pd 98059 has been researched along with Pituitary Neoplasms in 8 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
Pituitary Neoplasms: Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Horiguchi, K | 1 |
| Yamada, M | 1 |
| Satoh, T | 1 |
| Hashimoto, K | 1 |
| Hirato, J | 1 |
| Tosaka, M | 1 |
| Yamada, S | 1 |
| Mori, M | 1 |
| Petiti, JP | 1 |
| Gutiérrez, S | 1 |
| De Paul, AL | 1 |
| Andreoli, V | 1 |
| Palmeri, CM | 1 |
| Sosa, Ldel V | 1 |
| Bocco, JL | 1 |
| Torres, AI | 1 |
| Niiori-Onishi, A | 1 |
| Iwasaki, Y | 1 |
| Mutsuga, N | 1 |
| Oiso, Y | 1 |
| Inoue, K | 1 |
| Saito, H | 1 |
| Li, H | 1 |
| Robinson, PJ | 1 |
| Kawashima, S | 1 |
| Funder, JW | 1 |
| Liu, JP | 1 |
| Kanasaki, H | 1 |
| Fukunaga, K | 1 |
| Takahashi, K | 1 |
| Miyazaki, K | 1 |
| Miyamoto, E | 1 |
| Wang, YH | 1 |
| Maurer, RA | 2 |
| Kievit, P | 1 |
| Lauten, JD | 1 |
| Manfroid, I | 1 |
| Martial, JA | 1 |
| Muller, M | 1 |
8 other studies available for pd 98059 and Pituitary Neoplasms
| Article | Year |
|---|---|
Transcriptional activation of the mixed lineage leukemia-p27Kip1 pathway by a somatostatin analogue.
Topics: Adult; Androstadienes; Antineoplastic Agents, Hormonal; Base Sequence; Cell Line, Tumor; Cyclin-Depe | 2009 |
GH3B6 pituitary tumor cell proliferation is mediated by PKCalpha and PKCepsilon via ERK 1/2-dependent pathway.
Topics: Animals; Bromodeoxyuridine; Cell Proliferation; Flavonoids; Flow Cytometry; Mitogen-Activated Protei | 2010 |
Molecular mechanisms of the negative effect of insulin-like growth factor-I on growth hormone gene expression in MtT/S somatotroph cells.
Topics: Androstadienes; Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Gene Expre | 1999 |
Differential regulation of MAP kinase activity by corticotropin-releasing hormone in normal and neoplastic corticotropes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Atrial Natriuretic Factor; Calcium-Calmodulin-Depen | 1998 |
Mitogen-activated protein kinase activation by stimulation with thyrotropin-releasing hormone in rat pituitary GH3 cells.
Topics: Androstadienes; Animals; Benzylamines; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cyclic | 1999 |
A role for the mitogen-activated protein kinase in mediating the ability of thyrotropin-releasing hormone to stimulate the prolactin promoter.
Topics: Animals; Binding Sites; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; DNA-Binding Proteins; | 1999 |
Analysis of the role of the mitogen-activated protein kinase in mediating cyclic-adenosine 3',5'-monophosphate effects on prolactin promoter activity.
Topics: Animals; Binding Sites; Colforsin; CREB-Binding Protein; Cyclic AMP; Cyclic AMP-Dependent Protein Ki | 2001 |
Inhibition of protein phosphatase PP1 in GH3B6, but not in GH3 cells, activates the MEK/ERK/c-fos pathway and the human prolactin promoter, involving the coactivator CPB/p300.
Topics: Animals; DNA-Binding Proteins; E1A-Associated p300 Protein; Enzyme Inhibitors; Flavonoids; Humans; I | 2001 |