cultured; Chemokines, CXC; Cholesterol Side-Chain Cleavage Enzyme; Cyclic | 2021 |
Insulin augmentation of 17alpha-hydroxylase activity is mediated by phosphatidyl inositol 3-kinase but not extracellular signal-regulated kinase-1/2 in human ovarian theca cells.
Topics: Androgens; Cells, Cultured; Colforsin; Enzyme Inhibitors; Female; Flavonoids; Gene Expression Regula | 2004 |
Alterations in mitogen-activated protein kinase kinase and extracellular regulated kinase signaling in theca cells contribute to excessive androgen production in polycystic ovary syndrome.
Topics: Adenoviridae; Androgens; Animals; Blotting, Western; Cell Line; Cells, Cultured; Dehydroepiandroster | 2005 |